Martin Lepsik (Martin Lepšík)

ResearcherID Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2018-2023
Publications (10 Years): 15

Top Topics

Protein Protein

Candida Albicans

Molecular Dynamics

Top Venues

Physical chemistry chemical physics : PCCP

Chemphyschem : a European journal of chemical physics and physical chemistry

Journal of molecular recognition : JMR

ACS infectious diseases

This page only lists publications with an associated author ORCID identifier.

Publications

Jindřich Fanfrlík, Jiří Brynda, Michael Kugler, Martin Lepsik, Klára Pospíšilová, Josef Holub, Drahomír Hnyk, Jan Nekvinda, Bohumir Grüner, Pavlína Řezáčová
B-H⋯π and C-H⋯π interactions in protein-ligand complexes: carbonic anhydrase II inhibition by carborane sulfonamides. Physical chemistry chemical physics : PCCP 25 (3) (2023)
Jindřich Fanfrlík, Jiří Brynda, Michael Kugler, Martin Lepsik, Klára Pospíšilová, Josef Holub, Drahomír Hnyk, Jan Nekvinda, Bohumir Grüner, Pavlína Řezáčová
B-H⋯π and C-H⋯π interactions in protein-ligand complexes: carbonic anhydrase II inhibition by carborane sulfonamides. Physical chemistry chemical physics : PCCP (2023)
Jindřich Fanfrlík, Jiří Brynda, Michael Kugler, Martin Lepsik, Klára Pospíšilová, Josef Holub, Drahomír Hnyk, Jan Nekvinda, Bohumir Grüner, Pavlína Řezáčová
B-H⋯π and C-H⋯π interactions in protein-ligand complexes: carbonic anhydrase II inhibition by carborane sulfonamides. Physical chemistry chemical physics : PCCP 25 (3) (2023)
Jindřich Fanfrlík, Jiří Brynda, Michael Kugler, Martin Lepsik, Klára Pospíšilová, Josef Holub, Drahomír Hnyk, Jan Nekvinda, Bohumir Grüner, Pavlína Řezáčová
B-H⋯π and C-H⋯π interactions in protein-ligand complexes: carbonic anhydrase II inhibition by carborane sulfonamides. Physical chemistry chemical physics : PCCP 25 (3) (2023)
Felix Tobola, Martin Lepsik, Syeda Rehana Zia, Hakon Leffler, Ulf J Nilsson, Nina Persson, Anne Imberty, Birgit Wiltschi
Engineering the Ligand Specificity of the Human Galectin-1 by Incorporation of Tryptophan Analogues. Chembiochem : a European journal of chemical biology 23 (5) (2022)
Eva Zahorska, Sakonwan Kuhaudomlarp, Saverio Minervini, Sultaan Yousaf, Martin Lepsik, Thorsten Kinsinger, Anna Katharina Herta Hirsch, Anne Imberty, Alexander Titz
A rapid synthesis of low-nanomolar divalent LecA inhibitors in four linear steps from d-galactose pentaacetate. Chemical communications (Cambridge, England) 56 (62) (2021)
Jiří Dostál, Jiří Brynda, Lucie Vaňková, Syeda Rehana Zia, Iva Pichová, Olga Heidingsfeld, Martin Lepsik
Structural determinants for subnanomolar inhibition of the secreted aspartic protease Sapp1p from Candida parapsilosis. Journal of enzyme inhibition and medicinal chemistry 36 (1) (2021)
Adam Pecina, Saltuk M Eyrilmez, Cemal Köprülüoğlu, Vijay Madhav Miriyala, Martin Lepsik, Jindřich Fanfrlík, Jan Řezáč, Pavel Hobza
SQM/COSMO Scoring Function: Reliable Quantum-Mechanical Tool for Sampling and Ranking in Structure-Based Drug Design. ChemPlusChem 85 (11) (2020)
Cemal Köprülüoğlu, Milan Dejmek, Michal Šála, Haresh Ajani, Hubert Hřebabecký, Jindřich Fanfrlík, Radek Jorda, Martin Dračínský, Eliška Procházková, Pavel Šácha, Vladimír Kryštof, Pavel Hobza, Martin Lepsik, Radim Nencka
Optimization of norbornyl-based carbocyclic nucleoside analogs as cyclin-dependent kinase 2 inhibitors. Journal of molecular recognition : JMR 33 (8) (2020)
Adéla Jílková, Petra Rubešová, Jindřich Fanfrlík, Pavla Fajtová, Pavlína Řezáčová, Jiří Brynda, Martin Lepsik, Helena Mertlíková-Kaiserová, Cory D Emal, Adam R Renslo, William R Roush, Martin Horn, Conor R Caffrey, Michael Mareš
Druggable Hot Spots in the Schistosomiasis Cathepsin B1 Target Identified by Functional and Binding Mode Analysis of Potent Vinyl Sulfone Inhibitors. ACS infectious diseases 7 (5) (2020)
Adam Pecina, Saltuk M Eyrilmez, Cemal Köprülüoğlu, Vijay Madhav Miriyala, Martin Lepsik, Jindřich Fanfrlík, Jan Řezáč, Pavel Hobza
SQM/COSMO Scoring Function: Reliable Quantum-Mechanical Tool for Sampling and Ranking in Structure-Based Drug Design. ChemPlusChem 85 (11) (2020)
Michael Mareš, Martin Horn, Jindřich Fanfrlík, Jim Küppers, Petr Pachl, Pavlína Řezáčová, Martin Lepsik, Pavla Fajtová, Petra Rubešová, Marta Chanová, Conor R Caffrey, Michael Gütschow, Michael Mareš
Azanitrile Inhibitors of the SmCB1 Protease Target Are Lethal to Schistosoma mansoni: Structural and Mechanistic Insights into Chemotype Reactivity. ACS infectious diseases 7 (1) (2020)
Jindřich Fanfrlík, Adam Pecina, Jan Řezáč, Martin Lepsik, Menyhárt-Botond Sárosi, Drahomír Hnyk, Pavel Hobza
Benchmark Data Sets of Boron Cluster Dihydrogen Bonding for the Validation of Approximate Computational Methods. Chemphyschem : a European journal of chemical physics and physical chemistry 21 (23) (2020)
Kristian Kříž, Jindřich Fanfrlík, Martin Lepsik
Chalcogen Bonding in Protein-Ligand Complexes: PDB Survey and Quantum Mechanical Calculations. Chemphyschem : a European journal of chemical physics and physical chemistry 19 (19) (2018)
Haresh Ajani, Josef Jansa, Cemal Köprülüoğlu, Pavel Hobza, Vladimír Kryštof, Antonín Lyčka, Martin Lepsik
Imidazo[1,2-c]pyrimidin-5(6H)-one as a novel core of cyclin-dependent kinase 2 inhibitors: Synthesis, activity measurement, docking, and quantum mechanical scoring. Journal of molecular recognition : JMR 31 (9) (2018)