Melissa H Little (Melissa Little)

ResearcherID ORCID

Publication Activity (10 Years)

Years Active: 2017-2023
Publications (10 Years): 22

Top Venues

Development (Cambridge, England)

Nature communications

Genome medicine

Nature reviews. Nephrology

University of Melbourne

University of Queensland (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University of Melbourne

Australia

Professor :: Paediatrics

Education History

University of Queensland Feb 1o 1986 - Feb 1o 1989

Australia

PHD :: Biochemistry

Publications

Jessica M Vanslambrouck, Ker Sin Tan, Sophia Mah, Melissa H Little
Generation of proximal tubule-enhanced kidney organoids from human pluripotent stem cells. Nature protocols (2023)
Joseph C Maggiore, Ryan LeGraw, Aneta J Przepiorski, Jeremy Velazquez, Christopher Chaney, Evan Streeter, Anne C S Barbosa, Jonathan M Franks, Joshua Hislop, Alex Hill, Haojia Wu, Katherine E Pfister, Sara E Howden, Simon C Watkins, Melissa H Little, Benjamin D Humphreys, Alan M Watson, Donna Beer Stolz, Samira Kiani, Alan J Davidson, Thomas J Carroll, Ondine Cleaver, Sunder Sims-Lucas, Mo R Ebrahimkhani, Neil A Hukriede
Genetically engineering endothelial niche in human kidney organoids enables multilineage maturation, vascularization and de novo cell types. bioRxiv : the preprint server for biology (2023)
Jessica M Vanslambrouck, Sean B Wilson, Ker Sin Tan, Ella Groenewegen, Rajeev Rudraraju, Jessica A Neil, Kynan T Lawlor, Sophia Mah, Michelle Scurr, Sara E Howden, Kanta Subbarao, Melissa H Little
Enhanced metanephric specification to functional proximal tubule enables toxicity screening and infectious disease modelling in kidney organoids. Nature communications 13 (1) (2022)
Francine S Ke, Steven Holloway, Rachel T Uren, Agnes W Wong, Melissa H Little, Ruth M Kluck, Anne K Voss, Andreas Strasser
The BCL-2 family member BID plays a role during embryonic development in addition to its BH3-only protein function by acting in parallel to BAX, BAK and BOK. The EMBO journal 41 (15) (2022)
Sean B Wilson, Sara E Howden, Jessica M Vanslambrouck, Aude Dorison, Jose Alquicira-Hernandez, Joseph E Powell, Melissa H Little
DevKidCC allows for robust classification and direct comparisons of kidney organoid datasets. Genome medicine 14 (1) (2022)
Melissa H Little, Sara E Howden, Kynan T Lawlor, Jessica M Vanslambrouck
Determining lineage relationships in kidney development and disease. Nature reviews. Nephrology (2021)
Amar J Majmundar, Florian Buerger, Thomas A Forbes, Verena Klämbt, Friedhelm Hildebrandt, Konstantin Deutsch, Thomas M Kitzler, Sara E Howden, Michelle Scurr, Ker Sin Tan, Mickaël Krzeminski, Eugen Widmeier, Daniela A Braun, Ethan Lai, Ihsan Ullah, Ali Amar, Amy Kolb, Kaitlyn Eddy, Chin Heng Chen, Daanya Salmanullah, Rufeng Dai, Makiko Nakayama, Isabel Ottlewski, Caroline M Kolvenbach, Ana C Onuchic-Whitford, Youying Mao, Nina Mann, Marwa M Nabhan, Seymour Rosen, Julie Deborah Forman-Kay, Neveen A Soliman, Andreas Heilos, Renate Kain, Christoph Aufricht, Shrikant M Mane, Richard P Lifton, Shirlee Shril, Melissa H Little, Friedhelm Hildebrandt
Recessive NOS1AP variants impair actin remodeling and cause glomerulopathy in humans and mice. Science advances 7 (1) (2021)
Sean B Wilson, Melissa H Little
The origin and role of the renal stroma. Development (Cambridge, England) 148 (19) (2021)
Nick R Glass, Minoru Takasako, Pei Xuan Er, Drew M Titmarsh, Alejandro Hidalgo, Ernst J Wolvetang, Melissa H Little, Justin J Cooper-White
Multivariate patterning of human pluripotent cells under perfusion reveals critical roles of induced paracrine factors in kidney organoid development. Science advances 6 (2) (2020)
Alena V Yermalovich, Jihan K Osborne, Patricia Sousa, Areum Han, Melissa A Kinney, Michael J Chen, Daisy A Robinton, Helen Montie, Dan S Pearson, Sean B Wilson, Alexander N Combes, Melissa H Little, George Q Daley
Author Correction: Lin28 and let-7 regulate the timing of cessation of murine nephrogenesis. Nature communications 11 (1) (2020)
Melissa H Little, Kynan T Lawlor
Recreating, expanding and using nephron progenitor populations. Nature reviews. Nephrology 16 (2) (2020)
Kynan T Lawlor, Jessica M Vanslambrouck, J William Higgins, Alison Chambon, Kristina Bishard, Derek Arndt, Pei Xuan Er, Sean B Wilson, Sara E Howden, Ker Sin Tan, Fanyi Li, Lorna J Hale, Benjamin Shepherd, Stephen Pentoney, Sharon C Presnell, Alice E Chen, Melissa H Little
Cellular extrusion bioprinting improves kidney organoid reproducibility and conformation. Nature materials 20 (2) (2020)
Santhosh V Kumar, Pei X Er, Kynan T Lawlor, Ali Motazedian, Michelle Scurr, Irene Ghobrial, Alexander N Combes, Luke Zappia, Alicia Oshlack, Edouard G Stanley, Melissa H Little
Kidney micro-organoids in suspension culture as a scalable source of human pluripotent stem cell-derived kidney cells. Development (Cambridge, England) 146 (5) (2019)
Sara E Howden, Jessica M Vanslambrouck, Sean B Wilson, Ker Sin Tan, Melissa H Little
Reporter-based fate mapping in human kidney organoids confirms nephron lineage relationships and reveals synchronous nephron formation. EMBO reports 20 (4) (2019)
Melissa H Little, Catherine Quinlan
Advances in our understanding of genetic kidney disease using kidney organoids. Pediatric nephrology (Berlin, Germany) 35 (6) (2019)
Alena V Yermalovich, Jihan K Osborne, Patricia Sousa, Areum Han, Melissa A Kinney, Michael J Chen, Daisy A Robinton, Helen Montie, Dan S Pearson, Sean B Wilson, Alexander N Combes, Melissa H Little, George Q Daley
Lin28 and let-7 regulate the timing of cessation of murine nephrogenesis. Nature communications 10 (1) (2019)
Alexander N Combes, Luke Zappia, Pei Xuan Er, Alicia Oshlack, Melissa H Little
Single-cell analysis reveals congruence between kidney organoids and human fetal kidney. Genome medicine 11 (1) (2019)
Alexander N Combes, Belinda Phipson, Kynan T Lawlor, Aude Dorison, Ralph Patrick, Luke Zappia, Richard P Harvey, Alicia Oshlack, Melissa H Little
Single cell analysis of the developing mouse kidney provides deeper insight into marker gene expression and ligand-receptor crosstalk. Development (Cambridge, England) 146 (12) (2019)
Belinda Phipson, Pei X Er, Alexander N Combes, Thomas A Forbes, Sara E Howden, Luke Zappia, Hsan-Jan Yen, Kynan T Lawlor, Lorna J Hale, Jane Sun, Ernst Wolvetang, Minoru Takasato, Alicia Oshlack, Melissa H Little
Evaluation of variability in human kidney organoids. Nature methods 16 (1) (2018)
Lorna J Hale, Sara E Howden, Belinda Phipson, Andrew Lonsdale, Pei X Er, Irene Ghobrial, Salman Hosawi, Sean B Wilson, Kynan T Lawlor, Shahnaz Khan, Alicia Oshlack, Catherine Quinlan, Rachel Lennon, Melissa H Little
3D organoid-derived human glomeruli for personalised podocyte disease modelling and drug screening. Nature communications 9 (1) (2018)
Melissa H Little
Organoids: a Special Issue. Development (Cambridge, England) 144 (6) (2017)
James G Lefevre, Han S Chiu, Alexander N Combes, Jessica M Vanslambrouck, Ali Ju, Nicholas A Hamilton, Melissa H Little
Self-organisation after embryonic kidney dissociation is driven via selective adhesion of ureteric epithelial cells. Development (Cambridge, England) 144 (6) (2017)

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Publication Activity (10 Years)

Top Topics

Top Venues

Melissa H Little (Melissa Little)