Olga G Troyanskaya (Olga Troyanskaya)

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 35

Top Topics

Chronic Obstructive Pulmonary Disease

Binding Protein

Genome Wide Association

Top Venues

Nature genetics

Nature computational science

Science translational medicine

This page only lists publications with an associated author ORCID identifier.

Publications

Tavis J Reed, Matthew D Tyl, Alicja Tadych, Olga G Troyanskaya, Ileana M Cristea
Tapioca: a platform for predicting de novo protein-protein interactions in dynamic contexts. Nature methods 21 (3) (2024)
Aviya Litman, Natalie Sauerwald, LeeAnne Green Snyder, Jennifer H Foss-Feig, Christopher Y Park, Yun Hao, Ilan Dinstein, Chandra L Theesfeld, Olga G Troyanskaya
Decomposition of phenotypic heterogeneity in autism reveals distinct and coherent genetic programs. medRxiv : the preprint server for health sciences (2024)
Tavis J Reed, Matthew D Tyl, Alicja Tadych, Olga G Troyanskaya, Ileana M Cristea
Tapioca: a platform for predicting de novo protein-protein interactions in dynamic contexts. Nature methods 21 (3) (2024)
Nick Shrine, Anna L Guyatt, A Mesut Erzurumluoglu, Victoria E Jackson, Brian D Hobbs, Carl A Melbourne, Chiara Batini, Katherine A Fawcett, Kijoung Song, Phuwanat Sakornsakolpat, Xingnan Li, Ruth Boxall, Nicola F Reeve, Ma'en Obeidat, Jing Hua Zhao, Matthias Wielscher, null null, Stefan Weiss, Katherine A Kentistou, James P Cook, Benjamin B Sun, Jian Zhou, Jennie Hui, Stefan Karrasch, Medea Imboden, Sarah E Harris, Jonathan Marten, Stefan Enroth, Shona M Kerr, Ida Surakka, Veronique Vitart, Terho Lehtimäki, Richard J Allen, Per S Bakke, Terri H Beaty, Eugene R Bleecker, Yohan Bosse, Corry-Anke Brandsma, Zhengming Chen, James D Crapo, John Danesh, Dawn L DeMeo, Frank Dudbridge, Ralf Ewert, Christian Gieger, Amund Gulsvik, Anna L Hansell, Ke Hao, Joshua D Hoffman, John E Hokanson, Georg Homuth, Peter K Joshi, Philippe Joubert, Claudia Langenberg, Xuan Li, Liming Li, Kuang Lin, Lars Lind, Nicholas Locantore, Jian'an Luan, Anubha Mahajan, Joseph C Maranville, Alison D Murray, David C Nickle, Richard Packer, Margaret M Parker, Megan L Paynton, David J Porteous, Dmitry Prokopenko, Dandi Qiao, Rajesh Rawal, Heiko Runz, Ian Sayers, Don D Sin, Blair Hamilton Smith, María Soler Artigas, David Sparrow, Ruth Tal-Singer, Paul R H J Timmers, Maarten Van den Berge, John C Whittaker, Prescott G Woodruff, Laura M Yerges-Armstrong, Olga G Troyanskaya, Olli T Raitakari, Mika Kähönen, Ozren Polašek, Ulf Gyllensten, Igor Rudan, Ian J Deary, Nicole M Probst-Hensch, Holger Schulz, Alan L James, James F Wilson, Beate Stubbe, Eleftheria Zeggini, Marjo-Riitta Jarvelin, Nick Wareham, Edwin K Silverman, Caroline Hayward, Andrew P Morris, Adam S Butterworth, Robert A Scott, Robin G Walters, Deborah A Meyers, Michael H Cho, David P Strachan, Ian P Hall, Martin D Tobin, Louise V Wain
Author Correction: New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries. Nature genetics (2024)
Aviya Litman, Natalie Sauerwald, LeeAnne Green Snyder, Jennifer H Foss-Feig, Christopher Y Park, Yun Hao, Ilan Dinstein, Chandra L Theesfeld, Olga G Troyanskaya
Decomposition of phenotypic heterogeneity in autism reveals distinct and coherent genetic programs. medRxiv : the preprint server for health sciences (2024)
Tavis J Reed, Matthew D Tyl, Alicja Tadych, Olga G Troyanskaya, Ileana M Cristea
Tapioca: a platform for predicting de novo protein-protein interactions in dynamic contexts. Nature methods 21 (3) (2024)
Tavis J Reed, Matthew D Tyl, Alicja Tadych, Olga G Troyanskaya, Ileana M Cristea
Tapioca: a platform for predicting de novo protein-protein interactions in dynamic contexts. Nature methods 21 (3) (2024)
Tavis J Reed, Matthew D Tyl, Alicja Tadych, Olga G Troyanskaya, Ileana M Cristea
Tapioca: a platform for predicting de novo protein-protein interactions in dynamic contexts. Nature methods 21 (3) (2024)
Tavis J Reed, Matthew D Tyl, Alicja Tadych, Olga G Troyanskaya, Ileana M Cristea
Tapioca: a platform for predicting de novo protein-protein interactions in dynamic contexts. Nature methods 21 (3) (2024)
Tavis J Reed, Matthew D Tyl, Alicja Tadych, Olga G Troyanskaya, Ileana M Cristea
Tapioca: a platform for predicting de novo protein-protein interactions in dynamic contexts. Nature methods (2024)
Tavis J Reed, Matthew D Tyl, Alicja Tadych, Olga G Troyanskaya, Ileana M Cristea
Tapioca: a platform for predicting de novo protein-protein interactions in dynamic contexts. Nature methods 21 (3) (2024)
Ksenia Sokolova, Kathleen M Chen, Olga G Troyanskaya
Contrastive pre-training for sequence based genomics models. bioRxiv : the preprint server for biology (2024)
R Camille Brewer, Tobias V Lanz, Caryn R Hale, Gregory D Sepich-Poore, Cameron Martino, Austin D Swafford, Thomas S Carroll, Sarah Kongpachith, Lisa K Blum, Serra E Elliott, Nathalie E Blachere, Salina Parveen, John Fak, Vicky Yao, Olga G Troyanskaya, Mayu O Frank, Michelle S Bloom, Shaghayegh Jahanbani, Alejandro M Gomez, Radhika Iyer, Nitya S Ramadoss, Orr Sharpe, Sangeetha Chandrasekaran, Lindsay B Kelmenson, Qian Wang, Heidi Wong, Holly L Torres, Mark Wiesen, Dana T Graves, Kevin D Deane, V Michael Holers, Rob Knight, Robert B Darnell, William H Robinson, Dana E Orange
Oral mucosal breaks trigger anti-citrullinated bacterial and human protein antibody responses in rheumatoid arthritis. Science translational medicine 15 (684) (2023)
Zijun Zhang, Adam R Lamson, Michael J Shelley, Olga G Troyanskaya
Interpretable neural architecture search and transfer learning for understanding CRISPR-Cas9 off-target enzymatic reactions. Nature computational science 3 (12) (2023)
Zijun Zhang, Adam R Lamson, Michael J Shelley, Olga G Troyanskaya
Interpretable neural architecture search and transfer learning for understanding CRISPR-Cas9 off-target enzymatic reactions. Nature computational science 3 (12) (2023)
R Camille Brewer, Tobias V Lanz, Caryn R Hale, Gregory D Sepich-Poore, Cameron Martino, Austin D Swafford, Thomas S Carroll, Sarah Kongpachith, Lisa K Blum, Serra E Elliott, Nathalie E Blachere, Salina Parveen, John Fak, Vicky Yao, Olga G Troyanskaya, Mayu O Frank, Michelle S Bloom, Shaghayegh Jahanbani, Alejandro M Gomez, Radhika Iyer, Nitya S Ramadoss, Orr Sharpe, Sangeetha Chandrasekaran, Lindsay B Kelmenson, Qian Wang, Heidi Wong, Holly L Torres, Mark Wiesen, Dana T Graves, Kevin D Deane, V Michael Holers, Rob Knight, Robert B Darnell, William H Robinson, Dana E Orange
Oral mucosal breaks trigger anti-citrullinated bacterial and human protein antibody responses in rheumatoid arthritis. Science translational medicine 15 (684) (2023)
Zijun Zhang, Adam R Lamson, Michael J Shelley, Olga G Troyanskaya
Interpretable neural architecture search and transfer learning for understanding CRISPR-Cas9 off-target enzymatic reactions. Nature computational science 3 (12) (2023)
Yuan Wang, William Thistlethwaite, Alicja Tadych, Frederique Ruf-Zamojski, Daniel J Bernard, Antonio Cappuccio, Elena Zaslavsky, Xi Chen, Stuart C Sealfon, Olga G Troyanskaya
Automated single-cell omics end-to-end framework with data-driven batch inference. bioRxiv : the preprint server for biology (2023)
R Camille Brewer, Tobias V Lanz, Caryn R Hale, Gregory D Sepich-Poore, Cameron Martino, Austin D Swafford, Thomas S Carroll, Sarah Kongpachith, Lisa K Blum, Serra E Elliott, Nathalie E Blachere, Salina Parveen, John Fak, Vicky Yao, Olga G Troyanskaya, Mayu O Frank, Michelle S Bloom, Shaghayegh Jahanbani, Alejandro M Gomez, Radhika Iyer, Nitya S Ramadoss, Orr Sharpe, Sangeetha Chandrasekaran, Lindsay B Kelmenson, Qian Wang, Heidi Wong, Holly L Torres, Mark Wiesen, Dana T Graves, Kevin D Deane, V Michael Holers, Rob Knight, Robert B Darnell, William H Robinson, Dana E Orange
Oral mucosal breaks trigger anti-citrullinated bacterial and human protein antibody responses in rheumatoid arthritis. Science translational medicine 15 (684) (2023)
Zijun Zhang, Adam R Lamson, Michael J Shelley, Olga G Troyanskaya
Interpretable neural architecture search and transfer learning for understanding CRISPR-Cas9 off-target enzymatic reactions. Nature computational science 3 (12) (2023)
Jens Hansen, Rachel Sealfon, Rajasree Menon, Michael T Eadon, Blue B Lake, Becky Steck, Kavya Anjani, Samir Parikh, Tara K Sigdel, Guanshi Zhang, Dušan Veličković, Daria Barwinska, Theodore Alexandrov, Dejan Dobi, Priyanka Rashmi, Edgar A Otto, Miguel Rivera, Michael P Rose, Christopher R Anderton, John P Shapiro, Annapurna Pamreddy, Seth Winfree, Yuguang Xiong, Yongqun Oliver He, Ian H de Boer, Jeffrey B Hodgin, Laura Barisoni, Abhijit S Naik, Kumar Sharma, Minnie M Sarwal, Kun Zhang, Jonathan Himmelfarb, Brad H Rovin, Tarek M El-Achkar, Zoltan G Laszik, John Cijiang He, Pierre C Dagher, M Todd Valerius, Sanjay Jain, Lisa M Satlin, Olga G Troyanskaya, Matthias Kretzler, Ravi Iyengar, Evren U Azeloglu, null null
A reference tissue atlas for the human kidney. Science advances 8 (23) (2022)
Kathleen M Chen, Aaron K Wong, Olga G Troyanskaya, Jian Zhou
A sequence-based global map of regulatory activity for deciphering human genetics. Nature genetics 54 (7) (2022)
Evan M Cofer, João Raimundo, Alicja Tadych, Yuji Yamazaki, Aaron K Wong, Chandra L Theesfeld, Michael S Levine, Olga G Troyanskaya
Modeling transcriptional regulation of model species with deep learning. Genome research 31 (6) (2021)
Aaron K Wong, Rachel S G Sealfon, Chandra L Theesfeld, Olga G Troyanskaya
Decoding disease: from genomes to networks to phenotypes. Nature reviews. Genetics 22 (12) (2021)
Jian Zhou, Olga G Troyanskaya
An analytical framework for interpretable and generalizable single-cell data analysis. Nature methods 18 (11) (2021)
Christopher Y Park, Jian Zhou, Aaron K Wong, Kathleen M Chen, Chandra L Theesfeld, Robert B Darnell, Olga G Troyanskaya
Genome-wide landscape of RNA-binding protein target site dysregulation reveals a major impact on psychiatric disorder risk. Nature genetics 53 (2) (2021)
Frederique Ruf Zamojski, Zidong Zhang, Michel Zamojski, Gregory R Smith, Natalia Mendelev, Hanqing Liu, German Nudelman, Mika Moriwaki, Hanna Pincas, Rosa Gomez Castanon, Venugopalan D Nair, Nitish Seenarine, Mary Anne S Amper, Xiang Zhou, Luisina Ongaro, Chirine Toufaily, Gauthier Schang, Joseph R Nery, Anna Bartlett, Andrew I Aldridge, Nimisha Jain, Gwen V Childs, Olga G Troyanskaya, Joseph R Ecker, Judith L Turgeon, Corrine K Welt, Daniel J Bernard, Stuart C Sealfon
Single nucleus multi-omics regulatory landscape of the murine pituitary. Nature communications 12 (1) (2021)
Joseph H Choe, Payal B Watchmaker, Milos S Simic, Ryan D Gilbert, Aileen W Li, Nira A Krasnow, Kira M Downey, Wei Yu, Diego A Carrera, Anna Celli, Juhyun Cho, Jessica D Briones, Jason M Duecker, Yitzhar E Goretsky, Ruth Dannenfelser, Lia Cardarelli, Olga G Troyanskaya, Sachdev S Sidhu, Kole T Roybal, Hideho Okada, Wendell A Lim
SynNotch-CAR T cells overcome challenges of specificity, heterogeneity, and persistence in treating glioblastoma. Science translational medicine 13 (591) (2021)
Jose Henrique Ledo, Thomas Liebmann, Ran Zhang, Jerry C Chang, Estefania P Azevedo, Eitan Wong, Hernandez Moura Silva, Olga G Troyanskaya, Victor Bustos, Paul Greengard
Presenilin 1 phosphorylation regulates amyloid-β degradation by microglia. Molecular psychiatry (2020)
Kathleen M Chen, Evan M Cofer, Jian Zhou, Olga G Troyanskaya
Selene: a PyTorch-based deep learning library for sequence data. Nature methods 16 (4) (2019)
Jian Zhou, Christopher Y Park, Chandra L Theesfeld, Aaron K Wong, Yuan Yuan, Claudia Scheckel, John J Fak, Julien Funk, Kevin Yao, Yoko Tajima, Alan Packer, Robert B Darnell, Olga G Troyanskaya
Whole-genome deep-learning analysis identifies contribution of noncoding mutations to autism risk. Nature genetics 51 (6) (2019)
Nick Shrine, Anna L Guyatt, A Mesut Erzurumluoglu, Victoria E Jackson, Brian D Hobbs, Carl A Melbourne, Chiara Batini, Katherine A Fawcett, Kijoung Song, Phuwanat Sakornsakolpat, Xingnan Li, Ruth Boxall, Nicola F Reeve, Ma'en Obeidat, Jing Hua Zhao, Matthias Wielscher, Stefan Weiss, Katherine A Kentistou, James P Cook, Benjamin B Sun, Jian Zhou, Jennie Hui, Stefan Karrasch, Medea Imboden, Sarah E Harris, Jonathan Marten, Stefan Enroth, Shona M Kerr, Ida Surakka, Veronique Vitart, Terho Lehtimäki, Richard J Allen, Per S Bakke, Terri H Beaty, Eugene R Bleecker, Yohan Bosse, Corry-Anke Brandsma, Zhengming Chen, James D Crapo, John Danesh, Dawn L DeMeo, Frank Dudbridge, Ralf Ewert, Christian Gieger, Amund Gulsvik, Anna L Hansell, Ke Hao, Joshua D Hoffman, John E Hokanson, Georg Homuth, Peter K Joshi, Philippe Joubert, Claudia Langenberg, Xuan Li, Liming Li, Kuang Lin, Lars Lind, Nicholas Locantore, Jian'an Luan, Anubha Mahajan, Joseph C Maranville, Alison D Murray, David C Nickle, Richard Packer, Margaret M Parker, Megan L Paynton, David J Porteous, Dmitry Prokopenko, Dandi Qiao, Rajesh Rawal, Heiko Runz, Ian Sayers, Don D Sin, Blair Hamilton Smith, María Soler Artigas, David Sparrow, Ruth Tal-Singer, Paul R H J Timmers, Maarten Van den Berge, John C Whittaker, Prescott G Woodruff, Laura M Yerges-Armstrong, Olga G Troyanskaya, Olli T Raitakari, Mika Kähönen, Ozren Polašek, Ulf Gyllensten, Igor Rudan, Ian J Deary, Nicole M Probst-Hensch, Holger Schulz, Alan L James, James F Wilson, Beate Stubbe, Eleftheria Zeggini, Marjo-Riitta Jarvelin, Nick Wareham, Edwin K Silverman, Caroline Hayward, Andrew P Morris, Adam S Butterworth, Robert A Scott, Robin G Walters, Deborah A Meyers, Michael H Cho, David P Strachan, Ian P Hall, Martin D Tobin, Louise V Wain, null null
New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries. Nature genetics 51 (3) (2019)
Derya Sargin, Revathy U Chottekalapanda, Kristina E Perit, Victoria Yao, Duong T Chu, Daniel W Sparks, Salina Kalik, Saige K Power, Olga G Troyanskaya, Eric F Schmidt, Paul Greengard, Evelyn K Lambe
Mapping the physiological and molecular markers of stress and SSRI antidepressant treatment in S100a10 corticostriatal neurons. Molecular psychiatry 25 (5) (2019)
Young-Suk Lee, Aaron K Wong, Alicja Tadych, Boris M Hartmann, Christopher Y Park, Veronica A DeJesus, Irene Ramos, Elena Zaslavsky, Stuart C Sealfon, Olga G Troyanskaya
Interpretation of an individual functional genomics experiment guided by massive public data. Nature methods 15 (12) (2018)
Jian Zhou, Chandra L Theesfeld, Kevin Yao, Kathleen M Chen, Aaron K Wong, Olga G Troyanskaya
Deep learning sequence-based ab initio prediction of variant effects on expression and disease risk. Nature genetics 50 (8) (2018)