Patrick J Lenehan (Patrick Lenehan)

Publication Activity (10 Years)

Years Active: 2021-2024
Publications (10 Years): 25

Top Topics

Respiratory Syndrome Coronavirus

Top Venues

The Journal of experimental medicine

medRxiv : the preprint server for health sciences

Cancer immunology research

This page only lists publications with an associated author ORCID identifier.

Publications

Paul E Oberstein, Andressa Dias Costa, Emily A Kawaler, Victoire Cardot-Ruffino, Osama E Rahma, Nina Beri, Harshabad Singh, Thomas A Abrams, Leah H Biller, James M Cleary, Peter Enzinger, Brandon M Huffman, Nadine Jackson McCleary, Kimberley J Perez, Douglas A Rubinson, Benjamin L Schlechter, Rishi Surana, Matthew B Yurgelun, S Jennifer Wang, Joshua Remland, Lauren K Brais, Naima Bollenrucher, Eugena Chang, Lestat R Ali, Patrick J Lenehan, Igor Dolgalev, Gregor Werba, Cibelle Lima, C Elizabeth Keheler, Keri M Sullivan, Michael L Dougan, Cristina Hajdu, Maya Dajee, Marc R Pelletier, Saloney Nazeer, Matthew Squires, Dafna Bar-Sagi, Brian M Wolpin, Jonathan Andrew Nowak, Diane M Simeone, Stephanie K Dougan
Blockade of IL-1β and PD-1 with combination chemotherapy reduces systemic myeloid suppression in metastatic pancreatic cancer with heterogeneous effects in the tumor. Cancer immunology research (2024)
Paul E Oberstein, Andressa Dias Costa, Emily A Kawaler, Victoire Cardot-Ruffino, Osama E Rahma, Nina Beri, Harshabad Singh, Thomas A Abrams, Leah H Biller, James M Cleary, Peter Enzinger, Brandon M Huffman, Nadine Jackson McCleary, Kimberley J Perez, Douglas A Rubinson, Benjamin L Schlechter, Rishi Surana, Matthew B Yurgelun, S Jennifer Wang, Joshua Remland, Lauren K Brais, Naima Bollenrucher, Eugena Chang, Lestat R Ali, Patrick J Lenehan, Igor Dolgalev, Gregor Werba, Cibelle Lima, C Elizabeth Keheler, Keri M Sullivan, Michael L Dougan, Cristina Hajdu, Maya Dajee, Marc R Pelletier, Saloney Nazeer, Matthew Squires, Dafna Bar-Sagi, Brian M Wolpin, Jonathan Andrew Nowak, Diane M Simeone, Stephanie K Dougan
Blockade of IL-1β and PD-1 with combination chemotherapy reduces systemic myeloid suppression in metastatic pancreatic cancer with heterogeneous effects in the tumor. Cancer immunology research (2024)
Paul E Oberstein, Andressa Dias Costa, Emily A Kawaler, Victoire Cardot-Ruffino, Osama E Rahma, Nina Beri, Harshabad Singh, Thomas A Abrams, Leah H Biller, James M Cleary, Peter Enzinger, Brandon M Huffman, Nadine Jackson McCleary, Kimberley J Perez, Douglas A Rubinson, Benjamin L Schlechter, Rishi Surana, Matthew B Yurgelun, S Jennifer Wang, Joshua Remland, Lauren K Brais, Naima Bollenrucher, Eugena Chang, Lestat R Ali, Patrick J Lenehan, Igor Dolgalev, Gregor Werba, Cibelle Lima, C Elizabeth Keheler, Keri M Sullivan, Michael L Dougan, Cristina Hajdu, Maya Dajee, Marc R Pelletier, Saloney Nazeer, Matthew Squires, Dafna Bar-Sagi, Brian M Wolpin, Jonathan Andrew Nowak, Diane M Simeone, Stephanie K Dougan
Blockade of IL1β and PD1 with Combination Chemotherapy Reduces Systemic Myeloid Suppression in Metastatic Pancreatic Cancer with Heterogeneous Effects in the Tumor. Cancer immunology research 12 (9) (2024)
Lestat R Ali, Ana Christina Garrido-Castro, Patrick J Lenehan, Naima Bollenrucher, Courtney T S Kureshi, Michael L Dougan, Shom Goel, Geoffrey I Shapiro, Sara M Tolaney, Stephanie K Dougan
PD-1 blockade and CDK4/6 inhibition augment nonoverlapping features of T cell activation in cancer. The Journal of experimental medicine 220 (4) (2023)
Lestat R Ali, Ana Christina Garrido-Castro, Patrick J Lenehan, Naima Bollenrucher, Courtney T S Kureshi, Michael L Dougan, Shom Goel, Geoffrey I Shapiro, Sara M Tolaney, Stephanie K Dougan
PD-1 blockade and CDK4/6 inhibition augment nonoverlapping features of T cell activation in cancer. The Journal of experimental medicine 220 (4) (2023)
Lestat R Ali, Ana Christina Garrido-Castro, Patrick J Lenehan, Naima Bollenrucher, Courtney T S Kureshi, Michael L Dougan, Shom Goel, Geoffrey I Shapiro, Sara M Tolaney, Stephanie K Dougan
PD-1 blockade and CDK4/6 inhibition augment nonoverlapping features of T cell activation in cancer. The Journal of experimental medicine 220 (4) (2023)
Lestat R Ali, Patrick J Lenehan, Victoire Cardot-Ruffino, Andressa Dias Costa, Matthew H G Katz, Todd W Bauer, Jonathan Andrew Nowak, Brian M Wolpin, Thomas A Abrams, Anuj K Patel, Thomas E Clancy, Jiping Wang, Joseph D Mancias, Matthew J Reilley, Chee-Chee H Stucky, Tanios S Bekaii-Saab, Rawad Elias, Nipun B Merchant, Craig L Slingluff, Osama E Rahma, Stephanie K Dougan
PD-1 blockade induces reactivation of non-productive T cell responses characterized by NF-kB signaling in patients with pancreatic cancer. Clinical cancer research : an official journal of the American Association for Cancer Research (2023)
Lestat R Ali, Ana Christina Garrido-Castro, Patrick J Lenehan, Naima Bollenrucher, Courtney T S Kureshi, Michael L Dougan, Shom Goel, Geoffrey I Shapiro, Sara M Tolaney, Stephanie K Dougan
PD-1 blockade and CDK4/6 inhibition augment nonoverlapping features of T cell activation in cancer. The Journal of experimental medicine 220 (4) (2023)
Lestat R Ali, Ana Christina Garrido-Castro, Patrick J Lenehan, Naima Bollenrucher, Courtney T S Kureshi, Michael L Dougan, Shom Goel, Geoffrey I Shapiro, Sara M Tolaney, Stephanie K Dougan
PD-1 blockade and CDK4/6 inhibition augment nonoverlapping features of T cell activation in cancer. The Journal of experimental medicine 220 (4) (2023)
Lestat R Ali, Ana Christina Garrido-Castro, Patrick J Lenehan, Naima Bollenrucher, Courtney T S Kureshi, Michael L Dougan, Shom Goel, Geoffrey I Shapiro, Sara M Tolaney, Stephanie K Dougan
PD-1 blockade and CDK4/6 inhibition augment nonoverlapping features of T cell activation in cancer. The Journal of experimental medicine 220 (4) (2023)
Arjun Puranik, Patrick J Lenehan, John C O'Horo, Colin Pawlowski, Michiel J M Niesen, Abinash Virk, Melanie D Swift, Walter Kremers, A J Venkatakrishnan, Joel E Gordon, Holly L Geyer, Leigh Lewis Speicher, Venky Soundararajan, Andrew D Badley
Durability analysis of the highly effective BNT162b2 vaccine against COVID-19. PNAS nexus 1 (3) (2022)
Michiel J M Niesen, Robert Matson, Arjun Puranik, John C O'Horo, Colin Pawlowski, Celine Vachon, Douglas W Challener, Abinash Virk, Melanie Swift, Leigh Speicher, Joel Gordon, Holly Geyer, Patrick J Lenehan, A J Venkatakrishnan, Venky Soundararajan, Andrew Badley
Third dose vaccination with mRNA-1273 or BNT162b2 vaccines improves protection against SARS-CoV-2 infection. PNAS nexus 1 (2) (2022)
Karthik Murugadoss, Michiel J M Niesen, Bharathwaj Raghunathan, Patrick J Lenehan, Pritha Ghosh, Tyler Feener, Praveen Anand, Safak Simsek, Rohit Suratekar, Travis K Hughes, Venky Soundararajan
Continuous genomic diversification of long polynucleotide fragments drives the emergence of new SARS-CoV-2 variants of concern. PNAS nexus 1 (1) (2022)
Karthik Murugadoss, Michiel J M Niesen, Bharathwaj Raghunathan, Patrick J Lenehan, Pritha Ghosh, Tyler Feener, Praveen Anand, Safak Simsek, Rohit Suratekar, Travis K Hughes, Venky Soundararajan
Continuous genomic diversification of long polynucleotide fragments drives the emergence of new SARS-CoV-2 variants of concern. PNAS nexus 1 (1) (2022)
Colin Pawlowski, Eli Silvert, John C O'Horo, Patrick J Lenehan, Douglas W Challener, Esteban Gnass, Karthik Murugadoss, Jason Ross, Leigh Speicher, Holly Geyer, A J Venkatakrishnan, Andrew D Badley, Venky Soundararajan
SARS-CoV-2 and influenza coinfection throughout the COVID-19 pandemic: an assessment of coinfection rates, cohort characteristics, and clinical outcomes. PNAS nexus 1 (3) (2022)
Pritha Ghosh, Michiel J M Niesen, Colin Pawlowski, Hari Bandi, Unice Yoo, Patrick J Lenehan, Praveen Kumar M, Mihika Nadig, Jason Ross, Sankar Ardhanari, John C O'Horo, A J Venkatakrishnan, Clifford J Rosen, Amalio Telenti, Ryan T Hurt, Venky Soundararajan
Severe acute infection and chronic pulmonary disease are risk factors for developing post-COVID-19 conditions. medRxiv : the preprint server for health sciences (2022)
Michiel J M Niesen, Robert Matson, Arjun Puranik, John C O'Horo, Colin Pawlowski, Celine Vachon, Douglas W Challener, Abinash Virk, Melanie Swift, Leigh Speicher, Joel Gordon, Holly Geyer, Patrick J Lenehan, A J Venkatakrishnan, Venky Soundararajan, Andrew Badley
Third dose vaccination with mRNA-1273 or BNT162b2 vaccines improves protection against SARS-CoV-2 infection. PNAS nexus 1 (2) (2022)
Pritha Ghosh, Michiel J M Niesen, Colin Pawlowski, Hari Bandi, Unice Yoo, Patrick J Lenehan, Praveen Kumar M, Mihika Nadig, Jason Ross, Sankar Ardhanari, John C O'Horo, A J Venkatakrishnan, Clifford J Rosen, Amalio Telenti, Ryan T Hurt, Venky Soundararajan
Severe acute infection and chronic pulmonary disease are risk factors for developing post-COVID-19 conditions. medRxiv : the preprint server for health sciences (2022)
Pritha Ghosh, Michiel J M Niesen, Colin Pawlowski, Hari Bandi, Unice Yoo, Patrick J Lenehan, Praveen Kumar M, Mihika Nadig, Jason Ross, Sankar Ardhanari, John C O'Horo, A J Venkatakrishnan, Clifford J Rosen, Amalio Telenti, Ryan T Hurt, Venky Soundararajan
Severe acute infection and chronic pulmonary disease are risk factors for developing post-COVID-19 conditions. medRxiv : the preprint server for health sciences (2022)
Michiel J M Niesen, Karthik Murugadoss, Patrick J Lenehan, Aron Marchler-Bauer, Jiyao Wang, Ryan Connor, J Rodney Brister, A J Venkatakrishnan, Venky Soundararajan
Quantifying the immunological distinctiveness of emerging SARS-CoV-2 variants in the context of prior regional herd exposure. PNAS nexus 1 (3) (2022)
A J Venkatakrishnan, Praveen Anand, Patrick J Lenehan, Rohit Suratekar, Bharathwaj Raghunathan, Michiel J M Niesen, Venky Soundararajan
On the Origins of Omicron's Unique Spike Gene Insertion. Vaccines 10 (9) (2022)
Deeksha Doddahonnaiah, Patrick J Lenehan, Travis K Hughes, David Zemmour, Enrique M Garcia-Rivera, A J Venkatakrishnan, Ramakrishna Chilaka, Apoorv Khare, Akhil Kasaraneni, Abhinav Garg, Akash Anand, Rakesh Barve, Viswanathan Thiagarajan, Venky Soundararajan
A Literature-Derived Knowledge Graph Augments the Interpretation of Single Cell RNA-seq Datasets. Genes 12 (6) (2021)
Kevin Roehle, Li Qiang, Katherine S Ventre, Daniel Heid, Lestat R Ali, Patrick J Lenehan, Max Heckler, Stephanie J Crowley, Courtney T S Kureshi, Gabrielle Ro, Anže Godicelj, M Aladdin Bhuiyan, Annan Yang, Maria Quiles Del Rey, Tamara Biary, Adrienne M Luoma, Patrick T Bruck, Jana F Tegethoff, Svenja L Nopper, Jinyang Li, Katelyn T Byrne, Marc Pelletier, Kai W Wucherpfennig, Ben Z Stanger, James J Akin, Joseph D Mancias, Judith Agudo, Michael Dougan, Stephanie K Dougan
cIAP1/2 antagonism eliminates MHC class I-negative tumors through T cell-dependent reprogramming of mononuclear phagocytes. Science translational medicine 13 (594) (2021)
Patrick J Lenehan, Assunta Cirella, Amiko M Uchida, Stephanie J Crowley, Tatyana Sharova, Genevieve Boland, Michael Dougan, Stephanie K Dougan, Max Heckler
Type 2 immunity is maintained during cancer-associated adipose tissue wasting. Immunotherapy advances 1 (1) (2021)
Ravindra Ganesh, Colin Pawlowski, John C O'Horo, Lori L Arndt, Richard Arndt, Sarah J Bell, Dennis M Bierle, Molly Destro Borgen, Sara N Hanson, Alexander Heyliger, Jennifer J Larsen, Patrick J Lenehan, Robert Orenstein, Arjun Puranik, Leigh L Speicher, Sidna M Tulledge-Scheitel, A J Venkatakrishnan, Caroline G Wilker, Andrew D Badley, Raymund R Razonable
Association of Intravenous Bamlanivimab Use with Reduced Hospitalization, Intensive Care Unit Admission, and Mortality in Patients with Mild to Moderate COVID-19. medRxiv : the preprint server for health sciences (2021)