Stephanie K Dougan

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 35

Top Topics

Squamous Cell Carcinoma

Liver Metastases

Neoadjuvant Chemotherapy

Top Venues

Journal for immunotherapy of cancer

Journal of immunology (Baltimore, Md. : 1950)

Cancer immunology research

This page only lists publications with an associated author ORCID identifier.

Publications

Julien Dilly, Megan T Hoffman, Laleh Abbassi, Ziyue Li, Francesca Paradiso, Brendan D Parent, Connor J Hennessey, Alexander C Jordan, Micaela Morgado, Shatavisha Dasgupta, Giselle A Uribe, Annan Yang, Kevin S Kapner, Felix P Hambitzer, Li Qiang, Hanrong Feng, Jacob Geisberg, Junning Wang, Kyle E Evans, Hengyu Lu, Aislyn Schalck, Ningping Feng, Anastasia M Lopez, Christopher A Bristow, Michael P Kim, Kimal I Rajapakshe, Vahid Bahrambeigi, Jennifer A Roth, Kavita Garg, Paola A Guerrero, Ben Z Stanger, Simona Cristea, Scott W Lowe, Timour Baslan, Eliezer Van Allen, Joseph D Mancias, Emily Chan, Abraham Anderson, Yuliya V Katlinskaya, Alex K Shalek, David S Hong, Shubham Pant, Jill Hallin, Kenna Anderes, Peter Olson, Timothy P Heffernan, Seema Chugh, James G Christensen, Anirban Maitra, Brian M Wolpin, Srivatsan Raghavan, Jonathan Andrew Nowak, Peter S Winter, Stephanie K Dougan, Andrew J Aguirre
Mechanisms of resistance to oncogenic KRAS inhibition in pancreatic cancer. Cancer discovery (2024)
Paul E Oberstein, Andressa Dias Costa, Emily A Kawaler, Victoire Cardot-Ruffino, Osama E Rahma, Nina Beri, Harshabad Singh, Thomas A Abrams, Leah H Biller, James M Cleary, Peter Enzinger, Brandon M Huffman, Nadine Jackson McCleary, Kimberley J Perez, Douglas A Rubinson, Benjamin L Schlechter, Rishi Surana, Matthew B Yurgelun, S Jennifer Wang, Joshua Remland, Lauren K Brais, Naima Bollenrucher, Eugena Chang, Lestat R Ali, Patrick J Lenehan, Igor Dolgalev, Gregor Werba, Cibelle Lima, C Elizabeth Keheler, Keri M Sullivan, Michael L Dougan, Cristina Hajdu, Maya Dajee, Marc R Pelletier, Saloney Nazeer, Matthew Squires, Dafna Bar-Sagi, Brian M Wolpin, Jonathan Andrew Nowak, Diane M Simeone, Stephanie K Dougan
Blockade of IL-1β and PD-1 with combination chemotherapy reduces systemic myeloid suppression in metastatic pancreatic cancer with heterogeneous effects in the tumor. Cancer immunology research (2024)
Paul E Oberstein, Andressa Dias Costa, Emily A Kawaler, Victoire Cardot-Ruffino, Osama E Rahma, Nina Beri, Harshabad Singh, Thomas A Abrams, Leah H Biller, James M Cleary, Peter Enzinger, Brandon M Huffman, Nadine Jackson McCleary, Kimberley J Perez, Douglas A Rubinson, Benjamin L Schlechter, Rishi Surana, Matthew B Yurgelun, S Jennifer Wang, Joshua Remland, Lauren K Brais, Naima Bollenrucher, Eugena Chang, Lestat R Ali, Patrick J Lenehan, Igor Dolgalev, Gregor Werba, Cibelle Lima, C Elizabeth Keheler, Keri M Sullivan, Michael L Dougan, Cristina Hajdu, Maya Dajee, Marc R Pelletier, Saloney Nazeer, Matthew Squires, Dafna Bar-Sagi, Brian M Wolpin, Jonathan Andrew Nowak, Diane M Simeone, Stephanie K Dougan
Blockade of IL-1β and PD-1 with combination chemotherapy reduces systemic myeloid suppression in metastatic pancreatic cancer with heterogeneous effects in the tumor. Cancer immunology research (2024)
Brandon M Huffman, Harshabad Singh, Lestat R Ali, Nora Horick, S Jennifer Wang, Megan T Hoffman, Katherine A Metayer, Shayla Murray, Alexandra Bird, Thomas A Abrams, Leah H Biller, Jennifer A Chan, Jeffrey A Meyerhardt, Nadine J McCleary, Wolfram Goessling, Anuj K Patel, Jeffrey S Wisch, Matthew B Yurgelun, Kent Mouw, Brendan Reardon, Eliezer Van Allen, Jessica A Zerillo, Jeffrey W Clark, Aparna Parikh, Robert J Mayer, Benjamin Schlechter, Kimmie Ng, Sunil Kumar, Catherine Del Vecchio Fitz, Charlotte Kuperwasser, Glenn J Hanna, Andrew L Coveler, Douglas A Rubinson, Emma L Welsh, Kathleen Pfaff, Scott Rodig, Stephanie K Dougan, James M Cleary
Biomarkers of pembrolizumab efficacy in advanced anal squamous cell carcinoma: analysis of a phase II clinical trial and a cohort of long-term responders. Journal for immunotherapy of cancer 12 (1) (2024)
Brandon M Huffman, Harshabad Singh, Lestat R Ali, Nora Horick, S Jennifer Wang, Megan T Hoffman, Katherine A Metayer, Shayla Murray, Alexandra Bird, Thomas A Abrams, Leah H Biller, Jennifer A Chan, Jeffrey A Meyerhardt, Nadine J McCleary, Wolfram Goessling, Anuj K Patel, Jeffrey S Wisch, Matthew B Yurgelun, Kent Mouw, Brendan Reardon, Eliezer Van Allen, Jessica A Zerillo, Jeffrey W Clark, Aparna Parikh, Robert J Mayer, Benjamin Schlechter, Kimmie Ng, Sunil Kumar, Catherine Del Vecchio Fitz, Charlotte Kuperwasser, Glenn J Hanna, Andrew L Coveler, Douglas A Rubinson, Emma L Welsh, Kathleen Pfaff, Scott Rodig, Stephanie K Dougan, James M Cleary
Biomarkers of pembrolizumab efficacy in advanced anal squamous cell carcinoma: analysis of a phase II clinical trial and a cohort of long-term responders. Journal for immunotherapy of cancer 12 (1) (2024)
Paul E Oberstein, Andressa Dias Costa, Emily A Kawaler, Victoire Cardot-Ruffino, Osama E Rahma, Nina Beri, Harshabad Singh, Thomas A Abrams, Leah H Biller, James M Cleary, Peter Enzinger, Brandon M Huffman, Nadine Jackson McCleary, Kimberley J Perez, Douglas A Rubinson, Benjamin L Schlechter, Rishi Surana, Matthew B Yurgelun, S Jennifer Wang, Joshua Remland, Lauren K Brais, Naima Bollenrucher, Eugena Chang, Lestat R Ali, Patrick J Lenehan, Igor Dolgalev, Gregor Werba, Cibelle Lima, C Elizabeth Keheler, Keri M Sullivan, Michael L Dougan, Cristina Hajdu, Maya Dajee, Marc R Pelletier, Saloney Nazeer, Matthew Squires, Dafna Bar-Sagi, Brian M Wolpin, Jonathan Andrew Nowak, Diane M Simeone, Stephanie K Dougan
Blockade of IL1β and PD1 with Combination Chemotherapy Reduces Systemic Myeloid Suppression in Metastatic Pancreatic Cancer with Heterogeneous Effects in the Tumor. Cancer immunology research 12 (9) (2024)
Brandon M Huffman, Harshabad Singh, Lestat R Ali, Nora Horick, S Jennifer Wang, Megan T Hoffman, Katherine A Metayer, Shayla Murray, Alexandra Bird, Thomas A Abrams, Leah H Biller, Jennifer A Chan, Jeffrey A Meyerhardt, Nadine J McCleary, Wolfram Goessling, Anuj K Patel, Jeffrey S Wisch, Matthew B Yurgelun, Kent Mouw, Brendan Reardon, Eliezer Van Allen, Jessica A Zerillo, Jeffrey W Clark, Aparna Parikh, Robert J Mayer, Benjamin Schlechter, Kimmie Ng, Sunil Kumar, Catherine Del Vecchio Fitz, Charlotte Kuperwasser, Glenn J Hanna, Andrew L Coveler, Douglas A Rubinson, Emma L Welsh, Kathleen Pfaff, Scott Rodig, Stephanie K Dougan, James M Cleary
Biomarkers of pembrolizumab efficacy in advanced anal squamous cell carcinoma: analysis of a phase II clinical trial and a cohort of long-term responders. Journal for immunotherapy of cancer 12 (1) (2024)
Brandon M Huffman, Harshabad Singh, Lestat R Ali, Nora Horick, S Jennifer Wang, Megan T Hoffman, Katherine A Metayer, Shayla Murray, Alexandra Bird, Thomas A Abrams, Leah H Biller, Jennifer A Chan, Jeffrey A Meyerhardt, Nadine J McCleary, Wolfram Goessling, Anuj K Patel, Jeffrey S Wisch, Matthew B Yurgelun, Kent Mouw, Brendan Reardon, Eliezer Van Allen, Jessica A Zerillo, Jeffrey W Clark, Aparna Parikh, Robert J Mayer, Benjamin Schlechter, Kimmie Ng, Sunil Kumar, Catherine Del Vecchio Fitz, Charlotte Kuperwasser, Glenn J Hanna, Andrew L Coveler, Douglas A Rubinson, Emma L Welsh, Kathleen Pfaff, Scott Rodig, Stephanie K Dougan, James M Cleary
Biomarkers of pembrolizumab efficacy in advanced anal squamous cell carcinoma: analysis of a phase II clinical trial and a cohort of long-term responders. Journal for immunotherapy of cancer 12 (1) (2024)
Harshabad Singh, Joanne Xiu, Kevin S Kapner, Chen Yuan, Raja R Narayan, Matthew J Oberley, Alex P Farrell, Rishi Surana, Brandon M Huffman, Kimberley J Perez, James M Cleary, Alexander C Jordan, Andressa Dias Costa, Hannah L Williams, Srivatsan Raghavan, Benjamin A Weinberg, Michael J Pishvaian, Rachna T Shroff, Sanjay Goel, Stephanie K Dougan, Jonathan Andrew Nowak, David B Spetzler, George W Sledge, Brian M Wolpin, Andrew J Aguirre
Clinical and genomic features of classical and basal transcriptional subtypes in pancreatic cancer. Clinical cancer research : an official journal of the American Association for Cancer Research (2024)
Brandon M Huffman, Harshabad Singh, Lestat R Ali, Nora Horick, S Jennifer Wang, Megan T Hoffman, Katherine A Metayer, Shayla Murray, Alexandra Bird, Thomas A Abrams, Leah H Biller, Jennifer A Chan, Jeffrey A Meyerhardt, Nadine J McCleary, Wolfram Goessling, Anuj K Patel, Jeffrey S Wisch, Matthew B Yurgelun, Kent Mouw, Brendan Reardon, Eliezer Van Allen, Jessica A Zerillo, Jeffrey W Clark, Aparna Parikh, Robert J Mayer, Benjamin Schlechter, Kimmie Ng, Sunil Kumar, Catherine Del Vecchio Fitz, Charlotte Kuperwasser, Glenn J Hanna, Andrew L Coveler, Douglas A Rubinson, Emma L Welsh, Kathleen Pfaff, Scott Rodig, Stephanie K Dougan, James M Cleary
Biomarkers of pembrolizumab efficacy in advanced anal squamous cell carcinoma: analysis of a phase II clinical trial and a cohort of long-term responders. Journal for immunotherapy of cancer 12 (1) (2024)
Katherine S Ventre, Kevin Roehle, Elisa Bello, Aladdin M Bhuiyan, Tamara Biary, Stephanie J Crowley, Patrick T Bruck, Max Heckler, Patrick J Lenehan, Lestat R Ali, Courtney T S Kureshi, Victoria Lippert, Eleanor Clancy-Thompson, Winiffer D Conce Alberto, Megan T Hoffman, Li Qiang, Marc Pelletier, James J Akin, Michael Dougan, Stephanie K Dougan
cIAP1/2 Antagonism Induces Antigen-Specific T Cell-Dependent Immunity. Journal of immunology (Baltimore, Md. : 1950) 210 (7) (2023)
Min-Sik Lee, Courtney Dennis, Insia Naqvi, Lucas Dailey, Alireza Lorzadeh, George Ye, Tamara Zaytouni, Ashley Adler, Daniel S Hitchcock, Lin Lin, Megan T Hoffman, Aladdin M Bhuiyan, Jaimie L Barth, Miranda E Machacek, Mari A Mino-Kenudson, Stephanie K Dougan, Unmesh Jadhav, Andrew T Chan, Nada Y Kalaany
Ornithine aminotransferase supports polyamine synthesis in pancreatic cancer. Nature (2023)
Katherine S Ventre, Kevin Roehle, Elisa Bello, Aladdin M Bhuiyan, Tamara Biary, Stephanie J Crowley, Patrick T Bruck, Max Heckler, Patrick J Lenehan, Lestat R Ali, Courtney T S Kureshi, Victoria Lippert, Eleanor Clancy-Thompson, Winiffer D Conce Alberto, Megan T Hoffman, Li Qiang, Marc Pelletier, James J Akin, Michael Dougan, Stephanie K Dougan
cIAP1/2 Antagonism Induces Antigen-Specific T Cell-Dependent Immunity. Journal of immunology (Baltimore, Md. : 1950) (2023)
Michael J Walsh, Lestat R Ali, Patrick Lenehan, Courtney T Kureshi, Rakeeb Kureshi, Michael Dougan, David M Knipe, Stephanie K Dougan
Blockade of innate inflammatory cytokines TNF α , IL-1 β , or IL-6 overcomes virotherapy-induced cancer equilibrium to promote tumor regression. Immunotherapy advances 3 (1) (2023)
Rakeeb Kureshi, Elisa Bello, Courtney T S Kureshi, Michael J Walsh, Victoria Lippert, Megan T Hoffman, Michael Dougan, Tyler Longmire, Michael Wichroski, Stephanie K Dougan
DGKα/ζ inhibition lowers the TCR affinity threshold and potentiates antitumor immunity. Science advances 9 (47) (2023)
Lestat R Ali, Patrick J Lenehan, Victoire Cardot-Ruffino, Andressa Dias Costa, Matthew H G Katz, Todd W Bauer, Jonathan Andrew Nowak, Brian M Wolpin, Thomas A Abrams, Anuj K Patel, Thomas E Clancy, Jiping Wang, Joseph D Mancias, Matthew J Reilley, Chee-Chee H Stucky, Tanios S Bekaii-Saab, Rawad Elias, Nipun B Merchant, Craig L Slingluff, Osama E Rahma, Stephanie K Dougan
PD-1 blockade induces reactivation of non-productive T cell responses characterized by NF-kB signaling in patients with pancreatic cancer. Clinical cancer research : an official journal of the American Association for Cancer Research (2023)
Katherine S Ventre, Kevin Roehle, Elisa Bello, Aladdin M Bhuiyan, Tamara Biary, Stephanie J Crowley, Patrick T Bruck, Max Heckler, Patrick J Lenehan, Lestat R Ali, Courtney T S Kureshi, Victoria Lippert, Eleanor Clancy-Thompson, Winiffer D Conce Alberto, Megan T Hoffman, Li Qiang, Marc Pelletier, James J Akin, Michael Dougan, Stephanie K Dougan
cIAP1/2 Antagonism Induces Antigen-Specific T Cell-Dependent Immunity. Journal of immunology (Baltimore, Md. : 1950) 210 (7) (2023)
Megan T Hoffman, Stephanie K Dougan
Pancreatic Neoplasms Are Frighteningly Common: A Role for Immune Surveillance? Cancer discovery 13 (6) (2023)
Matthew H G Katz, Gina R Petroni, Todd Bauer, Matthew J Reilley, Brian M Wolpin, Chee-Chee Stucky, Tanios S Bekaii-Saab, Rawad Elias, Nipun Merchant, Andressa Dias Costa, Patrick Lenehan, Victoire Cardot-Ruffino, Scott Rodig, Kathleen Pfaff, Stephanie K Dougan, Jonathan Andrew Nowak, Gauri R Varadhachary, Craig L Slingluff, Osama Rahma
Multicenter randomized controlled trial of neoadjuvant chemoradiotherapy alone or in combination with pembrolizumab in patients with resectable or borderline resectable pancreatic adenocarcinoma. Journal for immunotherapy of cancer 11 (12) (2023)
Victoire Cardot-Ruffino, Naima Bollenrucher, Luisa Delius, S Jennifer Wang, Lauren K Brais, Joshua Remland, C Elizabeth Keheler, Keri M Sullivan, Thomas A Abrams, Leah H Biller, Peter C Enzinger, Nadine J McCleary, Anuj K Patel, Douglas A Rubinson, Benjamin Schlechter, Sarah Slater, Matthew B Yurgelun, James M Cleary, Kimberly Perez, Michael Dougan, Kimmie Ng, Brian M Wolpin, Harshabad Singh, Stephanie K Dougan
G-CSF rescue of FOLFIRINOX-induced neutropenia leads to systemic immune suppression in mice and humans. Journal for immunotherapy of cancer 11 (6) (2023)
Min-Sik Lee, Courtney Dennis, Insia Naqvi, Lucas Dailey, Alireza Lorzadeh, George Ye, Tamara Zaytouni, Ashley Adler, Daniel S Hitchcock, Lin Lin, Megan T Hoffman, Aladdin M Bhuiyan, Jaimie L Barth, Miranda E Machacek, Mari A Mino-Kenudson, Stephanie K Dougan, Unmesh Jadhav, Andrew T Chan, Nada Y Kalaany
Ornithine aminotransferase supports polyamine synthesis in pancreatic cancer. Nature (2023)
Andressa Dias Costa, Sara A Väyrynen, Akhil Chawla, Jinming Zhang, Juha P Väyrynen, Mai Chan Lau, Hannah L Williams, Chen Yuan, Vicente Morales-Oyarvide, Dalia Elganainy, Harshabad Singh, James M Cleary, Kimberley J Perez, Kimmie Ng, William A Freed-Pastor, Joseph D Mancias, Stephanie K Dougan, Jiping Wang, Douglas A Rubinson, Richard F Dunne, Margaret M Kozak, Lauren K Brais, Emma R Hill, Thomas E Clancy, David C Linehan, Daniel T Chang, Aram F Hezel, Albert C Koong, Andrew J Aguirre, Brian M Wolpin, Jonathan Andrew Nowak
Neoadjuvant Chemotherapy Is Associated with Altered Immune Cell Infiltration and an Anti-Tumorigenic Microenvironment in Resected Pancreatic Cancer. Clinical cancer research : an official journal of the American Association for Cancer Research 28 (23) (2022)
Li Qiang, Stephanie K Dougan
Bicarbonate transport as a vulnerability in pancreatic cancer. Nature cancer 3 (12) (2022)
Li Qiang, Stephanie K Dougan
Bicarbonate transport as a vulnerability in pancreatic cancer. Nature cancer 3 (12) (2022)
Li Qiang, Stephanie K Dougan
Bicarbonate transport as a vulnerability in pancreatic cancer. Nature cancer 3 (12) (2022)
Abdel Nasser Hosein, Stephanie K Dougan, Andrew J Aguirre, Anirban Maitra
Translational advances in pancreatic ductal adenocarcinoma therapy. Nature cancer 3 (3) (2022)
Li Qiang, Stephanie K Dougan
Bicarbonate transport as a vulnerability in pancreatic cancer. Nature cancer (2022)
Alfredo Quijano-Rubio, Aladdin M Bhuiyan, Huilin Yang, Isabel Leung, Elisa Bello, Lestat R Ali, Kevin Zhangxu, Jilliane Bruffey, Jung-Ho Chun, Wentao Wang, Marc J Lajoie, Rashmi Ravichandran, Yun-Huai Kuo, Stephanie K Dougan, Stanley R Riddell, Jamie B Spangler, Michael Dougan, Daniel Adriano Silva, Julien S Baker
A split, conditionally active mimetic of IL-2 reduces the toxicity of systemic cytokine therapy. Nature biotechnology (2022)
Connor S Dobson, Anna N Reich, Stephanie Gaglione, Blake E Smith, Ellen J Kim, Jiayi Dong, Larance Ronsard, Vintus Okonkwo, Daniel Lingwood, Michael Dougan, Stephanie K Dougan, Michael E Birnbaum
Antigen identification and high-throughput interaction mapping by reprogramming viral entry. Nature methods 19 (4) (2022)
Kevin Roehle, Li Qiang, Katherine S Ventre, Daniel Heid, Lestat R Ali, Patrick J Lenehan, Max Heckler, Stephanie J Crowley, Courtney T S Kureshi, Gabrielle Ro, Anže Godicelj, M Aladdin Bhuiyan, Annan Yang, Maria Quiles Del Rey, Tamara Biary, Adrienne M Luoma, Patrick T Bruck, Jana F Tegethoff, Svenja L Nopper, Jinyang Li, Katelyn T Byrne, Marc Pelletier, Kai W Wucherpfennig, Ben Z Stanger, James J Akin, Joseph D Mancias, Judith Agudo, Michael Dougan, Stephanie K Dougan
cIAP1/2 antagonism eliminates MHC class I-negative tumors through T cell-dependent reprogramming of mononuclear phagocytes. Science translational medicine 13 (594) (2021)
Courtney T Stump, Kevin Roehle, Nataly Manjarrez Orduno, Stephanie K Dougan
Radiation combines with immune checkpoint blockade to enhance T cell priming in a murine model of poorly immunogenic pancreatic cancer. Open biology 11 (11) (2021)
Eleanor Clancy-Thompson, Gui Zhen Chen, Nelson M LaMarche, Lestat R Ali, Hee-Jin Jeong, Stephanie J Crowley, Kelly Boelaars, Michael B Brenner, Lydia Lynch, Stephanie K Dougan
Transnuclear mice reveal Peyer's patch iNKT cells that regulate B-cell class switching to IgG1. The EMBO journal 38 (14) (2019)
Stephanie K Dougan, Michael Dougan
SMAC mimetics throw a molecular switch to control TH17 responses. Science signaling 12 (596) (2019)
Michael Dougan, Stephanie K Dougan
Targeting Immunotherapy to the Tumor Microenvironment. Journal of cellular biochemistry 118 (10) (2017)
Hee-Jin Jeong, Gita C Abhiraman, Craig M Story, Jessica R Ingram, Stephanie K Dougan
Generation of Ca2+-independent sortase A mutants with enhanced activity for protein and cell surface labeling. PloS one 12 (12) (2017)