Manu Shankar-Hari (M Shankar-Hari)

Scopus Author ID Scopus Author ID ResearcherID ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 96

Top Venues

American journal of respiratory and critical care medicine

Thorax

Intensive care medicine

Scientific reports

Guy's and Saint Thomas' NHS Foundation Trust

London School of Hygiene and Tropical Medicine (MSC)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Guy's and Saint Thomas' NHS Foundation Trust May 05 2009

United Kingdom

Consultant in Intensive Care Medicine :: Intensive Care Medicine

King's College London - Guy's Campus Oct 01 2012 - May 01 2016

United Kingdom

PhD Student in Immunology :: Peter Gorer Department of Immunobiology

Guy's and Saint Thomas' NHS Foundation Trust Feb 03 2009 - May 04 2009

United Kingdom

Specialist Registrar :: Anaesthesia

Education History

London School of Hygiene and Tropical Medicine Jun 01 2009 - Oct 01 2013

United Kingdom

MSC :: Epidemiology

Trivandrum Medical College Apr 01 1992 - Jan 01 1998

India

BSC :: Medical School

Publications

Anthony C Gordon, Narges Alipanah-Lechner, Lieuwe D J Bos, Jose Dianti, Janet V Diaz, Simon R Finfer, Tomoko Fujii, Evangelos J Giamarellos-Bourboulis, Ewan C Goligher, Michelle Ng Gong, Eleni Karakike, Vincent X Liu, Nuttha Lumlertgul, John C Marshall, David K Menon, Nuala J Meyer, Elizabeth S Munroe, Sheila Nainan Myatra, Marlies Ostermann, Hallie C Prescott, Adrienne G Randolph, Edward J Schenck, Christopher W Seymour, Manu Shankar-Hari, Mervyn Singer, Marry R Smit, Aiko Tanaka, Fabio S Taccone, B Taylor Thompson, Lisa K Torres, Tom van der Poll, Jean-Louis Vincent, Carolyn S Calfee
From ICU Syndromes to ICU Subphenotypes: Consensus Report and Recommendations for Developing Precision Medicine in the ICU. American journal of respiratory and critical care medicine 210 (2) (2024)
Anthony C Gordon, Narges Alipanah-Lechner, Lieuwe D J Bos, Jose Dianti, Janet V Diaz, Simon R Finfer, Tomoko Fujii, Evangelos J Giamarellos-Bourboulis, Ewan C Goligher, Michelle Ng Gong, Eleni Karakike, Vincent X Liu, Nuttha Lumlertgul, John C Marshall, David K Menon, Nuala J Meyer, Elizabeth S Munroe, Sheila Nainan Myatra, Marlies Ostermann, Hallie C Prescott, Adrienne G Randolph, Edward J Schenck, Christopher W Seymour, Manu Shankar-Hari, Mervyn Singer, Marry R Smit, Aiko Tanaka, Fabio S Taccone, B Taylor Thompson, Lisa K Torres, Tom van der Poll, Jean-Louis Vincent, Carolyn S Calfee
From ICU Syndromes to ICU Subphenotypes: Consensus Report and Recommendations for Developing Precision Medicine in the ICU. American journal of respiratory and critical care medicine 210 (2) (2024)
Puja Mehta, Romit J Samanta, Katherine Wick, Rebecca C Coll, Thea Mawhinney, Patrick G McAleavey, Andrew J Boyle, John Conlon, Manu Shankar-Hari, Angela Rogers, Carolyn S Calfee, Michael A Matthay, Charlotte Summers, Rachel Clare Chambers, Daniel Francis McAuley, Cecilia M O'Kane
Elevated ferritin, mediated by IL-18 is associated with systemic inflammation and mortality in acute respiratory distress syndrome (ARDS). Thorax 79 (3) (2024)
Hallie C Prescott, David A Harrison, Kathryn M Rowan, Manu Shankar-Hari, Hannah Wunsch
Temporal Trends in Mortality of Critically Ill Patients with Sepsis in the United Kingdom, 1988-2019. American journal of respiratory and critical care medicine 209 (5) (2024)
David Benjamin Antcliffe, Yuxin Mi, Shalini Santhakumaran, Katie L Burnham, A Toby Prevost, Josie K Ward, Timothy J Marshall, Claire Bradley, Farah Al-Beidh, Paula Hutton, Stuart McKechnie, Emma E Davenport, Charles J Hinds, Cecilia M O'Kane, Daniel Francis McAuley, Manu Shankar-Hari, Anthony C Gordon, Julian C Knight
Patient stratification using plasma cytokines and their regulators in sepsis: relationship to outcomes, treatment effect and leucocyte transcriptomic subphenotypes. Thorax 79 (6) (2024)
Anthony C Gordon, Narges Alipanah-Lechner, Lieuwe D Bos, Jose Dianti, Janet Victoria Diaz, Simon Finfer, Tomoko Fujii, Evangelos J Giamarellos-Bourboulis, Ewan C Goligher, Michelle Ng Gong, Eleni Karakike, Vincent Liu, Nuttha Lumlertgul, John C Marshall, David K Menon, Nuala J Meyer, Elizabeth S Munroe, Sheila N Myatra, Marlies Ostermann, Hallie C Prescott, Adrienne G Randolph, Edward J Schenck, Christopher W Seymour, Manu Shankar-Hari, Mervyn Singer, Marry R Smit, Aiko Tanaka, Fabio Silvio Taccone, B Taylor Thompson, Lisa K Torres, Tom Van der Poll, Jean-Louis Vincent, Carolyn S Calfee
From ICU Syndromes to ICU Subphenotypes: Consensus Report and Recommendations For Developing Precision Medicine in ICU. American journal of respiratory and critical care medicine (2024)
Harsita Patel, Michael J Carter, Heather R Jackson, Oliver Powell, Matthew Fish, Manuela Terranova-Barberio, Filomena Spada, Nedyalko Petrov, Paul Wellman, Sarah Darnell, Sobia Mustafa, Katrina Todd, Cynthia Bishop, Jonathan M Cohen, Julia Kenny, Sarah van den Berg, Thomas Sun, Francesca Davis, Aislinn Jennings, Emma Timms, Jessica Thomas, Maggie Nyirendra, Samuel J Nichols, Leire Estamiana Elorieta, Giselle D'Souza, Victoria J Wright, Tisham De, Dominic Habgood-Coote, Padmanabhan Ramnarayan, Pierre Tissères, Elizabeth Whittaker, Jethro Herberg, Aubrey J Cunnington, Myrsini Kaforou, Richard J Ellis, Michael H Malim, Shane M Tibby, Manu Shankar-Hari, Michael Levin, null null
Shared neutrophil and T cell dysfunction is accompanied by a distinct interferon signature during severe febrile illnesses in children. Nature communications 15 (1) (2024)
Puja Mehta, Romit J Samanta, Katherine Wick, Rebecca C Coll, Thea Mawhinney, Patrick G McAleavey, Andrew J Boyle, John Conlon, Manu Shankar-Hari, Angela Rogers, Carolyn S Calfee, Michael A Matthay, Charlotte Summers, Rachel Clare Chambers, Daniel Francis McAuley, Cecilia M O'Kane
Elevated ferritin, mediated by IL-18 is associated with systemic inflammation and mortality in acute respiratory distress syndrome (ARDS). Thorax (2024)
Anthony C Gordon, Narges Alipanah-Lechner, Lieuwe D Bos, Jose Dianti, Janet Victoria Diaz, Simon Finfer, Tomoko Fujii, Evangelos J Giamarellos-Bourboulis, Ewan C Goligher, Michelle Ng Gong, Eleni Karakike, Vincent Liu, Nuttha Lumlertgul, John C Marshall, David K Menon, Nuala J Meyer, Elizabeth S Munroe, Sheila N Myatra, Marlies Ostermann, Hallie C Prescott, Adrienne G Randolph, Edward J Schenck, Christopher W Seymour, Manu Shankar-Hari, Mervyn Singer, Marry R Smit, Aiko Tanaka, Fabio Silvio Taccone, B Taylor Thompson, Lisa K Torres, Tom Van der Poll, Jean-Louis Vincent, Carolyn S Calfee
From ICU Syndromes to ICU Subphenotypes: Consensus Report and Recommendations For Developing Precision Medicine in ICU. American journal of respiratory and critical care medicine (2024)
Anthony C Gordon, Narges Alipanah-Lechner, Lieuwe D J Bos, Jose Dianti, Janet V Diaz, Simon R Finfer, Tomoko Fujii, Evangelos J Giamarellos-Bourboulis, Ewan C Goligher, Michelle Ng Gong, Eleni Karakike, Vincent X Liu, Nuttha Lumlertgul, John C Marshall, David K Menon, Nuala J Meyer, Elizabeth S Munroe, Sheila Nainan Myatra, Marlies Ostermann, Hallie C Prescott, Adrienne G Randolph, Edward J Schenck, Christopher W Seymour, Manu Shankar-Hari, Mervyn Singer, Marry R Smit, Aiko Tanaka, Fabio S Taccone, B Taylor Thompson, Lisa K Torres, Tom van der Poll, Jean-Louis Vincent, Carolyn S Calfee
From ICU Syndromes to ICU Subphenotypes: Consensus Report and Recommendations for Developing Precision Medicine in the ICU. American journal of respiratory and critical care medicine 210 (2) (2024)
Hallie C Prescott, David A Harrison, Kathryn M Rowan, Manu Shankar-Hari, Hannah Wunsch
Temporal Trends in Mortality of Critically Ill Patients with Sepsis in the United Kingdom, 1988-2019. American journal of respiratory and critical care medicine 209 (5) (2024)
John Cafferkey, Manu Shankar-Hari
Informative Subtyping of Patients with Sepsis. Seminars in respiratory and critical care medicine 45 (4) (2024)
Hallie C Prescott, David A Harrison, Kathryn M Rowan, Manu Shankar-Hari, Hannah Wunsch
Temporal Trends in Mortality of Critically Ill Patients with Sepsis in the United Kingdom, 1988-2019. American journal of respiratory and critical care medicine (2024)
Anthony C Gordon, Narges Alipanah-Lechner, Lieuwe D J Bos, Jose Dianti, Janet V Diaz, Simon R Finfer, Tomoko Fujii, Evangelos J Giamarellos-Bourboulis, Ewan C Goligher, Michelle Ng Gong, Eleni Karakike, Vincent X Liu, Nuttha Lumlertgul, John C Marshall, David K Menon, Nuala J Meyer, Elizabeth S Munroe, Sheila Nainan Myatra, Marlies Ostermann, Hallie C Prescott, Adrienne G Randolph, Edward J Schenck, Christopher W Seymour, Manu Shankar-Hari, Mervyn Singer, Marry R Smit, Aiko Tanaka, Fabio S Taccone, B Taylor Thompson, Lisa K Torres, Tom van der Poll, Jean-Louis Vincent, Carolyn S Calfee
From ICU Syndromes to ICU Subphenotypes: Consensus Report and Recommendations for Developing Precision Medicine in the ICU. American journal of respiratory and critical care medicine 210 (2) (2024)
John Cafferkey, Manu Shankar-Hari
Informative Subtyping of Patients with Sepsis. Seminars in respiratory and critical care medicine 45 (4) (2024)
David Benjamin Antcliffe, Yuxin Mi, Shalini Santhakumaran, Katie L Burnham, A Toby Prevost, Josie K Ward, Timothy J Marshall, Claire Bradley, Farah Al-Beidh, Paula Hutton, Stuart McKechnie, Emma E Davenport, Charles J Hinds, Cecilia M O'Kane, Daniel Francis McAuley, Manu Shankar-Hari, Anthony C Gordon, Julian C Knight
Patient stratification using plasma cytokines and their regulators in sepsis: relationship to outcomes, treatment effect and leucocyte transcriptomic subphenotypes. Thorax 79 (6) (2024)
David Benjamin Antcliffe, Yuxin Mi, Shalini Santhakumaran, Katie L Burnham, A Toby Prevost, Josie K Ward, Timothy J Marshall, Claire Bradley, Farah Al-Beidh, Paula Hutton, Stuart McKechnie, Emma E Davenport, Charles J Hinds, Cecilia M O'Kane, Daniel Francis McAuley, Manu Shankar-Hari, Anthony C Gordon, Julian C Knight
Patient stratification using plasma cytokines and their regulators in sepsis: relationship to outcomes, treatment effect and leucocyte transcriptomic subphenotypes. Thorax (2024)
Puja Mehta, Romit J Samanta, Katherine Wick, Rebecca C Coll, Thea Mawhinney, Patrick G McAleavey, Andrew J Boyle, John Conlon, Manu Shankar-Hari, Angela Rogers, Carolyn S Calfee, Michael A Matthay, Charlotte Summers, Rachel Clare Chambers, Daniel Francis McAuley, Cecilia M O'Kane
Elevated ferritin, mediated by IL-18 is associated with systemic inflammation and mortality in acute respiratory distress syndrome (ARDS). Thorax 79 (3) (2024)
David Benjamin Antcliffe, Yuxin Mi, Shalini Santhakumaran, Katie L Burnham, A Toby Prevost, Josie K Ward, Timothy J Marshall, Claire Bradley, Farah Al-Beidh, Paula Hutton, Stuart McKechnie, Emma E Davenport, Charles J Hinds, Cecilia M O'Kane, Daniel Francis McAuley, Manu Shankar-Hari, Anthony C Gordon, Julian C Knight
Patient stratification using plasma cytokines and their regulators in sepsis: relationship to outcomes, treatment effect and leucocyte transcriptomic subphenotypes. Thorax 79 (6) (2024)
Puja Mehta, Romit J Samanta, Katherine Wick, Rebecca C Coll, Thea Mawhinney, Patrick G McAleavey, Andrew J Boyle, John Conlon, Manu Shankar-Hari, Angela Rogers, Carolyn S Calfee, Michael A Matthay, Charlotte Summers, Rachel Clare Chambers, Daniel Francis McAuley, Cecilia M O'Kane
Elevated ferritin, mediated by IL-18 is associated with systemic inflammation and mortality in acute respiratory distress syndrome (ARDS). Thorax 79 (3) (2024)
Omer Elneima, John R Hurst, Carlos Echevarria, Jennifer Kathleen Quint, Samantha Walker, Salman Siddiqui, Petr Novotny, Paul E Pfeffer, Jeremy S Brown, Manu Shankar-Hari, Hamish Joseph Cameron McAuley, Olivia C Leavy, Aarti Shikotra, Amisha Singapuri, Marco Sereno, Matthew Richardson, Ruth M Saunders, Victoria C Harris, Linzy Houchen-Wolloff, Neil J Greening, Ewen M Harrison, Annemarie B Docherty, Nazir I Lone, James D Chalmers, Ling-Pei Ho, Alex Robert Horsley, Michael Marks, Krisnah Poinasamy, Betty Raman, Rachael Andrea Evans, Louise V Wain, Aziz Sheikh, Chris E Brightling, Anthony De Soyza, Liam G Heaney
Long-term impact of COVID-19 hospitalisation among individuals with pre-existing airway diseases in the UK: a multicentre, longitudinal cohort study - PHOSP-COVID. ERJ open research 10 (4) (2024)
Puja Mehta, Romit J Samanta, Katherine Wick, Rebecca C Coll, Thea Mawhinney, Patrick G McAleavey, Andrew J Boyle, John Conlon, Manu Shankar-Hari, Angela Rogers, Carolyn S Calfee, Michael A Matthay, Charlotte Summers, Rachel Clare Chambers, Daniel Francis McAuley, Cecilia M O'Kane
Elevated ferritin, mediated by IL-18 is associated with systemic inflammation and mortality in acute respiratory distress syndrome (ARDS). Thorax 79 (3) (2024)
Anthony C Gordon, Narges Alipanah-Lechner, Lieuwe D Bos, Jose Dianti, Janet Victoria Diaz, Simon Finfer, Tomoko Fujii, Evangelos J Giamarellos-Bourboulis, Ewan C Goligher, Michelle Ng Gong, Eleni Karakike, Vincent Liu, Nuttha Lumlertgul, John C Marshall, David K Menon, Nuala J Meyer, Elizabeth S Munroe, Sheila N Myatra, Marlies Ostermann, Hallie C Prescott, Adrienne G Randolph, Edward J Schenck, Christopher W Seymour, Manu Shankar-Hari, Mervyn Singer, Marry R Smit, Aiko Tanaka, Fabio Silvio Taccone, B Taylor Thompson, Lisa K Torres, Tom Van der Poll, Jean-Louis Vincent, Carolyn S Calfee
From ICU Syndromes to ICU Subphenotypes: Consensus Report and Recommendations For Developing Precision Medicine in ICU. American journal of respiratory and critical care medicine (2024)
Anthony C Gordon, Narges Alipanah-Lechner, Lieuwe D Bos, Jose Dianti, Janet Victoria Diaz, Simon Finfer, Tomoko Fujii, Evangelos J Giamarellos-Bourboulis, Ewan C Goligher, Michelle Ng Gong, Eleni Karakike, Vincent Liu, Nuttha Lumlertgul, John C Marshall, David K Menon, Nuala J Meyer, Elizabeth S Munroe, Sheila N Myatra, Marlies Ostermann, Hallie C Prescott, Adrienne G Randolph, Edward J Schenck, Christopher W Seymour, Manu Shankar-Hari, Mervyn Singer, Marry R Smit, Aiko Tanaka, Fabio Silvio Taccone, B Taylor Thompson, Lisa K Torres, Tom Van der Poll, Jean-Louis Vincent, Carolyn S Calfee
From ICU Syndromes to ICU Subphenotypes: Consensus Report and Recommendations For Developing Precision Medicine in ICU. American journal of respiratory and critical care medicine (2024)
John Cafferkey, Manu Shankar-Hari
Informative Subtyping of Patients with Sepsis. Seminars in respiratory and critical care medicine (2024)
Anthony C Gordon, Narges Alipanah-Lechner, Lieuwe D Bos, Jose Dianti, Janet Victoria Diaz, Simon Finfer, Tomoko Fujii, Evangelos J Giamarellos-Bourboulis, Ewan C Goligher, Michelle Ng Gong, Eleni Karakike, Vincent Liu, Nuttha Lumlertgul, John C Marshall, David K Menon, Nuala J Meyer, Elizabeth S Munroe, Sheila N Myatra, Marlies Ostermann, Hallie C Prescott, Adrienne G Randolph, Edward J Schenck, Christopher W Seymour, Manu Shankar-Hari, Mervyn Singer, Marry R Smit, Aiko Tanaka, Fabio Silvio Taccone, B Taylor Thompson, Lisa K Torres, Tom Van der Poll, Jean-Louis Vincent, Carolyn S Calfee
From ICU Syndromes to ICU Subphenotypes: Consensus Report and Recommendations For Developing Precision Medicine in ICU. American journal of respiratory and critical care medicine (2024)
David Benjamin Antcliffe, Yuxin Mi, Shalini Santhakumaran, Katie L Burnham, A Toby Prevost, Josie K Ward, Timothy J Marshall, Claire Bradley, Farah Al-Beidh, Paula Hutton, Stuart McKechnie, Emma E Davenport, Charles J Hinds, Cecilia M O'Kane, Daniel Francis McAuley, Manu Shankar-Hari, Anthony C Gordon, Julian C Knight
Patient stratification using plasma cytokines and their regulators in sepsis: relationship to outcomes, treatment effect and leucocyte transcriptomic subphenotypes. Thorax 79 (6) (2024)
Omer Elneima, John R Hurst, Carlos Echevarria, Jennifer Kathleen Quint, Samantha Walker, Salman Siddiqui, Petr Novotny, Paul E Pfeffer, Jeremy S Brown, Manu Shankar-Hari, Hamish Joseph Cameron McAuley, Olivia C Leavy, Aarti Shikotra, Amisha Singapuri, Marco Sereno, Matthew Richardson, Ruth M Saunders, Victoria C Harris, Linzy Houchen-Wolloff, Neil J Greening, Ewen M Harrison, Annemarie B Docherty, Nazir I Lone, James D Chalmers, Ling-Pei Ho, Alex Robert Horsley, Michael Marks, Krisnah Poinasamy, Betty Raman, Rachael Andrea Evans, Louise V Wain, Aziz Sheikh, Chris E Brightling, Anthony De Soyza, Liam G Heaney
Long-term impact of COVID-19 hospitalisation among individuals with pre-existing airway diseases in the UK: a multicentre, longitudinal cohort study - PHOSP-COVID. ERJ open research 10 (4) (2024)
Erola Pairo-Castineira, Konrad Rawlik, Andrew D Bretherick, Ting Qi, Yang Wu, Isar Nassiri, Glenn A McConkey, Marie Zechner, Lucija Klarić, Fiona Griffiths, Wilna Oosthuyzen, Athanasios Kousathanas, Anne Richmond, Jonathan Millar, Clark D Russell, Tomas Malinauskas, Ryan S Thwaites, Kirstie Morrice, Sean Keating, David Maslove, Alistair Nichol, Malcolm Gracie Semple, Julian Knight, Manu Shankar-Hari, Charlotte Summers, Charles J Hinds, Peter Horby, Lowell Ling, Daniel Francis McAuley, Hugh E Montgomery, Peter J M Openshaw, Colin Begg, Timothy Walsh, Albert Tenesa, Carlos Flores, José A Riancho, Augusto Rojas-Martinez, Pablo Lapunzina, null null, null null, null null, null null, Jian Yang, Chris Paul Ponting, James F Wilson, Veronique Vitart, Malak Abedalthagafi, Andre D Luchessi, Esteban J Parra, Raquel Cruz, Angel Carracedo, Angie Fawkes, Lee Murphy, Kathryn M Rowan, Alexandre C Pereira, Andrew Law, Benjamin P Fairfax, Sara Clohisey Hendry, John Kenneth Baillie
GWAS and meta-analysis identifies 49 genetic variants underlying critical COVID-19. Nature (2023)
Elizabeth S Munroe, Robert C Hyzy, Matthew W Semler, Manu Shankar-Hari, Paul Jeffrey Young, Fernando Godinho Zampieri, Hallie C Prescott
Evolving Management Practices for Early Sepsis-induced Hypoperfusion: A Narrative Review. American journal of respiratory and critical care medicine (2023)
Puja Mehta, Romit J Samanta, Katherine Wick, Rebecca C Coll, Thea Mawhinney, Patrick G McAleavey, Andrew J Boyle, John Conlon, Manu Shankar-Hari, Angela Rogers, Carolyn S Calfee, Michael A Matthay, Charlotte Summers, Rachel Clare Chambers, Daniel Francis McAuley, Cecilia M O'Kane
Elevated ferritin, mediated by IL-18 is associated with systemic inflammation and mortality in acute respiratory distress syndrome (ARDS). Thorax (2023)
Bryan S Blette, Anders Granholm, Fan Li, Manu Shankar-Hari, Theis Lange, Marie Warrer Munch, Morten Hylander Møller, Anders Perner, Michael O Harhay
Causal Bayesian machine learning to assess treatment effect heterogeneity by dexamethasone dose for patients with COVID-19 and severe hypoxemia. Scientific reports 13 (1) (2023)
Bryan S Blette, Anders Granholm, Fan Li, Manu Shankar-Hari, Theis Lange, Marie Warrer Munch, Morten Hylander Møller, Anders Perner, Michael O Harhay
Causal Bayesian machine learning to assess treatment effect heterogeneity by dexamethasone dose for patients with COVID-19 and severe hypoxemia. Scientific reports 13 (1) (2023)
Bryan S Blette, Anders Granholm, Fan Li, Manu Shankar-Hari, Theis Lange, Marie Warrer Munch, Morten Hylander Møller, Anders Perner, Michael O Harhay
Causal Bayesian machine learning to assess treatment effect heterogeneity by dexamethasone dose for patients with COVID-19 and severe hypoxemia. Scientific reports 13 (1) (2023)
Ellen A Gorman, Jennifer Rynne, Hannah J Gardiner, Anthony J Rostron, Jonathan Bannard-Smith, Andrew M Bentley, David Brealey, Christina Campbell, Gerard Curley, Mike Clarke, Ahilanadan Dushianthan, Phillip Hopkins, Colette Jackson, Kallirroi Kefela, Anna D Krasnodembskaya, John Gerard Laffey, Cliona McDowell, Margaret McFarland, Jamie McFerran, Peter McGuigan, Gavin D Perkins, Jonathan Silversides, Jon Smythe, Jacqui Thompson, William S Tunnicliffe, Ingeborg Dm Welters, Laura Amado-Rodríguez, Guillermo Albaiceta, Barry Williams, Manu Shankar-Hari, Daniel F McAuley, Cecilia M O'Kane
Repair of Acute Respiratory Distress Syndrome in COVID-19 by Stromal Cells (REALIST-COVID Trial): A Multicentre, Randomised, Controlled Trial. American journal of respiratory and critical care medicine (2023)
Erola Pairo-Castineira, Konrad Rawlik, Andrew D Bretherick, Ting Qi, Yang Wu, Isar Nassiri, Glenn A McConkey, Marie Zechner, Lucija Klarić, Fiona Griffiths, Wilna Oosthuyzen, Athanasios Kousathanas, Anne Richmond, Jonathan Millar, Clark D Russell, Tomas Malinauskas, Ryan S Thwaites, Kirstie Morrice, Sean Keating, David Maslove, Alistair Nichol, Malcolm Gracie Semple, Julian Knight, Manu Shankar-Hari, Charlotte Summers, Charles J Hinds, Peter Horby, Lowell Ling, Daniel Francis McAuley, Hugh E Montgomery, Peter J M Openshaw, Colin Begg, Timothy Walsh, Albert Tenesa, Carlos Flores, José A Riancho, Augusto Rojas-Martinez, Pablo Lapunzina, null null, null null, null null, null null, Jian Yang, Chris Paul Ponting, James F Wilson, Veronique Vitart, Malak Abedalthagafi, Andre D Luchessi, Esteban J Parra, Raquel Cruz, Angel Carracedo, Angie Fawkes, Lee Murphy, Kathryn M Rowan, Alexandre C Pereira, Andrew Law, Benjamin P Fairfax, Sara Clohisey Hendry, John Kenneth Baillie
Author Correction: GWAS and meta-analysis identifies 49 genetic variants underlying critical COVID-19. Nature (2023)
Rohit Saha, Tài Pham, Pratik Sinha, Manoj V Maddali, Giacomo Bellani, Eddy Fan, Charlotte Summers, Abdel Douiri, Gordon D Rubenfeld, Carolyn S Calfee, John Gerard Laffey, Daniel Francis McAuley, Manu Shankar-Hari, null null
Estimating the attributable fraction of mortality from acute respiratory distress syndrome to inform enrichment in future randomised clinical trials. Thorax (2023)
Thomas M A Wilkinson, Anthony De Soyza, Miles W Carroll, James D Chalmers, Michael G Crooks, Gareth Griffiths, Manu Shankar-Hari, Ling-Pei Ho, Alex Robert Horsley, Chris Kell, Beatriz Lara Gallego, Biswa Mishra, Rachel Moate, Clive Page, Hitesh Pandya, Jason Raw, Fred Reid, Dinesh Saralaya, Ian C Scott, Salman Siddiqui, Andy Ustianowski, Natalie van Zuydam, Ashley Woodcock, Dave Singh
A randomised phase 2a study to investigate the effects of blocking interleukin-33 with tozorakimab in patients hospitalised with COVID-19: ACCORD-2. ERJ open research 9 (5) (2023)
null null, Thomas E Hills, Elizabeth Lorenzi, Lindsay R Berry, Murali Shyamsundar, Farah Al-Beidh, Djillali Annane, Yaseen Arabi, Diptesh Aryal, Carly Au, Abigail Beane, Zahra Bhimani, Marc Bonten, Charlotte Ann Bradbury, Frank M Brunkhorst, Aidan Burrell, Meredith Buxton, Carolyn S Calfee, Maurizio Cecconi, Allen C Cheng, Matthew Edward Cove, Michelle A Detry, Lise J Estcourt, Mark Fitzgerald, Ewan C Goligher, Herman Goossens, Cameron Green, Rashan Haniffa, David A Harrison, Madiha Hashmi, Alisa M Higgins, David T Huang, Nao Ichihara, Deva Jayakumar, Peter S Kruger, François Lamontagne, Lamprini Lampro, Patrick R Lawler, John C Marshall, Alexina J Mason, Anna McGlothlin, Shay McGuinness, Zoe K McQuilten, Bryan J McVerry, Paul R Mouncey, Srinivas Murthy, Matthew D Neal, Alistair D Nichol, Cecilia M O'Kane, Rachael L Parke, Jane C Parker, Ebenezer Rabindrarajan, Luis Felipe Reyes, Kathryn M Rowan, Hiroki Saito, Marlene Santos, Christina T Saunders, Christopher W Seymour, Manu Shankar-Hari, Pratik Sinha, B Taylor Thompson, Alexis F Turgeon, Anne M Turner, Frank van van de Veerdonk, Sebastian Weis, Ian S Young, Ryan Zarychanski, Roger J Lewis, Colin J McArthur, Derek C Angus, Scott M Berry, Lennie P G Derde, Steve A Webb, Anthony C Gordon, Daniel Francis McAuley
Simvastatin in Critically Ill Patients with Covid-19. The New England journal of medicine (2023)
Bryan S Blette, Anders Granholm, Fan Li, Manu Shankar-Hari, Theis Lange, Marie Warrer Munch, Morten Hylander Møller, Anders Perner, Michael O Harhay
Causal Bayesian machine learning to assess treatment effect heterogeneity by dexamethasone dose for patients with COVID-19 and severe hypoxemia. Scientific reports 13 (1) (2023)
Bryan S Blette, Anders Granholm, Fan Li, Manu Shankar-Hari, Theis Lange, Marie Warrer Munch, Morten Hylander Møller, Anders Perner, Michael O Harhay
Causal Bayesian machine learning to assess treatment effect heterogeneity by dexamethasone dose for patients with COVID-19 and severe hypoxemia. Scientific reports 13 (1) (2023)
Kate L Arkless, Dingxin Pan, Manu Shankar-Hari, Richard T Amison, Clive Peter Page, Khondaker Miraz Rahman, Simon C Pitchford
Stimulation of platelet P2Y 1 receptors by different endogenous nucleotides leads to functional selectivity via biased signalling. British journal of pharmacology (2023)
Bryan S Blette, Anders Granholm, Fan Li, Manu Shankar-Hari, Theis Lange, Marie Warrer Munch, Morten Hylander Møller, Anders Perner, Michael O Harhay
Causal Bayesian machine learning to assess treatment effect heterogeneity by dexamethasone dose for patients with COVID-19 and severe hypoxemia. Scientific reports 13 (1) (2023)
Kate L Arkless, Dingxin Pan, Manu Shankar-Hari, Richard T Amison, Clive Peter Page, Khondaker Miraz Rahman, Simon C Pitchford
Stimulation of platelet P2Y 1 receptors by different endogenous nucleotides leads to functional selectivity via biased signalling. British journal of pharmacology (2023)
Jonathan Scott, Loredana Trevi, Hannah McNeil, Tom Ewen, Phil Mawson, David McDonald, Andrew Filby, Ranjit Lall, Katie Booth, Gert Boschman, Vesna Melkebeek, Gavin Perkins, Ronan McMullan, Daniel Francis McAuley, Iain J McCullagh, Timothy Walsh, Anthony Rostron, Manu Shankar-Hari, Paul Dark, A John Simpson, Andrew Conway Morris, Thomas P Hellyer
Role of immunosuppression in an antibiotic stewardship intervention and its association with clinical outcomes and antibiotic use: protocol for an observational study (RISC-sepsis). BMJ open 12 (12) (2022)
David M Maslove, Benjamin M Tang, Manu Shankar-Hari, Patrick R Lawler, Derek C Angus, John Kenneth Baillie, Rebecca M Baron, Michael Bauer, Timothy G Buchman, Carolyn S Calfee, Claudia C Dos Santos, Evangelos J Giamarellos-Bourboulis, Anthony C Gordon, John A Kellum, Julian C Knight, Aleksandra Leligdowicz, Daniel Francis McAuley, Anthony S McLean, David K Menon, Nuala J Meyer, Lyle L Moldawer, Kiran Reddy, John P Reilly, James A Russell, Jonathan E Sevransky, Christopher W Seymour, Nathan I Shapiro, Mervyn Singer, Charlotte Summers, Timothy E Sweeney, B Taylor Thompson, Tom van der Poll, Balasubramanian Venkatesh, Keith R Walley, Timothy S Walsh, Lorraine B Ware, Hector R Wong, Zsolt E Zador, John C Marshall
Redefining critical illness. Nature medicine 28 (6) (2022)
M Fish, J Rynne, A Jennings, C Lam, A A Lamikanra, J Ratcliff, S Cellone-Trevelin, E Timms, J Jiriha, I Tosi, R Pramanik, P Simmonds, S Seth, J Williams, A C Gordon, J Knight, D J Smith, J Whalley, D Harrison, K Rowan, H Harvala, P Klenerman, L Estcourt, D K Menon, D Roberts, Manu Shankar-Hari, null null
Coronavirus disease 2019 subphenotypes and differential treatment response to convalescent plasma in critically ill adults: secondary analyses of a randomized clinical trial. Intensive care medicine 48 (11) (2022)
Vera B M Peters, Nishkantha Arulkumaran, Miranda J Melis, Charlotte Gaupp, Thierry Roger, Manu Shankar-Hari, Mervyn Singer
Butyrate Supplementation Exacerbates Myocardial and Immune Cell Mitochondrial Dysfunction in a Rat Model of Faecal Peritonitis. Life (Basel, Switzerland) 12 (12) (2022)
Jonathan Scott, Loredana Trevi, Hannah McNeil, Tom Ewen, Phil Mawson, David McDonald, Andrew Filby, Ranjit Lall, Katie Booth, Gert Boschman, Vesna Melkebeek, Gavin Perkins, Ronan McMullan, Daniel Francis McAuley, Iain J McCullagh, Timothy Walsh, Anthony Rostron, Manu Shankar-Hari, Paul Dark, A John Simpson, Andrew Conway Morris, Thomas P Hellyer
Role of immunosuppression in an antibiotic stewardship intervention and its association with clinical outcomes and antibiotic use: protocol for an observational study (RISC-sepsis). BMJ open 12 (12) (2022)
Jonathan Scott, Loredana Trevi, Hannah McNeil, Tom Ewen, Phil Mawson, David McDonald, Andrew Filby, Ranjit Lall, Katie Booth, Gert Boschman, Vesna Melkebeek, Gavin Perkins, Ronan McMullan, Daniel Francis McAuley, Iain J McCullagh, Timothy Walsh, Anthony Rostron, Manu Shankar-Hari, Paul Dark, A John Simpson, Andrew Conway Morris, Thomas P Hellyer
Role of immunosuppression in an antibiotic stewardship intervention and its association with clinical outcomes and antibiotic use: protocol for an observational study (RISC-sepsis). BMJ open 12 (12) (2022)
Martina Patone, Winnie Xue Mei, Lahiru Handunnetthi, Sharon Dixon, Francesco Zaccardi, Manu Shankar-Hari, Peter Watkinson, Kamlesh Khunti, Anthony Harnden, Carol A C Coupland, Keith M Channon, Nicholas L Mills, Aziz Sheikh, Julia Hippisley-Cox
Risk of Myocarditis After Sequential Doses of COVID-19 Vaccine and SARS-CoV-2 Infection by Age and Sex. Circulation 146 (10) (2022)
Jeremy Ratcliff, Farah Al-Beidh, Sagida Bibi, David G Bonsall, Sue Ann Costa Clemens, Lise Estcourt, Amy Evans, Matthew Fish, Pedro M Folegatti, Anthony C Gordon, Cecilia Jay, Aislinn Jennings, Emma Laing, Teresa Lambe, George MacIntyre-Cockett, David Menon, Paul R Mouncey, Dung Nguyen, Andrew J Pollard, Maheshi N Ramasamy, David J Roberts, Kathryn M Rowan, Jennifer Rynne, Manu Shankar-Hari, Sarah Williams, Heli Harvala, Tanya Golubchik, Peter Simmonds, null null
Highly Sensitive Lineage Discrimination of SARS-CoV-2 Variants through Allele-Specific Probe PCR. Journal of clinical microbiology 60 (4) (2022)
Erin E Gaughan, Tom M Quinn, Andrew Mills, Annya M Bruce, Jean Antonelli, Alison MacKinnon, Vassilios Aslanis, Feng Li, Richard O'Connor, Cecilia Boz, Ross Mills, Philip Emanuel, Matthew Burgess, Giulia Rinaldi, Asta Valanciute, Bethany Mills, Emma Scholefield, Gareth Hardisty, Emily Gwyer Findlay, Richard A Parker, John Norrie, James W Dear, Ahsan R Akram, Oliver Koch, Kate Templeton, David H Dockrell, Timothy S Walsh, Stephen Partridge, Duncan Humphries, Jie Wang-Jairaj, Robert J Slack, Hans Schambye, De Phung, Lise Gravelle, Bertil Lindmark, Manu Shankar-Hari, Nikhil Hirani, Tariq Sethi, Kevin Dhaliwal
An Inhaled Galectin-3 Inhibitor in COVID-19 Pneumonitis (DEFINE): A Phase Ib/IIa Randomised Controlled Trial. American journal of respiratory and critical care medicine (2022)
Bang Zheng, Luke Daines, Qing Han, John R Hurst, Paul Pfeffer, Manu Shankar-Hari, Omer Elneima, Samantha Walker, Jeremy S Brown, Salman Siddiqui, Jennifer Kathleen Quint, Christopher E Brightling, Rachael Andrea Evans, Louise V Wain, Liam G Heaney, Aziz Sheikh
Prevalence, risk factors and treatments for post-COVID-19 breathlessness: a systematic review and meta-analysis. European respiratory review : an official journal of the European Respiratory Society 31 (166) (2022)
Frank L van de Veerdonk, Evangelos J Giamarellos-Bourboulis, Peter Pickkers, Lennie P G Derde, Helen Leavis, Reinout van Crevel, Job J Engel, W Joost Wiersinga, Alexander P J Vlaar, Manu Shankar-Hari, Tom van der Poll, Marc Bonten, Derek C Angus, Jos W M van der Meer, Mihai M Netea
A guide to immunotherapy for COVID-19. Nature medicine 28 (1) (2022)
Vera B M Peters, Nishkantha Arulkumaran, Miranda J Melis, Charlotte Gaupp, Thierry Roger, Manu Shankar-Hari, Mervyn Singer
Butyrate Supplementation Exacerbates Myocardial and Immune Cell Mitochondrial Dysfunction in a Rat Model of Faecal Peritonitis. Life (Basel, Switzerland) 12 (12) (2022)
Jonathan Scott, Loredana Trevi, Hannah McNeil, Tom Ewen, Phil Mawson, David McDonald, Andrew Filby, Ranjit Lall, Katie Booth, Gert Boschman, Vesna Melkebeek, Gavin Perkins, Ronan McMullan, Daniel Francis McAuley, Iain J McCullagh, Timothy Walsh, Anthony Rostron, Manu Shankar-Hari, Paul Dark, A John Simpson, Andrew Conway Morris, Thomas P Hellyer
Role of immunosuppression in an antibiotic stewardship intervention and its association with clinical outcomes and antibiotic use: protocol for an observational study (RISC-sepsis). BMJ open 12 (12) (2022)
Athanasios Kousathanas, Erola Pairo-Castineira, Konrad Rawlik, Alex Stuckey, Christopher A Odhams, Susan Walker, Clark D Russell, Tomas Malinauskas, Yang Wu, Jonathan Millar, Xia Shen, Katherine S Elliott, Fiona Griffiths, Wilna Oosthuyzen, Kirstie Morrice, Sean Keating, Bo Wang, Daniel Rhodes, Lucija Klarić, Marie Zechner, Nicholas J Parkinson, Afshan Siddiq, Peter Goddard, Sally Donovan, David Maslove, Alistair Nichol, Malcolm Gracie Semple, Tala Zainy, Fiona Maleady-Crowe, Linda Todd, Shahla Salehi, Julian C Knight, Greg Elgar, Georgia Chan, Prabhu Arumugam, Christine Patch, Augusto Rendon, David Bentley, Clare Kingsley, Jack A Kosmicki, Julie E Horowitz, Aris Baras, Gonçalo R Abecasis, Manuel A R Ferreira, Anne Justice, Tooraj Mirshahi, Matthew Oetjens, Daniel James Rader, Marylyn DeRiggi Ritchie, Anurag Verma, Tom A Fowler, Manu Shankar-Hari, Charlotte Summers, Charles J Hinds, Peter Horby, Lowell Ling, Daniel Francis McAuley, Hugh E Montgomery, Peter J M Openshaw, Paul Elliott, Timothy Walsh, Albert Tenesa, null null, null null, null null, Angie Fawkes, Lee Murphy, Kathryn M Rowan, Chris Paul Ponting, Veronique Vitart, James F Wilson, Jian Yang, Andrew D Bretherick, Richard H Scott, Sara Clohisey Hendry, Loukas Moutsianas, Andrew Law, Mark J Caulfield, John Kenneth Baillie
Whole-genome sequencing reveals host factors underlying critical COVID-19. Nature 607 (7917) (2022)
Vera B M Peters, Nishkantha Arulkumaran, Miranda J Melis, Charlotte Gaupp, Thierry Roger, Manu Shankar-Hari, Mervyn Singer
Butyrate Supplementation Exacerbates Myocardial and Immune Cell Mitochondrial Dysfunction in a Rat Model of Faecal Peritonitis. Life (Basel, Switzerland) 12 (12) (2022)
Vera B M Peters, Nishkantha Arulkumaran, Miranda J Melis, Charlotte Gaupp, Thierry Roger, Manu Shankar-Hari, Mervyn Singer
Butyrate Supplementation Exacerbates Myocardial and Immune Cell Mitochondrial Dysfunction in a Rat Model of Faecal Peritonitis. Life (Basel, Switzerland) 12 (12) (2022)
Vera B M Peters, Nishkantha Arulkumaran, Miranda J Melis, Charlotte Gaupp, Thierry Roger, Manu Shankar-Hari, Mervyn Singer
Butyrate Supplementation Exacerbates Myocardial and Immune Cell Mitochondrial Dysfunction in a Rat Model of Faecal Peritonitis. Life (Basel, Switzerland) 12 (12) (2022)
Andrew Conway Morris, Jennifer Rynne, Manu Shankar-Hari
Compartmentalisation of immune responses in critical illness: does it matter? Intensive care medicine 48 (11) (2022)
Tom Moore, Rojony Hossain, Katie J Doores, Manu Shankar-Hari, David J Fear
SARS-CoV-2-Specific Memory B Cell Responses Are Maintained After Recovery from Natural Infection and Postvaccination. Viral immunology 35 (6) (2022)
Andrew Conway Morris, Katharina Kohler, Manu Shankar-Hari
ARDS subphenotypes: searching for Rorschach among the roentgenograms? Thorax (2021)
Kate C Tatham, Manu Shankar-Hari, Yaseen M Arabi
The REMDACTA trial: do interleukin receptor antagonists provide additional benefit in COVID-19? Intensive care medicine 47 (11) (2021)
Michael Bauer, Manu Shankar-Hari, Daniel O Thomas-Rüddel, Reinhard Wetzker
Towards an ecological definition of sepsis: a viewpoint. Intensive care medicine experimental 9 (1) (2021)
null null, Anthony C Gordon, Paul R Mouncey, Farah Al-Beidh, Kathryn M Rowan, Alistair D Nichol, Yaseen M Arabi, Djillali Annane, Abigail Beane, Wilma van Bentum-Puijk, Lindsay R Berry, Zahra Bhimani, Marc J M Bonten, Charlotte Ann Bradbury, Frank M Brunkhorst, Adrian Buzgau, Allen C Cheng, Michelle A Detry, Eamon J Duffy, Lise J Estcourt, Mark Fitzgerald, Herman Goossens, Rashan Haniffa, Alisa M Higgins, Thomas E Hills, Christopher M Horvat, Francois Lamontagne, Patrick R Lawler, Helen L Leavis, Kelsey M Linstrum, Edward Litton, Elizabeth Lorenzi, John C Marshall, Florian B Mayr, Daniel F McAuley, Anna McGlothlin, Shay P McGuinness, Bryan J McVerry, Stephanie K Montgomery, Susan C Morpeth, Srinivas Murthy, Katrina Orr, Rachael L Parke, Jane C Parker, Asad E Patanwala, Ville Pettilä, Emma Rademaker, Marlene S Santos, Christina T Saunders, Christopher W Seymour, Manu Shankar-Hari, Wendy I Sligl, Alexis F Turgeon, Anne M Turner, Frank L van de Veerdonk, Ryan Zarychanski, Cameron Green, Roger J Lewis, Derek C Angus, Colin J McArthur, Scott Berry, Steve A Webb, Lennie P G Derde
Interleukin-6 Receptor Antagonists in Critically Ill Patients with Covid-19. The New England journal of medicine 384 (16) (2021)
Jeremy Ratcliff, Dung Nguyen, Matthew Fish, Jennifer Rynne, Aislinn Jennings, Sarah Williams, Farah Al-Beidh, David Bonsall, Amy Evans, Tanya Golubchik, Anthony C Gordon, Abigail Lamikanra, Pat Tsang, Nick A Ciccone, Ullrich Leuscher, Wendy Slack, Emma Laing, Paul R Mouncey, Sheba Ziyenge, Marta Oliveira, Rutger Ploeg, Kathryn M Rowan, Manu Shankar-Hari, David J Roberts, David K Menon, Lise Estcourt, Peter Simmonds, Heli Harvala, null null
Virological Characterization of Critically Ill Patients With COVID-19 in the United Kingdom: Interactions of Viral Load, Antibody Status, and B.1.1.7 Infection. The Journal of infectious diseases 224 (4) (2021)
Martina Patone, Winnie Xue Mei, Lahiru Handunnetthi, Sharon Dixon, Francesco Zaccardi, Manu Shankar-Hari, Peter J Watkinson, Kamlesh Khunti, Anthony Harnden, Carol A C Coupland, Keith M Channon, Nicholas L Mills, Aziz Sheikh, Julia Hippisley-Cox
Risks of myocarditis, pericarditis, and cardiac arrhythmias associated with COVID-19 vaccination or SARS-CoV-2 infection. Nature medicine 28 (2) (2021)
Liane Dupont, Luke B Snell, Carl Graham, Jeffrey Seow, Blair Merrick, Thomas Lechmere, Thomas J A Maguire, Sadie R Hallett, Suzanne Pickering, Themoula Charalampous, Adela Alcolea-Medina, Isabella Huettner, Jose M Jimenez-Guardeño, Sam Acors, Nathalia Almeida, Daniel Cox, Ruth E Dickenson, Rui Pedro Galao, Neophytos Kouphou, Marie Jose Lista, Ana Maria Ortega-Prieto, Harry D Wilson, Helena Winstone, Cassandra Fairhead, Jia Zhe Su, Gaia Nebbia, Rahul Batra, Stuart J D Neil, Manu Shankar-Hari, Jonathan D Edgeworth, Michael H Malim, Katie J Doores
Neutralizing antibody activity in convalescent sera from infection in humans with SARS-CoV-2 and variants of concern. Nature microbiology 6 (11) (2021)
Lieuwe D J Bos, Antonio Artigas, Jean-Michel Constantin, Laura A Hagens, Nanon Heijnen, John Gerard Laffey, Nuala Meyer, Laurent Papazian, Lara Pisani, Marcus J Schultz, Manu Shankar-Hari, Marry R Smit, Charlotte Summers, Lorraine B Ware, Raffaele Scala, Carolyn S Calfee
Precision medicine in acute respiratory distress syndrome: workshop report and recommendations for future research. European respiratory review : an official journal of the European Respiratory Society 30 (159) (2021)
Clemens Gutmann, Kaloyan Takov, Sean A Burnap, Bhawana Singh, Hashim Ali, Konstantinos Theofilatos, Ella Reed, Maria Hasman, Adam Nabeebaccus, Matthew Fish, Mark Jw McPhail, Kevin O'Gallagher, Lukas Emanuel Schmidt, Christian Cassel, Marieke Rienks, Xiaoke Yin, Georg Auzinger, Salvatore Napoli, Salma F Mujib, Francesca Trovato, Barnaby Sanderson, Blair Merrick, Umar Niazi, Mansoor Saqi, Konstantina Dimitrakopoulou, Rafael Fernandez-Leiro, Silke Doris Braun, Romy Kronstein-Wiedemann, Katie J Doores, Jonathan D Edgeworth, Ajay M Shah, Stefan R Bornstein, Torsten Tonn, Adrian C Hayday, Mauro Giacca, Manu Shankar-Hari, Manuel Mayr
SARS-CoV-2 RNAemia and proteomic trajectories inform prognostication in COVID-19 patients admitted to intensive care. Nature communications 12 (1) (2021)
James C Doidge, Doug William Gould, Paloma Ferrando-Vivas, Paul R Mouncey, Karen Thomas, Manu Shankar-Hari, David A Harrison, Kathryn M Rowan
Trends in Intensive Care for Patients with COVID-19 in England, Wales, and Northern Ireland. American journal of respiratory and critical care medicine 203 (5) (2021)
null null, null null, null null, Patrick R Lawler, Ewan C Goligher, Jeffrey S Berger, Matthew D Neal, Bryan J McVerry, Jose C Nicolau, Michelle N Gong, Marc Carrier, Robert S Rosenson, Harmony R Reynolds, Alexis F Turgeon, Jorge Escobedo, David T Huang, Charlotte Ann Bradbury, Brett L Houston, Lucy Z Kornblith, Anand Kumar, Susan R Kahn, Mary Cushman, Zoe McQuilten, Arthur S Slutsky, Keri S Kim, Anthony C Gordon, Bridget-Anne Kirwan, Maria M Brooks, Alisa M Higgins, Roger J Lewis, Elizabeth Lorenzi, Scott M Berry, Lindsay R Berry, Aaron W Aday, Farah Al-Beidh, Djillali Annane, Yaseen M Arabi, Diptesh Aryal, Lisa Baumann Kreuziger, Abigail Beane, Zahra Bhimani, Shailesh Bihari, Henny H Billett, Lindsay Bond, Marc Bonten, Frank Brunkhorst, Meredith Buxton, Adrian Buzgau, Lana A Castellucci, Sweta Chekuri, Jen-Ting Chen, Allen C Cheng, Tamta Chkhikvadze, Benjamin Coiffard, Todd W Costantini, Sophie de Brouwer, Lennie P G Derde, Michelle A Detry, Abhijit Duggal, Vladimír Džavík, Mark B Effron, Lise J Estcourt, Brendan M Everett, Dean A Fergusson, Mark Fitzgerald, Robert A Fowler, Jean P Galanaud, Benjamin T Galen, Sheetal Gandotra, Sebastian García-Madrona, Timothy D Girard, Lucas Colombo Godoy, Andrew L Goodman, Herman Goossens, Cameron Green, Yonatan Y Greenstein, Peter L Gross, Naomi M Hamburg, Rashan Haniffa, George Hanna, Nicholas Hanna, Sheila M Hegde, Carolyn M Hendrickson, R Duncan Hite, Alexander A Hindenburg, Aluko A Hope, James M Horowitz, Christopher M Horvat, Kristin Hudock, Beverley J Hunt, Mansoor Husain, Robert C Hyzy, Vivek N Iyer, Jeffrey R Jacobson, Devachandran Jayakumar, Norma M Keller, Akram Khan, Yuri Kim, Andrei L Kindzelski, Andrew J King, M Margaret Knudson, Aaron E Kornblith, Vidya Krishnan, Matthew E Kutcher, Michael A Laffan, Francois Lamontagne, Grégoire Le Gal, Christine M Leeper, Eric S Leifer, George Lim, Felipe Gallego Lima, Kelsey Linstrum, Edward Litton, Jose Lopez-Sendon, José Luis López-Sendon Moreno, Sylvain A Lother, Saurabh Malhotra, Miguel Marcos, Andréa Saud Marinez, John C Marshall, Nicole Marten, Michael A Matthay, Daniel F McAuley, Emily G McDonald, Anna McGlothlin, Shay P McGuinness, Saskia Middeldorp, Stephanie K Montgomery, Steven C Moore, Raquel Morillo Guerrero, Paul R Mouncey, Srinivas Murthy, Girish B Nair, Rahul Nair, Alistair D Nichol, Brenda Nunez-Garcia, Ambarish Pandey, Pauline K Park, Rachael L Parke, Jane C Parker, Sam Parnia, Jonathan D Paul, Yessica S Pérez González, Mauricio Pompilio, Matthew E Prekker, John G Quigley, Natalia S Rost, Kathryn Rowan, Fernanda O Santos, Marlene Santos, Mayler Olombrada Santos, Lewis Satterwhite, Christina T Saunders, Roger E G Schutgens, Christopher W Seymour, Deborah M Siegal, Delcio G Silva, Manu Shankar-Hari, John P Sheehan, Aneesh B Singhal, Dayna Solvason, Simon J Stanworth, Tobias Tritschler, Anne M Turner, Wilma van Bentum-Puijk, Frank L van de Veerdonk, Sean van Diepen, Gloria Vazquez-Grande, Lana Wahid, Vanessa Wareham, Bryan J Wells, R Jay Widmer, Jennifer G Wilson, Eugene Yuriditsky, Fernando Godinho Zampieri, Derek C Angus, Colin J McArthur, Steven A Webb, Michael E Farkouh, Judith S Hochman, Ryan Zarychanski
Therapeutic Anticoagulation with Heparin in Noncritically Ill Patients with Covid-19. The New England journal of medicine 385 (9) (2021)
Fernando Godinho Zampieri, Jonathan Dale Casey, Manu Shankar-Hari, Frank E Harrell, Michael O Harhay
Using Bayesian Methods to Augment the Interpretation of Critical Care Trials. An Overview of Theory and Example Reanalysis of the Alveolar Recruitment for Acute Respiratory Distress Syndrome Trial. American journal of respiratory and critical care medicine 203 (5) (2021)
Alvin Richards-Belle, Izabella Orzechowska, James Doidge, Karen Thomas, David A Harrison, Abby Koelewyn, Michael D Christian, Manu Shankar-Hari, Kathryn M Rowan, Doug William Gould
Critical care outcomes, for the first 200 patients with confirmed COVID-19, in England, Wales and Northern Ireland: A report from the ICNARC Case Mix Programme. Journal of the Intensive Care Society 22 (4) (2020)
Adam G Laing, Anna Lorenc, Irene Del Molino Del Barrio, Abhishek Das, Matthew Fish, Leticia Monin, Miguel Muñoz-Ruiz, Duncan R McKenzie, Thomas S Hayday, Isaac Francos-Quijorna, Shraddha Kamdar, Magdalene Joseph, Daniel Davies, Richard Davis, Aislinn Jennings, Iva Zlatareva, Pierre Vantourout, Yin Wu, Vasiliki Sofra, Florencia Cano, Maria Greco, Efstathios Theodoridis, Joshua D Freedman, Sarah Gee, Julie Nuo En Chan, Sarah Ryan, Eva Bugallo-Blanco, Pärt Peterson, Kai Kisand, Liis Haljasmägi, Loubna Chadli, Philippe Moingeon, Lauren Martinez, Blair Merrick, Karen Bisnauthsing, Kate Brooks, Mohammad A A Ibrahim, Jeremy C Mason, Federico Lopez Gomez, Kola Babalola, Sultan Abdul-Jawad, John Cason, Christine Mant, Jeffrey Seow, Carl Graham, Katie J Doores, Francesca Di Rosa, Jonathan Edgeworth, Manu Shankar-Hari, Adrian C Hayday
A dynamic COVID-19 immune signature includes associations with poor prognosis. Nature medicine 26 (10) (2020)
Michael J Carter, Matthew Fish, Aislinn Jennings, Katie J Doores, Paul Wellman, Jeffrey Seow, Sam Acors, Carl Graham, Emma Timms, Julia Kenny, Stuart Neil, Michael H Malim, Shane M Tibby, Manu Shankar-Hari
Peripheral immunophenotypes in children with multisystem inflammatory syndrome associated with SARS-CoV-2 infection. Nature medicine 26 (11) (2020)
Morten Hylander Möller, Manu Shankar-Hari, Waleed Alhazzani
Use of Hydrocortisone Based on Plasma Biomarkers in Patients with Septic Shock: Another One Bites the Dust? American journal of respiratory and critical care medicine 202 (5) (2020)
Manu Shankar-Hari, Lise Estcourt, Heli Harvala, David Roberts, David K Menon, null null
Convalescent plasma to treat critically ill patients with COVID-19: framing the need for randomised clinical trials. Critical care (London, England) 24 (1) (2020)
Alvin Richards-Belle, Izabella Orzechowska, Doug William Gould, Karen Thomas, James C Doidge, Paul R Mouncey, Michael D Christian, Manu Shankar-Hari, David A Harrison, Kathryn M Rowan, null null
COVID-19 in critical care: epidemiology of the first epidemic wave across England, Wales and Northern Ireland. Intensive care medicine 46 (11) (2020)
Jeffrey Seow, Carl Graham, Blair Merrick, Sam Acors, Suzanne Pickering, Kathryn J A Steel, Oliver Hemmings, Aoife O'Byrne, Neophytos Kouphou, Rui Pedro Galao, Gilberto Betancor, Harry D Wilson, Adrian W Signell, Helena Winstone, Claire Kerridge, Isabella Huettner, Jose M Jimenez-Guardeño, Maria Jose Lista, Nigel J Temperton, Luke Blagdon Snell, Karen Bisnauthsing, Amelia Moore, Adrian Green, Lauren Martinez, Brielle Stokes, Johanna Honey, Alba Izquierdo-Barras, Gill Arbane, Amita Patel, Mark Kia Ik Tan, Lorcan O'Connell, Geraldine O'Hara, Eithne MacMahon, Sam Douthwaite, Gaia Nebbia, Rahul Batra, Rocio Martinez-Nunez, Manu Shankar-Hari, Jonathan D Edgeworth, Stuart J D Neil, Michael H Malim, Katie J Doores
Longitudinal observation and decline of neutralizing antibody responses in the three months following SARS-CoV-2 infection in humans. Nature microbiology 5 (12) (2020)
Erola Pairo-Castineira, Sara Clohisey, Lucija Klarić, Andrew D Bretherick, Konrad Rawlik, Dorota Pasko, Susan Walker, Nick Parkinson, Max Head Fourman, Clark D Russell, James Furniss, Anne Richmond, Elvina Gountouna, Nicola Wrobel, David Harrison, Bo Wang, Yang Wu, Alison Meynert, Fiona Griffiths, Wilna Oosthuyzen, Athanasios Kousathanas, Loukas Moutsianas, Zhijian Yang, Ranran Zhai, Chenqing Zheng, Graeme Grimes, Rupert C L Beale, Jonathan Millar, Barbara Shih, Sean Keating, Marie Zechner, Christopher S Haley, David J Porteous, Caroline Hayward, Jian Yang, Julian C Knight, Charlotte Summers, Manu Shankar-Hari, Paul Klenerman, Lance C W Turtle, Antonia Ho, Shona C Moore, Charles J Hinds, Peter Horby, Alistair Nichol, David Maslove, Lowell Ling, Daniel Francis McAuley, Hugh E Montgomery, Timothy Walsh, Alexandre C Pereira, Alessandra Renieri, null null, null null, null null, null null, null null, null null, Xia Shen, Chris Paul Ponting, Angie Fawkes, Albert Tenesa, Mark J Caulfield, Richard Scott, Kathryn M Rowan, Lee Murphy, Peter J M Openshaw, Malcolm Gracie Semple, Andrew Law, Veronique Vitart, James F Wilson, John Kenneth Baillie
Genetic mechanisms of critical illness in COVID-19. Nature 591 (7848) (2020)
Matthew Fish, Kate Arkless, Aislinn Jennings, Julie Wilson, Michael J Carter, Gill Arbane, Sara Campos, Neus Novellas, Rianne Wester, Nedyalko Petrov, Umar Niazi, Barnaby Sanderson, Richard Ellis, Mansoor Saqi, Jo Spencer, Mervyn Singer, Rocio T Martinez-Nunez, Simon Pitchford, Chad M Swanson, Manu Shankar-Hari
Cellular and molecular mechanisms of IMMunE dysfunction and Recovery from SEpsis-related critical illness in adults: An observational cohort study (IMMERSE) protocol paper. Journal of the Intensive Care Society 23 (3) (2020)
Manu Shankar-Hari, Rohit Saha, Julie Wilson, Hallie C Prescott, David Harrison, Kathryn Rowan, Gordon D Rubenfeld, Neill K J Adhikari
Rate and risk factors for rehospitalisation in sepsis survivors: systematic review and meta-analysis. Intensive care medicine 46 (4) (2020)
Aitana Braza-Boïls, Temo Barwari, Clemens Gutmann, Mark R Thomas, Heather M Judge, Abhishek Joshi, Raimund Pechlaner, Manu Shankar-Hari, Ramzi A Ajjan, Ian Sabroe, Robert F Storey, Manuel Mayr
Circulating MicroRNA Levels Indicate Platelet and Leukocyte Activation in Endotoxemia Despite Platelet P2Y12 Inhibition. International journal of molecular sciences 21 (8) (2020)
Shalini Santhakumaran, Anthony Gordon, A Toby Prevost, Cecilia O'Kane, Daniel F McAuley, Manu Shankar-Hari
Heterogeneity of treatment effect by baseline risk of mortality in critically ill patients: re-analysis of three recent sepsis and ARDS randomised controlled trials. Critical care (London, England) 23 (1) (2019)
Manu Shankar-Hari, Matthew Fish, Elie Azoulay
Should we consider blocking the inhibitory immune checkpoint molecules for treating T cell exhaustion in sepsis? Intensive care medicine 46 (1) (2019)
Phebe Ekregbesi, Manu Shankar-Hari, Christian Bottomley, Eleanor M Riley, Jason P Mooney
Relationship between Anaemia, Haemolysis, Inflammation and Haem Oxygenase-1 at Admission with Sepsis: a pilot study. Scientific reports 8 (1) (2018)
Manu Shankar-Hari, E Fan, N D Ferguson
Acute respiratory distress syndrome (ARDS) phenotyping. Intensive care medicine 45 (4) (2018)
Manu Shankar-Hari, Martin Bruun Madsen, Alexis F Turgeon
Immunoglobulins and sepsis. Intensive care medicine 44 (11) (2018)
Manu Shankar-Hari, Deepankar Datta, Julie Wilson, Valentina Assi, Jacqueline Stephen, Christopher J Weir, Jillian Rennie, Jean Antonelli, Anthony Bateman, Jennifer M Felton, Noel Warner, Kevin Judge, Jim Keenan, Alice Wang, Tony Burpee, Alun K Brown, Sion M Lewis, Tracey Mare, Alistair I Roy, John Wright, Gillian Hulme, Ian Dimmick, Alasdair Gray, Adriano G Rossi, A John Simpson, Andrew Conway Morris, Timothy S Walsh
Early PREdiction of sepsis using leukocyte surface biomarkers: the ExPRES-sepsis cohort study. Intensive care medicine 44 (11) (2018)
Manu Shankar-Hari, Daniel F McAuley
Acute Respiratory Distress Syndrome Phenotypes and Identifying Treatable Traits. The Dawn of Personalized Medicine for ARDS. American journal of respiratory and critical care medicine 195 (3) (2017)
Manu Shankar-Hari
How could we enhance translation of sepsis immunology to inform immunomodulation trials in sepsis? Critical care (London, England) 21 (1) (2017)
Joel Meyer, Manu Shankar-Hari
Protocolised early goal-directed therapy in patients with sepsis/septic shock does not result in improved survival compared with usual care with less invasive resuscitation strategies. Evidence-based medicine 22 (6) (2017)
Manu Shankar-Hari, Daniel F McAuley
Divide and conquer: identifying acute respiratory distress syndrome subphenotypes. Thorax 72 (10) (2017)

Manu Shankar-Hari.css-eqlu8i{font-size:small;padding-left:4px;} (M Shankar-Hari)

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Manu Shankar-Hari (M Shankar-Hari)