Andrea Mattevi

Scopus Author ID ResearcherID ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 56

Top Venues

Nature communications

Biochemistry

Applied microbiology and biotechnology

Nature chemical biology

Università degli Studi di Pavia

Rijksuniversiteit Groningen (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Università degli Studi di Pavia

Italy

Full Professor :: Department of Biology and Biotechnology

Università degli Studi di Pavia Dec 01 1993 - Dec 30 2000

Italy

Research Fellow :: Department Genetics and Microbiology

MRC Laboratory of Molecular Biology Nov 15 1992 - Oct 01 1993

United Kingdom

Post-doc

Education History

Rijksuniversiteit Groningen Sep 01 1988 - Nov 01 1992

Netherlands

PHD

Università degli Studi di Pavia Oct 01 1984 - Jul 24 1988

Italy

BSC :: Department Genetics and Microbiology

Publications

Kwangwoon Lee, Marco Barone, Amanda L Waterbury, Hanjie Jiang, Eunju Nam, Sarah E DuBois-Coyne, Samuel D Whedon, Zhipeng A Wang, Jonatan Caroli, Katherine Neal, Brian Ibeabuchi, Zuzer Dhoondia, Mitzi I Kuroda, Brian B Liau, Samuel Beck, Andrea Mattevi, Philip A Cole
Uncoupling histone modification crosstalk by engineering lysine demethylase LSD1. Nature chemical biology (2024)
Gwen Tjallinks, Andrea Mattevi, Marco W Fraaije
Biosynthetic Strategies of Berberine Bridge Enzyme-like Flavoprotein Oxidases toward Structural Diversification in Natural Product Biosynthesis. Biochemistry (2024)
Lars L Santema, Laura Rotilio, Ruite Xiang, Gwen Tjallinks, Victor Guallar, Andrea Mattevi, Marco W Fraaije
Discovery and biochemical characterization of thermostable glycerol oxidases. Applied microbiology and biotechnology 108 (1) (2024)
Lars L Santema, Laura Rotilio, Ruite Xiang, Gwen Tjallinks, Victor Guallar, Andrea Mattevi, Marco W Fraaije
Discovery and biochemical characterization of thermostable glycerol oxidases. Applied microbiology and biotechnology 108 (1) (2024)
Lars L Santema, Laura Rotilio, Ruite Xiang, Gwen Tjallinks, Victor Guallar, Andrea Mattevi, Marco W Fraaije
Discovery and biochemical characterization of thermostable glycerol oxidases. Applied microbiology and biotechnology 108 (1) (2024)
Sandhya Malla, Kanchan Kumari, Carlos A García-Prieto, Jonatan Caroli, Anna Nordin, Trinh T T Phan, Devi Prasad Bhattarai, Carlos Martinez-Gamero, Eshagh Dorafshan, Stephanie Stransky, Damiana Álvarez-Errico, Paulina Avovome Saiki, Weiyi Lai, Cong Lyu, Ludvig Lizana, Jonathan D Gilthorpe, Hai-Lin Wang, Simone Sidoli, André Mateus, Dung-Fang Lee, Claudio Cantú, Manel Esteller, Andrea Mattevi, Angel-Carlos Roman, Francesca Aguilo
The scaffolding function of LSD1 controls DNA methylation in mouse ESCs. Nature communications 15 (1) (2024)
Alessandro Boverio, Neelam Jamil, Barbara Mannucci, María Laura Mascotti, Marco W Fraaije, Andrea Mattevi
Structure, mechanism, and evolution of the last step in vitamin C biosynthesis. Nature communications 15 (1) (2024)
Lars L Santema, Laura Rotilio, Ruite Xiang, Gwen Tjallinks, Victor Guallar, Andrea Mattevi, Marco W Fraaije
Discovery and biochemical characterization of thermostable glycerol oxidases. Applied microbiology and biotechnology 108 (1) (2024)
Kwangwoon Lee, Marco Barone, Amanda L Waterbury, Hanjie Jiang, Eunju Nam, Sarah E DuBois-Coyne, Samuel D Whedon, Zhipeng A Wang, Jonatan Caroli, Katherine Neal, Brian Ibeabuchi, Zuzer Dhoondia, Mitzi I Kuroda, Brian B Liau, Samuel Beck, Andrea Mattevi, Philip A Cole
Uncoupling histone modification crosstalk by engineering lysine demethylase LSD1. Nature chemical biology (2024)
Kwangwoon Lee, Marco Barone, Amanda L Waterbury, Hanjie Jiang, Eunju Nam, Sarah E DuBois-Coyne, Samuel D Whedon, Zhipeng A Wang, Jonatan Caroli, Katherine Neal, Brian Ibeabuchi, Zuzer Dhoondia, Mitzi I Kuroda, Brian B Liau, Samuel Beck, Andrea Mattevi, Philip A Cole
Uncoupling histone modification crosstalk by engineering lysine demethylase LSD1. Nature chemical biology (2024)
Kwangwoon Lee, Marco Barone, Amanda L Waterbury, Hanjie Jiang, Eunju Nam, Sarah E DuBois-Coyne, Samuel D Whedon, Zhipeng A Wang, Jonatan Caroli, Katherine Neal, Brian Ibeabuchi, Zuzer Dhoondia, Mitzi I Kuroda, Brian B Liau, Samuel Beck, Andrea Mattevi, Philip A Cole
Uncoupling histone modification crosstalk by engineering lysine demethylase LSD1. Nature chemical biology (2024)
Alessandro Boverio, Neelam Jamil, Barbara Mannucci, María Laura Mascotti, Marco W Fraaije, Andrea Mattevi
Structure, mechanism, and evolution of the last step in vitamin C biosynthesis. Nature communications 15 (1) (2024)
Gwen Tjallinks, Andrea Mattevi, Marco W Fraaije
Biosynthetic Strategies of Berberine Bridge Enzyme-like Flavoprotein Oxidases toward Structural Diversification in Natural Product Biosynthesis. Biochemistry 63 (17) (2024)
Lars L Santema, Laura Rotilio, Ruite Xiang, Gwen Tjallinks, Victor Guallar, Andrea Mattevi, Marco W Fraaije
Discovery and biochemical characterization of thermostable glycerol oxidases. Applied microbiology and biotechnology 108 (1) (2024)
Megan Jin Rae Yeo, Olivia Zhang, Xiaowen Xie, Eunju Nam, Neil Connor Payne, Pallavi M Gosavi, Hui Si Kwok, Irtiza Iram, Ceejay Lee, Jiaming Li, Nicholas J Chen, Hanjie Jiang, Zhipeng A Wang, Kwangwoon Lee, Haibin Mao, Stefan Andrew Harry, Idris A Barakat, Mariko Takahashi, Amanda L Waterbury, Marco Barone, Andrea Mattevi, Liron Bar-Peled, Philip A Cole, Ralph Mazitschek, Brian B Liau, Ning Zheng
Asymmetric Engagement of Dimeric CRL3 KBTBD4 by the Molecular Glue UM171 Licenses Degradation of HDAC1/2 Complexes. bioRxiv : the preprint server for biology (2024)
Alessandro Boverio, Neelam Jamil, Barbara Mannucci, María Laura Mascotti, Marco W Fraaije, Andrea Mattevi
Structure, mechanism, and evolution of the last step in vitamin C biosynthesis. Nature communications 15 (1) (2024)
Lars L Santema, Laura Rotilio, Ruite Xiang, Gwen Tjallinks, Victor Guallar, Andrea Mattevi, Marco W Fraaije
Discovery and biochemical characterization of thermostable glycerol oxidases. Applied microbiology and biotechnology 108 (1) (2024)
Gautier Bailleul, Guang Yang, Callum R Nicoll, Andrea Mattevi, Marco W Fraaije, María Laura Mascotti
Evolution of enzyme functionality in the flavin-containing monooxygenases. Nature communications 14 (1) (2023)
Yiming Guo, Laura Alvigini, Mohammad Saifuddin, Ben Ashley, Milos Trajkovic, Lur Alonso-Cotchico, Andrea Mattevi, Marco W Fraaije
One-Pot Biocatalytic Synthesis of rac -Syringaresinol from a Lignin-Derived Phenol. ACS catalysis 13 (22) (2023)
Gautier Bailleul, Guang Yang, Callum R Nicoll, Andrea Mattevi, Marco W Fraaije, María Laura Mascotti
Evolution of enzyme functionality in the flavin-containing monooxygenases. Nature communications 14 (1) (2023)
Joana Reis, Christoph Gorgulla, Marta Massari, Sara Marchese, Sergio Valente, Beatrice Noce, Lorenzo Basile, Ricarda Törner, Huel Cox, Thibault Viennet, Moon Hee Yang, Melissa A Ronan, Matthew G Rees, Jennifer A Roth, Lucia Capasso, Angela Nebbioso, Lucia Altucci, Antonello Mai, Haribabu Arthanari, Andrea Mattevi
Targeting ROS production through inhibition of NADPH oxidases. Nature chemical biology (2023)
Gautier Bailleul, Guang Yang, Callum R Nicoll, Andrea Mattevi, Marco W Fraaije, María Laura Mascotti
Evolution of enzyme functionality in the flavin-containing monooxygenases. Nature communications 14 (1) (2023)
Gautier Bailleul, Guang Yang, Callum R Nicoll, Andrea Mattevi, Marco W Fraaije, María Laura Mascotti
Evolution of enzyme functionality in the flavin-containing monooxygenases. Nature communications 14 (1) (2023)
Gautier Bailleul, Guang Yang, Callum R Nicoll, Andrea Mattevi, Marco W Fraaije, María Laura Mascotti
Evolution of enzyme functionality in the flavin-containing monooxygenases. Nature communications 14 (1) (2023)
Gwen Tjallinks, Alessandro Boverio, Ivana Maric, Henriette Rozeboom, Mark Arentshorst, Jaap Visser, Arthur F J Ram, Andrea Mattevi, Marco W Fraaije
Structure elucidation and characterization of patulin synthase, insights into the formation of a fungal mycotoxin. The FEBS journal (2023)
Rossella Fioravanti, Veronica Rodriguez, Jonatan Caroli, Ugo Chianese, Rosaria Benedetti, Elisabetta Di Bello, Beatrice Noce, Clemens Zwergel, Davide Corinti, Dolores Viña, Lucia Altucci, Andrea Mattevi, Sergio Valente, Antonello Mai
Heterocycle-containing tranylcypromine derivatives endowed with high anti-LSD1 activity. Journal of enzyme inhibition and medicinal chemistry 37 (1) (2022)
Yiming Guo, Laura Alvigini, Miloš Trajković, Lur Alonso-Cotchico, Emanuele Monza, Simone Savino, Ivana Marić, Andrea Mattevi, Marco W Fraaije
Structure- and computational-aided engineering of an oxidase to produce isoeugenol from a lignin-derived compound. Nature communications 13 (1) (2022)
Alessandro Boverio, Wahyu S Widodo, Lars L Santema, Henriëtte J Rozeboom, Ruite Xiang, Victor Guallar, Andrea Mattevi, Marco W Fraaije
Structural Elucidation and Engineering of a Bacterial Carbohydrate Oxidase. Biochemistry (2022)
Mario De Simone, Laura Alvigini, Lur Alonso-Cotchico, Vânia Brissos, Jonatan Caroli, Maria Fátima Lucas, Emanuele Monza, Eduardo Pinho Melo, Andrea Mattevi, Lígia O Martins
Rationally Guided Improvement of NOV1 Dioxygenase for the Conversion of Lignin-Derived Isoeugenol to Vanillin. Biochemistry (2022)
Filippo Fiorentini, Callum R Nicoll, Andrea Mattevi
Baeyer-Villiger Monooxygenases and Their Mechanism of Oxygen Activation: From Microbes to Humans. Biochemistry 60 (46) (2021)
Andrea Mattevi
How evolution dismantles and reassembles multienzyme complexes. Proceedings of the National Academy of Sciences of the United States of America 119 (1) (2021)
Wout Oosterheert, Joana Reis, Piet Gros, Andrea Mattevi
An Elegant Four-Helical Fold in NOX and STEAP Enzymes Facilitates Electron Transport across Biomembranes-Similar Vehicle, Different Destination. Accounts of chemical research 53 (9) (2020)
Luca G Iacovino, Joana Reis, Antonello Mai, Claudia Binda, Andrea Mattevi
Diphenylene Iodonium Is a Noncovalent MAO Inhibitor: A Biochemical and Structural Analysis. ChemMedChem 15 (15) (2020)
Simon Ernst, Stefano Rovida, Andrea Mattevi, Susanne Fetzner, Steffen Lorenz Drees
Photoinduced monooxygenation involving NAD(P)H-FAD sequential single-electron transfer. Nature communications 11 (1) (2020)
Friso S Aalbers, Maximillian J L J Fürst, Stefano Rovida, Milos Trajkovic, J Rubén Gómez Castellanos, Sebastian Bartsch, Andreas Vogel, Andrea Mattevi, Marco W Fraaije
Approaching boiling point stability of an alcohol dehydrogenase through computationally-guided enzyme engineering. eLife 9 (2020)
Luca Giacinto Iacovino, Nicola Manzella, Jessica Resta, Maria Antonietta Vanoni, Laura Rotilio, Leonardo Pisani, Dale Edward Edmondson, Angelo Parini, Andrea Mattevi, Jeanne Mialet-Perez, Claudia Binda
Rational Redesign of Monoamine Oxidase A into a Dehydrogenase to Probe ROS in Cardiac Aging. ACS chemical biology 15 (7) (2020)
Luca Giacinto Iacovino, Simone Savino, Annika J E Borg, Claudia Binda, Bernd Nidetzky, Andrea Mattevi
Crystallographic snapshots of UDP-glucuronic acid 4-epimerase ligand binding, rotation, and reduction. The Journal of biological chemistry 295 (35) (2020)
Roberto Ravasio, Elena Ceccacci, Luciano Nicosia, Amir Hosseini, Pier Luigi Rossi, Iros Barozzi, Lorenzo Fornasari, Roberto Dal Zuffo, Sergio Valente, Rossella Fioravanti, Ciro Mercurio, Mario Varasi, Andrea Mattevi, Antonello Mai, Giulio Pavesi, Tiziana Bonaldi, Saverio Minucci
Targeting the scaffolding role of LSD1 (KDM1A) poises acute myeloid leukemia cells for retinoic acid-induced differentiation. Science advances 6 (15) (2020)
Marta Ceccon, Elisa Millana Fananas, Marta Massari, Andrea Mattevi, Francesca Magnani
Engineering stability in NADPH oxidases: A common strategy for enzyme production. Molecular membrane biology 34 (3-8) (2019)
Elisa Millana Fañanás, Sofia Todesca, Alessandro Sicorello, Laura Masino, Petr Pompach, Francesca Magnani, Annalisa Pastore, Andrea Mattevi
On the mechanism of calcium-dependent activation of NADPH oxidase 5 (NOX5). The FEBS journal 287 (12) (2019)
Callum R Nicoll, Gautier Bailleul, Filippo Fiorentini, María Laura Mascotti, Marco W Fraaije, Andrea Mattevi
Ancestral-sequence reconstruction unveils the structural basis of function in mammalian FMOs. Nature structural & molecular biology 27 (1) (2019)
Marco Montefiori, Simona Pilotto, Chiara Marabelli, Elisabetta Moroni, Mariarosaria Ferraro, Stefano A Serapian, Andrea Mattevi, Giorgio Colombo
Impact of Mutations on NPAC Structural Dynamics: Mechanistic Insights from MD Simulations. Journal of chemical information and modeling 59 (9) (2019)
Filippo Fiorentini, Anna-Maria Hatzl, Sandy Schmidt, Simone Savino, Anton Glieder, Andrea Mattevi
The Extreme Structural Plasticity in the CYP153 Subfamily of P450s Directs Development of Designer Hydroxylases. Biochemistry 57 (48) (2018)
Quoc-Thai Nguyen, Elvira Romero, Willem P Dijkman, Suzan Pantaroto de Vasconcellos, Claudia Binda, Andrea Mattevi, Marco W Fraaije
Structure-Based Engineering of Phanerochaete chrysosporium Alcohol Oxidase for Enhanced Oxidative Power toward Glycerol. Biochemistry 57 (43) (2018)
Jay H Kalin, Muzhou Wu, Andrea V Gomez, Yun Song, Jayanta Das, Dawn Hayward, Nkosi Adejola, Mingxuan Wu, Izabela Panova, Hye Jin Chung, Edward Kim, Holly J Roberts, Justin M Roberts, Polina Prusevich, Jeliazko R Jeliazkov, Shourya S Roy Burman, Louise Fairall, Charles Milano, Abdulkerim Eroglu, Charlotte M Proby, Albena T Dinkova-Kostova, Wayne W Hancock, Jeffrey J Gray, James E Bradner, Sergio Valente, Antonello Mai, Nicole M Anders, Michelle A Rudek, Yong Hu, Byungwoo Ryu, John W R Schwabe, Andrea Mattevi, Rhoda M Alani, Philip A Cole
Targeting the CoREST complex with dual histone deacetylase and demethylase inhibitors. Nature communications 9 (1) (2018)
Elvira Romero, J Rubén Gómez Castellanos, Giovanni Gadda, Marco W Fraaije, Andrea Mattevi
Same Substrate, Many Reactions: Oxygen Activation in Flavoenzymes. Chemical reviews 118 (4) (2018)
Wout Oosterheert, Laura S van Bezouwen, Remco N P Rodenburg, Joke Granneman, Friedrich Förster, Andrea Mattevi, Piet Gros
Cryo-EM structures of human STEAP4 reveal mechanism of iron(III) reduction. Nature communications 9 (1) (2018)
Maximilian J L J Fürst, Simone Savino, Hanna M Dudek, J Rúben Gómez Castellanos, Cora Gutiérrez de Souza, Stefano Rovida, Marco W Fraaije, Andrea Mattevi
Polycyclic Ketone Monooxygenase from the Thermophilic Fungus Thermothelomyces thermophila: A Structurally Distinct Biocatalyst for Bulky Substrates. Journal of the American Chemical Society 139 (2) (2017)
Marta Esposito, Sára Szadocka, Giulia Degiacomi, Beatrice S Orena, Giorgia Mori, Valentina Piano, Francesca Boldrin, Júlia Zemanová, Stanislav Huszár, David Barros, Sean Ekins, Joel Lelièvre, Riccardo Manganelli, Andrea Mattevi, Maria Rosalia Pasca, Giovanna Riccardi, Lluis Ballell, Katarína Mikušová, Laurent Roberto Chiarelli
A Phenotypic Based Target Screening Approach Delivers New Antitubercular CTP Synthetase Inhibitors. ACS infectious diseases 3 (6) (2017)
Federico Forneris, Andrea Mattevi
Expanding the structural biology toolbox with single-molecule holography. Proceedings of the National Academy of Sciences of the United States of America 114 (7) (2017)
Filippo Fiorentini, Elvira Romero, Marco W Fraaije, Kurt Faber, Mélanie Hall, Andrea Mattevi
Baeyer-Villiger Monooxygenase FMO5 as Entry Point in Drug Metabolism. ACS chemical biology 12 (9) (2017)
Luca Sartori, Ciro Mercurio, Federica Amigoni, Anna Cappa, Giovanni Fagá, Raimondo Fattori, Elena Legnaghi, Giuseppe Ciossani, Andrea Mattevi, Giuseppe Meroni, Loris Moretti, Valentina Cecatiello, Sebastiano Pasqualato, Alessia Romussi, Florian Thaler, Paolo Trifiró, Manuela Villa, Stefania Vultaggio, Oronza A Botrugno, Paola Dessanti, Saverio Minucci, Elisa Zagarrí, Daniele Carettoni, Lucia Iuzzolino, Mario Varasi, Paola Vianello
Thieno[3,2-b]pyrrole-5-carboxamides as New Reversible Inhibitors of Histone Lysine Demethylase KDM1A/LSD1. Part 1: High-Throughput Screening and Preliminary Exploration. Journal of medicinal chemistry 60 (5) (2017)
Francesca Magnani, Simone Nenci, Elisa Millana Fananas, Marta Ceccon, Elvira Romero, Marco W Fraaije, Andrea Mattevi
Crystal structures and atomic model of NADPH oxidase. Proceedings of the National Academy of Sciences of the United States of America 114 (26) (2017)
Paola Vianello, Luca Sartori, Federica Amigoni, Anna Cappa, Giovanni Fagá, Raimondo Fattori, Elena Legnaghi, Giuseppe Ciossani, Andrea Mattevi, Giuseppe Meroni, Loris Moretti, Valentina Cecatiello, Sebastiano Pasqualato, Alessia Romussi, Florian Thaler, Paolo Trifiró, Manuela Villa, Oronza A Botrugno, Paola Dessanti, Saverio Minucci, Stefania Vultaggio, Elisa Zagarrí, Mario Varasi, Ciro Mercurio
Thieno[3,2-b]pyrrole-5-carboxamides as New Reversible Inhibitors of Histone Lysine Demethylase KDM1A/LSD1. Part 2: Structure-Based Drug Design and Structure-Activity Relationship. Journal of medicinal chemistry 60 (5) (2017)
Elvira Romero, J Rubén Gómez Castellanos, Andrea Mattevi, Marco W Fraaije
Characterization and Crystal Structure of a Robust Cyclohexanone Monooxygenase. Angewandte Chemie (International ed. in English) 55 (51) (2016)
Valentina Speranzini, Dante Rotili, Giuseppe Ciossani, Simona Pilotto, Biagina Marrocco, Mariantonietta Forgione, Alessia Lucidi, Federico Forneris, Parinaz Mehdipour, Sameer Velankar, Antonello Mai, Andrea Mattevi
Polymyxins and quinazolines are LSD1/KDM1A inhibitors with unusual structural features. Science advances 2 (9) (2016)

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Publication Activity (10 Years)

Top Topics

Top Venues

Andrea Mattevi