Marco W Fraaije (Marco Fraaije)

Loop profile ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 75

Top Venues

Applied microbiology and biotechnology

Nature communications

ACS synthetic biology

Chembiochem : a European journal of chemical biology

University of Groningen

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University of Groningen

Netherlands

full professor :: Molecular Enzymology

Publications

Gwen Tjallinks, Andrea Mattevi, Marco W Fraaije
Biosynthetic Strategies of Berberine Bridge Enzyme-like Flavoprotein Oxidases toward Structural Diversification in Natural Product Biosynthesis. Biochemistry (2024)
Lars L Santema, Laura Rotilio, Ruite Xiang, Gwen Tjallinks, Victor Guallar, Andrea Mattevi, Marco W Fraaije
Discovery and biochemical characterization of thermostable glycerol oxidases. Applied microbiology and biotechnology 108 (1) (2024)
Misun Lee, Marco W Fraaije
Equipping Saccharomyces cerevisiae with an Additional Redox Cofactor Allows F 420 -Dependent Bioconversions in Yeast. ACS synthetic biology 13 (3) (2024)
Lars L Santema, Laura Rotilio, Ruite Xiang, Gwen Tjallinks, Victor Guallar, Andrea Mattevi, Marco W Fraaije
Discovery and biochemical characterization of thermostable glycerol oxidases. Applied microbiology and biotechnology 108 (1) (2024)
Lars L Santema, Laura Rotilio, Ruite Xiang, Gwen Tjallinks, Victor Guallar, Andrea Mattevi, Marco W Fraaije
Discovery and biochemical characterization of thermostable glycerol oxidases. Applied microbiology and biotechnology 108 (1) (2024)
Gonzalo de de Gonzalo, Juan M Coto-Cid, Nikola Lončar, Marco W Fraaije
Asymmetric Sulfoxidations Catalyzed by Bacterial Flavin-Containing Monooxygenases. Molecules (Basel, Switzerland) 29 (15) (2024)
Alessandro Boverio, Neelam Jamil, Barbara Mannucci, María Laura Mascotti, Marco W Fraaije, Andrea Mattevi
Structure, mechanism, and evolution of the last step in vitamin C biosynthesis. Nature communications 15 (1) (2024)
Misun Lee, Marco W Fraaije
Equipping Saccharomyces cerevisiae with an Additional Redox Cofactor Allows F 420 -Dependent Bioconversions in Yeast. ACS synthetic biology 13 (3) (2024)
Misun Lee, Marco W Fraaije
Equipping Saccharomyces cerevisiae with an Additional Redox Cofactor Allows F 420 -Dependent Bioconversions in Yeast. ACS synthetic biology (2024)
Lars L Santema, Laura Rotilio, Ruite Xiang, Gwen Tjallinks, Victor Guallar, Andrea Mattevi, Marco W Fraaije
Discovery and biochemical characterization of thermostable glycerol oxidases. Applied microbiology and biotechnology 108 (1) (2024)
Misun Lee, Marco W Fraaije
Equipping Saccharomyces cerevisiae with an Additional Redox Cofactor Allows F 420 -Dependent Bioconversions in Yeast. ACS synthetic biology 13 (3) (2024)
Pimvisuth Chunkrua, Kai P Leschonski, Alejandro A Gran-Scheuch, Gijs J C Vreeke, Jean-Paul Vincken, Marco W Fraaije, Willem J H van Berkel, Wouter J C de Bruijn, Mirjam A Kabel
Prenylation of aromatic amino acids and plant phenolics by an aromatic prenyltransferase from Rasamsonia emersonii. Applied microbiology and biotechnology 108 (1) (2024)
Sara Russo, Henriette J Rozeboom, Hein J Wijma, Gerrit J Poelarends, Marco W Fraaije
Biochemical, kinetic, and structural characterization of a Bacillus tequilensis nitroreductase. The FEBS journal (2024)
Misun Lee, Marco W Fraaije
Equipping Saccharomyces cerevisiae with an Additional Redox Cofactor Allows F 420 -Dependent Bioconversions in Yeast. ACS synthetic biology 13 (3) (2024)
Misun Lee, Marco W Fraaije
Equipping Saccharomyces cerevisiae with an Additional Redox Cofactor Allows F 420 -Dependent Bioconversions in Yeast. ACS synthetic biology 13 (3) (2024)
Gonzalo de de Gonzalo, Juan M Coto-Cid, Nikola Lončar, Marco W Fraaije
Asymmetric Sulfoxidations Catalyzed by Bacterial Flavin-Containing Monooxygenases. Molecules (Basel, Switzerland) 29 (15) (2024)
Alessandro Boverio, Neelam Jamil, Barbara Mannucci, María Laura Mascotti, Marco W Fraaije, Andrea Mattevi
Structure, mechanism, and evolution of the last step in vitamin C biosynthesis. Nature communications 15 (1) (2024)
Gwen Tjallinks, Andrea Mattevi, Marco W Fraaije
Biosynthetic Strategies of Berberine Bridge Enzyme-like Flavoprotein Oxidases toward Structural Diversification in Natural Product Biosynthesis. Biochemistry 63 (17) (2024)
Pimvisuth Chunkrua, Kai P Leschonski, Alejandro A Gran-Scheuch, Gijs J C Vreeke, Jean-Paul Vincken, Marco W Fraaije, Willem J H van Berkel, Wouter J C de Bruijn, Mirjam A Kabel
Prenylation of aromatic amino acids and plant phenolics by an aromatic prenyltransferase from Rasamsonia emersonii. Applied microbiology and biotechnology 108 (1) (2024)
Lars L Santema, Laura Rotilio, Ruite Xiang, Gwen Tjallinks, Victor Guallar, Andrea Mattevi, Marco W Fraaije
Discovery and biochemical characterization of thermostable glycerol oxidases. Applied microbiology and biotechnology 108 (1) (2024)
Alessandro Boverio, Neelam Jamil, Barbara Mannucci, María Laura Mascotti, Marco W Fraaije, Andrea Mattevi
Structure, mechanism, and evolution of the last step in vitamin C biosynthesis. Nature communications 15 (1) (2024)
Pimvisuth Chunkrua, Kai P Leschonski, Alejandro A Gran-Scheuch, Gijs J C Vreeke, Jean-Paul Vincken, Marco W Fraaije, Willem J H van Berkel, Wouter J C de Bruijn, Mirjam A Kabel
Prenylation of aromatic amino acids and plant phenolics by an aromatic prenyltransferase from Rasamsonia emersonii. Applied microbiology and biotechnology 108 (1) (2024)
Lars L Santema, Laura Rotilio, Ruite Xiang, Gwen Tjallinks, Victor Guallar, Andrea Mattevi, Marco W Fraaije
Discovery and biochemical characterization of thermostable glycerol oxidases. Applied microbiology and biotechnology 108 (1) (2024)
Gautier Bailleul, Guang Yang, Callum R Nicoll, Andrea Mattevi, Marco W Fraaije, María Laura Mascotti
Evolution of enzyme functionality in the flavin-containing monooxygenases. Nature communications 14 (1) (2023)
Yiming Guo, Laura Alvigini, Mohammad Saifuddin, Ben Ashley, Milos Trajkovic, Lur Alonso-Cotchico, Andrea Mattevi, Marco W Fraaije
One-Pot Biocatalytic Synthesis of rac -Syringaresinol from a Lignin-Derived Phenol. ACS catalysis 13 (22) (2023)
Guang Yang, Hein J Wijma, Henriëtte J Rozeboom, Maria Laura Mascotti, Marco W Fraaije
Identification and characterization of archaeal and bacterial F 420 -dependent thioredoxin reductases. The FEBS journal (2023)
Gautier Bailleul, Guang Yang, Callum R Nicoll, Andrea Mattevi, Marco W Fraaije, María Laura Mascotti
Evolution of enzyme functionality in the flavin-containing monooxygenases. Nature communications 14 (1) (2023)
Gautier Bailleul, Guang Yang, Callum R Nicoll, Andrea Mattevi, Marco W Fraaije, María Laura Mascotti
Evolution of enzyme functionality in the flavin-containing monooxygenases. Nature communications 14 (1) (2023)
Lars L Santema, Lorenzo Basile, Claudia Binda, Marco W Fraaije
Discovery and structural characterization of a thermostable bacterial monoamine oxidase. The FEBS journal (2023)
Gautier Bailleul, Guang Yang, Callum R Nicoll, Andrea Mattevi, Marco W Fraaije, María Laura Mascotti
Evolution of enzyme functionality in the flavin-containing monooxygenases. Nature communications 14 (1) (2023)
Gautier Bailleul, Guang Yang, Callum R Nicoll, Andrea Mattevi, Marco W Fraaije, María Laura Mascotti
Evolution of enzyme functionality in the flavin-containing monooxygenases. Nature communications 14 (1) (2023)
Yapei Tong, Saniye G Kaya, Sara Russo, Henriette J Rozeboom, Hein J Wijma, Marco W Fraaije
Fixing Flavins: Hijacking a Flavin Transferase for Equipping Flavoproteins with a Covalent Flavin Cofactor. Journal of the American Chemical Society (2023)
Mark Arentshorst, Prajeesh Kooloth Valappil, László Mózsik, Tonny J G Regensburg-Tuïnk, Sjoerd Seekles, Gwen Tjallinks, Marco W Fraaije, Jaap Visser, Arthur F J Ram
A CRISPR/Cas9-based multicopy integration system for protein production in Aspergillus niger. The FEBS journal (2023)
Gwen Tjallinks, Alessandro Boverio, Ivana Maric, Henriette Rozeboom, Mark Arentshorst, Jaap Visser, Arthur F J Ram, Andrea Mattevi, Marco W Fraaije
Structure elucidation and characterization of patulin synthase, insights into the formation of a fungal mycotoxin. The FEBS journal (2023)
Yapei Tong, Marnix R Loonstra, Marco W Fraaije
Broadening the Scope of the Flavin-Tag Method by Improving Flavin Incorporation and Incorporating Flavin Analogs. Chembiochem : a European journal of chemical biology 23 (11) (2022)
Yiming Guo, Laura Alvigini, Miloš Trajković, Lur Alonso-Cotchico, Emanuele Monza, Simone Savino, Ivana Marić, Andrea Mattevi, Marco W Fraaije
Structure- and computational-aided engineering of an oxidase to produce isoeugenol from a lignin-derived compound. Nature communications 13 (1) (2022)
Alessandro Boverio, Wahyu S Widodo, Lars L Santema, Henriëtte J Rozeboom, Ruite Xiang, Victor Guallar, Andrea Mattevi, Marco W Fraaije
Structural Elucidation and Engineering of a Bacterial Carbohydrate Oxidase. Biochemistry (2022)
Silvia Venturi, Milos Trajkovic, Danilo Colombo, Elisabetta Brenna, Marco W Fraaije, Francesco G Gatti, Piero Macchi, Emilio Zamboni
Chemoenzymatic Synthesis of the Most Pleasant Stereoisomer of Jessemal. The Journal of organic chemistry 87 (9) (2022)
Misun Lee, Jeroen Drenth, Milos Trajkovic, René M de Jong, Marco W Fraaije
Introducing an Artificial Deazaflavin Cofactor in Escherichia coli and Saccharomyces cerevisiae . ACS synthetic biology 11 (2) (2022)
Elzbieta Rembeza, Alessandro Boverio, Marco W Fraaije, Martin K M Engqvist
Discovery of Two Novel Oxidases Using a High-Throughput Activity Screen. Chembiochem : a European journal of chemical biology (2021)
Lidia Zuccarello, Catarina Barbosa, Edilson Galdino, Nikola Lončar, Célia M Silveira, Marco W Fraaije, Smilja Todorovic
SERR Spectroelectrochemistry as a Guide for Rational Design of DyP-Based Bioelectronics Devices. International journal of molecular sciences 22 (15) (2021)
Ni Nyoman Purwani, Caterina Martin, Simone Savino, Marco W Fraaije
Modular Assembly of Phosphite Dehydrogenase and Phenylacetone Monooxygenase for Tuning Cofactor Regeneration. Biomolecules 11 (6) (2021)
Jeroen Drenth, Guang Yang, Caroline E Paul, Marco W Fraaije
A Tailor-Made Deazaflavin-Mediated Recycling System for Artificial Nicotinamide Cofactor Biomimetics. ACS catalysis 11 (18) (2021)
Yapei Tong, Misun Lee, Jeroen Drenth, Marco W Fraaije
Flavin-tag: A Facile Method for Site-Specific Labeling of Proteins with a Flavin Fluorophore. Bioconjugate chemistry 32 (8) (2021)
Ulises A Zitare, Mohamed H Habib, Henriette Rozeboom, Maria L Mascotti, Smilja Todorovic, Marco W Fraaije
Mutational and structural analysis of an ancestral fungal dye-decolorizing peroxidase. The FEBS journal 288 (11) (2021)
Tsvetan Kardashliev, Alexandra Weingartner, Elvira Romero, Ulrich Schwaneberg, Marco W Fraaije, Sven Panke, Martin Held
Whole-cell screening of oxidative enzymes using genetically encoded sensors. Chemical science 12 (44) (2021)
Reiko Ueoka, Roy A Meoded, Alejandro Gran-Scheuch, Agneya Bhushan, Marco W Fraaije, Jörn Piel
Genome Mining of Oxidation Modules in trans-Acyltransferase Polyketide Synthases Reveals a Culturable Source for Lobatamides. Angewandte Chemie (International ed. in English) 59 (20) (2020)
Elvira Romero, Simone Savino, Marco W Fraaije, Nikola Lončar
Mechanistic and Crystallographic Studies of Azoreductase AzoA from Bacillus wakoensis A01. ACS chemical biology 15 (2) (2020)
Friso S Aalbers, Maximillian J L J Fürst, Stefano Rovida, Milos Trajkovic, J Rubén Gómez Castellanos, Sebastian Bartsch, Andreas Vogel, Andrea Mattevi, Marco W Fraaije
Approaching boiling point stability of an alcohol dehydrogenase through computationally-guided enzyme engineering. eLife 9 (2020)
Caterina Martin, Miloš Trajković, Marco W Fraaije
Production of Hydroxy Acids: Selective Double Oxidation of Diols by Flavoprotein Alcohol Oxidase. Angewandte Chemie (International ed. in English) 59 (12) (2020)
Ramón Román, Nikola Lončar, Antoni Casablancas, Marco W Fraaije, Glòria Gonzalez
High-level production of industrially relevant oxidases by a two-stage fed-batch approach: overcoming catabolite repression in arabinose-inducible Escherichia coli systems. Applied microbiology and biotechnology 104 (12) (2020)
Caterina Martin, Gwen Tjallinks, Miloš Trajković, Marco W Fraaije
Facile Stereoselective Reduction of Prochiral Ketones by using an F420 -dependent Alcohol Dehydrogenase. Chembiochem : a European journal of chemical biology 22 (1) (2020)
Simone Savino, Sonja Jensen, Anke Terwisscha van Scheltinga, Marco W Fraaije
Analysis of the structure and substrate scope of chitooligosaccharide oxidase reveals high affinity for C2-modified glucosamines. FEBS letters 594 (17) (2020)
Célia M Silveira, Elin Moe, Marco W Fraaije, Lígia O Martins, Smilja Todorovic
Resonance Raman view of the active site architecture in bacterial DyP-type peroxidases. RSC advances 10 (19) (2020)
Maximillian J L J Fürst, Marjon Boonstra, Selle Bandstra, Marco W Fraaije
Stabilization of cyclohexanone monooxygenase by computational and experimental library design. Biotechnology and bioengineering 116 (9) (2019)
Mohamed H Habib, Henriëtte J Rozeboom, Marco W Fraaije
Characterization of a New DyP-Peroxidase from the Alkaliphilic Cellulomonad, Cellulomonas bogoriensis. Molecules (Basel, Switzerland) 24 (7) (2019)
Callum R Nicoll, Gautier Bailleul, Filippo Fiorentini, María Laura Mascotti, Marco W Fraaije, Andrea Mattevi
Ancestral-sequence reconstruction unveils the structural basis of function in mammalian FMOs. Nature structural & molecular biology 27 (1) (2019)
Andrea N Fabara, Marco W Fraaije
An overview of microbial indigo-forming enzymes. Applied microbiology and biotechnology 104 (3) (2019)
Nikola Lončar, Hugo L van Beek, Marco W Fraaije
Structure-Based Redesign of a Self-Sufficient Flavin-Containing Monooxygenase towards Indigo Production. International journal of molecular sciences 20 (24) (2019)
Nikola Lončar, Filippo Fiorentini, Gautier Bailleul, Simone Savino, Elvira Romero, Andrea Mattevi, Marco W Fraaije
Characterization of a thermostable flavin-containing monooxygenase from Nitrincola lacisaponensis (NiFMO). Applied microbiology and biotechnology 103 (4) (2019)
Friso S Aalbers, Marco W Fraaije
Design of Artificial Alcohol Oxidases: Alcohol Dehydrogenase-NADPH Oxidase Fusions for Continuous Oxidations. Chembiochem : a European journal of chemical biology 20 (1) (2018)
Quoc-Thai Nguyen, Elvira Romero, Willem P Dijkman, Suzan Pantaroto de Vasconcellos, Claudia Binda, Andrea Mattevi, Marco W Fraaije
Structure-Based Engineering of Phanerochaete chrysosporium Alcohol Oxidase for Enhanced Oxidative Power toward Glycerol. Biochemistry 57 (43) (2018)
Friso S Aalbers, Marco W Fraaije
Enzyme Fusions in Biocatalysis: Coupling Reactions by Pairing Enzymes. Chembiochem : a European journal of chemical biology 20 (1) (2018)
Mathias Pickl, Alexander Swoboda, Elvira Romero, Christoph K Winkler, Claudia Binda, Andrea Mattevi, Kurt Faber, Marco W Fraaije
Kinetic Resolution of sec-Thiols by Enantioselective Oxidation with Rationally Engineered 5-(Hydroxymethyl)furfural Oxidase. Angewandte Chemie (International ed. in English) 57 (11) (2018)
Guangyue Li, Marc Garcia-Borràs, Maximilian J L J Fürst, Adriana Ilie, Marco W Fraaije, Kendall N Houk, Manfred T Reetz
Overriding Traditional Electronic Effects in Biocatalytic Baeyer-Villiger Reactions by Directed Evolution. Journal of the American Chemical Society 140 (33) (2018)
Elvira Romero, J Rubén Gómez Castellanos, Giovanni Gadda, Marco W Fraaije, Andrea Mattevi
Same Substrate, Many Reactions: Oxygen Activation in Flavoenzymes. Chemical reviews 118 (4) (2018)
Alessandro R Ferrari, Henriëtte J Rozeboom, Aniek S C Vugts, Martijn J Koetsier, Robert Floor, Marco W Fraaije
Characterization of Two VAO-Type Flavoprotein Oxidases from Myceliophthora thermophila. Molecules (Basel, Switzerland) 23 (1) (2018)
María Laura Mascotti, Hemant Kumar, Quoc-Thai Nguyen, Maximiliano Juri Ayub, Marco W Fraaije
Reconstructing the evolutionary history of F420-dependent dehydrogenases. Scientific reports 8 (1) (2018)
Maximilian J L J Fürst, Simone Savino, Hanna M Dudek, J Rúben Gómez Castellanos, Cora Gutiérrez de Souza, Stefano Rovida, Marco W Fraaije, Andrea Mattevi
Polycyclic Ketone Monooxygenase from the Thermophilic Fungus Thermothelomyces thermophila: A Structurally Distinct Biocatalyst for Bulky Substrates. Journal of the American Chemical Society 139 (2) (2017)
Friso S Aalbers, Marco W Fraaije
Coupled reactions by coupled enzymes: alcohol to lactone cascade with alcohol dehydrogenase-cyclohexanone monooxygenase fusions. Applied microbiology and biotechnology 101 (20) (2017)
Filippo Fiorentini, Elvira Romero, Marco W Fraaije, Kurt Faber, Mélanie Hall, Andrea Mattevi
Baeyer-Villiger Monooxygenase FMO5 as Entry Point in Drug Metabolism. ACS chemical biology 12 (9) (2017)
Simon Burgener, Thomas Schwander, Elvira Romero, Marco W Fraaije, Tobias J Erb
Molecular Basis for Converting (2S)-Methylsuccinyl-CoA Dehydrogenase into an Oxidase. Molecules (Basel, Switzerland) 23 (1) (2017)
Dana I Colpa, Nikola Lončar, Mareike Schmidt, Marco W Fraaije
Creating Oxidase-Peroxidase Fusion Enzymes as a Toolbox for Cascade Reactions. Chembiochem : a European journal of chemical biology 18 (22) (2017)
Elvira Romero, J Rubén Gómez Castellanos, Andrea Mattevi, Marco W Fraaije
Characterization and Crystal Structure of a Robust Cyclohexanone Monooxygenase. Angewandte Chemie (International ed. in English) 55 (51) (2016)
Hugo L van Beek, Elvira Romero, Marco W Fraaije
Engineering Cyclohexanone Monooxygenase for the Production of Methyl Propanoate. ACS chemical biology 12 (1) (2016)

Marco W Fraaije.css-eqlu8i{font-size:small;padding-left:4px;} (Marco Fraaije)

Publication Activity (10 Years)

Top Topics

Top Venues

Marco W Fraaije (Marco Fraaije)