Nathan A Lack

Publication Activity (10 Years)

Years Active: 2021-2024
Publications (10 Years): 25

Top Topics

Benign Prostatic Hyperplasia

Radical Prostatectomy

Genome Wide Association Study

Top Venues

Nucleic acids research

Genome research

This page only lists publications with an associated author ORCID identifier.

Publications

Stacey E P Joosten, Sebastian Gregoricchio, Suzan Stelloo, Elif Yapıcı, Chia-Chi Flora Huang, Kerim Yavuz, Maria Christine Donaldson, Tunç Morova, Umut Berkay Altintas, Yongsoo Kim, Sander Canisius, Cathy B Moelans, Paul J van Diest, Gozde Korkmaz, Nathan A Lack, Michiel Vermeulen, Sabine C Linn, Wilbert Zwart
Estrogen receptor 1 chromatin profiling in human breast tumors reveals high inter-patient heterogeneity with enrichment of risk SNPs and enhancer activity at most-conserved regions. Genome research 34 (4) (2024)
Stacey E P Joosten, Sebastian Gregoricchio, Suzan Stelloo, Elif Yapıcı, Chia-Chi Flora Huang, Kerim Yavuz, Maria Christine Donaldson, Tunç Morova, Umut Berkay Altintas, Yongsoo Kim, Sander Canisius, Cathy B Moelans, Paul J van Diest, Gozde Korkmaz, Nathan A Lack, Michiel Vermeulen, Sabine C Linn, Wilbert Zwart
Estrogen receptor 1 chromatin profiling in human breast tumors reveals high inter-patient heterogeneity with enrichment of risk SNPs and enhancer activity at most-conserved regions. Genome research (2024)
Stacey E P Joosten, Sebastian Gregoricchio, Suzan Stelloo, Elif Yapıcı, Chia-Chi Flora Huang, Kerim Yavuz, Maria Christine Donaldson, Tunç Morova, Umut Berkay Altintas, Yongsoo Kim, Sander Canisius, Cathy B Moelans, Paul J van Diest, Gozde Korkmaz, Nathan A Lack, Michiel Vermeulen, Sabine C Linn, Wilbert Zwart
Estrogen receptor 1 chromatin profiling in human breast tumors reveals high inter-patient heterogeneity with enrichment of risk SNPs and enhancer activity at most-conserved regions. Genome research 34 (4) (2024)
Stacey E P Joosten, Sebastian Gregoricchio, Suzan Stelloo, Elif Yapıcı, Chia-Chi Flora Huang, Kerim Yavuz, Maria Christine Donaldson, Tunç Morova, Umut Berkay Altintas, Yongsoo Kim, Sander Canisius, Cathy B Moelans, Paul J van Diest, Gozde Korkmaz, Nathan A Lack, Michiel Vermeulen, Sabine C Linn, Wilbert Zwart
Estrogen receptor 1 chromatin profiling in human breast tumors reveals high inter-patient heterogeneity with enrichment of risk SNPs and enhancer activity at most-conserved regions. Genome research 34 (4) (2024)
Stacey E P Joosten, Sebastian Gregoricchio, Suzan Stelloo, Elif Yapıcı, Chia-Chi Flora Huang, Kerim Yavuz, Maria Christine Donaldson, Tunç Morova, Umut Berkay Altintas, Yongsoo Kim, Sander Canisius, Cathy B Moelans, Paul J van Diest, Gozde Korkmaz, Nathan A Lack, Michiel Vermeulen, Sabine C Linn, Wilbert Zwart
Estrogen receptor 1 chromatin profiling in human breast tumors reveals high inter-patient heterogeneity with enrichment of risk SNPs and enhancer activity at most-conserved regions. Genome research 34 (4) (2024)
Stacey E P Joosten, Sebastian Gregoricchio, Suzan Stelloo, Elif Yapıcı, Chia-Chi Flora Huang, Kerim Yavuz, Maria Christine Donaldson, Tunç Morova, Umut Berkay Altintas, Yongsoo Kim, Sander Canisius, Cathy B Moelans, Paul J van Diest, Gozde Korkmaz, Nathan A Lack, Michiel Vermeulen, Sabine C Linn, Wilbert Zwart
Estrogen receptor 1 chromatin profiling in human breast tumors reveals high inter-patient heterogeneity with enrichment of risk SNPs and enhancer activity at most-conserved regions. Genome research 34 (4) (2024)
Stacey E P Joosten, Sebastian Gregoricchio, Suzan Stelloo, Elif Yapıcı, Chia-Chi Flora Huang, Kerim Yavuz, Maria Christine Donaldson, Tunç Morova, Umut Berkay Altintas, Yongsoo Kim, Sander Canisius, Cathy B Moelans, Paul J van Diest, Gozde Korkmaz, Nathan A Lack, Michiel Vermeulen, Sabine C Linn, Wilbert Zwart
Estrogen receptor 1 chromatin profiling in human breast tumors reveals high inter-patient heterogeneity with enrichment of risk SNPs and enhancer activity at most-conserved regions. Genome research 34 (4) (2024)
Stacey E P Joosten, Sebastian Gregoricchio, Suzan Stelloo, Elif Yapıcı, Chia-Chi Flora Huang, Kerim Yavuz, Maria Christine Donaldson, Tunç Morova, Umut Berkay Altintas, Yongsoo Kim, Sander Canisius, Cathy B Moelans, Paul J van Diest, Gozde Korkmaz, Nathan A Lack, Michiel Vermeulen, Sabine C Linn, Wilbert Zwart
Estrogen receptor 1 chromatin profiling in human breast tumors reveals high inter-patient heterogeneity with enrichment of risk SNPs and enhancer activity at most-conserved regions. Genome research 34 (4) (2024)
Fan Zhang, Maitree Biswas, Shabnam Massah, Joseph Lee, Shreyas Lingadahalli, Samantha Wong, Christopher Wells, Jane Foo, Nabeel M Khan, Helene Morin, Neetu Saxena, Sonia H Y Kung, Bei Sun, Ana Karla Parra Nuñez, Christophe Sanchez, Novia Chan, Lauren Ung, Umut Berkay Altıntaş, Jennifer M Bui, Yuzhuo Wang, Ladan Fazli, Htoo Zarni Oo, Paul S Rennie, Nathan A Lack, Artem Cherkasov, Martin E Gleave, Jörg Gsponer, Nada Lallous
Dynamic phase separation of the androgen receptor and its coactivators key to regulate gene expression. Nucleic acids research 51 (1) (2023)
Tunc Morova, Yi Ding, Chia-Chi F Huang, Funda Sar, Tommer Schwarz, Claudia Giambartolomei, Sylvan C Baca, Dennis Grishin, Faraz Hach, Alexander Gusev, Matthew L Freedman, Bogdan Pasaniuc, Nathan A Lack
Optimized high-throughput screening of non-coding variants identified from genome-wide association studies. Nucleic acids research 51 (3) (2023)
Tunc Morova, Yi Ding, Chia-Chi F Huang, Funda Sar, Tommer Schwarz, Claudia Giambartolomei, Sylvan C Baca, Dennis Grishin, Faraz Hach, Alexander Gusev, Matthew L Freedman, Bogdan Pasaniuc, Nathan A Lack
Optimized high-throughput screening of non-coding variants identified from genome-wide association studies. Nucleic acids research 51 (3) (2023)
Özge Soylu-Eter, Zekiye Şeyma Sevinçli, Betül Ersoy, Bahar Hasanusta, Uğur Gatfar, Nathan A Lack, Burak Erman, Ahmet Gül, Hakan S Orer, Nilgün Karalı
5-Fluoro/(trifluoromethoxy)-2-indolinone derivatives with anti-interleukin-1 activity. Archiv der Pharmazie (2023)
Fan Zhang, Maitree Biswas, Shabnam Massah, Joseph Lee, Shreyas Lingadahalli, Samantha Wong, Christopher Wells, Jane Foo, Nabeel M Khan, Helene Morin, Neetu Saxena, Sonia H Y Kung, Bei Sun, Ana Karla Parra Nuñez, Christophe Sanchez, Novia Chan, Lauren Ung, Umut Berkay Altıntaş, Jennifer M Bui, Yuzhuo Wang, Ladan Fazli, Htoo Zarni Oo, Paul S Rennie, Nathan A Lack, Artem Cherkasov, Martin E Gleave, Jörg Gsponer, Nada Lallous
Dynamic phase separation of the androgen receptor and its coactivators key to regulate gene expression. Nucleic acids research 51 (1) (2023)
Tunc Morova, Yi Ding, Chia-Chi F Huang, Funda Sar, Tommer Schwarz, Claudia Giambartolomei, Sylvan C Baca, Dennis Grishin, Faraz Hach, Alexander Gusev, Matthew L Freedman, Bogdan Pasaniuc, Nathan A Lack
Optimized high-throughput screening of non-coding variants identified from genome-wide association studies. Nucleic acids research 51 (3) (2023)
Fan Zhang, Maitree Biswas, Shabnam Massah, Joseph Lee, Shreyas Lingadahalli, Samantha Wong, Christopher Wells, Jane Foo, Nabeel M Khan, Helene Morin, Neetu Saxena, Sonia H Y Kung, Bei Sun, Ana Karla Parra Nuñez, Christophe Sanchez, Novia Chan, Lauren Ung, Umut Berkay Altıntaş, Jennifer M Bui, Yuzhuo Wang, Ladan Fazli, Htoo Zarni Oo, Paul S Rennie, Nathan A Lack, Artem Cherkasov, Martin E Gleave, Jörg Gsponer, Nada Lallous
Dynamic phase separation of the androgen receptor and its coactivators key to regulate gene expression. Nucleic acids research 51 (1) (2023)
Adrianna A Mendes, Jiayun Lu, Harsimar B Kaur, Siqun L Zheng, Jianfeng Xu, Jessica Hicks, Adam B Weiner, Edward M Schaeffer, Ashley E Ross, Steven P Balk, Mary-Ellen Taplin, Nathan A Lack, Emirhan Tekoglu, Janielle P Maynard, Angelo M De Marzo, Emmanuel S Antonarakis, Karen S Sfanos, Corinne E Joshu, Eugene Shenderov, Tamara L Lotan
Association of B7-H3 expression with racial ancestry, immune cell density, and androgen receptor activation in prostate cancer. Cancer 128 (12) (2022)
Tunc Morova, Yi Ding, Chia-Chi F Huang, Funda Sar, Tommer Schwarz, Claudia Giambartolomei, Sylvan C Baca, Dennis Grishin, Faraz Hach, Alexander Gusev, Matthew L Freedman, Bogdan Pasaniuc, Nathan A Lack
Optimized high-throughput screening of non-coding variants identified from genome-wide association studies. Nucleic acids research (2022)
Alisan Kayabolen, Ugur Akcan, Doğancan Özturan, Hivda Ulbeği Polat, Gizem Nur Sahin, Nareg Pinarbasi Degirmenci, Canan Bayraktar, Gizem Soyler, Ehsan Sarayloo, Elif Nurtop, Berna Özer, Gülen Esken, Tayfun Barlas, Ismail Selim Yildirim, Ozlem Dogan, Sercin Karahuseyinoglu, Nathan A Lack, Mehmet Kaya, Cem Albayrak, Füsun Can, Ihsan Solaroglu, Tugba Bagcı-Önder
Protein Scaffold-Based Multimerization of Soluble ACE2 Efficiently Blocks SARS-CoV-2 Infection In Vitro and In Vivo. Advanced science (Weinheim, Baden-Wurttemberg, Germany) 9 (27) (2022)
Ozlem Yedier-Bayram, Bengul Gokbayrak, Alisan Kayabolen, Ali Cenk Aksu, Ayse Derya Cavga, Ahmet Cingöz, Ezgi Yagmur Kala, Goktug Karabiyik, Rauf Günsay, Beril Esin, Tunc Morova, Fırat Uyulur, Hamzah Syed, Martin Philpott, Adam P Cribbs, Sonia H Y Kung, Nathan A Lack, Tamer T Önder, Tugba Bagcı-Önder
EPIKOL, a chromatin-focused CRISPR/Cas9-based screening platform, to identify cancer-specific epigenetic vulnerabilities. Cell death & disease 13 (8) (2022)
Fan Zhang, Maitree Biswas, Shabnam Massah, Joseph Lee, Shreyas Lingadahalli, Samantha Wong, Christopher Wells, Jane Foo, Nabeel M Khan, Helene Morin, Neetu Saxena, Sonia H Y Kung, Bei Sun, Ana Karla Parra Nuñez, Christophe Sanchez, Novia Chan, Lauren Ung, Umut Berkay Altıntaş, Jennifer M Bui, Yuzhuo Wang, Ladan Fazli, Htoo Zarni Oo, Paul S Rennie, Nathan A Lack, Artem Cherkasov, Martin E Gleave, Jörg Gsponer, Nada Lallous
Dynamic phase separation of the androgen receptor and its coactivators key to regulate gene expression. Nucleic acids research (2022)
Tunc Morova, Yi Ding, Chia-Chi F Huang, Funda Sar, Tommer Schwarz, Claudia Giambartolomei, Sylvan C Baca, Dennis Grishin, Faraz Hach, Alexander Gusev, Matthew L Freedman, Bogdan Pasaniuc, Nathan A Lack
Optimized high-throughput screening of non-coding variants identified from genome-wide association studies. Nucleic acids research (2022)
Simon Linder, Marlous Hoogstraat, Suzan Stelloo, Nils Eickhoff, Karianne Schuurman, Hilda A de Barros, Maartje Alkemade, Elise M Bekers, Tesa M Severson, Joyce Sanders, Chia-Chi Flora Huang, Tunc Morova, Umut Berkay Altintas, Liesbeth Hoekman, Yongsoo Kim, Sylvan C Baca, Martin Sjostrom, Anniek Zaalberg, Dorine C Hintzen, Jeroen de Jong, Roelof J C Kluin, Iris de Rink, Claudia Giambartolomei, Ji-Heui Seo, Bogdan Pasaniuc, A F Maarten Altelaar, René H Medema, Felix Y Feng, Amina Zoubeidi, Matthew L Freedman, Lodewyk F A Wessels, Lisa M Butler, Nathan A Lack, Hendrik van der Poel, Andries M Bergman, Wilbert Zwart
Drug-Induced Epigenomic Plasticity Reprograms Circadian Rhythm Regulation to Drive Prostate Cancer toward Androgen Independence. Cancer discovery 12 (9) (2022)
Fatma Özgün, Zeynep Kaya, Tunç Morova, Bart Geverts, Tsion E Abraham, Adriaan B Houtsmuller, Martin E van Royen, Nathan A Lack
DNA binding alters ARv7 dimer interactions. Journal of cell science 134 (14) (2021)
Ceren Şeref, Omer Acar, Mert Kilic, Metin Vural, Yesim Saglican, Hilal Saraç, Bilgen Coşkun, Ümit İnce, Tarık Esen, Nathan A Lack
Histologically benign PI-RADS 4 and 5 lesions contain cancer-associated epigenetic alterations. The Prostate 82 (1) (2021)
Eric Leblanc, Fuqiang Ban, Ayse Derya Cavga, Sam Lawn, Chia-Chi Flora Huang, Sankar Mohan, Matthew E K Chang, Mark R Flory, Fariba Ghaidi, Shreyas Lingadahalli, Gang Chen, Ivan Pak Lok Yu, Hélène Morin, Nada Lallous, Martin E Gleave, Hisham Mohammed, Robert N Young, Paul S Rennie, Nathan A Lack, Artem Cherkasov
Development of 2-(5,6,7-Trifluoro-1H-Indol-3-yl)-quinoline-5-carboxamide as a Potent, Selective, and Orally Available Inhibitor of Human Androgen Receptor Targeting Its Binding Function-3 for the Treatment of Castration-Resistant Prostate Cancer. Journal of medicinal chemistry 64 (20) (2021)