Lynda Coughlan

ORCID

Publication Activity (10 Years)

Years Active: 2019-2023
Publications (10 Years): 16

Top Venues

Nature communications

Science advances

mBio

Microbiology spectrum

Mount Sinai Hospital

Barts Cancer Institute (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Mount Sinai Hospital Feb 06 2017

United States

Assistant Professor :: Dept of Microbiology, Icahn School of Medicine

University of Oxford Aug 01 2012 - Dec 31 2016

United Kingdom

Post-doctoral fellow :: Jenner Institute

University of Glasgow Aug 01 2009 - Jul 25 2012

United Kingdom

Post-doctoral research associate :: Glasgow Cardiovascular Research Centre

Education History

Barts Cancer Institute Sep 01 2005 - Jul 25 2009

United Kingdom

PHD :: Tumour Biology and Molecular Oncology

London School of Hygiene and Tropical Medicine Sep 01 2004 - Aug 30 2005

United Kingdom

MSC

University College Cork Sep 01 1998 - Jun 01 2003

Ireland

BSC :: Microbiology

Publications

Fatima Amanat, Jordan Clark, Juan Manuel Carreño, Shirin Strohmeier, Temima Yellin, Philip S Meade, Disha Bhavsar, Hiromi Muramatsu, Weina Sun, Lynda Coughlan, Norbert Pardi, Florian Krammer
Immunity to Seasonal Coronavirus Spike Proteins Does Not Protect from SARS-CoV-2 Challenge in a Mouse Model but Has No Detrimental Effect on Protection Mediated by COVID-19 mRNA Vaccination. Journal of virology (2023)
Eduard Puente-Massaguer, Kirill A Vasilyev, Annika Beyer, Madhumathi Loganathan, Benjamin Francis, Michael J Scherm, Guha Asthagiri Arunkumar, Irene González Domínguez, Xueyong Zhu, Ian A Wilson, Lynda Coughlan, Weina Sun, Peter Palese, Florian Krammer
Chimeric hemagglutinin split vaccines elicit broadly cross-reactive antibodies and protection against group 2 influenza viruses in mice. Science advances 9 (37) (2023)
Irene González Domínguez, Jose Luis Martínez, Stefan A Slamanig, Nicholas Lemus, Yonghong Liu, Tsoi Ying Lai, Juan Manuel Carreño, Gagandeep Singh, Gagandeep Singh, Michael Schotsaert, Ignacio Mena, Stephen McCroskery, Lynda Coughlan, Florian Krammer, Adolfo García-Sastre, Peter Palese, Weina Sun
Trivalent NDV-HXP-S Vaccine Protects against Phylogenetically Distant SARS-CoV-2 Variants of Concern in Mice. Microbiology spectrum 10 (3) (2022)
Johannes B Goll, Aarti Jain, Carolyn J Albert, Rafael Assis, Rie Nakajima, Algis Jasinskas, Lynda Coughlan, Sami R Cherikh, Casey E Gelber, S Khan, D Huw Davies, Philip Meade, Daniel Stadlbauer, Shirin Strohmeier, Florian Krammer, Wilbur H Chen, Philip L Felgner
The antibody landscapes following AS03 and MF59 adjuvanted H5N1 vaccination. NPJ vaccines 7 (1) (2022)
Alexander T Baker, Ryan J Boyd, Daipayan Sarkar, Alicia Teijeira-Crespo, Chun Kit Chan, Emily Bates, Kasim Waraich, John W Vant, Eric A Wilson, Chloe D Truong, Magdalena Lipka-Lloyd, Petra Fromme, Josh Vincent Vermaas, Dewight R Williams, LeeAnn Machiesky, Meike Heurich, Bolni M Nagalo, Lynda Coughlan, Scott Umlauf, Po-Lin Chiu, Pierre J Rizkallah, Taylor S Cohen, Alan L Parker, Abhishek Singharoy, Mitesh J Borad
ChAdOx1 interacts with CAR and PF4 with implications for thrombosis with thrombocytopenia syndrome. Science advances 7 (49) (2021)
Jenna J Guthmiller, Julianna Han, Henry A Utset, Lei Li, Linda Yu-Ling Lan, Carole Henry, Christopher T Stamper, Meagan McMahon, George O'Dell, Monica L Fernández-Quintero, Alec W Freyn, Fatima Amanat, Olivia Stovicek, Lauren Gentles, Sara T Richey, Alba Torrents de la Peña, Victoria Rosado, Haley L Dugan, Nai-Ying Zheng, Micah E Tepora, Dalia J Bitar, Siriruk Changrob, Shirin Strohmeier, Min Huang, Adolfo García-Sastre, Klaus Roman Liedl, Jesse D Bloom, Raffael Nachbagauer, Peter Palese, Florian Krammer, Lynda Coughlan, Andrew B Ward, Patrick C Wilson
Broadly neutralizing antibodies target a haemagglutinin anchor epitope. Nature 602 (7896) (2021)
Kris M White, Romel Rosales, Soner Yildiz, Thomas Kehrer, Lisa Miorin, Elena Moreno, Sonia Jangra, Melissa B Uccellini, Raveen Rathnasinghe, Lynda Coughlan, Carles Martínez-Romero, Jyoti Batra, Ajda Rojc, Mehdi Bouhaddou, Jacqueline M Fabius, Kirsten Obernier, Marion Dejosez, María José Guillén, Alejandro Losada, Pablo Avilés, Michael Schotsaert, Thomas P Zwaka, Marco Vignuzzi, Kevan M Shokat, Nevan J Krogan, Adolfo García-Sastre
Plitidepsin has potent preclinical efficacy against SARS-CoV-2 by targeting the host protein eEF1A. Science (New York, N.Y.) 371 (6532) (2021)
Pauline Maisonnasse, Yoann Aldon, Aurélien Marc, Romain Marlin, Nathalie Bosquet, Natalia A Kuzmina, Alec W Freyn, Jonne L Snitselaar, Antonio Gonçalves, Tom G Caniels, Judith A Burger, Meliawati Poniman, Ilja Bontjer, Virginie Chesnais, Ségolène Diry, Anton Iershov, Adam J Ronk, Sonia Jangra, Raveen Rathnasinghe, Philip J M Brouwer, Tom P L Bijl, Jelle van Schooten, Mitch Brinkkemper, Hejun Liu, Meng Yuan, Chad E Mire, Mariëlle J van Breemen, Vanessa Contreras, Thibaut Naninck, Julien Lemaître, Nidhal Kahlaoui, Francis Relouzat, Catherine Chapon, Raphaël Ho Tsong Fang, Charlene McDanal, Mary Osei-Twum, Natalie St-Amant, Luc Gagnon, David C Montefiori, Ian A Wilson, Eric Ginoux, Godelieve J de Bree, Adolfo García-Sastre, Michael Schotsaert, Lynda Coughlan, Alexander Bukreyev, Sylvie van der Werf, Jeremie Guedj, Rogier W Sanders, Marit J van Gils, Roger Le Grand
COVA1-18 neutralizing antibody protects against SARS-CoV-2 in three preclinical models. Nature communications 12 (1) (2021)
Haley L Dugan, Jenna J Guthmiller, Philip Arevalo, Min Huang, Yao-Qing Chen, Karlynn E Neu, Carole Henry, Nai-Ying Zheng, Linda Yu-Ling Lan, Micah E Tepora, Olivia Stovicek, Dalia Bitar, Anna-Karin E Palm, Christopher T Stamper, Siriruk Changrob, Henry A Utset, Lynda Coughlan, Florian Krammer, Sarah E Cobey, Patrick C Wilson
Preexisting immunity shapes distinct antibody landscapes after influenza virus infection and vaccination in humans. Science translational medicine 12 (573) (2021)
Fatima Amanat, Shirin Strohmeier, Raveen Rathnasinghe, Michael Schotsaert, Lynda Coughlan, Adolfo García-Sastre, Florian Krammer
Introduction of Two Prolines and Removal of the Polybasic Cleavage Site Lead to Higher Efficacy of a Recombinant Spike-Based SARS-CoV-2 Vaccine in the Mouse Model. mBio 12 (2) (2021)
Fatima Amanat, Shirin Strohmeier, Philip S Meade, Nicholas Dambrauskas, Barbara Mühlemann, Derek J Smith, Vladimir Vigdorovich, D Noah Sather, Lynda Coughlan, Florian Krammer
Vaccination with SARS-CoV-2 variants of concern protects mice from challenge with wild-type virus. PLoS biology 19 (12) (2021)
Weina Sun, Yonghong Liu, Fatima Amanat, Irene González Domínguez, Stephen McCroskery, Stefan A Slamanig, Lynda Coughlan, Victoria Rosado, Nicholas Lemus, Sonia Jangra, Raveen Rathnasinghe, Michael Schotsaert, Jose L Martinez, Kaori Sano, Ignacio Mena, Bruce L Innis, Ponthip Wirachwong, Duong Huu Thai, Ricardo Das Neves Oliveira, Rami Scharf, Richard Hjorth, Rama Raghunandan, Florian Krammer, Adolfo García-Sastre, Peter Palese
A Newcastle disease virus expressing a stabilized spike protein of SARS-CoV-2 induces protective immune responses. Nature communications 12 (1) (2021)
Raffael Nachbagauer, Jodi Feser, Abdollah Naficy, David I Bernstein, Jeffrey Guptill, Emmanuel B Walter, Franceso Berlanda-Scorza, Daniel Stadlbauer, Patrick C Wilson, Teresa Aydillo, Mohammad Amin Behzadi, Disha Bhavsar, Carly Bliss, Christina Capuano, Juan Manuel Carreño, Veronika Chromikova, Carine Claeys, Lynda Coughlan, Alec W Freyn, Christopher Gast, Andres Javier, Kaijun Jiang, Chiara Mariottini, Meagan McMahon, Monica McNeal, Alicia Solórzano, Shirin Strohmeier, Weina Sun, Marie Van der Wielen, Bruce L Innis, Adolfo García-Sastre, Peter Palese, Florian Krammer
A chimeric hemagglutinin-based universal influenza virus vaccine approach induces broad and long-lasting immunity in a randomized, placebo-controlled phase I trial. Nature medicine 27 (1) (2020)
Raveen Rathnasinghe, Shirin Strohmeier, Fatima Amanat, Virginia L Gillespie, Florian Krammer, Adolfo García-Sastre, Lynda Coughlan, Michael Schotsaert, Melissa B Uccellini
Comparison of transgenic and adenovirus hACE2 mouse models for SARS-CoV-2 infection. Emerging microbes & infections 9 (1) (2020)
Juan Manuel Carreño, Jacqueline U McDonald, Tara Hurst, Peter Rigsby, Eleanor Atkinson, Lethia Charles, Raffael Nachbagauer, Mohammad Amin Behzadi, Shirin Strohmeier, Lynda Coughlan, Teresa A Aydillo Gomez, Boerries Brandenburg, Adolfo García-Sastre, Krisztian Kaszas, Min Z Levine, Alessandro Manenti, Adrian B McDermott, Emanuele Montomoli, Leacky Muchene, Sandeep R Narpala, Ranawaka A P M Perera, Nadine C Salisch, Sophie A Valkenburg, Fan Zhou, Othmar G Engelhardt, Florian Krammer
Development and Assessment of a Pooled Serum as Candidate Standard to Measure Influenza A Virus Group 1 Hemagglutinin Stalk-Reactive Antibodies. Vaccines 8 (4) (2020)
Alexander T Baker, Alexander Greenshields-Watson, Lynda Coughlan, James A Davies, Hanni Uusi-Kerttula, David K Cole, Pierre J Rizkallah, Alan L Parker
Diversity within the adenovirus fiber knob hypervariable loops influences primary receptor interactions. Nature communications 10 (1) (2019)

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Publication Activity (10 Years)

Top Topics

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Lynda Coughlan