Kai W Wucherpfennig

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 31

Top Topics

Acute Myeloid Leukemia

Histone Deacetylase

Endoscopic Submucosal Dissection

Top Venues

Cancer research

Science (New York, N.Y.)

Cancer discovery

This page only lists publications with an associated author ORCID identifier.

Publications

Francesca Alvarez Calderon, Byong Ha Kang, Oleksandr Kyrysyuk, Shiwei Zheng, Hao Wang, Nathan D Mathewson, Adrienne M Luoma, Xiaohan Ning, Jason Pyrdol, Xuan Cao, Mario L Suvà, Guo-Cheng Yuan, K Dane Wittrup, Kai W Wucherpfennig
Targeting of the CD161 inhibitory receptor enhances T-cell-mediated immunity against hematological malignancies. Blood 143 (12) (2024)
Taha Rakhshandehroo, Shreya R Mantri, Heydar Moravej, Benjamin B V Louis, Ali Salehi Farid, Leila Munaretto, Kathryn Regan, Radia M M Khan, Alexandra Wolff, Zoe Farkash, Min Cong, Adrien Kuhnast, Ali Nili, Uk-Jae Lee, Harris H Allen, Lea Berland, Ester Simkova, Safak C Uslu, Soheil Tavakolpour, Jennifer E Rowley, Elisabeth Codet, Haneyeh Shahbazian, Jessika Baral, Jason Pyrdol, Caron A Jacobson, Omar Nadeem, Hadi T Nia, Kai W Wucherpfennig, Mohammad Rashidian
A CAR enhancer increases the activity and persistence of CAR T cells. Nature biotechnology (2024)
Francesca Alvarez Calderon, Byong Ha Kang, Oleksandr Kyrysyuk, Shiwei Zheng, Hao Wang, Nathan D Mathewson, Adrienne M Luoma, Xiaohan Ning, Jason Pyrdol, Xuan Cao, Mario L Suvà, Guo-Cheng Yuan, K Dane Wittrup, Kai W Wucherpfennig
Targeting of the CD161 inhibitory receptor enhances T-cell-mediated immunity against hematological malignancies. Blood 143 (12) (2024)
Francesca Alvarez Calderon, Byong Ha Kang, Oleksandr Kyrysyuk, Shiwei Zheng, Hao Wang, Nathan D Mathewson, Adrienne M Luoma, Xiaohan Ning, Jason Pyrdol, Xuan Cao, Mario L Suvà, Guo-Cheng Yuan, K Dane Wittrup, Kai W Wucherpfennig
Targeting of the CD161 inhibitory receptor enhances T-cell-mediated immunity against hematological malignancies. Blood 143 (12) (2024)
Sabrin Tahri, Sara Piccinelli, Nang Kham Su, Luisa M Lampe, Han Dong, Juliana Vergara Cadavid, Rebecca Boiarsky, Natalie Papazian, Elizabeth D Lightbody, Amanda Cao, Jean-Baptiste Alberge, Lucas Ferrari de Andrade, Mahshid Rahmat, Yujia Shen, Laura Blanco-Fernández, Aintzane Zabaleta, Andreas Guenther, Gad Getz, Pieter Sonneveld, Tom Cupedo, Kai W Wucherpfennig, Irene M Ghobrial, Rizwan Romee
Inhibition of MICA and MICB shedding enhances memory-like NK cell-mediated cytotoxicity against multiple myeloma. Blood advances (2024)
Yoshinaga Ito, Deng Pan, Wubing Zhang, Xixi Zhang, Tiffany Y Juan, Jason W Pyrdol, Oleksandr Kyrysyuk, John G Doench, X Shirley Liu, Kai W Wucherpfennig
Addressing Tumor Heterogeneity by Sensitizing Resistant Cancer Cells to T cell-secreted Cytokines. Cancer discovery (2023)
Kimberly R Hagel, Rand Arafeh, Sydney Gang, Taylor E Arnoff, Rebecca C Larson, John G Doench, Nathan D Mathewson, Kai W Wucherpfennig, Marcela V Maus, William C Hahn
Systematic Interrogation of Tumor Cell Resistance to Chimeric Antigen Receptor T-cell Therapy in Pancreatic Cancer. Cancer research 83 (4) (2023)
Alexander L Ling, Isaac H Solomon, Ana Montalvo Landivar, Hiroshi Nakashima, Jared K Woods, Andres Santos, Nafisa Masud, Geoffrey Fell, Xiaokui M Mo, Ayse S Yilmaz, James Grant, Abigail Zhang, Joshua D Bernstock, Erickson F Torio, Hirotaka Ito, Junfeng Liu, Naoyuki Shono, Michal O Nowicki, Daniel Triggs, Patrick Halloran, Raziye Piranlioglu, Himanshu Soni, Brittany Stopa, Wenya Linda Bi, Pierpaolo Peruzzi, Ethan Chen, Seth W Malinowski, Michael C Prabhu, Yu Zeng, Anne Carlisle, Scott J Rodig, Patrick Y Wen, Eudocia Quant Lee, Lakshmi Nayak, Ugonma N Chukwueke, L Nicolas Gonzalez Castro, Sydney D Dumont, Tracy Batchelor, Kara Kittelberger, Ekaterina Tikhonova, Natalia Miheecheva, Dmitry Tabakov, Nara Shin, Alisa Gorbacheva, Artemy Shumskiy, Felix E Frenkel, Estuardo Aguilar-Cordova, Laura K Aguilar, David Krisky, James Wechuck, Andrea Manzanera, Chris Matheny, Paul P Tak, Francesca Barone, Daniel Kovarsky, Michael Mints, Mario L Suvà, Kai W Wucherpfennig, Keith L Ligon, David A Reardon, E Antonio Chiocca
Clinical trial links oncolytic immunoactivation to survival in glioblastoma. Nature (2023)
Kimberly R Hagel, Rand Arafeh, Sydney Gang, Taylor E Arnoff, Rebecca C Larson, John G Doench, Nathan D Mathewson, Kai W Wucherpfennig, Marcela V Maus, William C Hahn
Systematic Interrogation of Tumor Cell Resistance to Chimeric Antigen Receptor T-cell Therapy in Pancreatic Cancer. Cancer research 83 (4) (2023)
Yoshinaga Ito, Deng Pan, Wubing Zhang, Xixi Zhang, Tiffany Y Juan, Jason W Pyrdol, Oleksandr Kyrysyuk, John G Doench, X Shirley Liu, Kai W Wucherpfennig
Addressing Tumor Heterogeneity by Sensitizing Resistant Cancer Cells to T cell-secreted Cytokines. Cancer discovery (2023)
Francesca Alvarez Calderon, Byong Ha Kang, Oleksandr Kyrysyuk, Shiwei Zheng, Hao Wang, Nathan D Mathewson, Adrienne M Luoma, Xiaohan Ning, Jason Pyrdol, Xuan Cao, Mario L Suvà, Guo-Cheng Yuan, Karl Dane Wittrup, Kai W Wucherpfennig
Targeting of the CD161 Inhibitory Receptor Enhances T cell-mediated Immunity Against Hematological Malignancies. Blood (2023)
Kimberly R Hagel, Rand Arafeh, Sydney Gang, Taylor E Arnoff, Rebecca C Larson, John G Doench, Nathan D Mathewson, Kai W Wucherpfennig, Marcela V Maus, William C Hahn
Systematic Interrogation of Tumor Cell Resistance to Chimeric Antigen Receptor T-cell Therapy in Pancreatic Cancer. Cancer research 83 (4) (2023)
Kimberly R Hagel, Rand Arafeh, Sydney Gang, Taylor E Arnoff, Rebecca C Larson, John G Doench, Nathan D Mathewson, Kai W Wucherpfennig, Marcela V Maus, William C Hahn
Systematic Interrogation of Tumor Cell Resistance to Chimeric Antigen Receptor T-cell Therapy in Pancreatic Cancer. Cancer research 83 (4) (2023)
Giulia Notarangelo, Jessica Brooke Spinelli, Elizabeth M Perez, Gregory J Baker, Kiran Kurmi, Ilaria Elia, Sylwia A Stopka, Gerard Baquer, Jia-Ren Lin, Alexandra J Golby, Shakchhi Joshi, Heide F Baron, Jefte M Drijvers, Peter Georgiev, Alison E Ringel, Elma Zaganjor, Samuel K McBrayer, Peter Karl Sorger, Arlene H Sharpe, Kai W Wucherpfennig, Sandro Santagata, Nathalie Y R Agar, Mario L Suvà, Marcia C Haigis
Oncometabolite d-2HG alters T cell metabolism to impair CD8 + T cell function. Science (New York, N.Y.) 377 (6614) (2022)
Xintao Qiu, Nadia Boufaied, Tarek Hallal, Avery Feit, Anna de Polo, Adrienne M Luoma, Walaa Alahmadi, Janie Larocque, Giorgia Zadra, Yingtian Xie, Shengqing Gu, Qin Tang, Yi Zhang, Sudeepa Syamala, Ji-Heui Seo, Connor Bell, Edward O'Connor, Yang Liu, Edward M Schaeffer, R Jeffrey Karnes, Sheila Weinmann, Elai Davicioni, Colm Morrissey, Paloma Cejas, Leigh Ellis, Massimo Loda, Kai W Wucherpfennig, Mark M Pomerantz, Daniel E Spratt, Eva Corey, Matthew L Freedman, X Shirley Liu, Myles A Brown, Henry W Long, David P Labbé
MYC drives aggressive prostate cancer by disrupting transcriptional pause release at androgen receptor targets. Nature communications 13 (1) (2022)
Kimberly R Hagel, Rand Arafeh, Sydney Gang, Taylor E Arnoff, Rebecca C Larson, John G Doench, Nathan D Mathewson, Kai W Wucherpfennig, Marcela V Maus, William C Hahn
Systematic interrogation of tumor cell resistance to CAR T cell therapy in pancreatic cancer. Cancer research (2022)
Kimberly R Hagel, Rand Arafeh, Sydney Gang, Taylor E Arnoff, Rebecca C Larson, John G Doench, Nathan D Mathewson, Kai W Wucherpfennig, Marcela V Maus, William C Hahn
Systematic interrogation of tumor cell resistance to CAR T cell therapy in pancreatic cancer. Cancer research (2022)
Maša Alečković, Simona Cristea, Carlos R Gil Del Alcazar, Pengze Yan, Lina Ding, Ethan D Krop, Nicholas W Harper, Ernesto Rojas Jimenez, Donghao Lu, Anushree C Gulvady, Pierre Foidart, Marco Seehawer, Benedetto Diciaccio, Katherine C Murphy, Jason Pyrdol, Jayati Anand, Kodie Garza, Kai W Wucherpfennig, Rulla M Tamimi, Franziska Michor, Kornelia Polyak
Breast cancer prevention by short-term inhibition of TGFβ signaling. Nature communications 13 (1) (2022)
Soumya Badrinath, Maxence O Dellacherie, Aileen Li, Shiwei Zheng, Xixi Zhang, Miguel Sobral, Jason W Pyrdol, Kathryn L Smith, Yuheng Lu, Sabrina Haag, Hamza Ijaz, Fawn Connor-Stroud, Tsuneyasu Kaisho, Glenn Dranoff, Guo-Cheng Yuan, David J Mooney, Kai W Wucherpfennig
A vaccine targeting resistant tumours by dual T cell plus NK cell attack. Nature 606 (7916) (2022)
Kyle H Vining, Anna E Marneth, Kwasi Adu-Berchie, Joshua M Grolman, Christina M Tringides, Yutong Liu, Waihay J Wong, Olga Pozdnyakova, Mariano Severgnini, Alexander Stafford, Georg N Duda, F Stephen Hodi, Ann Mullally, Kai W Wucherpfennig, David J Mooney
Mechanical checkpoint regulates monocyte differentiation in fibrotic niches. Nature materials 21 (8) (2022)
Sascha Marx, Anze Godicelj, Kai W Wucherpfennig
A Conceptual Framework for Inducing T Cell-Mediated Immunity Against Glioblastoma. Seminars in immunopathology 44 (5) (2022)
Kevin Roehle, Li Qiang, Katherine S Ventre, Daniel Heid, Lestat R Ali, Patrick J Lenehan, Max Heckler, Stephanie J Crowley, Courtney T S Kureshi, Gabrielle Ro, Anže Godicelj, M Aladdin Bhuiyan, Annan Yang, Maria Quiles Del Rey, Tamara Biary, Adrienne M Luoma, Patrick T Bruck, Jana F Tegethoff, Svenja L Nopper, Jinyang Li, Katelyn T Byrne, Marc Pelletier, Kai W Wucherpfennig, Ben Z Stanger, James J Akin, Joseph D Mancias, Judith Agudo, Michael Dougan, Stephanie K Dougan
cIAP1/2 antagonism eliminates MHC class I-negative tumors through T cell-dependent reprogramming of mononuclear phagocytes. Science translational medicine 13 (594) (2021)
Max Heckler, Lestat R Ali, Eleanor Clancy-Thompson, Li Qiang, Katherine S Ventre, Patrick Lenehan, Kevin Roehle, Adrienne Luoma, Kelly Boelaars, Vera Peters, Julia McCreary, Tamara Boschert, Eric S Wang, Shengbao Suo, Francesco Marangoni, Thorsten R Mempel, Henry W Long, Kai W Wucherpfennig, Michael Dougan, Nathanael S Gray, Guo-Cheng Yuan, Shom Goel, Sara M Tolaney, Stephanie K Dougan
Inhibition of CDK4/6 Promotes CD8 T-cell Memory Formation. Cancer discovery 11 (10) (2021)
Sushil Kumar, Zexian Zeng, Archis Bagati, Rong En Tay, Lionel A Sanz, Stella R Hartono, Yoshinaga Ito, Fieda Abderazzaq, Elodie Hatchi, Peng Jiang, Adam N R Cartwright, Olamide Olawoyin, Nathan D Mathewson, Jason W Pyrdol, Mamie Z Li, John G Doench, Matthew A Booker, Michael Y Tolstorukov, Stephen J Elledge, Frédéric Chédin, X Shirley Liu, Kai W Wucherpfennig
CARM1 Inhibition Enables Immunotherapy of Resistant Tumors by Dual Action on Tumor Cells and T Cells. Cancer discovery 11 (8) (2021)
Peng Jiang, Yu Zhang, Beibei Ru, Yuan Yang, Trang Vu, Rohit Paul, Amer Mirza, Grégoire Altan-Bonnet, Lingrui Liu, Eytan Ruppin, Lalage Wakefield, Kai W Wucherpfennig
Systematic investigation of cytokine signaling activity at the tissue and single-cell levels. Nature methods 18 (10) (2021)
Pedro Henrique Alves da Silva, Samantha Xing, Andriana G Kotini, Eirini P Papapetrou, Xiaoyu Song, Kai W Wucherpfennig, John O Mascarenhas, Lucas Ferrari de Andrade
MICA/B antibody induces macrophage-mediated immunity against acute myeloid leukemia. Blood (2021)
Joep Grootjans, Niklas Krupka, Shuhei Hosomi, Juan D Matute, Thomas Hanley, Svetlana Saveljeva, Thomas Gensollen, Jarom Heijmans, Hai Li, Julien P Limenitakis, Stephanie Christine Ganal-Vonarburg, Shengbao Suo, Adrienne M Luoma, Yosuke Shimodaira, Jinzhi Duan, David Q Shih, Margaret E Conner, Jonathan N Glickman, Gwenny M Fuhler, Noah W Palm, Marcel R de Zoete, Christien J van der Woude, Guo-Cheng Yuan, Kai W Wucherpfennig, Stephan R Targan, Philip Rosenstiel, Richard A Flavell, Kathy D McCoy, Andrew J Macpherson, Arthur Kaser, Richard S Blumberg
Epithelial endoplasmic reticulum stress orchestrates a protective IgA response. Science (New York, N.Y.) 363 (6430) (2019)
Mariella G Filbin, Michael Mints, Volker Hovestadt, McKenzie L Shaw, Leah E Escalante, Nathan D Mathewson, Cyril Neftel, Nelli Frank, Kristine Pelton, Christine M Hebert, Christine Haberler, Keren Yizhak, Johannes Gojo, Kristof Egervari, Christopher Mount, Peter van Galen, Dennis M Bonal, Quang-De Nguyen, Alexander Beck, Claire Sinai, Thomas Czech, Christian Dorfer, Liliana Goumnerova, Cinzia Lavarino, Angel Montero Carcaboso, Jaume Mora, Ravindra Mylvaganam, Christina C Luo, Andreas Peyrl, Mara Popović, Amedeo A Azizi, Tracy T Batchelor, Matthew P Frosch, Maria Martinez-Lage, Mark W Kieran, Pratiti Bandopadhayay, Rameen Beroukhim, Gerhard Fritsch, Gad A Getz, Orit Rozenblatt-Rosen, Kai W Wucherpfennig, David N Louis, Michelle Monje, Irene Slavc, Keith L Ligon, Todd R Golub, Aviv Regev, Bradley E Bernstein, Mario L Suvà
Developmental and oncogenic programs in H3K27M gliomas dissected by single-cell RNA-seq. Science (New York, N.Y.) 360 (6386) (2018)
Lucas Ferrari de Andrade, Rong En Tay, Deng Pan, Adrienne M Luoma, Yoshinaga Ito, Soumya Badrinath, Daphne Tsoucas, Bettina Franz, Kenneth F May, Christopher J Harvey, Sebastian Kobold, Jason W Pyrdol, Charles Yoon, Guo-Cheng Yuan, Frank Stephen Hodi, Glenn Dranoff, Kai W Wucherpfennig
Antibody-mediated inhibition of MICA and MICB shedding promotes NK cell-driven tumor immunity. Science (New York, N.Y.) 359 (6383) (2018)
Deng Pan, Aya Kobayashi, Peng Jiang, Lucas Ferrari de Andrade, Rong En Tay, Adrienne M Luoma, Daphne Tsoucas, Xintao Qiu, Klothilda Lim, Prakash Rao, Henry W Long, Guo-Cheng Yuan, John G Doench, Myles Brown, X Shirley Liu, Kai W Wucherpfennig
A major chromatin regulator determines resistance of tumor cells to T cell-mediated killing. Science (New York, N.Y.) 359 (6377) (2018)
Yoshinaga Ito, Orr Ashenberg, Jason Pyrdol, Adrienne M Luoma, Orit Rozenblatt-Rosen, Matan Hofree, Elena Christian, Lucas Ferrari de Andrade, Rong En Tay, Luc Teyton, Aviv Regev, Stephanie K Dougan, Kai W Wucherpfennig
Rapid CLIP dissociation from MHC II promotes an unusual antigen presentation pathway in autoimmunity. The Journal of experimental medicine 215 (10) (2018)