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Celeste M Karch (Celeste Karch, C M Karch)

Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2016-2023
Publications (10 Years): 51

Top Venues

Nature communications

Translational psychiatry

medRxiv : the preprint server for health sciences

Science translational medicine

Washington University in St Louis

University of Florida College of Medicine (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Washington University in St Louis

United States

Assistant Professor of Psychiatry :: Psychiatry

Education History

University of Florida College of Medicine

United States

PHD

Publications

Jiaxin Cindy Tu, Peter R Millar, Jeremy F Strain, Andrew Eck, Babatunde Adeyemo, Alisha Daniels, Celeste M Karch, Edward D Huey, Eric McDade, Gregory S Day, Igor Yakushev, Jason Hassenstab, John Morris, Jorge J Llibre-Guerra, Laura Ibañez, Mathias Jucker, Patricio Chrem Mendez, Randell J Bateman, Richard J Perrin, Tammie L S Benzinger, Clifford R Jack, Richard Betzel, Beau M Ances, Adam T Eggebrecht, Brian A Gordon, Muriah D Wheelock, null null
Increasing hub disruption parallels dementia severity in autosomal dominant Alzheimer disease. bioRxiv : the preprint server for biology (2023)
Logan Brase, Shih-Feng You, Ricardo D'Oliveira Albanus, Jorge L Del-Aguila, Yaoyi Dai, Brenna C Novotny, Carolina Soriano-Tarraga, Taitea Dykstra, Maria Victoria Fernandez, John P Budde, Kristy Bergmann, John C Morris, Randell J Bateman, Richard J Perrin, Eric McDade, Chengjie Xiong, Alison Mary Goate, Martin Farlow, null null, Greg Trevor Sutherland, Jonathan Kipnis, Celeste M Karch, Bruno A Benitez, Oscar Harari
Single-nucleus RNA-sequencing of autosomal dominant Alzheimer disease and risk variant carriers. Nature communications 14 (1) (2023)
Erik C B Johnson, Shijia Bian, Rafi U Haque, E Kathleen Carter, Caroline M Watson, Brian A Gordon, Lingyan Ping, Duc M Duong, Michael P Epstein, Eric McDade, Nicolas R Barthélemy, Celeste M Karch, Chengjie Xiong, Carlos Cruchaga, Richard J Perrin, Aliza P Wingo, Thomas S Wingo, Jasmeer P Chhatwal, Gregory S Day, James M Noble, Sarah B Berman, Ralph Martins, Neill R Graff-Radford, Peter R Schofield, Takeshi Ikeuchi, Hiroshi Mori, Johannes Levin, Martin R Farlow, James J Lah, Christian Haass, Mathias Jucker, John C Morris, Tammie L S Benzinger, Blaine R Roberts, Randell J Bateman, Anne M Fagan, Nicholas T Seyfried, Allan I Levey, null null
Cerebrospinal fluid proteomics define the natural history of autosomal dominant Alzheimer's disease. Nature medicine (2023)
Logan Brase, Shih-Feng You, Ricardo D'Oliveira Albanus, Jorge L Del-Aguila, Yaoyi Dai, Brenna C Novotny, Carolina Soriano-Tarraga, Taitea Dykstra, Maria Victoria Fernandez, John P Budde, Kristy Bergmann, John C Morris, Randell J Bateman, Richard J Perrin, Eric McDade, Chengjie Xiong, Alison Mary Goate, Martin Farlow, null null, Greg Trevor Sutherland, Jonathan Kipnis, Celeste M Karch, Bruno A Benitez, Oscar Harari
Single-nucleus RNA-sequencing of autosomal dominant Alzheimer disease and risk variant carriers. Nature communications 14 (1) (2023)
Logan Brase, Shih-Feng You, Ricardo D'Oliveira Albanus, Jorge L Del-Aguila, Yaoyi Dai, Brenna C Novotny, Carolina Soriano-Tarraga, Taitea Dykstra, Maria Victoria Fernandez, John P Budde, Kristy Bergmann, John C Morris, Randell J Bateman, Richard J Perrin, Eric McDade, Chengjie Xiong, Alison Mary Goate, Martin Farlow, null null, Greg Trevor Sutherland, Jonathan Kipnis, Celeste M Karch, Bruno A Benitez, Oscar Harari
Single-nucleus RNA-sequencing of autosomal dominant Alzheimer disease and risk variant carriers. Nature communications 14 (1) (2023)
Shih-Feng You, Logan Brase, Fabia Filipello, Abhirami K Iyer, Jorge Del-Aguila, June He, Ricardo D'Oliveira Albanus, John Budde, Joanne Norton, Jen Gentsch, Nina M Dräger, Sydney M Sattler, Martin Kampmann, Laura Piccio, John C Morris, Richard J Perrin, Eric McDade, null null, Steven M Paul, Anil G Cashikar, Bruno A Benitez, Oscar Harari, Celeste M Karch
MS4A4A modifies the risk of Alzheimer disease by regulating lipid metabolism and immune response in a unique microglia state. medRxiv : the preprint server for health sciences (2023)
Shih-Feng You, Logan Brase, Fabia Filipello, Abhirami K Iyer, Jorge Del-Aguila, June He, Ricardo D'Oliveira Albanus, John Budde, Joanne Norton, Jen Gentsch, Nina M Dräger, Sydney M Sattler, Martin Kampmann, Laura Piccio, John C Morris, Richard J Perrin, Eric McDade, null null, Steven M Paul, Anil G Cashikar, Bruno A Benitez, Oscar Harari, Celeste M Karch
MS4A4A modifies the risk of Alzheimer disease by regulating lipid metabolism and immune response in a unique microglia state. medRxiv : the preprint server for health sciences (2023)
Reshma Bhagat, Miguel A Minaya, Arun Renganathan, Muneshwar Mehra, Jacob Marsh, Rita Martinez, Alissa L Nana, Salvatore Spina, William W Seeley, Lea T Grinberg, Celeste M Karch
Long non-coding RNA SNHG8 drives stress granule formation in tauopathies. medRxiv : the preprint server for health sciences (2023)
Shih-Feng You, Logan Brase, Fabia Filipello, Abhirami K Iyer, Jorge Del-Aguila, June He, Ricardo D'Oliveira Albanus, John Budde, Joanne Norton, Jen Gentsch, Nina M Dräger, Sydney M Sattler, Martin Kampmann, Laura Piccio, John C Morris, Richard J Perrin, Eric McDade, null null, Steven M Paul, Anil G Cashikar, Bruno A Benitez, Oscar Harari, Celeste M Karch
MS4A4A modifies the risk of Alzheimer disease by regulating lipid metabolism and immune response in a unique microglia state. medRxiv : the preprint server for health sciences (2023)
Yun Ju Sung, Chengran Yang, Joanne Norton, Matt Johnson, Anne Fagan, Randell J Bateman, Richard J Perrin, John C Morris, Martin R Farlow, Jasmeer P Chhatwal, Peter R Schofield, Helena Chui, Fengxian Wang, Brenna C Novotny, Abdallah M Eteleeb, Celeste M Karch, Suzanne E Schindler, Herve Rhinn, Erik C B Johnson, Hamilton Se-Hwee Oh, Jarod Evert Rutledge, Eric B Dammer, Nicholas T Seyfried, Tony Wyss-Coray, Oscar Harari, Carlos Cruchaga
Proteomics of brain, CSF, and plasma identifies molecular signatures for distinguishing sporadic and genetic Alzheimer's disease. Science translational medicine 15 (703) (2023)
Logan Brase, Shih-Feng You, Ricardo D'Oliveira Albanus, Jorge L Del-Aguila, Yaoyi Dai, Brenna C Novotny, Carolina Soriano-Tarraga, Taitea Dykstra, Maria Victoria Fernandez, John P Budde, Kristy Bergmann, John C Morris, Randell J Bateman, Richard J Perrin, Eric McDade, Chengjie Xiong, Alison Mary Goate, Martin Farlow, null null, Greg Trevor Sutherland, Jonathan Kipnis, Celeste M Karch, Bruno A Benitez, Oscar Harari
Single-nucleus RNA-sequencing of autosomal dominant Alzheimer disease and risk variant carriers. Nature communications 14 (1) (2023)
Elke Gabriel, Walid Albanna, Giovanni Pasquini, Anand Ramani, Natasa Josipovic, Aruljothi Mariappan, Maria Giovanna Riparbelli, Giuliano Callaini, Celeste M Karch, Olivier Goureau, Argyris Papantonis, Volker Busskamp, Toni Schneider, Jay Gopalakrishnan
Generation of iPSC-derived human forebrain organoids assembling bilateral eye primordia. Nature protocols (2023)
Nicole S McKay, Brian A Gordon, Russ C Hornbeck, Aylin Dincer, Shaney Flores, Sarah J Keefe, Nelly Joseph-Mathurin, Clifford R Jack, Robert Koeppe, Peter R Millar, Beau M Ances, Charles D Chen, Alisha Daniels, Diana A Hobbs, Kelley Jackson, Deborah Koudelis, Parinaz Massoumzadeh, Austin McCullough, Michael L Nickels, Farzaneh Rahmani, Laura Swisher, Qing Wang, Ricardo Francisco Allegri, Sarah B Berman, Adam M Brickman, William S Brooks, David M Cash, Jasmeer P Chhatwal, Gregory S Day, Martin R Farlow, Christian Peter la Fougère, Nick C Fox, Michael J Fulham, Bernardino F Ghetti, Neill Graff-Radford, Takeshi Ikeuchi, William Klunk, Jae-Hong Lee, Johannes Levin, Ralph Martins, Colin L Masters, Jonathan McConathy, Hiroshi Mori, James M Noble, Gerald Reischl, Christopher Rowe, Stephen P Salloway, Raquel Sanchez-Valle, Peter R Schofield, Hiroyuki Shimada, Mikio Shoji, Yi Su, Kazushi Suzuki, Jonathan Vöglein, Igor Yakushev, Carlos Cruchaga, Jason Hassenstab, Celeste M Karch, Eric McDade, Richard J Perrin, Chengjie Xiong, John C Morris, Randell J Bateman, Tammie L S Benzinger, null null
Positron emission tomography and magnetic resonance imaging methods and datasets within the Dominantly Inherited Alzheimer Network (DIAN). Nature neuroscience (2023)
Abhirami K Iyer, Kathleen M Schoch, Anthony Verbeck, Grant Galasso, Hao Chen, Sarah Smith, Anna Oldenborg, Timothy M Miller, Celeste M Karch, Azad Bonni
Targeted ASO-mediated Atp1a2 knockdown in astrocytes reduces SOD1 aggregation and accelerates disease onset in mutant SOD1 mice. PloS one 18 (11) (2023)
Logan Brase, Shih-Feng You, Ricardo D'Oliveira Albanus, Jorge L Del-Aguila, Yaoyi Dai, Brenna C Novotny, Carolina Soriano-Tarraga, Taitea Dykstra, Maria Victoria Fernandez, John P Budde, Kristy Bergmann, John C Morris, Randell J Bateman, Richard J Perrin, Eric McDade, Chengjie Xiong, Alison Mary Goate, Martin Farlow, null null, Greg Trevor Sutherland, Jonathan Kipnis, Celeste M Karch, Bruno A Benitez, Oscar Harari
Single-nucleus RNA-sequencing of autosomal dominant Alzheimer disease and risk variant carriers. Nature communications 14 (1) (2023)
Zhao Sun, Ji-Sun Kwon, Yudong Ren, Shawei Chen, Kitra Cates, Xinguo Lu, Courtney K Walker, Hande Karahan, Sanja Sviben, James A J Fitzpatrick, Clarissa Valdez, Henry Houlden, Celeste M Karch, Randell J Bateman, Chihiro Sato, Steven J Mennerick, Marc I Diamond, Jungsu Kim, Rudolph E Tanzi, David M Holtzman, Andrew S Yoo
Endogenous recapitulation of Alzheimer's disease neuropathology through human 3D direct neuronal reprogramming. bioRxiv : the preprint server for biology (2023)
Lisa Vermunt, C Sutphen, E Dicks, D M de Leeuw, R Allegri, S B Berman, David M Cash, J P Chhatwal, Carlos Cruchaga, G Day, M Ewers, M Farlow, N C Fox, B Ghetti, N Graff-Radford, J Hassenstab, Mathias Jucker, Celeste M Karch, J Kuhle, C Laske, J Levin, C L Masters, E McDade, H Mori, J C Morris, R J Perrin, O Preische, Peter R Schofield, M Suárez-Calvet, C Xiong, Philip Scheltens, Charlotte E Teunissen, Pieter Jelle Visser, Randell J Bateman, Tammie L S Benzinger, A M Fagan, Brian A Gordon, Betty M Tijms
Axonal damage and astrocytosis are biological correlates of grey matter network integrity loss: a cohort study in autosomal dominant Alzheimer disease. medRxiv : the preprint server for health sciences (2023)
Logan Brase, Shih-Feng You, Ricardo D'Oliveira Albanus, Jorge L Del-Aguila, Yaoyi Dai, Brenna C Novotny, Carolina Soriano-Tarraga, Taitea Dykstra, Maria Victoria Fernandez, John P Budde, Kristy Bergmann, John C Morris, Randell J Bateman, Richard J Perrin, Eric McDade, Chengjie Xiong, Alison Mary Goate, Martin Farlow, null null, Greg Trevor Sutherland, Jonathan Kipnis, Celeste M Karch, Bruno A Benitez, Oscar Harari
Single-nucleus RNA-sequencing of autosomal dominant Alzheimer disease and risk variant carriers. Nature communications 14 (1) (2023)
Reshma Bhagat, Miguel A Minaya, Arun Renganathan, Muneshwar Mehra, Jacob Marsh, Rita Martinez, Alissa L Nana, Salvatore Spina, William W Seeley, Lea T Grinberg, Celeste M Karch
Long non-coding RNA SNHG8 drives stress granule formation in tauopathies. medRxiv : the preprint server for health sciences (2023)
Logan Brase, Shih-Feng You, Ricardo D'Oliveira Albanus, Jorge L Del-Aguila, Yaoyi Dai, Brenna C Novotny, Carolina Soriano-Tarraga, Taitea Dykstra, Maria Victoria Fernandez, John P Budde, Kristy Bergmann, John C Morris, Randell J Bateman, Richard J Perrin, Eric McDade, Chengjie Xiong, Alison Mary Goate, Martin Farlow, null null, Greg Trevor Sutherland, Jonathan Kipnis, Celeste M Karch, Bruno A Benitez, Oscar Harari
Single-nucleus RNA-sequencing of autosomal dominant Alzheimer disease and risk variant carriers. Nature communications 14 (1) (2023)
Reshma Bhagat, Miguel A Minaya, Arun Renganathan, Muneshwar Mehra, Jacob Marsh, Rita Martinez, Alissa L Nana, Salvatore Spina, William W Seeley, Lea T Grinberg, Celeste M Karch
Long non-coding RNA SNHG8 drives stress granule formation in tauopathies. medRxiv : the preprint server for health sciences (2023)
Reshma Bhagat, Miguel A Minaya, Arun Renganathan, Muneshwar Mehra, Jacob Marsh, Rita Martinez, Abdallah M Eteleeb, Alissa L Nana, Salvatore Spina, William W Seeley, Lea Tenenholz Grinberg, Celeste M Karch
Long non-coding RNA SNHG8 drives stress granule formation in tauopathies. Molecular psychiatry (2023)
Logan Brase, Shih-Feng You, Ricardo D'Oliveira Albanus, Jorge L Del-Aguila, Yaoyi Dai, Brenna C Novotny, Carolina Soriano-Tarraga, Taitea Dykstra, Maria Victoria Fernandez, John P Budde, Kristy Bergmann, John C Morris, Randell J Bateman, Richard J Perrin, Eric McDade, Chengjie Xiong, Alison Mary Goate, Martin Farlow, null null, Greg Trevor Sutherland, Jonathan Kipnis, Celeste M Karch, Bruno A Benitez, Oscar Harari
Single-nucleus RNA-sequencing of autosomal dominant Alzheimer disease and risk variant carriers. Nature communications 14 (1) (2023)
Sidhartha Mahali, Rita Martinez, Melvin King, Anthony Verbeck, Oscar Harari, Bruno A Benitez, Kanta Horie, Chihiro Sato, Sally Temple, Celeste M Karch
Defective proteostasis in induced pluripotent stem cell models of frontotemporal lobar degeneration. Translational psychiatry 12 (1) (2022)
Sidhartha Mahali, Rita Martinez, Melvin King, Anthony Verbeck, Oscar Harari, Bruno A Benitez, Kanta Horie, Chihiro Sato, Sally Temple, Celeste M Karch
Defective proteostasis in induced pluripotent stem cell models of frontotemporal lobar degeneration. Translational psychiatry 12 (1) (2022)
Sidhartha Mahali, Rita Martinez, Melvin King, Anthony Verbeck, Oscar Harari, Bruno A Benitez, Kanta Horie, Chihiro Sato, Sally Temple, Celeste M Karch
Defective proteostasis in induced pluripotent stem cell models of frontotemporal lobar degeneration. Translational psychiatry 12 (1) (2022)
Sidhartha Mahali, Rita Martinez, Melvin King, Anthony Verbeck, Oscar Harari, Bruno A Benitez, Kanta Horie, Chihiro Sato, Sally Temple, Celeste M Karch
Defective proteostasis in induced pluripotent stem cell models of frontotemporal lobar degeneration. Translational psychiatry 12 (1) (2022)
Carolyn N Mann, Shamulailatpam Shreedarshanee Devi, Corey T Kersting, Amber V Bleem, Celeste M Karch, David M Holtzman, Gilbert Gallardo
Astrocytic α2-Na + /K + ATPase inhibition suppresses astrocyte reactivity and reduces neurodegeneration in a tauopathy mouse model. Science translational medicine 14 (632) (2022)
Sidhartha Mahali, Rita Martinez, Melvin King, Anthony Verbeck, Oscar Harari, Bruno A Benitez, Kanta Horie, Chihiro Sato, Sally Temple, Celeste M Karch
Defective proteostasis in induced pluripotent stem cell models of frontotemporal lobar degeneration. Translational psychiatry 12 (1) (2022)
Sidhartha Mahali, Rita Martinez, Melvin King, Anthony Verbeck, Oscar Harari, Bruno A Benitez, Kanta Horie, Chihiro Sato, Sally Temple, Celeste M Karch
Defective proteostasis in induced pluripotent stem cell models of frontotemporal lobar degeneration. Translational psychiatry 12 (1) (2022)
Brenna C Novotny, Maria Victoria Fernandez, Ciyang Wang, John P Budde, Kristy Bergmann, Abdallah M Eteleeb, Joseph Bradley, Carol Webster, Curtis Ebl, Joanne Norton, Jen Gentsch, Umber Dube, Fengxian Wang, John C Morris, Randell J Bateman, Richard J Perrin, Eric McDade, Chengjie Xiong, Jasmeer P Chhatwal, null null, null null, null null, Alison Mary Goate, Martin Farlow, Peter R Schofield, Helena Chui, Celeste M Karch, Carlos Cruchaga, Bruno A Benitez, Oscar Harari
Metabolomic and lipidomic signatures in autosomal dominant and late-onset Alzheimer's disease brains. Alzheimer's & dementia : the journal of the Alzheimer's Association (2022)
Kanta Horie, Nicolas R Barthélemy, Salvatore Spina, Lawren VandeVrede, Yingxin He, Ross W Paterson, Brenton A Wright, Gregory S Day, Albert A Davis, Celeste M Karch, William W Seeley, Richard J Perrin, Rama K Koppisetti, Faris Shaikh, Argentina Lario Lago, Hilary W Heuer, Nupur Ghoshal, Audrey Gabelle, Bruce L Miller, Adam L Boxer, Randell J Bateman, Chihiro Sato
CSF tau microtubule-binding region identifies pathological changes in primary tauopathies. Nature medicine (2022)
Antoine Drieu, Siling Du, Steffen E Storck, Justin Rustenhoven, Zachary Papadopoulos, Taitea Dykstra, Fenghe Zhong, Kyungdeok Kim, Susan Blackburn, Tornike Mamuladze, Oscar Harari, Celeste M Karch, Randell J Bateman, Richard J Perrin, Martin Farlow, Jasmeer P Chhatwal, null null, Song Hu, Gwendalyn J Randolph, Igor Smirnov, Jonathan Kipnis
Parenchymal border macrophages regulate the flow dynamics of the cerebrospinal fluid. Nature 611 (7936) (2022)
Benjamin Caballero, Mathieu Bourdenx, Enrique Luengo, Antonio Diaz, Peter Dongmin Sohn, Xu Chen, Chao Wang, Yves R Juste, Susanne Wegmann, Bindi Patel, Zapporah T Young, Szu Yu Kuo, Jose Antonio Rodriguez-Navarro, Hao Shao, Manuela G López, Celeste M Karch, Alison Mary Goate, Jason E Gestwicki, Bradley T Hyman, Li Gan, Ana Maria Cuervo
Acetylated tau inhibits chaperone-mediated autophagy and promotes tau pathology propagation in mice. Nature communications 12 (1) (2021)
Nelly Joseph-Mathurin, Guoqiao Wang, Kejal Kantarci, Clifford R Jack, Eric McDade, Jason Hassenstab, Tyler M Blazey, Brian A Gordon, Yi Su, Gengsheng Chen, Parinaz Massoumzadeh, Russ C Hornbeck, Ricardo F Allegri, Beau M Ances, Sarah B Berman, Adam M Brickman, William S Brooks, David M Cash, Jasmeer P Chhatwal, Helena C Chui, Stephen Correia, Carlos Cruchaga, Martin R Farlow, Nick C Fox, Michael J Fulham, Bernardino Ghetti, Neill R Graff-Radford, Keith A Johnson, Celeste M Karch, Christoph Laske, Athene K W Lee, Johannes Levin, Colin L Masters, James M Noble, Antoinette O'Connor, Richard J Perrin, Gregory M Preboske, John M Ringman, Christopher C Rowe, Stephen Salloway, Andrew J Saykin, Peter R Schofield, Hiroyuki Shimada, Mikio Shoji, Kazushi Suzuki, Victor L Villemagne, Chengjie Xiong, Igor Yakushev, John C Morris, Randell J Bateman, Tammie L S Benzinger, null null
Longitudinal Accumulation of Cerebral Microhemorrhages in Dominantly Inherited Alzheimer Disease. Neurology 96 (12) (2021)
Sandro Da Mesquita, Zachary Papadopoulos, Taitea Dykstra, Logan Brase, Fabiana Geraldo Farias, Morgan Wall, Hong Jiang, Chinnappa Dilip Kodira, Kalil Alves de Lima, Jasmin Herz, Antoine Louveau, Dylan H Goldman, Andrea Francesca Salvador, Suna Onengut-Gumuscu, Emily Farber, Nisha Dabhi, Tatiana Kennedy, Mary Grace Milam, Wendy Baker, Igor Smirnov, Stephen S Rich, null null, Bruno A Benitez, Celeste M Karch, Richard J Perrin, Martin Farlow, Jasmeer P Chhatwal, David M Holtzman, Carlos Cruchaga, Oscar Harari, Jonathan Kipnis
Meningeal lymphatics affect microglia responses and anti-Aβ immunotherapy. Nature 593 (7858) (2021)
Fuhai Li, Abdallah Eteleeb, William Buchser, Guoqiao Wang, Chengjie Xiong, Philip Richard Orrin Payne, Eric McDade, Celeste M Karch, Oscar Harari, Carlos Cruchaga
Weakly activated core inflammation pathways were identified as a central signaling mechanism contributing to the chronic neurodegeneration in Alzheimer's disease. bioRxiv : the preprint server for biology (2021)
Yuetiva K Deming, Fabia Filipello, Francesca Cignarella, Claudia Cantoni, Simon Hsu, Robert Mikesell, Zeran Li, Jorge L Del-Aguila, Umber Dube, Fabiana Geraldo Farias, Joseph Bradley, John P Budde, Laura Ibañez, Maria Victoria Fernandez, Kaj Blennow, Henrik Zetterberg, Amanda J Heslegrave, Per Mårten Johansson, Johan Svensson, Bengt Nellgård, Alberto Lleo, Daniel Alcolea, Jordi Clarimón, Lorena Rami, José Luis Molinuevo, Marc Suarez-Calvet, Estrella Morenas-Rodríguez, Gernot Kleinberger, Michael Ewers, Oscar Harari, Christian Haass, Thomas J Brett, Bruno A Benitez, Celeste M Karch, Laura Piccio, Carlos Cruchaga
The MS4A gene cluster is a key modulator of soluble TREM2 and Alzheimer's disease risk. Science translational medicine 11 (505) (2020)
Nicolas R Barthélemy, Yan Li, Nelly Joseph-Mathurin, Brian A Gordon, Jason Hassenstab, Tammie L S Benzinger, Virginia Buckles, Anne M Fagan, Richard J Perrin, Alison Mary Goate, John C Morris, Celeste M Karch, Chengjie Xiong, Ricardo Allegri, Patricio Chrem Mendez, Sarah B Berman, Takeshi Ikeuchi, Hiroshi Mori, Hiroyuki Shimada, Mikio Shoji, Kazushi Suzuki, James Noble, Martin Farlow, Jasmeer P Chhatwal, Neill R Graff-Radford, Stephen Salloway, Peter R Schofield, Colin L Masters, Ralph N Martins, Antoinette O'Connor, Nick C Fox, Johannes Levin, Mathias Jucker, Audrey Gabelle, Sylvain Lehmann, Chihiro Sato, Randall J Bateman, Eric McDade, null null
A soluble phosphorylated tau signature links tau, amyloid and the evolution of stages of dominantly inherited Alzheimer's disease. Nature medicine 26 (3) (2020)
Israel Hernandez, Gabriel Luna, Jennifer N Rauch, Surya A Reis, Michel Giroux, Celeste M Karch, Daniel Boctor, Youssef E Sibih, Nadia J Storm, Antonio Diaz, Susmita Kaushik, Cezary Zekanowski, Alexander A Kang, Cassidy R Hinman, Vesna Cerovac, Elmer Guzman, Hongjun R Zhou, Stephen J Haggarty, Alison M Goate, Steven K Fisher, Ana M Cuervo, Kenneth S Kosik
A farnesyltransferase inhibitor activates lysosomes and reduces tau pathology in mice with tauopathy. Science translational medicine 11 (485) (2020)
Yin Xu, Shuqi Du, Jacob A Marsh, Kanta Horie, Chihiro Sato, Andrea Ballabio, Celeste M Karch, David M Holtzman, Hui Zheng
TFEB regulates lysosomal exocytosis of tau and its loss of function exacerbates tau pathology and spreading. Molecular psychiatry (2020)
Nicolai Franzmeier, Jinyi Ren, Alexander Damm, Gemma Monté-Rubio, Mercè Boada, Agustín Ruiz, Alfredo Ramirez, Frank Jessen, Emrah Düzel, Octavio Rodríguez Gómez, Tammie Benzinger, Alison Mary Goate, Celeste M Karch, Anne M Fagan, Eric McDade, Katharina Buerger, Johannes Levin, Marco Duering, Martin Dichgans, Marc Suárez-Calvet, Christian Haass, Brian A Gordon, Yen Ying Lim, Colin L Masters, Daniel Janowitz, Cihan Catak, Steffen Wolfsgruber, Michael Wagner, Esther Milz, Sonia Moreno-Grau, Stefan Teipel, Michel J Grothe, Ingo Kilimann, Martin Rossor, Nick Fox, Christoph Laske, Jasmeer Chhatwal, Peter Falkai, Matthias Brendel, Jae-Hong Lee, Annika Spottke, Henning Boecker, Frederic Brosseron, Klaus Fliessbach, Michael T Heneka, Peter Nestor, Oliver Peters, Manuel Fuentes, Felix Menne, Josef Priller, Eike J Spruth, Christiana Franke, Anja Schneider, Christine Westerteicher, Oliver Speck, Jens Wiltfang, Claudia Bartels, Miguel Ángel Araque Caballero, Coraline Metzger, Daniel Bittner, Stephen P Salloway, Adrian Danek, Jason Hassenstab, Igor Yakushev, Peter R Schofield, John C Morris, Randall J Bateman, Michael Ewers
The BDNFVal66Met SNP modulates the association between beta-amyloid and hippocampal disconnection in Alzheimer's disease. Molecular psychiatry 26 (2) (2019)
Ross W Paterson, Audrey Gabelle, Brendan P Lucey, Nicolas R Barthélemy, Claire A Leckey, Christophe Hirtz, Sylvain Lehmann, Chihiro Sato, Bruce W Patterson, Tim West, Kevin Yarasheski, Jonathan D Rohrer, Norelle C Wildburger, Jonathan M Schott, Celeste M Karch, Selina Wray, Timothy M Miller, Donald L Elbert, Henrik Zetterberg, Nick C Fox, Randall J Bateman
SILK studies - capturing the turnover of proteins linked to neurodegenerative diseases. Nature reviews. Neurology 15 (7) (2019)
Shan Jiang, Natalie Wen, Zeran Li, Umber Dube, Jorge Del Aguila, John P Budde, Rita Martinez, Simon Hsu, Maria V Fernandez, Nigel J Cairns, null null, null null, Oscar Harari, Carlos Cruchaga, Celeste M Karch
Integrative system biology analyses of CRISPR-edited iPSC-derived neurons and human brains reveal deficiencies of presynaptic signaling in FTLD and PSP. Translational psychiatry 8 (1) (2018)
Iris J Broce, Celeste M Karch, Natalie Wen, Chun C Fan, Yunpeng Wang, Chin Hong Tan, Naomi Kouri, Owen A Ross, Günter U Höglinger, Ulrich Muller, John Hardy, null null, Parastoo Momeni, Christopher P Hess, William P Dillon, Zachary A Miller, Luke W Bonham, Gil D Rabinovici, Howard J Rosen, Gerard D Schellenberg, Andre Franke, Tom H Karlsen, Jan Herman Veldink, Raffaele Ferrari, Jennifer S Yokoyama, Bruce L Miller, Ole A Andreassen, Anders M Dale, Rahul S Desikan, Leo P Sugrue
Immune-related genetic enrichment in frontotemporal dementia: An analysis of genome-wide association studies. PLoS medicine 15 (1) (2018)
Celeste M Karch, Damián Hernández, Jen-Chyong Wang, Jacob Marsh, Alex W Hewitt, Simon Hsu, Joanne Norton, Denise Levitch, Tamara Donahue, Wendy Sigurdson, Bernardino Ghetti, Martin Farlow, Jasmeer Chhatwal, Sarah Berman, Carlos Cruchaga, John C Morris, Randall J Bateman, null null, Alice Pébay, Alison M Goate
Human fibroblast and stem cell resource from the Dominantly Inherited Alzheimer Network. Alzheimer's research & therapy 10 (1) (2018)
Simon Hsu, Brian A Gordon, Russ Hornbeck, Joanne B Norton, Denise Levitch, Adia Louden, Ellen Ziegemeier, Robert Laforce, Jasmeer Chhatwal, Gregory S Day, Eric McDade, John C Morris, Anne M Fagan, Tammie L S Benzinger, Alison M Goate, Carlos Cruchaga, Randall J Bateman, null null, Celeste M Karch
Discovery and validation of autosomal dominant Alzheimer's disease mutations. Alzheimer's research & therapy 10 (1) (2018)
Luke W Bonham, Celeste M Karch, Chun-Chieh Fan, Chin Hong Tan, Ethan G Geier, Yunpeng Wang, Natalie Wen, Iris J Broce, Yi Li, Matthew J Barkovich, Raffaele Ferrari, John Hardy, Parastoo Momeni, Günter U Höglinger, Ulrich Müller, Christopher P Hess, Leo P Sugrue, William P Dillon, Gerard D Schellenberg, Bruce L Miller, Ole Andreas Andreassen, Anders M Dale, A James Barkovich, Jennifer S Yokoyama, Rahul S Desikan, null null, null null, null null
CXCR4 involvement in neurodegenerative diseases. Translational psychiatry 8 (1) (2018)
Rahul S Desikan, Chun-Chieh Fan, Yunpeng Wang, Andrew J Schork, Howard J Cabral, L Adrienne Cupples, Wesley K Thompson, Lilah Besser, Walter A Kukull, Dominic Holland, Chi-Hua Chen, James B Brewer, David S Karow, Karolina Kauppi, Aree Witoelar, Celeste M Karch, Luke W Bonham, Jennifer S Yokoyama, Howard J Rosen, Bruce L Miller, William P Dillon, David M Wilson, Christopher P Hess, Margaret Pericak-Vance, Jonathan L Haines, Lindsay A Farrer, Richard Mayeux, John Hardy, Alison M Goate, Bradley T Hyman, Gerard D Schellenberg, Linda K McEvoy, Ole A Andreassen, Anders M Dale
Genetic assessment of age-associated Alzheimer disease risk: Development and validation of a polygenic hazard score. PLoS medicine 14 (3) (2017)
Daniel L Kober, Jennifer M Alexander-Brett, Celeste M Karch, Carlos Cruchaga, Marco Colonna, Michael J Holtzman, Thomas J Brett
Neurodegenerative disease mutations in TREM2 reveal a functional surface and distinct loss-of-function mechanisms. eLife 5 (2016)
Monali Wakle-Prabagaran, Ramón A Lorca, Xiaofeng Ma, Susan J Stamnes, Chinwendu Amazu, Jordy J Hsiao, Celeste M Karch, Krzysztof L Hyrc, Michael E Wright, Sarah K England
BKCa channel regulates calcium oscillations induced by alpha-2-macroglobulin in human myometrial smooth muscle cells. Proceedings of the National Academy of Sciences of the United States of America 113 (16) (2016)

Celeste M Karch.css-eqlu8i{font-size:small;padding-left:4px;} (Celeste Karch, C M Karch)

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Celeste M Karch (Celeste Karch, C M Karch)