Michael P Epstein (Michael Epstein)

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 43

Top Topics

Machine Learning

Genome Wide Association

Dna Methylation

Top Venues

medRxiv : the preprint server for health sciences

bioRxiv : the preprint server for biology

Nature communications

Genome medicine

This page only lists publications with an associated author ORCID identifier.

Publications

Randy L Parrish, Aron S Buchman, Shinya Tasaki, Yangling Wang, Denis Avey, Jishu Xu, Philip Lawrence De Jager, David A Bennett, Michael P Epstein, Jingjing Yang
SR-TWAS: leveraging multiple reference panels to improve transcriptome-wide association study power by ensemble machine learning. Nature communications 15 (1) (2024)
Andrew J Bass, Shijia Bian, Aliza P Wingo, Thomas S Wingo, David J Cutler, Michael P Epstein
Identifying latent genetic interactions in genome-wide association studies using multiple traits. Genome medicine 16 (1) (2024)
Andrew J Bass, Shijia Bian, Aliza P Wingo, Thomas S Wingo, David J Cutler, Michael P Epstein
Identifying latent genetic interactions in genome-wide association studies using multiple traits. Genome medicine 16 (1) (2024)
Tingyang Hu, Qile Dai, Michael P Epstein, Jingjing Yang
Proteome-wide association studies using summary proteomic data identified 23 risk genes of Alzheimer's disease. medRxiv : the preprint server for health sciences (2024)
Tingyang Hu, Qile Dai, Michael P Epstein, Jingjing Yang
Proteome-wide association studies using summary proteomic data identified 23 risk genes of Alzheimer's disease. medRxiv : the preprint server for health sciences (2024)
Tingyang Hu, Qile Dai, Michael P Epstein, Jingjing Yang
Proteome-wide association studies using summary proteomic data identified 23 risk genes of Alzheimer's disease. medRxiv : the preprint server for health sciences (2024)
Andrew J Bass, Shijia Bian, Aliza P Wingo, Thomas S Wingo, David J Cutler, Michael P Epstein
Identifying latent genetic interactions in genome-wide association studies using multiple traits. Genome medicine 16 (1) (2024)
Randy L Parrish, Aron S Buchman, Shinya Tasaki, Yangling Wang, Denis Avey, Jishu Xu, Philip Lawrence De Jager, David A Bennett, Michael P Epstein, Jingjing Yang
SR-TWAS: leveraging multiple reference panels to improve transcriptome-wide association study power by ensemble machine learning. Nature communications 15 (1) (2024)
Andrew J Bass, Shijia Bian, Aliza P Wingo, Thomas S Wingo, David J Cutler, Michael P Epstein
Identifying latent genetic interactions in genome-wide association studies using multiple traits. Genome medicine 16 (1) (2024)
Kelsey Robinson, Randy Parrish, Wasiu Lanre Adeyemo, Terri H Beaty, Azeez Butali, Carmen J Buxó, Lord Jj Gowans, Jacqueline T Hecht, Lina Moreno, Jeffrey C Murray, Gary M Shaw, Seth M Weinberg, Harrison Brand, Mary L Marazita, David J Cutler, Michael P Epstein, Jingjing Yang, Elizabeth J Leslie
Genome-wide study of gene-by-sex interactions identifies risks for cleft palate. medRxiv : the preprint server for health sciences (2024)
Tingyang Hu, Qile Dai, Michael P Epstein, Jingjing Yang
Proteome-wide association studies using summary proteomic data identified 23 risk genes of Alzheimer's disease. medRxiv : the preprint server for health sciences (2024)
Andrew J Bass, Shijia Bian, Aliza P Wingo, Thomas S Wingo, David J Cutler, Michael P Epstein
Identifying latent genetic interactions in genome-wide association studies using multiple traits. Genome medicine 16 (1) (2024)
Randy L Parrish, Aron S Buchman, Shinya Tasaki, Yangling Wang, Denis Avey, Jishu Xu, Philip Lawrence De Jager, David A Bennett, Michael P Epstein, Jingjing Yang
SR-TWAS: leveraging multiple reference panels to improve transcriptome-wide association study power by ensemble machine learning. Nature communications 15 (1) (2024)
Jing Huang, Chenyang Yuan, Jiahui Jiang, Jianfeng Chen, Sunil S Badve, Yesim Gokmen-Polar, Rossana L Segura, Xinmiao Yan, Alexander Lazar, Jianjun Gao, Michael P Epstein, Linghua Wang, Jian Hu
MorphLink: Bridging Cell Morphological Behaviors and Molecular Dynamics in Multi-modal Spatial Omics. bioRxiv : the preprint server for biology (2024)
Randy L Parrish, Aron S Buchman, Shinya Tasaki, Yangling Wang, Denis Avey, Jishu Xu, Philip Lawrence De Jager, David A Bennett, Michael P Epstein, Jingjing Yang
SR-TWAS: leveraging multiple reference panels to improve transcriptome-wide association study power by ensemble machine learning. Nature communications 15 (1) (2024)
Junyu Chen, Michael P Epstein, Joellen M Schildkraut, Siddhartha P Kar
Mapping inherited genetic variation with opposite effects on autoimmune disease and cancer identifies candidate drug targets associated with the anti-tumor immune response. medRxiv : the preprint server for health sciences (2023)
Kimberly K Diaz Perez, Sydney Chung, S Taylor Head, Michael P Epstein, Jacqueline T Hecht, George L Wehby, Seth M Weinberg, Jeffrey C Murray, Mary L Marazita, Elizabeth J Leslie
Rare variants found in multiplex families with orofacial clefts: Does expanding the phenotype make a difference? medRxiv : the preprint server for health sciences (2023)
Erik C B Johnson, Shijia Bian, Rafi U Haque, E Kathleen Carter, Caroline M Watson, Brian A Gordon, Lingyan Ping, Duc M Duong, Michael P Epstein, Eric McDade, Nicolas R Barthélemy, Celeste M Karch, Chengjie Xiong, Cruchaga Carlos, Richard J Perrin, Aliza P Wingo, Thomas S Wingo, Jasmeer P Chhatwal, Gregory S Day, James M Noble, Sarah B Berman, Ralph Martins, Neill R Graff-Radford, Peter R Schofield, Takeshi Ikeuchi, Hiroshi Mori, Johannes Levin, Martin R Farlow, James J Lah, Christian Haass, Mathias Jucker, John C Morris, Tammie L S Benzinger, Blaine R Roberts, Randell J Bateman, Anne M Fagan, Nicholas T Seyfried, Allan L Levey, null null
Cerebrospinal fluid proteomics define the natural history of autosomal dominant Alzheimer's disease. Nature medicine (2023)
Junyu Chen, Michael P Epstein, Joellen M Schildkraut, Siddhartha P Kar
Mapping inherited genetic variation with opposite effects on autoimmune disease and cancer identifies candidate drug targets associated with the anti-tumor immune response. medRxiv : the preprint server for health sciences (2023)
Andrew J Bass, Shijia Bian, Aliza P Wingo, Thomas S Wingo, David J Cutler, Michael P Epstein
Identifying latent genetic interactions in genome-wide association studies using multiple traits. bioRxiv : the preprint server for biology (2023)
Junyu Chen, Michael P Epstein, Joellen M Schildkraut, Siddhartha P Kar
Mapping inherited genetic variation with opposite effects on autoimmune disease and cancer identifies candidate drug targets associated with the anti-tumor immune response. medRxiv : the preprint server for health sciences (2023)
Kelsey Robinson, Trenell J Mosley, Kenneth S Rivera-González, Christopher R Jabbarpour, Sarah W Curtis, Wasiu Lanre Adeyemo, Terri H Beaty, Azeez Butali, Carmen J Buxó, David J Cutler, Michael P Epstein, Lord Jj Gowans, Jacqueline T Hecht, Jeffrey C Murray, Gary M Shaw, Lina Moreno Uribe, Seth M Weinberg, Harrison Brand, Mary L Marazita, Robert J Lipinski, Elizabeth J Leslie
Trio-based GWAS identifies novel associations and subtype-specific risk factors for cleft palate. medRxiv : the preprint server for health sciences (2023)
Aliza P Wingo, Yue Liu, Ekaterina S Gerasimov, Selina M Vattathil, Jiaqi Liu, David J Cutler, Michael P Epstein, Gabriëlla A M Blokland, Madhav Thambisetty, Juan C Troncoso, Duc M Duong, David A Bennett, Allan L Levey, Nicholas T Seyfried, Thomas S Wingo
Sex differences in brain protein expression and disease. Nature medicine (2023)
Kimberly K Diaz Perez, Sydney Chung, S Taylor Head, Michael P Epstein, Jacqueline T Hecht, George L Wehby, Seth M Weinberg, Jeffrey C Murray, Mary L Marazita, Elizabeth J Leslie
Rare variants found in multiplex families with orofacial clefts: Does expanding the phenotype make a difference? medRxiv : the preprint server for health sciences (2023)
Qile Dai, Michael P Epstein, Jingjing Yang
STACCato: Supervised Tensor Analysis tool for studying Cell-cell Communication using scRNA-seq data across multiple samples and conditions. bioRxiv : the preprint server for biology (2023)
Qile Dai, Michael P Epstein, Jingjing Yang
STACCato: Supervised Tensor Analysis tool for studying Cell-cell Communication using scRNA-seq data across multiple samples and conditions. bioRxiv : the preprint server for biology (2023)
Qile Dai, Geyu Zhou, Hongyu Zhao, Urmo Võsa, Lude H Franke, Alexis J Battle, Alexander Teumer, Terho Lehtimäki, Olli T Raitakari, Tõnu Esko, null null, Michael P Epstein, Jingjing Yang
OTTERS: a powerful TWAS framework leveraging summary-level reference data. Nature communications 14 (1) (2023)
Qile Dai, Michael P Epstein, Jingjing Yang
STACCato: Supervised Tensor Analysis tool for studying Cell-cell Communication using scRNA-seq data across multiple samples and conditions. bioRxiv : the preprint server for biology (2023)
Junyu Chen, Michael P Epstein, Joellen M Schildkraut, Siddhartha P Kar
Mapping inherited genetic variation with opposite effects on autoimmune disease and cancer identifies candidate drug targets associated with the anti-tumor immune response. medRxiv : the preprint server for health sciences (2023)
Qile Dai, Geyu Zhou, Hongyu Zhao, Urmo Võsa, Lude H Franke, Alexis J Battle, Alexander Teumer, Terho Lehtimäki, Olli T Raitakari, Tõnu Esko, null null, Michael P Epstein, Jingjing Yang
OTTERS: a powerful TWAS framework leveraging summary-level reference data. Nature communications 14 (1) (2023)
S Taylor Head, Felipe Dezem, Andrei Todor, Jingjing Yang, Jasmine T Plummer, Simon Gayther, Siddhartha Kar, Joellen Schildkraut, Michael P Epstein
Cis - and trans -eQTL TWAS of breast and ovarian cancer identify more than 100 risk associated genes in the BCAC and OCAC consortia. bioRxiv : the preprint server for biology (2023)
Qile Dai, Michael P Epstein, Jingjing Yang
STACCato: Supervised Tensor Analysis tool for studying Cell-cell Communication using scRNA-seq data across multiple samples and conditions. bioRxiv : the preprint server for biology (2023)
Qile Dai, Michael P Epstein, Jingjing Yang
STACCato: Supervised Tensor Analysis tool for studying Cell-cell Communication using scRNA-seq data across multiple samples and conditions. bioRxiv : the preprint server for biology (2023)
Qile Dai, Geyu Zhou, Hongyu Zhao, Urmo Võsa, Lude H Franke, Alexis J Battle, Alexander Teumer, Terho Lehtimäki, Olli T Raitakari, Tõnu Esko, null null, Michael P Epstein, Jingjing Yang
OTTERS: a powerful TWAS framework leveraging summary-level reference data. Nature communications 14 (1) (2023)
Sarah W Curtis, Jenna C Carlson, Terri H Beaty, Jeffrey C Murray, Seth M Weinberg, Mary L Marazita, Justin L Cotney, David J Cutler, Michael P Epstein, Elizabeth J Leslie
Rare genetic variants in SEC24D modify orofacial cleft phenotypes. medRxiv : the preprint server for health sciences (2023)
Glen A Satten, Sarah W Curtis, Claudia R Solis-Lemus, Elizabeth J Leslie, Michael P Epstein
Efficient estimation of indirect effects in case-control studies using a unified likelihood framework. Statistics in medicine 41 (15) (2022)
Rebecca M Pollak, Ryan H Purcell, Timothy P Rutkowski, Tamika Malone, Kimberly J Pachura, Gary J Bassell, Michael P Epstein, Paul A Dawson, Matthew Ryan Smith, Dean P Jones, Michael E Zwick, Stephen T Warren, Tamara Caspary, David Weinshenker, Jennifer Gladys Mulle
Metabolic effects of the schizophrenia-associated 3q29 deletion. Translational psychiatry 12 (1) (2022)
Aliza P Wingo, Yue Liu, Ekaterina S Gerasimov, Jake Gockley, Benjamin A Logsdon, Duc M Duong, Eric B Dammer, Chloe Robins, Thomas G Beach, Eric M Reiman, Michael P Epstein, Philip Lawrence De Jager, James J Lah, David A Bennett, Nicholas T Seyfried, Allan L Levey, Thomas S Wingo
Integrating human brain proteomes with genome-wide association data implicates new proteins in Alzheimer's disease pathogenesis. Nature genetics 53 (2) (2021)
Emily Drzymalla, Nicole Gladish, Nastassja Koen, Michael P Epstein, Michael S Kobor, Heather J Zar, Dan J Stein, Anke Hüls
Association between maternal depression during pregnancy and newborn DNA methylation. Translational psychiatry 11 (1) (2021)
Thomas S Wingo, Yue Liu, Ekaterina Sergeevna Gerasimov, Jake Gockley, Benjamin A Logsdon, Duc M Duong, Eric B Dammer, Adriana Lori, Paul J Kim, Kerry James Ressler, Thomas G Beach, Eric M Reiman, Michael P Epstein, Philip Lawrence De Jager, James J Lah, David A Bennett, Nicholas T Seyfried, Allan L Levey, Aliza P Wingo
Brain proteome-wide association study implicates novel proteins in depression pathogenesis. Nature neuroscience 24 (6) (2021)
Anke Hüls, Chloe Robins, Karen N Conneely, Philip Lawrence De Jager, David A Bennett, Michael P Epstein, Thomas S Wingo, Aliza P Wingo
Association between DNA methylation levels in brain tissue and late-life depression in community-based participants. Translational psychiatry 10 (1) (2020)
Claudia R Solis-Lemus, S Taylor Fischer, Andrei Todor, Cuining Liu, Elizabeth J Leslie, David J Cutler, Debashis Ghosh, Michael P Epstein
Leveraging Family History in Case-Control Analyses of Rare Variation. Genetics 214 (2) (2019)
S Taylor Fischer, Yunxuan Jiang, K Alaine Broadaway, Karen N Conneely, Michael P Epstein
Powerful and robust cross-phenotype association test for case-parent trios. Genetic epidemiology 42 (5) (2018)