Michael Kugler

Scopus Author ID ResearcherID ORCID

Publication Activity (10 Years)

Years Active: 2020-2023
Publications (10 Years): 11

Top Topics

Molecular Dynamics Simulations

Binding Protein

Pluripotent Stem Cells

Top Venues

Physical chemistry chemical physics : PCCP

RSC medicinal chemistry

Chemistry (Weinheim an der Bergstrasse, Germany)

Journal of enzyme inhibition and medicinal chemistry

This page only lists publications with an associated author ORCID identifier.

Publications

Jindřich Fanfrlík, Jiří Brynda, Michael Kugler, Martin Lepsik, Klára Pospíšilová, Josef Holub, Drahomír Hnyk, Jan Nekvinda, Bohumir Grüner, Pavlína Řezáčová
B-H⋯π and C-H⋯π interactions in protein-ligand complexes: carbonic anhydrase II inhibition by carborane sulfonamides. Physical chemistry chemical physics : PCCP 25 (3) (2023)
Jindřich Fanfrlík, Jiří Brynda, Michael Kugler, Martin Lepsik, Klára Pospíšilová, Josef Holub, Drahomír Hnyk, Jan Nekvinda, Bohumir Grüner, Pavlína Řezáčová
B-H⋯π and C-H⋯π interactions in protein-ligand complexes: carbonic anhydrase II inhibition by carborane sulfonamides. Physical chemistry chemical physics : PCCP (2023)
Jindřich Fanfrlík, Jiří Brynda, Michael Kugler, Martin Lepsik, Klára Pospíšilová, Josef Holub, Drahomír Hnyk, Jan Nekvinda, Bohumir Grüner, Pavlína Řezáčová
B-H⋯π and C-H⋯π interactions in protein-ligand complexes: carbonic anhydrase II inhibition by carborane sulfonamides. Physical chemistry chemical physics : PCCP 25 (3) (2023)
Jindřich Fanfrlík, Jiří Brynda, Michael Kugler, Martin Lepsik, Klára Pospíšilová, Josef Holub, Drahomír Hnyk, Jan Nekvinda, Bohumir Grüner, Pavlína Řezáčová
B-H⋯π and C-H⋯π interactions in protein-ligand complexes: carbonic anhydrase II inhibition by carborane sulfonamides. Physical chemistry chemical physics : PCCP 25 (3) (2023)
Felix J Metzner, Simon J Wenzl, Michael Kugler, Stefan Krebs, Karl-Peter Hopfner, Katja Lammens
Mechanistic understanding of human SLFN11. Nature communications 13 (1) (2022)
Michael Kugler, Martin Hadzima, Rastislav Dzijak, Robert Rampmaier, Pavel Srb, Lukáš Vrzal, Zdeněk Voburka, Pavel Majer, Pavlína Řezáčová, Milan Vrabel
Identification of specific carbonic anhydrase inhibitors via in situ click chemistry, phage-display and synthetic peptide libraries: comparison of the methods and structural study. RSC medicinal chemistry 14 (1) (2022)
Michael Kugler, Martin Hadzima, Rastislav Dzijak, Robert Rampmaier, Pavel Srb, Lukáš Vrzal, Zdeněk Voburka, Pavel Majer, Pavlína Řezáčová, Milan Vrabel
Identification of specific carbonic anhydrase inhibitors via in situ click chemistry, phage-display and synthetic peptide libraries: comparison of the methods and structural study. RSC medicinal chemistry 14 (1) (2022)
Michael Kugler, Josef Holub, Jiří Brynda, Klára Pospíšilová, Suzan El Anwar, Dmytro Bavol, Miroslav Havránek, Vlastimil Král, Milan Fábry, Bohumir Grüner, Pavlína Řezáčová
The structural basis for the selectivity of sulfonamido dicarbaboranes toward cancer-associated carbonic anhydrase IX. Journal of enzyme inhibition and medicinal chemistry 35 (1) (2021)
Michael Kugler, Jan Nekvinda, Josef Holub, Suzan El Anwar, Viswanath Das, Václav Šícha, Klára Pospíšilová, Milan Fabry, Vlastimil Král, Jiří Brynda, Václav Kašička, Marian Hajduch, Pavlína Řezáčová, Bohumir Grüner
Inhibitors of CA IX Enzyme Based on Polyhedral Boron Compounds. Chembiochem : a European journal of chemical biology 22 (18) (2021)
Bohumir Grüner, Michael Kugler, Suzan El Anwar, Josef Holub, Jan Nekvinda, Dmytro Bavol, Zdeňka Růžičková, Klára Pospíšilová, Milan Fabry, Vlastimil Král, Jiří Brynda, Pavlína Řezáčová
Cobalt Bis(dicarbollide) Alkylsulfonamides: Potent and Highly Selective Inhibitors of Tumor Specific Carbonic Anhydrase IX. ChemPlusChem 86 (3) (2020)
Jan Nekvinda, Michael Kugler, Josef Holub, Suzan El Anwar, Jiří Brynda, Klára Pospíšilová, Zdeňka Růžičková, Pavlína Řezáčová, Bohumir Grüner
Direct Introduction of an Alkylsulfonamido Group on C-sites of Isomeric Dicarba-closo-dodecaboranes: The Influence of Stereochemistry on Inhibitory Activity against the Cancer-Associated Carbonic Anhydrase IX Isoenzyme. Chemistry (Weinheim an der Bergstrasse, Germany) 26 (69) (2020)