Mauro Giacca (M Giacca)

Scopus Author ID ResearcherID ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 50

Top Venues

Nature cardiovascular research

Nature communications

Cardiovascular research

The Journal of pathology

King's College London

University of Genoa (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

King's College London Jan 01 2019

United Kingdom

Professor of Cardiovascular Sciences :: School of Cardiovascular Medicine & Sciences

University of Trieste

Italy

Full Professor :: Department of Medical, Surgical and Health Sciences

International Centre for Genetic Engineering and Biotechnology (ICGEB) - Jun 30 2019

Italy

Director-General

International Centre for Genetic Engineering and Biotechnology (ICGEB)

Italy

Director :: Trieste Component

Scuola Normale Superiore

Italy

Associate Professor :: Classe di Scienze

Scuola Normale Superiore

Italy

Director, Molecular Biology Laboratory

International Centre for Genetic Engineering and Biotechnology (ICGEB)

Italy

Senior Scientist and Group Leader :: Molecular Medicine

International Centre for Genetic Engineering and Biotechnology (ICGEB)

Italy

Staff Scientist :: Molecular Biology

Education History

University of Genoa

Italy

PHD

Publications

Francesca Maremonti, Wulf Tonnus, Shubhangi Gavali, Stefan Bornstein, Ajay Shah, Mauro Giacca, Andreas Linkermann
Ferroptosis-based advanced therapies as treatment approaches for metabolic and cardiovascular diseases. Cell death and differentiation 31 (9) (2024)
Mauro Giacca
SARS-CoV-2 infection boosts inflammation in atherosclerotic plaques. Nature cardiovascular research 2 (11) (2024)
Mahmoud Salama Ahmed, Ngoc Uyen Nhi Nguyen, Yuji Nakada, Ching-Cheng Hsu, Ayman Farag, Nicholas T Lam, Ping Wang, Suwannee Thet, Ivan Menendez-Montes, Waleed M Elhelaly, Xi Lou, Ilaria Secco, Mateusz Tomczyk, Lorena Zentilin, Jimin Pei, Miao Cui, Matthieu Dos Santos, Xiaoye Liu, Yan Liu, David Zaha, Gregory Walcott, Diana R Tomchick, Chao Xing, Cheng Cheng Zhang, Nick V Grishin, Mauro Giacca, Jianyi Jay Zhang, Hesham A Sadek
Identification of FDA-approved drugs that induce heart regeneration in mammals. Nature cardiovascular research 3 (3) (2024)
Mahmoud Salama Ahmed, Ngoc Uyen Nhi Nguyen, Yuji Nakada, Ching-Cheng Hsu, Ayman Farag, Nicholas T Lam, Ping Wang, Suwannee Thet, Ivan Menendez-Montes, Waleed M Elhelaly, Xi Lou, Ilaria Secco, Mateusz Tomczyk, Lorena Zentilin, Jimin Pei, Miao Cui, Matthieu Dos Santos, Xiaoye Liu, Yan Liu, David Zaha, Gregory Walcott, Diana R Tomchick, Chao Xing, Cheng Cheng Zhang, Nick V Grishin, Mauro Giacca, Jianyi Jay Zhang, Hesham A Sadek
Identification of FDA-approved drugs that induce heart regeneration in mammals. Nature cardiovascular research 3 (3) (2024)
Francesca Maremonti, Wulf Tonnus, Shubhangi Gavali, Stefan Bornstein, Ajay Shah, Mauro Giacca, Andreas Linkermann
Ferroptosis-based advanced therapies as treatment approaches for metabolic and cardiovascular diseases. Cell death and differentiation (2024)
Mauro Giacca
SARS-CoV-2 infection boosts inflammation in atherosclerotic plaques. Nature cardiovascular research 2 (11) (2024)
Mahmoud Salama Ahmed, Ngoc Uyen Nhi Nguyen, Yuji Nakada, Ching-Cheng Hsu, Ayman Farag, Nicholas T Lam, Ping Wang, Suwannee Thet, Ivan Menendez-Montes, Waleed M Elhelaly, Xi Lou, Ilaria Secco, Mateusz Tomczyk, Lorena Zentilin, Jimin Pei, Miao Cui, Matthieu Dos Santos, Xiaoye Liu, Yan Liu, David Zaha, Gregory Walcott, Diana R Tomchick, Chao Xing, Cheng Cheng Zhang, Nick V Grishin, Mauro Giacca, Jianyi Jay Zhang, Hesham A Sadek
Identification of FDA-approved drugs that induce heart regeneration in mammals. Nature cardiovascular research 3 (3) (2024)
Mahmoud Salama Ahmed, Ngoc Uyen Nhi Nguyen, Yuji Nakada, Ching-Cheng Hsu, Ayman Farag, Nicholas T Lam, Ping Wang, Suwannee Thet, Ivan Menendez-Montes, Waleed M Elhelaly, Xi Lou, Ilaria Secco, Mateusz Tomczyk, Lorena Zentilin, Jimin Pei, Miao Cui, Matthieu Dos Santos, Xiaoye Liu, Yan Liu, David Zaha, Gregory Walcott, Diana R Tomchick, Chao Xing, Cheng Cheng Zhang, Nick V Grishin, Mauro Giacca, Jianyi Jay Zhang, Hesham A Sadek
Identification of FDA-approved drugs that induce heart regeneration in mammals. Nature cardiovascular research 3 (3) (2024)
Rossana Bussani, Lorena Zentilin, Ricardo Correa, Andrea Colliva, Furio Silvestri, Serena Zacchigna, Chiara Collesi, Mauro Giacca
Persistent SARS-CoV-2 infection in patients seemingly recovered from COVID-19. The Journal of pathology 259 (3) (2023)
Rossana Bussani, Lorena Zentilin, Ricardo Correa, Andrea Colliva, Furio Silvestri, Serena Zacchigna, Chiara Collesi, Mauro Giacca
Persistent SARS-CoV-2 infection in patients seemingly recovered from COVID-19. The Journal of pathology 259 (3) (2023)
Eirini Kyriakopoulou, Danielle Versteeg, Hesther de Ruiter, Ilaria Perini, Fitzwilliam Seibertz, Yannic Döring, Lorena Zentilin, Hoyee Tsui, Sebastiaan J van Kampen, Malte Tiburcy, Tim Meyer, Niels Voigt, van J Peter Tintelen, Wolfram H Zimmermann, Mauro Giacca, Eva van Rooij
Therapeutic efficacy of AAV-mediated restoration of PKP2 in arrhythmogenic cardiomyopathy. Nature cardiovascular research 2 (12) (2023)
Stefania Canè, Roza Maria Barouni, Marina Fabbi, John W Cuozzo, Giulio Fracasso, Annalisa Adamo, Stefano Ugel, Rosalinda Trovato, Francesco De Sanctis, Mauro Giacca, Rita Teresa Lawlor, Aldo Scarpa, Borislav Rusev, Gabriella Lionetto, Salvatore Paiella, Roberto Salvia, Claudio Bassi, Susanna Mandruzzato, Silvano Ferrini, Vincenzo Bronte
Neutralization of NET-associated human ARG1 enhances cancer immunotherapy. Science translational medicine 15 (687) (2023)
Rossana Bussani, Lorena Zentilin, Ricardo Correa, Andrea Colliva, Furio Silvestri, Serena Zacchigna, Chiara Collesi, Mauro Giacca
Persistent SARS-CoV-2 infection in patients seemingly recovered from COVID-19. The Journal of pathology 259 (3) (2023)
Tamara P Martin, Eilidh A MacDonald, Ashley Bradley, Holly Watson, Priyanka Saxena, Eva A Rog-Zielinska, Anmar Raheem, Simon Fisher, Ali Ali Mohamed Elbassioni, Ohood Almuzaini, Catriona Booth, Morna Campbell, Alex Riddell, Pawel Herzyk, Karen Blyth, Colin Nixon, Lorena Zentilin, Colin Berry, Thomas Braun, Mauro Giacca, Martin W McBride, Stuart A Nicklin, Ewan R Cameron, Christopher M Loughrey
RNA interference or small molecule inhibition of Runx1 in the border zone prevents cardiac contractile dysfunction following myocardial infarction. Cardiovascular research (2023)
Mauro Giacca
Fulfilling the Promise of RNA Therapies for Cardiac Repair and Regeneration. Stem cells translational medicine (2023)
Stefania Canè, Roza Maria Barouni, Marina Fabbi, John W Cuozzo, Giulio Fracasso, Annalisa Adamo, Stefano Ugel, Rosalinda Trovato, Francesco De Sanctis, Mauro Giacca, Rita Teresa Lawlor, Aldo Scarpa, Borislav Rusev, Gabriella Lionetto, Salvatore Paiella, Roberto Salvia, Claudio Bassi, Susanna Mandruzzato, Silvano Ferrini, Vincenzo Bronte
Neutralization of NET-associated human ARG1 enhances cancer immunotherapy. Science translational medicine 15 (687) (2023)
Rossana Bussani, Lorena Zentilin, Ricardo Correa, Andrea Colliva, Furio Silvestri, Serena Zacchigna, Chiara Collesi, Mauro Giacca
Persistent SARS-CoV-2 infection in patients seemingly recovered from COVID-19. The Journal of pathology (2023)
Eirini Kyriakopoulou, Danielle Versteeg, Hesther de Ruiter, Ilaria Perini, Fitzwilliam Seibertz, Yannic Döring, Lorena Zentilin, Hoyee Tsui, Sebastiaan J van Kampen, Malte Tiburcy, Tim Meyer, Niels Voigt, van J Peter Tintelen, Wolfram H Zimmermann, Mauro Giacca, Eva van Rooij
Therapeutic efficacy of AAV-mediated restoration of PKP2 in arrhythmogenic cardiomyopathy. Nature cardiovascular research 2 (12) (2023)
Roman Roy, Antonio Cannata, Mohammad Al-Agil, Emma Ferone, Antonio Jordan, Brian To-Dang, Matthew Sadler, Aamir Shamsi, Mohammad Albarjas, Susan Piper, Mauro Giacca, Ajay M Shah, Theresa A McDonagh, Daniel I Bromage, Paul A Scott
Diagnostic accuracy, clinical characteristics, and prognostic differences of patients with acute myocarditis according to inclusion criteria. European heart journal. Quality of care & clinical outcomes (2023)
Roberto Dinami, Luca Pompili, Eleonora Petti, Manuela Porru, Carmen D'Angelo, Serena Di Vito, Angela Rizzo, Virginia Campani, Giuseppe De Rosa, Alejandra Bruna, Violeta Serra, Miguel Mano, Mauro Giacca, Carlo Leonetti, Gennaro Ciliberto, Madalena Tarsounas, Antonella Stoppacciaro, Stefan Schoeftner, Annamaria Biroccio
MiR-182-3p targets TRF2 and impairs tumor growth of triple-negative breast cancer. EMBO molecular medicine (2022)
Giulia Ruozi, Francesca Bortolotti, Antonio Mura, Mateusz Tomczyk, Antonella Falcione, Valentina Martinelli, Simone Vodret, Luca Braga, Matteo Dal Ferro, Antonio Cannata, Lorena Zentilin, Gianfranco Sinagra, Serena Zacchigna, Mauro Giacca
Cardioprotective factors against myocardial infarction selected in vivo from an AAV secretome library. Science translational medicine 14 (660) (2022)
Cornelis J Boogerd, Grégory P A Lacraz, Abel Vertesy, Sebastiaan Johannes van Kampen, Ilaria Perini, Hesther de Ruiter, Danielle Versteeg, Andreas Brodehl, Petra van der Kraak, Mauro Giacca, Nicolaas de Jonge, Jan Philipp Junker, Alexander van Oudernaarden, Aryan Vink, Eva van Rooij
Spatial transcriptomics unveils ZBTB11 as a regulator of cardiomyocyte degeneration in arrhythmogenic cardiomyopathy. Cardiovascular research (2022)
Monika M Gladka, Mauro Giacca
Scientists on the Spot: Re-awakening the heart's regenerative capacity. Cardiovascular research 117 (6) (2022)
Ajay M Shah, Mauro Giacca
Small non-coding RNA therapeutics for cardiovascular disease. European heart journal 43 (43) (2022)
Nicola Pianca, Francesca Sacchi, Kfir Baruch Umansky, Maila Chirivì, Luisa Iommarini, Silvia Da Pra, Valentina Papa, Chiara Bongiovanni, Carmen Miano, Francesca Pontis, Luca Braga, Riccardo Tassinari, Elvira Pantano, Rahul Shastry Patnala, Martina Mazzeschi, Giovanna Cenacchi, Anna Maria Porcelli, Mattia Lauriola, Carlo Ventura, Mauro Giacca, Roberto Rizzi, Eldad Tzahor, Gabriele D'Uva
Glucocorticoid receptor antagonization propels endogenous cardiomyocyte proliferation and cardiac regeneration. Nature cardiovascular research 1 (7) (2022)
Mauro Giacca
Gene editing for cardiomyopathy takes a step forward. Cardiovascular research (2022)
Michele Ciccarelli, Dana K Dawson, Inês Falcão Pires, Mauro Giacca, Nazha Hamdani, Stéphane Heymans, Astrid M Hooghiemstra, Annebet Leeuwis, Dorien Hermkens, Carlo Gabriele Tocchetti, Jolanda van der Velden, Serena Zacchigna, Thomas Thum
Reciprocal organ interactions during heart failure: a position paper from the ESC Working Group on Myocardial Function. Cardiovascular research 117 (12) (2022)
Mauro Giacca, Ajay M Shah
The pathological maelstrom of COVID-19 and cardiovascular disease. Nature cardiovascular research 1 (3) (2022)
Andrea Raso, Ellen Dirkx, Vasco Sampaio-Pinto, Hamid El Azzouzi, Ryan John A Cubero, Daniel W Sorensen, Lara Ottaviani, Servé Olieslagers, Manon M H Huibers, Roel de Weger, Sailay Siddiqi, Silvia Moimas, Consuelo Torrini, Lorena Zentillin, Luca Braga, Diana Santos Nascimento, Paula A da Costa Martins, Jop H van Berlo, Serena Zacchigna, Mauro Giacca, Leon J De Windt
Author Correction: A microRNA program regulates the balance between cardiomyocyte hyperplasia and hypertrophy and stimulates cardiac regeneration. Nature communications 13 (1) (2022)
Alice Rossi, Luisa Galla, Chiara Gomiero, Lorena Zentilin, Mauro Giacca, Valentina Giorgio, Tito Cali, Tullio Pozzan, Elisa Greotti, Paola Pizzo
Calcium Signaling and Mitochondrial Function in Presenilin 2 Knock-Out Mice: Looking for Any Loss-of-Function Phenotype Related to Alzheimer's Disease. Cells 10 (2) (2021)
Clemens Gutmann, Kaloyan Takov, Sean A Burnap, Bhawana Singh, Hashim Ali, Konstantinos Theofilatos, Ella Reed, Maria Hasman, Adam Nabeebaccus, Matthew Fish, Mark Jw McPhail, Kevin O'Gallagher, Lukas Emanuel Schmidt, Christian Cassel, Marieke Rienks, Xiaoke Yin, Georg Auzinger, Salvatore Napoli, Salma F Mujib, Francesca Trovato, Barnaby Sanderson, Blair Merrick, Umar Niazi, Mansoor Saqi, Konstantina Dimitrakopoulou, Rafael Fernandez-Leiro, Silke Doris Braun, Romy Kronstein-Wiedemann, Katie J Doores, Jonathan D Edgeworth, Ajay M Shah, Stefan R Bornstein, Torsten Tonn, Adrian C Hayday, Mauro Giacca, Manu Shankar-Hari, Manuel Mayr
SARS-CoV-2 RNAemia and proteomic trajectories inform prognostication in COVID-19 patients admitted to intensive care. Nature communications 12 (1) (2021)
Luca Braga, Hashim Ali, Ilaria Secco, Elena Chiavacci, Guilherme Neves, Daniel H Goldhill, Rebecca Penn, Jose M Jimenez-Guardeño, Ana Maria Ortega-Prieto, Rossana Bussani, Antonio Cannata, Giorgia Rizzari, Chiara Collesi, Edoardo Schneider, Daniele Arosio, Ajay M Shah, Wendy S Barclay, Michael H Malim, Juan Burrone, Mauro Giacca
Drugs that inhibit TMEM16 proteins block SARS-CoV-2 spike-induced syncytia. Nature 594 (7861) (2021)
Andrea Raso, Ellen Dirkx, Vasco Sampaio-Pinto, Hamid El Azzouzi, Ryan John A Cubero, Daniel W Sorensen, Lara Ottaviani, Servé Olieslagers, Manon M H Huibers, Roel de Weger, Sailay Siddiqi, Silvia Moimas, Consuelo Torrini, Lorena Zentillin, Luca Braga, Diana Santos Nascimento, Paula A da Costa Martins, Jop H van Berlo, Serena Zacchigna, Mauro Giacca, Leon J De Windt
A microRNA program regulates the balance between cardiomyocyte hyperplasia and hypertrophy and stimulates cardiac regeneration. Nature communications 12 (1) (2021)
Thomas P Peacock, Daniel H Goldhill, Jie Zhou, Laury Baillon, Rebecca Frise, Olivia C Swann, Ruthiran Kugathasan, Rebecca Penn, Jonathan C Brown, Raul Y Sanchez-David, Luca Braga, Maia Kavanagh Williamson, Jack A Hassard, Ecco Staller, Brian Hanley, Michael Osborn, Mauro Giacca, Andrew D Davidson, David A Matthews, Wendy S Barclay
The furin cleavage site in the SARS-CoV-2 spike protein is required for transmission in ferrets. Nature microbiology 6 (7) (2021)
Mauro Giacca
Cardiac Regeneration After Myocardial Infarction: an Approachable Goal. Current cardiology reports 22 (10) (2020)
Gianluca Gortan Cappellari, Aneta Aleksova, Matteo Dal Ferro, Antonio Cannata, Annamaria Semolic, Michela Zanetti, Jochen Springer, Stefan D Anker, Mauro Giacca, Gianfranco Sinagra, Rocco Barazzoni
Preserved Skeletal Muscle Mitochondrial Function, Redox State, Inflammation and Mass in Obese Mice with Chronic Heart Failure. Nutrients 12 (11) (2020)
Noemi Gioelli, Federica Maione, Chiara Camillo, Michela Ghitti, Donatella Valdembri, Noemi Morello, Marie Darche, Lorena Zentilin, Gabriella Cagnoni, Yaqi Qiu, Mauro Giacca, Maurizio Giustetto, Michel Paques, Ilaria Cascone, Giovanna Musco, Luca Tamagnone, Enrico Giraudo, Guido Serini
A rationally designed NRP1-independent superagonist SEMA3A mutant is an effective anticancer agent. Science translational medicine 10 (442) (2019)
Hashim Ali, Miguel Mano, Luca Braga, Asma Naseem, Bruna Marini, Diem My Vu, Chiara Collesi, Germana Meroni, Marina Lusic, Mauro Giacca
Cellular TRIM33 restrains HIV-1 infection by targeting viral integrase for proteasomal degradation. Nature communications 10 (1) (2019)
Carmen Aguilar, Ana Rita Cruz, Ines Rodrigues Lopes, Claire Maudet, Ushasree Sunkavalli, Ricardo Jorge Silva, Malvika Sharan, Clivia Lisowski, Sara Zaldívar-López, Juan José Garrido, Mauro Giacca, Miguel Mano, Ana Eulalio
Functional screenings reveal different requirements for host microRNAs in Salmonella and Shigella infection. Nature microbiology 5 (1) (2019)
Hashim Ali, Luca Braga, Mauro Giacca
Cardiac regeneration and remodelling of the cardiomyocyte cytoarchitecture. The FEBS journal 287 (3) (2019)
Mariateresa Di Stazio, Chiara Collesi, Diego Vozzi, Wei Liu, Mike Myers, Anna Morgan, Pio Adamo D Adamo, Giorgia Girotto, Elisa Rubinato, Mauro Giacca, Paolo Gasparini
TBL1Y: a new gene involved in syndromic hearing loss. European journal of human genetics : EJHG 27 (3) (2018)
Maarten M G van den Hoogenhof, Ingeborg van der Made, Nina E de Groot, Amin Damanafshan, Shirley C M van Amersfoorth, Lorena Zentilin, Mauro Giacca, Yigal M Pinto, Esther E Creemers
AAV9-mediated Rbm24 overexpression induces fibrosis in the mouse heart. Scientific reports 8 (1) (2018)
Ilaria Secco, Lucio Barile, Consuelo Torrini, Lorena Zentilin, Giuseppe Vassalli, Mauro Giacca, Chiara Collesi
Notch pathway activation enhances cardiosphere in vitro expansion. Journal of cellular and molecular medicine 22 (11) (2018)
Serena Zacchigna, Valentina Martinelli, Silvia Moimas, Andrea Colliva, Marco Anzini, Andrea Nordio, Alessia Costa, Michael Rehman, Simone Vodret, Cristina Pierro, Giulia Colussi, Lorena Zentilin, Maria Ines Gutierrez, Ellen Dirkx, Carlin Long, Gianfranco Sinagra, David Klatzmann, Mauro Giacca
Paracrine effect of regulatory T cells promotes cardiomyocyte proliferation during pregnancy and after myocardial infarction. Nature communications 9 (1) (2018)
Justyna Broniarczyk, Nadja Ring, Paola Massimi, Mauro Giacca, Lawrence Banks
HPV-16 virions can remain infectious for 2 weeks on senescent cells but require cell cycle re-activation to allow virus entry. Scientific reports 8 (1) (2018)
Elena Sommariva, Yuri D'Alessandra, Floriana Maria Farina, Michela Casella, Fabio Cattaneo, Valentina Catto, Mattia Chiesa, Ilaria Stadiotti, Silvia Brambilla, Antonio Dello Russo, Corrado Carbucicchio, Giulia Vettor, Daniela Riggio, Maria Teresa Sandri, Andrea Barbuti, Gianluca Vernillo, Manuela Muratori, Matteo Dal Ferro, Gianfranco Sinagra, Silvia Moimas, Mauro Giacca, Gualtiero Ivanoe Colombo, Giulio Pompilio, Claudio Tondo
MiR-320a as a Potential Novel Circulating Biomarker of Arrhythmogenic CardioMyopathy. Scientific reports 7 (1) (2017)
Marta Codrich, Maria Bertuzzi, Roberta Russo, Margherita Francescatto, Stefano Espinoza, Lorena Zentilin, Mauro Giacca, Daniela Cesselli, Antonio Paolo Beltrami, Paolo Ascenzi, Silvia Zucchelli, Francesca Persichetti, Giampiero Leanza, Stefano Gustincich
Neuronal hemoglobin affects dopaminergic cells' response to stress. Cell death & disease 8 (1) (2017)
Heike Fuhrmann-Stroissnigg, Yuan Yuan Ling, Jing Zhao, Sara J McGowan, Yi Zhu, Robert W Brooks, Diego Grassi, Siobhan Q Gregg, Jennifer L Stripay, Akaitz Dorronsoro, Lana Corbo, Priscilla Tang, Christina Bukata, Nadja Ring, Mauro Giacca, Xuesen Li, Tamara Tchkonia, James L Kirkland, Laura J Niedernhofer, Paul D Robbins
Identification of HSP90 inhibitors as a novel class of senolytics. Nature communications 8 (1) (2017)
L Bočkor, G Bortolussi, A Iaconcig, G Chiaruttini, C Tiribelli, Mauro Giacca, F Benvenuti, L Zentilin, A F Muro
Repeated AAV-mediated gene transfer by serotype switching enables long-lasting therapeutic levels of hUgt1a1 enzyme in a mouse model of Crigler-Najjar Syndrome Type I. Gene therapy 24 (10) (2017)
Gianluca Gortan Cappellari, Michela Zanetti, Annamaria Semolic, Pierandrea Vinci, Giulia Ruozi, Antonella Falcione, Nicoletta Filigheddu, Gianfranco Guarnieri, Andrea Graziani, Mauro Giacca, Rocco Barazzoni
Unacylated Ghrelin Reduces Skeletal Muscle Reactive Oxygen Species Generation and Inflammation and Prevents High-Fat Diet-Induced Hyperglycemia and Whole-Body Insulin Resistance in Rodents. Diabetes 65 (4) (2016)

Mauro Giacca.css-eqlu8i{font-size:small;padding-left:4px;} (M Giacca)

Publication Activity (10 Years)

Top Topics

Top Venues

Mauro Giacca (M Giacca)