Luke Anthony John O'Neill (Luke A J O'Neill, L A J O'Neill, Luke A J O' Neill, Luke O'Neill, Luke A O'Neill)

ORCID

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 31

Top Venues

Nature

Nature communications

Nature immunology

Immunological reviews

University of London (PHD)

This page only lists publications with an associated author ORCID identifier.

Education History

University of London Sep 01 1985 - Jun 30 1988

United Kingdom

PHD :: Pharmacology

Publications

Michael P Murphy, Luke Anthony John O'Neill
A break in mitochondrial endosymbiosis as a basis for inflammatory diseases. Nature 626 (7998) (2024)
Shane M O'Carroll, Fiona D R Henkel, Luke Anthony John O'Neill
Metabolic regulation of type I interferon production. Immunological reviews (2024)
Naziia Kurmasheva, Aida Said, Boaz Wong, Priscilla Kinderman, Xiaoying Han, Anna H F Rahimic, Alena Kress, Madalina E Carter-Timofte, Emilia Holm, Demi van der Horst, Christoph F Kollmann, Zhenlong Liu, Chen Wang, Huy-Dung Hoang, Elina Kovalenko, Maria Chrysopoulou, Krishna Sundar Twayana, Rasmus N Ottosen, Esben B Svenningsen, Fabio Begnini, Anders E Kiib, Florian E H Kromm, Hauke Johannes Weiss, Daniele Di Carlo, Michela Muscolini, Maureen Higgins, Mirte van der Heijden, Angelina Bardoul, Tong Tong, Attila Ozsvar, Wen-Hsien Hou, Vivien R Schack, Christian Kanstrup Holm, Yunan Zheng, Melanie Ruzek, Joanna M Kalucka, Laureano de la Vega, Walid A M Elgaher, Anders Rosendal Korshoej, Rongtuan Lin, John Hiscott, Thomas B Poulsen, Luke Anthony John O'Neill, Dominic Guy Roy, Markus M Rinschen, Nadine van Montfoort, Jean-Simon Diallo, Henner F Farin, Tommy Alain, David Olagnier
Octyl itaconate enhances VSVΔ51 oncolytic virotherapy by multitarget inhibition of antiviral and inflammatory pathways. Nature communications 15 (1) (2024)
Michael P Murphy, Luke Anthony John O'Neill
A break in mitochondrial endosymbiosis as a basis for inflammatory diseases. Nature 626 (7998) (2024)
Naziia Kurmasheva, Aida Said, Boaz Wong, Priscilla Kinderman, Xiaoying Han, Anna H F Rahimic, Alena Kress, Madalina E Carter-Timofte, Emilia Holm, Demi van der Horst, Christoph F Kollmann, Zhenlong Liu, Chen Wang, Huy-Dung Hoang, Elina Kovalenko, Maria Chrysopoulou, Krishna Sundar Twayana, Rasmus N Ottosen, Esben B Svenningsen, Fabio Begnini, Anders E Kiib, Florian E H Kromm, Hauke Johannes Weiss, Daniele Di Carlo, Michela Muscolini, Maureen Higgins, Mirte van der Heijden, Angelina Bardoul, Tong Tong, Attila Ozsvar, Wen-Hsien Hou, Vivien R Schack, Christian Kanstrup Holm, Yunan Zheng, Melanie Ruzek, Joanna M Kalucka, Laureano de la Vega, Walid A M Elgaher, Anders Rosendal Korshoej, Rongtuan Lin, John Hiscott, Thomas B Poulsen, Luke Anthony John O'Neill, Dominic Guy Roy, Markus M Rinschen, Nadine van Montfoort, Jean-Simon Diallo, Henner F Farin, Tommy Alain, David Olagnier
Octyl itaconate enhances VSVΔ51 oncolytic virotherapy by multitarget inhibition of antiviral and inflammatory pathways. Nature communications 15 (1) (2024)
Shane M O'Carroll, Fiona D R Henkel, Luke Anthony John O'Neill
Metabolic regulation of type I interferon production. Immunological reviews 323 (1) (2024)
Michael P Murphy, Luke Anthony John O'Neill
A break in mitochondrial endosymbiosis as a basis for inflammatory diseases. Nature 626 (7998) (2024)
Anne F McGettrick, L A Bourner, F C Dorsey, Luke Anthony John O'Neill
Metabolic Messengers: itaconate. Nature metabolism (2024)
Michael P Murphy, Luke Anthony John O'Neill
A break in mitochondrial endosymbiosis as a basis for inflammatory diseases. Nature 626 (7998) (2024)
Shane M O'Carroll, Fiona D R Henkel, Luke Anthony John O'Neill
Metabolic regulation of type I interferon production. Immunological reviews 323 (1) (2024)
Naziia Kurmasheva, Aida Said, Boaz Wong, Priscilla Kinderman, Xiaoying Han, Anna H F Rahimic, Alena Kress, Madalina E Carter-Timofte, Emilia Holm, Demi van der Horst, Christoph F Kollmann, Zhenlong Liu, Chen Wang, Huy-Dung Hoang, Elina Kovalenko, Maria Chrysopoulou, Krishna Sundar Twayana, Rasmus N Ottosen, Esben B Svenningsen, Fabio Begnini, Anders E Kiib, Florian E H Kromm, Hauke Johannes Weiss, Daniele Di Carlo, Michela Muscolini, Maureen Higgins, Mirte van der Heijden, Angelina Bardoul, Tong Tong, Attila Ozsvar, Wen-Hsien Hou, Vivien R Schack, Christian Kanstrup Holm, Yunan Zheng, Melanie Ruzek, Joanna M Kalucka, Laureano de la Vega, Walid A M Elgaher, Anders Rosendal Korshoej, Rongtuan Lin, John Hiscott, Thomas B Poulsen, Luke Anthony John O'Neill, Dominic Guy Roy, Markus M Rinschen, Nadine van Montfoort, Jean-Simon Diallo, Henner F Farin, Tommy Alain, David Olagnier
Octyl itaconate enhances VSVΔ51 oncolytic virotherapy by multitarget inhibition of antiviral and inflammatory pathways. Nature communications 15 (1) (2024)
Naziia Kurmasheva, Aida Said, Boaz Wong, Priscilla Kinderman, Xiaoying Han, Anna H F Rahimic, Alena Kress, Madalina E Carter-Timofte, Emilia Holm, Demi van der Horst, Christoph F Kollmann, Zhenlong Liu, Chen Wang, Huy-Dung Hoang, Elina Kovalenko, Maria Chrysopoulou, Krishna Sundar Twayana, Rasmus N Ottosen, Esben B Svenningsen, Fabio Begnini, Anders E Kiib, Florian E H Kromm, Hauke Johannes Weiss, Daniele Di Carlo, Michela Muscolini, Maureen Higgins, Mirte van der Heijden, Angelina Bardoul, Tong Tong, Attila Ozsvar, Wen-Hsien Hou, Vivien R Schack, Christian Kanstrup Holm, Yunan Zheng, Melanie Ruzek, Joanna M Kalucka, Laureano de la Vega, Walid A M Elgaher, Anders Rosendal Korshoej, Rongtuan Lin, John Hiscott, Thomas B Poulsen, Luke Anthony John O'Neill, Dominic Guy Roy, Markus M Rinschen, Nadine van Montfoort, Jean-Simon Diallo, Henner F Farin, Tommy Alain, David Olagnier
Octyl itaconate enhances VSVΔ51 oncolytic virotherapy by multitarget inhibition of antiviral and inflammatory pathways. Nature communications 15 (1) (2024)
Juliana Escher Toller-Kawahisa, Carlos Hiroji Hiroki, Camila Meirelles de Souza Silva, Daniele Carvalho Nascimento, Gabriel Azevedo Publio, Timna Varela Martins, Luis Eduardo Alves Damasceno, Flávio Protásio Veras, Paula Ramos Viacava, Fábio Yuji Sukesada, Emily Anne Day, Alessia Zotta, Tristram Alexander Jasper Ryan, Rodrigo Moreira da Silva, Thiago Mattar Cunha, Norberto Peporine Lopes, Fernando de Queiroz Cunha, Luke Anthony John O'Neill, José Carlos Alves Filho
The metabolic function of pyruvate kinase M2 regulates reactive oxygen species production and microbial killing by neutrophils. Nature communications 14 (1) (2023)
Tristram Alexander Jasper Ryan, Alexander Hooftman, Aisling M Rehill, Matt D Johansen, Eóin C O' Brien, Juliana E Toller-Kawahisa, Mieszko M Wilk, Emily A Day, Hauke J Weiss, Pourya Sarvari, Emilio G Vozza, Fabian Schramm, Christian G Peace, Alessia Zotta, Stefan Miemczyk, Christina Nalkurthi, Nicole G Hansbro, Gavin McManus, Laura O'Doherty, Siobhan Gargan, Aideen Long, Jean Dunne, Clíona Ní Cheallaigh, Niall Conlon, Michael Carty, Padraic G Fallon, Kingston H G Mills, Emma M Creagh, James S O' Donnell, Paul J Hertzog, Philip Michael Hansbro, Rachel M McLoughlin, Malgorzata Wygrecka, Roger J S Preston, Zbigniew Zasłona, Luke Anthony John O'Neill
Dimethyl fumarate and 4-octyl itaconate are anticoagulants that suppress Tissue Factor in macrophages via inhibition of Type I Interferon. Nature communications 14 (1) (2023)
Alexander Hooftman, Christian G Peace, Dylan Gerard Ryan, Emily Anne Day, Ming Yang, Anne F McGettrick, Maureen Yin, Erica N Montano, Lihong Huo, Juliana E Toller-Kawahisa, Vincent Zecchini, Tristram Alexander Jasper Ryan, Alfonso Bolado Carrancio, Alva M Casey, Hiran A Prag, Ana S H Costa, Gabriela De Los Santos, Mariko Ishimori, Daniel J Wallace, Swamy Venuturupalli, Efterpi Nikitopoulou, Norma Frizzell, Cecilia Johansson, Alexander von Kriegsheim, Michael P Murphy, Caroline Jefferies, Christian Frezza, Luke Anthony John O'Neill
Macrophage fumarate hydratase restrains mtRNA-mediated interferon production. Nature (2023)
Alexander Hooftman, Christian G Peace, Dylan Gerard Ryan, Emily Anne Day, Ming Yang, Anne F McGettrick, Maureen Yin, Erica N Montano, Lihong Huo, Juliana E Toller-Kawahisa, Vincent Zecchini, Tristram Alexander Jasper Ryan, Alfonso Bolado Carrancio, Alva M Casey, Hiran A Prag, Ana S H Costa, Gabriela De Los Santos, Mariko Ishimori, Daniel J Wallace, Swamy Venuturupalli, Efterpi Nikitopoulou, Norma Frizzell, Cecilia Johansson, Alexander von Kriegsheim, Michael P Murphy, Caroline Jefferies, Christian Frezza, Luke Anthony John O'Neill
Macrophage fumarate hydratase restrains mtRNA-mediated interferon production. Nature (2023)
Alexander Hooftman, Christian G Peace, Dylan Gerard Ryan, Emily Anne Day, Ming Yang, Anne F McGettrick, Maureen Yin, Erica N Montano, Lihong Huo, Juliana E Toller-Kawahisa, Vincent Zecchini, Tristram Alexander Jasper Ryan, Alfonso Bolado Carrancio, Alva M Casey, Hiran A Prag, Ana S H Costa, Gabriela De Los Santos, Mariko Ishimori, Daniel J Wallace, Swamy Venuturupalli, Efterpi Nikitopoulou, Norma Frizzell, Cecilia Johansson, Alexander von Kriegsheim, Michael P Murphy, Caroline Jefferies, Christian Frezza, Luke Anthony John O'Neill
Macrophage fumarate hydratase restrains mtRNA-mediated interferon production. Nature 615 (7952) (2023)
Alexander Hooftman, Christian G Peace, Dylan Gerard Ryan, Emily Anne Day, Ming Yang, Anne F McGettrick, Maureen Yin, Erica N Montano, Lihong Huo, Juliana E Toller-Kawahisa, Vincent Zecchini, Tristram Alexander Jasper Ryan, Alfonso Bolado Carrancio, Alva M Casey, Hiran A Prag, Ana S H Costa, Gabriela De Los Santos, Mariko Ishimori, Daniel J Wallace, Swamy Venuturupalli, Efterpi Nikitopoulou, Norma Frizzell, Cecilia Johansson, Alexander von Kriegsheim, Michael P Murphy, Caroline Jefferies, Christian Frezza, Luke Anthony John O'Neill
Macrophage fumarate hydratase restrains mtRNA-mediated interferon production. Nature 615 (7952) (2023)
Alexander Hooftman, Christian G Peace, Dylan Gerard Ryan, Emily Anne Day, Ming Yang, Anne F McGettrick, Maureen Yin, Erica N Montano, Lihong Huo, Juliana E Toller-Kawahisa, Vincent Zecchini, Tristram Alexander Jasper Ryan, Alfonso Bolado Carrancio, Alva M Casey, Hiran A Prag, Ana S H Costa, Gabriela De Los Santos, Mariko Ishimori, Daniel J Wallace, Swamy Venuturupalli, Efterpi Nikitopoulou, Norma Frizzell, Cecilia Johansson, Alexander von Kriegsheim, Michael P Murphy, Caroline Jefferies, Christian Frezza, Luke Anthony John O'Neill
Macrophage fumarate hydratase restrains mtRNA-mediated interferon production. Nature 615 (7952) (2023)
Tristram Alexander Jasper Ryan, Alexander Hooftman, Aisling M Rehill, Matt D Johansen, Eóin C O' Brien, Juliana E Toller-Kawahisa, Mieszko M Wilk, Emily A Day, Hauke J Weiss, Pourya Sarvari, Emilio G Vozza, Fabian Schramm, Christian G Peace, Alessia Zotta, Stefan Miemczyk, Christina Nalkurthi, Nicole G Hansbro, Gavin McManus, Laura O'Doherty, Siobhan Gargan, Aideen Long, Jean Dunne, Clíona Ní Cheallaigh, Niall Conlon, Michael Carty, Padraic G Fallon, Kingston H G Mills, Emma M Creagh, James S O' Donnell, Paul J Hertzog, Philip Michael Hansbro, Rachel M McLoughlin, Malgorzata Wygrecka, Roger J S Preston, Zbigniew Zasłona, Luke Anthony John O'Neill
Publisher Correction: Dimethyl fumarate and 4-octyl itaconate are anticoagulants that suppress Tissue Factor in macrophages via inhibition of Type I Interferon. Nature communications 14 (1) (2023)
Alexander Hooftman, Christian G Peace, Dylan Gerard Ryan, Emily Anne Day, Ming Yang, Anne F McGettrick, Maureen Yin, Erica N Montano, Lihong Huo, Juliana E Toller-Kawahisa, Vincent Zecchini, Tristram Alexander Jasper Ryan, Alfonso Bolado Carrancio, Alva M Casey, Hiran A Prag, Ana S H Costa, Gabriela De Los Santos, Mariko Ishimori, Daniel J Wallace, Swamy Venuturupalli, Efterpi Nikitopoulou, Norma Frizzell, Cecilia Johansson, Alexander von Kriegsheim, Michael P Murphy, Caroline Jefferies, Christian Frezza, Luke Anthony John O'Neill
Macrophage fumarate hydratase restrains mtRNA-mediated interferon production. Nature (2023)
Anne F McGettrick, Luke Anthony John O'Neill
The itaconate family of immunomodulators grows. Nature metabolism 4 (5) (2022)
Juliana E Toller-Kawahisa, Luke Anthony John O'Neill
Creating ATP via creatine kinase B for NLRP3 activation. Nature immunology 23 (5) (2022)
Maziar Divangahi, Peter Aaby, Shabaana Abdul Khader, Luis B Barreiro, Siroon Bekkering, Triantafyllos Chavakis, Reinout van Crevel, Nigel Curtis, Andrew R DiNardo, Mihai G Netea, Raphael Duivenvoorden, Stephanie Fanucchi, Zahi Adel Fayad, Elaine Fuchs, Melanie Anne Hamon, Kate L Jeffrey, Nargis Khan, Leo A B Joosten, Eva Kaufmann, Eicke Latz, Giuseppe Matarese, Jos W M van der Meer, Musa M Mhlanga, Simone J C F M Moorlag, Willem J M Mulder, Shruti Naik, Boris Novakovic, Luke Anthony John O'Neill, Jordi Ochando, Keiko Ozato, Niels P Riksen, Robert Sauerwein, Edward R Sherwood, Andreas Schlitzer, Joachim L Schultze, Michael H Sieweke, Christine Stabell Benn, Henk Stunnenberg, Joseph C Sun, Frank L van de Veerdonk, Sebastian Weis, David L Williams, Ramnik J Xavier, Mihai M Netea
Trained immunity, tolerance, priming and differentiation: distinct immunological processes. Nature immunology 22 (1) (2021)
Emily Anne Day, Luke Anthony John O'Neill
Targeting mitochondria to beat HIV-1. Nature immunology 22 (4) (2021)
Alessia Zotta, Alexander Hooftman, Luke Anthony John O'Neill
SARS-CoV-2 targets MAVS for immune evasion. Nature cell biology 23 (7) (2021)
Christopher D Buckley, Lorna Chernajovsky, Yuti Chernajovsky, Louise K Modis, Luke Anthony John O'Neill, Doug Brown, Rachel Connor, David J C Coutts, Elizabeth A Waterman, Paul P Tak
Immune-mediated inflammation across disease boundaries: breaking down research silos. Nature immunology 22 (11) (2021)
Michael P Murphy, Luke Anthony John O'Neill
How should we talk about metabolism? Nature immunology 21 (7) (2020)
Zbigniew Zasłona, Ewelina Flis, Mieszko M Wilk, Richard G Carroll, Eva M Palsson-McDermott, Mark M Hughes, Ciana Diskin, Kathy Banahan, Dylan G Ryan, Alexander Hooftman, Alicja Misiak, Jay Kearney, Guenter Lochnit, Wilhelm Bertrams, Timm Greulich, Bernd Schmeck, Oliver J McElvaney, Kingston H G Mills, Ed C Lavelle, Malgorzata Wygrecka, Emma M Creagh, Luke Anthony John O'Neill
Caspase-11 promotes allergic airway inflammation. Nature communications 11 (1) (2020)
Christian Schwartz, Tara Moran, Sean P Saunders, Agnieszka Kaszlikowska, Achilleas Floudas, Joana Bom, Gabriel Nunez, Yoichiro Iwakura, Luke Anthony John O'Neill, Alan D Irvine, Andrew N J McKenzie, Graham S Ogg, Patrick T Walsh, Jocelyne Demengeot, Padraic G Fallon
Spontaneous atopic dermatitis in mice with a defective skin barrier is independent of ILC2 and mediated by IL-1β. Allergy 74 (10) (2019)
Mark M Hughes, Luke Anthony John O'Neill
Metabolic regulation of NLRP3. Immunological reviews 281 (1) (2018)

Luke Anthony John O'Neill.css-eqlu8i{font-size:small;padding-left:4px;} (Luke A J O'Neill, L A J O'Neill, Luke A J O' Neill, Luke O'Neill, Luke A O'Neill)

Publication Activity (10 Years)

Top Topics

Top Venues

Luke Anthony John O'Neill (Luke A J O'Neill, L A J O'Neill, Luke A J O' Neill, Luke O'Neill, Luke A O'Neill)