Wilbert Zwart

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 54

Top Topics

Transcription Factor

Radical Prostatectomy

Top Venues

Genome research

Nature communications

Nucleic acids research

Nature genetics

This page only lists publications with an associated author ORCID identifier.

Publications

Ruben Schep, Max Trauernicht, Xabier Vergara, Anoek Friskes, Ben Morris, Sebastian Gregoricchio, Stefano G Manzo, Wilbert Zwart, Roderick L Beijersbergen, René H Medema, Bas van Steensel
Chromatin context-dependent effects of epigenetic drugs on CRISPR-Cas9 editing. Nucleic acids research 52 (15) (2024)
Ruben Schep, Max Trauernicht, Xabier Vergara, Anoek Friskes, Ben Morris, Sebastian Gregoricchio, Stefano G Manzo, Wilbert Zwart, Roderick L Beijersbergen, René H Medema, Bas van Steensel
Chromatin context-dependent effects of epigenetic drugs on CRISPR-Cas9 editing. Nucleic acids research (2024)
Ruben Schep, Max Trauernicht, Xabier Vergara, Anoek Friskes, Ben Morris, Sebastian Gregoricchio, Stefano G Manzo, Wilbert Zwart, Roderick L Beijersbergen, René H Medema, Bas van Steensel
Chromatin context-dependent effects of epigenetic drugs on CRISPR-Cas9 editing. Nucleic acids research 52 (15) (2024)
Duco Steven Koenis, Inkie J A Evers-van Gogh, Pieter B van Loenen, Wilbert Zwart, Eric Kalkhoven, Carlie J M de Vries
Nuclear receptor Nur77 and Yin-Yang 1 synergistically increase mitochondrial abundance and activity in macrophages. FEBS letters 598 (14) (2024)
Shuang G Zhao, Matthew Bootsma, Stanley Zhou, Raunak Shrestha, Thaidy Moreno-Rodriguez, Arian Lundberg, Chu Pan, Christopher Arlidge, James R Hawley, Adam Foye, Alana S Weinstein, Martin Sjostrom, Meng Zhang, Haolong Li, Lisa N Chesner, Nicholas R Rydzewski, Kyle T Helzer, Yue Shi, null null, Molly Lynch, Scott M Dehm, Joshua M Lang, Joshi J Alumkal, Housheng Hansen He, Alexander W Wyatt, Rahul R Aggarwal, Wilbert Zwart, Eric J Small, David A Quigley, Mathieu Lupien, Felix Y Feng
Integrated analyses highlight interactions between the three-dimensional genome and DNA, RNA and epigenomic alterations in metastatic prostate cancer. Nature genetics (2024)
Maisa N G van Genderen, Jeroen Kneppers, Anniek Zaalberg, Elise M Bekers, Andries M Bergman, Wilbert Zwart, Federica Eduati
Agent-based modeling of the prostate tumor microenvironment uncovers spatial tumor growth constraints and immunomodulatory properties. NPJ systems biology and applications 10 (1) (2024)
Maisa N G van Genderen, Jeroen Kneppers, Anniek Zaalberg, Elise M Bekers, Andries M Bergman, Wilbert Zwart, Federica Eduati
Agent-based modeling of the prostate tumor microenvironment uncovers spatial tumor growth constraints and immunomodulatory properties. NPJ systems biology and applications 10 (1) (2024)
Stacey E P Joosten, Sebastian Gregoricchio, Suzan Stelloo, Elif Yapıcı, Chia-Chi Flora Huang, Kerim Yavuz, Maria Christine Donaldson, Tunç Morova, Umut Berkay Altintas, Yongsoo Kim, Sander Canisius, Cathy B Moelans, Paul J van Diest, Gozde Korkmaz, Nathan A Lack, Michiel Vermeulen, Sabine C Linn, Wilbert Zwart
Estrogen receptor 1 chromatin profiling in human breast tumors reveals high inter-patient heterogeneity with enrichment of risk SNPs and enhancer activity at most-conserved regions. Genome research 34 (4) (2024)
Ruben Schep, Max Trauernicht, Xabier Vergara, Anoek Friskes, Ben Morris, Sebastian Gregoricchio, Stefano G Manzo, Wilbert Zwart, Roderick L Beijersbergen, René H Medema, Bas van Steensel
Chromatin context-dependent effects of epigenetic drugs on CRISPR-Cas9 editing. Nucleic acids research 52 (15) (2024)
Duco Steven Koenis, Inkie J A Evers-van Gogh, Pieter B van Loenen, Wilbert Zwart, Eric Kalkhoven, Carlie J M de Vries
Nuclear receptor Nur77 and Yin-Yang 1 synergistically increase mitochondrial abundance and activity in macrophages. FEBS letters 598 (14) (2024)
Shuang G Zhao, Matthew Bootsma, Stanley Zhou, Raunak Shrestha, Thaidy Moreno-Rodriguez, Arian Lundberg, Chu Pan, Christopher Arlidge, James R Hawley, Adam Foye, Alana S Weinstein, Martin Sjostrom, Meng Zhang, Haolong Li, Lisa N Chesner, Nicholas R Rydzewski, Kyle T Helzer, Yue Shi, null null, Molly Lynch, Scott M Dehm, Joshua M Lang, Joshi J Alumkal, Housheng Hansen He, Alexander W Wyatt, Rahul R Aggarwal, Wilbert Zwart, Eric J Small, David A Quigley, Mathieu Lupien, Felix Y Feng
Integrated analyses highlight interactions between the three-dimensional genome and DNA, RNA and epigenomic alterations in metastatic prostate cancer. Nature genetics 56 (8) (2024)
Stacey E P Joosten, Sebastian Gregoricchio, Suzan Stelloo, Elif Yapıcı, Chia-Chi Flora Huang, Kerim Yavuz, Maria Christine Donaldson, Tunç Morova, Umut Berkay Altintas, Yongsoo Kim, Sander Canisius, Cathy B Moelans, Paul J van Diest, Gozde Korkmaz, Nathan A Lack, Michiel Vermeulen, Sabine C Linn, Wilbert Zwart
Estrogen receptor 1 chromatin profiling in human breast tumors reveals high inter-patient heterogeneity with enrichment of risk SNPs and enhancer activity at most-conserved regions. Genome research (2024)
Maisa N G van Genderen, Jeroen Kneppers, Anniek Zaalberg, Elise M Bekers, Andries M Bergman, Wilbert Zwart, Federica Eduati
Agent-based modeling of the prostate tumor microenvironment uncovers spatial tumor growth constraints and immunomodulatory properties. NPJ systems biology and applications 10 (1) (2024)
Javier Carmona, Elena Chavarria, Kate Donoghue, Christina von Gertten, Petra Oberrauch, Emma Pailler, Giovanni Scoazec, Ruud Weijer, Judith Balmaña, Irene Brana, Cinzia Brunelli, Suzette Delaloge, Marc Deloger, Pierre Delpy, Ingemar Ernberg, Rebecca C Fitzgerald, Elena Garralda, Martin Lablans, Janne Lehtiö, Carlos Lopez, Maialen Fernández, Rosalba Miceli, Paolo G Nuciforo, Raquel Perez-Lopez, Elena Provenzano, Marjanka K Schmidt, Cesar Serrano, Neeltje Steeghs, David Tamborero, Valtteri Wirta, Richard D Baird, Karen Barker, Fabrice Barlesi, Michael Baumann, Jonas Bergh, Filippo G De Braud, Karim Fizazi, Stefan Fröhling, Alejandro Piris-Giménez, Kenneth Seamon, Michiel S Van Der Heijden, Wilbert Zwart, Josep Tabernero
Cancer Core Europe: Leveraging Institutional Synergies to Advance Oncology Research and Care Globally. Cancer discovery 14 (7) (2024)
Shuang G Zhao, Matthew Bootsma, Stanley Zhou, Raunak Shrestha, Thaidy Moreno-Rodriguez, Arian Lundberg, Chu Pan, Christopher Arlidge, James R Hawley, Adam Foye, Alana S Weinstein, Martin Sjostrom, Meng Zhang, Haolong Li, Lisa N Chesner, Nicholas R Rydzewski, Kyle T Helzer, Yue Shi, null null, Molly Lynch, Scott M Dehm, Joshua M Lang, Joshi J Alumkal, Housheng Hansen He, Alexander W Wyatt, Rahul R Aggarwal, Wilbert Zwart, Eric J Small, David A Quigley, Mathieu Lupien, Felix Y Feng
Integrated analyses highlight interactions between the three-dimensional genome and DNA, RNA and epigenomic alterations in metastatic prostate cancer. Nature genetics 56 (8) (2024)
Stacey E P Joosten, Sebastian Gregoricchio, Suzan Stelloo, Elif Yapıcı, Chia-Chi Flora Huang, Kerim Yavuz, Maria Christine Donaldson, Tunç Morova, Umut Berkay Altintas, Yongsoo Kim, Sander Canisius, Cathy B Moelans, Paul J van Diest, Gozde Korkmaz, Nathan A Lack, Michiel Vermeulen, Sabine C Linn, Wilbert Zwart
Estrogen receptor 1 chromatin profiling in human breast tumors reveals high inter-patient heterogeneity with enrichment of risk SNPs and enhancer activity at most-conserved regions. Genome research 34 (4) (2024)
Stacey E P Joosten, Sebastian Gregoricchio, Suzan Stelloo, Elif Yapıcı, Chia-Chi Flora Huang, Kerim Yavuz, Maria Christine Donaldson, Tunç Morova, Umut Berkay Altintas, Yongsoo Kim, Sander Canisius, Cathy B Moelans, Paul J van Diest, Gozde Korkmaz, Nathan A Lack, Michiel Vermeulen, Sabine C Linn, Wilbert Zwart
Estrogen receptor 1 chromatin profiling in human breast tumors reveals high inter-patient heterogeneity with enrichment of risk SNPs and enhancer activity at most-conserved regions. Genome research 34 (4) (2024)
Stacey E P Joosten, Sebastian Gregoricchio, Suzan Stelloo, Elif Yapıcı, Chia-Chi Flora Huang, Kerim Yavuz, Maria Christine Donaldson, Tunç Morova, Umut Berkay Altintas, Yongsoo Kim, Sander Canisius, Cathy B Moelans, Paul J van Diest, Gozde Korkmaz, Nathan A Lack, Michiel Vermeulen, Sabine C Linn, Wilbert Zwart
Estrogen receptor 1 chromatin profiling in human breast tumors reveals high inter-patient heterogeneity with enrichment of risk SNPs and enhancer activity at most-conserved regions. Genome research 34 (4) (2024)
Shuang G Zhao, Matthew Bootsma, Stanley Zhou, Raunak Shrestha, Thaidy Moreno-Rodriguez, Arian Lundberg, Chu Pan, Christopher Arlidge, James R Hawley, Adam Foye, Alana S Weinstein, Martin Sjostrom, Meng Zhang, Haolong Li, Lisa N Chesner, Nicholas R Rydzewski, Kyle T Helzer, Yue Shi, null null, Molly Lynch, Scott M Dehm, Joshua M Lang, Joshi J Alumkal, Housheng Hansen He, Alexander W Wyatt, Rahul R Aggarwal, Wilbert Zwart, Eric J Small, David A Quigley, Mathieu Lupien, Felix Y Feng
Integrated analyses highlight interactions between the three-dimensional genome and DNA, RNA and epigenomic alterations in metastatic prostate cancer. Nature genetics 56 (8) (2024)
Javier Carmona, Elena Chavarria, Kate Donoghue, Christina von Gertten, Petra Oberrauch, Emma Pailler, Giovanni Scoazec, Ruud Weijer, Judith Balmaña, Irene Brana, Cinzia Brunelli, Suzette Delaloge, Marc Deloger, Pierre Delpy, Ingemar Ernberg, Rebecca C Fitzgerald, Elena Garralda, Martin Lablans, Janne Lehtiö, Carlos Lopez, Maialen Fernández, Rosalba Miceli, Paolo G Nuciforo, Raquel Perez-Lopez, Elena Provenzano, Marjanka K Schmidt, Cesar Serrano, Neeltje Steeghs, David Tamborero, Valtteri Wirta, Richard D Baird, Karen Barker, Fabrice Barlesi, Michael Baumann, Jonas Bergh, Filippo G De Braud, Karim Fizazi, Stefan Fröhling, Alejandro Piris-Giménez, Kenneth Seamon, Michiel S Van Der Heijden, Wilbert Zwart, Josep Tabernero
Cancer Core Europe: Leveraging Institutional Synergies to Advance Oncology Research and Care Globally. Cancer discovery (2024)
Ruben Schep, Max Trauernicht, Xabier Vergara, Anoek Friskes, Ben Morris, Sebastian Gregoricchio, Stefano G Manzo, Wilbert Zwart, Roderick L Beijersbergen, René H Medema, Bas van Steensel
Chromatin context-dependent effects of epigenetic drugs on CRISPR-Cas9 editing. Nucleic acids research (2024)
Stacey E P Joosten, Sebastian Gregoricchio, Suzan Stelloo, Elif Yapıcı, Chia-Chi Flora Huang, Kerim Yavuz, Maria Christine Donaldson, Tunç Morova, Umut Berkay Altintas, Yongsoo Kim, Sander Canisius, Cathy B Moelans, Paul J van Diest, Gozde Korkmaz, Nathan A Lack, Michiel Vermeulen, Sabine C Linn, Wilbert Zwart
Estrogen receptor 1 chromatin profiling in human breast tumors reveals high inter-patient heterogeneity with enrichment of risk SNPs and enhancer activity at most-conserved regions. Genome research 34 (4) (2024)
Stacey E P Joosten, Sebastian Gregoricchio, Suzan Stelloo, Elif Yapıcı, Chia-Chi Flora Huang, Kerim Yavuz, Maria Christine Donaldson, Tunç Morova, Umut Berkay Altintas, Yongsoo Kim, Sander Canisius, Cathy B Moelans, Paul J van Diest, Gozde Korkmaz, Nathan A Lack, Michiel Vermeulen, Sabine C Linn, Wilbert Zwart
Estrogen receptor 1 chromatin profiling in human breast tumors reveals high inter-patient heterogeneity with enrichment of risk SNPs and enhancer activity at most-conserved regions. Genome research 34 (4) (2024)
Stacey E P Joosten, Sebastian Gregoricchio, Suzan Stelloo, Elif Yapıcı, Chia-Chi Flora Huang, Kerim Yavuz, Maria Christine Donaldson, Tunç Morova, Umut Berkay Altintas, Yongsoo Kim, Sander Canisius, Cathy B Moelans, Paul J van Diest, Gozde Korkmaz, Nathan A Lack, Michiel Vermeulen, Sabine C Linn, Wilbert Zwart
Estrogen receptor 1 chromatin profiling in human breast tumors reveals high inter-patient heterogeneity with enrichment of risk SNPs and enhancer activity at most-conserved regions. Genome research 34 (4) (2024)
Duco Steven Koenis, Inkie J A Evers-van Gogh, Pieter B van Loenen, Wilbert Zwart, Eric Kalkhoven, Carlie J M de Vries
Nuclear receptor Nur77 and Yin-Yang 1 synergistically increase mitochondrial abundance and activity in macrophages. FEBS letters (2024)
Sebastian Gregoricchio, Wilbert Zwart
snHiC : a complete and simplified snakemake pipeline for grouped Hi-C data analysis. Bioinformatics advances 3 (1) (2023)
Stefan Prekovic, Wilbert Zwart
Inhibiting the Glucocorticoid Receptor to Enhance Chemotherapy Response. Journal of clinical oncology : official journal of the American Society of Clinical Oncology (2023)
Seham Elabd, Eleonora Pauletto, Valeria Solozobova, Nils Eickhoff, Nuno Padrao, Wilbert Zwart, Christine Blattner
TRIM25 targets p300 for degradation. Life science alliance 6 (12) (2023)
Isabel Mayayo-Peralta, Donna O Debets, Stefan Prekovic, Karianne Schuurman, Suzanne Beerthuijzen, Mathilde Almekinders, Joyce Sanders, Cathy B Moelans, Sandra Saleiro, Jelle Wesseling, Paul J van Diest, Rui M Henrique, Carmen Jerónimo, A F Maarten Altelaar, Wilbert Zwart
Proteomics on malignant pleural effusions reveals ERα loss in metastatic breast cancer associates with SGK1-NDRG1 deregulation. Molecular oncology (2023)
Selçuk Yavuz, Hélène Kabbech, Jente van Staalduinen, Simon Linder, Wiggert A van Cappellen, Alex L Nigg, Tsion E Abraham, Johan A Slotman, Marti Quevedo, Raymond A Poot, Wilbert Zwart, Martin E van Royen, Frank G Grosveld, Ihor Smal, Adriaan B Houtsmuller
Compartmentalization of androgen receptors at endogenous genes in living cells. Nucleic acids research (2023)
Isabel Mayayo-Peralta, Sebastian Gregoricchio, Karianne Schuurman, Selçuk Yavuz, Anniek Zaalberg, Aleksandar Kojic, Nina Abbott, Bart Geverts, Suzanne Beerthuijzen, Joseph Siefert, Tesa M Severson, Martijn van Baalen, Liesbeth Hoekman, Cor Lieftink, Maarten Altelaar, Roderick L Beijersbergen, Adriaan B Houtsmuller, Stefan Prekovic, Wilbert Zwart
PAXIP1 and STAG2 converge to maintain 3D genome architecture and facilitate promoter/enhancer contacts to enable stress hormone-dependent transcription. Nucleic acids research (2023)
Margot Passier, Maisa N G van Genderen, Anniek Zaalberg, Jeroen Kneppers, Elise M Bekers, Andries M Bergman, Wilbert Zwart, Federica Eduati
Exploring the Onset and Progression of Prostate Cancer through a Multicellular Agent-based Model. Cancer research communications 3 (8) (2023)
Giacomo Grillo, Tina Keshavarzian, Simon Linder, Christopher Arlidge, Lisanne Mout, Ankita Nand, Mona Teng, Aditi Qamra, Stanley Zhou, Ken J Kron, Alex Murison, James R Hawley, Michael Fraser, Theodorus H Van der Kwast, Ganesh V Raj, Housheng Hansen He, Wilbert Zwart, Mathieu Lupien
Transposable elements are co-opted as oncogenic regulatory elements by lineage-specific transcription factors in prostate cancer. Cancer discovery (2023)
Dorien Clarisse, Stefan Prekovic, Philip Vlummens, Eleni Staessens, Karlien Van Wesemael, Jonathan Thommis, Daria Fijalkowska, Guillaume Acke, Wilbert Zwart, Ilse M Beck, Fritz Offner, Karolien De Bosscher
Crosstalk between glucocorticoid and mineralocorticoid receptors boosts glucocorticoid-induced killing of multiple myeloma cells. Cellular and molecular life sciences : CMLS 80 (9) (2023)
Stefan Prekovic, Theofilos Chalkiadakis, Merel Roest, Daniel Roden, Catrin Lutz, Karianne Schuurman, Mark Opdam, Liesbeth Hoekman, Nina Abbott, Tanja Tesselaar, Maliha Wajahat, Amy R Dwyer, Isabel Mayayo-Peralta, Gabriela Vilas Bôas Gomez, A F Maarten Altelaar, Roderick Beijersbergen, Gyorffy Balazs, Leonie Young, Sabine Linn, Jos Jonkers, Wayne D Tilley, Theresa E Hickey, Damir Varešlija, Alexander Swarbrick, Wilbert Zwart
Luminal breast cancer identity is determined by loss of glucocorticoid receptor activity. EMBO molecular medicine (2023)
Dario Zimmerli, Chiara S Brambillasca, Francien Talens, Jinhyuk Bhin, Renske Linstra, Lou Romanens, Arkajyoti Bhattacharya, Stacey E P Joosten, Ana Moises Da Silva, Nuno Padrao, Max D Wellenstein, Kelly Kersten, Mart de Boo, Maurits Roorda, Linda Henneman, Roebi de Bruijn, Stefano Annunziato, Eline van der Burg, Anne Paulien Drenth, Catrin Lutz, Theresa Endres, Marieke van de Ven, Martin Eilers, Lodewyk F A Wessels, Karin E de Visser, Wilbert Zwart, Rudolf S N Fehrmann, Marcel A T M van Vugt, Jos Jonkers
MYC promotes immune-suppression in triple-negative breast cancer via inhibition of interferon signaling. Nature communications 13 (1) (2022)
Nils Eickhoff, Andries M Bergman, Wilbert Zwart
Homing in on a Moving Target: Androgen Receptor Cistromic Plasticity in Prostate Cancer. Endocrinology 163 (11) (2022)
Jeroen Kneppers, Tesa M Severson, Joseph C Siefert, Pieter Schol, Stacey E P Joosten, Ivan Pak Lok Yu, Chia-Chi Flora Huang, Tunç Morova, Umut Berkay Altintas, Claudia Giambartolomei, Ji-Heui Seo, Sylvan C Baca, Isa Carneiro, Eldon Emberly, Bogdan Pasaniuc, Carmen Jerónimo, Rui M Henrique, Matthew L Freedman, Lodewyk F A Wessels, Nathan A Lack, Andries M Bergman, Wilbert Zwart
Extensive androgen receptor enhancer heterogeneity in primary prostate cancers underlies transcriptional diversity and metastatic potential. Nature communications 13 (1) (2022)
Sylvan C Baca, Cassandra Singler, Soumya Zacharia, Ji-Heui Seo, Tunc Morova, Faraz Hach, Yi Ding, Tommer Schwarz, Chia-Chi Flora Huang, Jacob Anderson, André P Fay, Cynthia Kalita, Stefan Groha, Mark M Pomerantz, Victoria Wang, Simon Linder, Christopher J Sweeney, Wilbert Zwart, Nathan A Lack, Bogdan Pasaniuc, David Y Takeda, Alexander Gusev, Matthew L Freedman
Genetic determinants of chromatin reveal prostate cancer risk mediated by context-dependent gene regulation. Nature genetics 54 (9) (2022)
Joana Silva, Ferhat Alkan, Sofia Ramalho, Goda Snieckute, Stefan Prekovic, Ana Krotenberg Garcia, Santiago Hernández-Pérez, Rob van der Kammen, Danielle Barnum, Liesbeth Hoekman, Maarten Altelaar, Wilbert Zwart, Saskia Jacoba Elisabeth Suijkerbuijk, Simon Bekker-Jensen, William James Faller
Ribosome impairment regulates intestinal stem cell identity via ZAKɑ activation. Nature communications 13 (1) (2022)
Simon Linder, Marlous Hoogstraat, Suzan Stelloo, Nils Eickhoff, Karianne Schuurman, Hilda A de Barros, Maartje Alkemade, Elise M Bekers, Tesa M Severson, Joyce Sanders, Chia-Chi Flora Huang, Tunc Morova, Umut Berkay Altintas, Liesbeth Hoekman, Yongsoo Kim, Sylvan C Baca, Martin Sjostrom, Anniek Zaalberg, Dorine C Hintzen, Jeroen de Jong, Roelof J C Kluin, Iris de Rink, Claudia Giambartolomei, Ji-Heui Seo, Bogdan Pasaniuc, A F Maarten Altelaar, René H Medema, Felix Y Feng, Amina Zoubeidi, Matthew L Freedman, Lodewyk F A Wessels, Lisa M Butler, Nathan A Lack, Hendrik van der Poel, Andries M Bergman, Wilbert Zwart
Drug-Induced Epigenomic Plasticity Reprograms Circadian Rhythm Regulation to Drive Prostate Cancer toward Androgen Independence. Cancer discovery 12 (9) (2022)
Martin Sjostrom, Shuang G Zhao, Samuel Levy, Meng Zhang, Yuhong Ning, Raunak Shrestha, Arian Lundberg, Cameron Herberts, Adam Foye, Rahul R Aggarwal, Junjie T Hua, Haolong Li, Anna Bergamaschi, Corinne Maurice-Dror, Ashutosh Maheshwari, Sujun Chen, Sarah W S Ng, Michael Fraser, Jessica Petricca, Michael Fraser, Lisa Chesner, Marc D Perry, Thaidy Moreno-Rodriguez, William S Chen, Joshi J Alumkal, Jonathan Chou, Alicia K Morgans, Tomasz M Beer, George V Thomas, Martin Gleave, Paul Lloyd, Tierney Phillips, Erin McCarthy, Michael C Haffner, Amina Zoubeidi, Matti Annala, Robert E Reiter, Matthew B Rettig, Owen N Witte, Lawrence Fong, Rohit Bose, Franklin W Huang, Joshua M Lang, Anders Bjartell, Nupam P Mahajan, Primo N Lara, Christopher P Evans, Phuoc T Tran, Edwin M Posadas, Chuan He, Xiao-Long Cui, Jiaoti Huang, Wilbert Zwart, Luke A Gilbert, Christopher A Maher, Paul C Boutros, Kim N Chi, Alan Ashworth, Eric J Small, Housheng Hansen He, Alexander W Wyatt, David A Quigley, Felix Y Feng
The 5-Hydroxymethylcytosine Landscape of Prostate Cancer. Cancer research 82 (21) (2022)
Alastair Davies, Shaghayegh Nouruzi, Dwaipayan Ganguli, Takeshi Namekawa, Daksh Thaper, Simon Linder, Fatih Karaoğlanoğlu, Meltem E Omur, Soojin Kim, Maxim Kobelev, Sahil Kumar, Olena Sivak, Chiara Bostock, Jennifer Bishop, Marlous Hoogstraat, Amina Talal, Suzan Stelloo, Henk van der Poel, Andries M Bergman, Musaddeque Ahmed, Ladan Fazli, Zhenlin Huang, Wayne D Tilley, David Goodrich, Felix Y Feng, Martin Gleave, Housheng Hansen He, Faraz Hach, Wilbert Zwart, Himisha Beltran, Luke A Selth, Amina Zoubeidi
An androgen receptor switch underlies lineage infidelity in treatment-resistant prostate cancer. Nature cell biology 23 (9) (2021)
Tiziano Bernasocchi, Geniver El Tekle, Marco Bolis, Azzurra Mutti, Arianna Vallerga, Laura P Brandt, Filippo Spriano, Tanya Svinkina, Marita Zoma, Valentina Ceserani, Anna Rinaldi, Hana Janouskova, Daniela Bossi, Manuela Cavalli, Simone Mosole, Roger Geiger, Ze Dong, Cai-Guang Yang, Domenico Albino, Andrea Rinaldi, Peter Schraml, Simon Linder, Giuseppina M Carbone, Andrea Alimonti, Francesco Bertoni, Holger Moch, Steven A Carr, Wilbert Zwart, Marianna Kruithof de Julio, Mark A Rubin, Namrata D Udeshi, Jean-Philippe P Theurillat
Dual functions of SPOP and ERG dictate androgen therapy responses in prostate cancer. Nature communications 12 (1) (2021)
Stefan Prekovic, Karianne Schuurman, Isabel Mayayo-Peralta, Anna G Manjón, Mark Buijs, Selçuk Yavuz, Max D Wellenstein, Alejandro Barrera, Kim Monkhorst, Anne Huber, Ben Morris, Cor Lieftink, Theofilos Chalkiadakis, Ferhat Alkan, Joana Silva, Balázs Győrffy, Liesbeth Hoekman, Bram van den Broek, Hans Teunissen, Donna O Debets, Tesa Severson, Jos Jonkers, Timothy E Reddy, Karin E de Visser, William James Faller, Roderick L Beijersbergen, Maarten Altelaar, Elzo de Wit, Rene Medema, Wilbert Zwart
Glucocorticoid receptor triggers a reversible drug-tolerant dormancy state with acquired therapeutic vulnerabilities in lung cancer. Nature communications 12 (1) (2021)
Ayesha A Shafi, Chris M McNair, Jennifer J McCann, Mohammed Alshalalfa, Anton Shostak, Tesa M Severson, Yanyun Zhu, Andries M Bergman, Nicolas Gordon, Amy C Mandigo, Saswati N Chand, Peter Gallagher, Emanuela Dylgjeri, Talya S Laufer, Irina A Vasilevskaya, Matthew J Schiewer, Michael Brunner, Felix Y Feng, Wilbert Zwart, Beatrice Knudsen
The circadian cryptochrome, CRY1, is a pro-tumorigenic factor that rhythmically modulates DNA repair. Nature communications 12 (1) (2021)
Theresa E Hickey, Luke A Selth, Kee Ming Chia, Geraldine Laven-Law, Heloisa H Milioli, Daniel Lee Roden, Shalini Jindal, Mun Hui, Jessica Finlay-Schultz, Esmaeil Ebrahimie, Stephen N Birrell, Suzan Stelloo, Richard Iggo, Sarah Alexandrou, C Elizabeth Caldon, Tarek M Abdel-Fatah, Ian O Ellis, Wilbert Zwart, Carlo Palmieri, Carol A Sartorius, Alexander Swarbrick, Elgene Lim, Jason S Carroll, Wayne D Tilley
The androgen receptor is a tumor suppressor in estrogen receptor-positive breast cancer. Nature medicine 27 (2) (2021)
Meixia Che, Aashi Chaturvedi, Sarah A Munro, Samuel P Pitzen, Alexander L Ling, Weijie Zhang, Josh Mentzer, Sheng Yu Ku, Loredana Puca, Yanyun Zhu, Andries M Bergman, Tesa M Severson, Colleen Forster, Yuzhen Liu, Jacob Hildebrand, Mark Daniel, Ting-You Wang, Luke A Selth, Theresa E Hickey, Amina Zoubeidi, Martin Gleave, Rohan Bareja, Andrea Sboner, Wayne D Tilley, Jason S Carroll, Winston Tan, Manish Kohli, Rendong Yang, Andrew C Hsieh, Paari Murugan, Wilbert Zwart, Himisha Beltran, Rong Stephanie Huang, Scott M Dehm
Opposing transcriptional programs of KLF5 and AR emerge during therapy for advanced prostate cancer. Nature communications 12 (1) (2021)
Tesa M Severson, Yanyun Zhu, Angelo M De Marzo, Tracy Jones, Jonathan W Simons, William G Nelson, Srinivasan Yegnasubramanian, Matthew L Freedman, Lodewyk Wessels, Andries M Bergman, Michael C Haffner, Wilbert Zwart
Epigenetic and transcriptional analysis reveals a core transcriptional program conserved in clonal prostate cancer metastases. Molecular oncology 15 (7) (2021)
Bianca Cioni, Anniek Zaalberg, Judy R van Beijnum, Monique H M Melis, Johan van Burgsteden, Mauro J Muraro, Erik Hooijberg, Dennis Peters, Ingrid Hofland, Yoni Lubeck, Jeroen de Jong, Joyce Sanders, Judith Vivié, Henk G van der Poel, Jan Paul de Boer, Arjan W Griffioen, Wilbert Zwart, Andries M Bergman
Androgen receptor signalling in macrophages promotes TREM-1-mediated prostate cancer cell line migration and invasion. Nature communications 11 (1) (2020)
Mark M Pomerantz, Xintao Qiu, Yanyun Zhu, David Y Takeda, Wenting Pan, Sylvan C Baca, Alexander Gusev, Keegan D Korthauer, Tesa M Severson, Gavin Ha, Srinivas R Viswanathan, Ji-Heui Seo, Holly M Nguyen, Baohui Zhang, Bogdan Pasaniuc, Claudia Giambartolomei, Sarah A Alaiwi, Connor A Bell, Edward P O'Connor, Matthew S Chabot, David R Stillman, Rosina Lis, Alba Font-Tello, Lewyn Li, Paloma Cejas, Andries M Bergman, Joyce Sanders, Henk G van der Poel, Simon A Gayther, Kate Lawrenson, Marcos A S Fonseca, Jessica Reddy, Rosario I Corona, Gleb Martovetsky, Brian Egan, Toni K Choueiri, Leigh Ellis, Isla P Garraway, Gwo-Shu Mary Lee, Eva Corey, Henry W Long, Wilbert Zwart, Matthew L Freedman
Prostate cancer reactivates developmental epigenomic programs during metastatic progression. Nature genetics 52 (8) (2020)
Sander Al Palit, Daniel Vis, Suzan Stelloo, Cor Lieftink, Stefan Prekovic, Elise Bekers, Ingrid Hofland, Tonći Šuštić, Liesanne Wolters, Roderick Beijersbergen, Andries M Bergman, Balázs Győrffy, Lodewyk Fa Wessels, Wilbert Zwart, Michiel S van der Heijden
TLE3 loss confers AR inhibitor resistance by facilitating GR-mediated human prostate cancer cell growth. eLife 8 (2019)
Dinja T Kruger, Xanthippi Alexi, Mark Opdam, Karianne Schuurman, Leonie Voorwerk, Joyce Sanders, Vincent van der Noort, Epie Boven, Wilbert Zwart, Sabine C Linn
IGF-1R pathway activation as putative biomarker for linsitinib therapy to revert tamoxifen resistance in ER-positive breast cancer. International journal of cancer 146 (8) (2019)
Abhishek A Singh, Karianne Schuurman, Ekaterina Nevedomskaya, Suzan Stelloo, Simon Linder, Marjolein Droog, Yongsoo Kim, Joyce Sanders, Henk van der Poel, Andries M Bergman, Lodewyk Fa Wessels, Wilbert Zwart
Optimized ChIP-seq method facilitates transcription factor profiling in human tumors. Life science alliance 2 (1) (2018)