Pavel A Petukhov

ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 9

Top Venues

ChemMedChem

ACS infectious diseases

PLoS pathogens

ACS chemical biology

University of Illinois at Chicago

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University of Illinois at Chicago Oct 01 2003

United States

Professor :: Pharmaceutical Sciences

Publications

Matteo Ardini, Sammy Y Aboagye, Valentina Z Petukhova, Irida Kastrati, Rodolfo Ippoliti, Gregory R J Thatcher, Pavel A Petukhov, David L Williams, Francesco Angelucci
The "Doorstop Pocket" In Thioredoxin Reductases─An Unexpected Druggable Regulator of the Catalytic Machinery. Journal of medicinal chemistry (2024)
Valentina Z Petukhova, Samuel Yaw Aboagye, Matteo Ardini, Rachel P Lullo, Francesca Fata, Margaret E Byrne, Federica Gabriele, Lucy M Martin, Luke N M Harding, Vamshikrishna Gone, Bikash Dangi, Daniel D Lantvit, Dejan Nikolic, Rodolfo Ippoliti, Gregory Effantin, Wai Li Ling, Jeremy J Johnson, Gregory R J Thatcher, Francesco Angelucci, David L Williams, Pavel A Petukhov
Non-covalent inhibitors of thioredoxin glutathione reductase with schistosomicidal activity in vivo. Nature communications 14 (1) (2023)
Francesca Fata, Ilaria Silvestri, Matteo Ardini, Rodolfo Ippoliti, Luana Di Leandro, Nicola Demitri, Maurizio Polentarutti, Adele Di Matteo, Haining Lyu, Gregory R J Thatcher, Pavel A Petukhov, David L Williams, Francesco Angelucci
Probing the Surface of a Parasite Drug Target Thioredoxin Glutathione Reductase Using Small Molecule Fragments. ACS infectious diseases 7 (7) (2021)
Taha Y Taha, Varada Anirudhan, Umaporn Limothai, Daniel D Loeb, Pavel A Petukhov, Alan McLachlan
Modulation of hepatitis B virus pregenomic RNA stability and splicing by histone deacetylase 5 enhances viral biosynthesis. PLoS pathogens 16 (8) (2020)
Haining Lyu, Pavel A Petukhov, Paul R Banta, Ajit Jadhav, Wendy A Lea, Qing Cheng, Elias S J Arnér, Anton Simeonov, Gregory R J Thatcher, Francesco Angelucci, David L Williams
Characterization of Lead Compounds Targeting the Selenoprotein Thioredoxin Glutathione Reductase for Treatment of Schistosomiasis. ACS infectious diseases 6 (3) (2020)
Shaimaa M Aboukhatwa, Thomas W Hanigan, Taha Y Taha, Jayaprakash Neerasa, Rajeev Ranjan, Eman E El-Bastawissy, Mohamed A Elkersh, Tarek F El-Moselhy, Jonna Frasor, Nadim Mahmud, Alan McLachlan, Pavel A Petukhov
Structurally Diverse Histone Deacetylase Photoreactive Probes: Design, Synthesis, and Photolabeling Studies in Live Cells and Tissue. ChemMedChem 14 (11) (2019)
Ilaria Silvestri, Haining Lyu, Francesca Fata, Giovanna Boumis, Adriana E Miele, Matteo Ardini, Rodolfo Ippoliti, Andrea Bellelli, Ajit Jadhav, Wendy A Lea, Anton Simeonov, Qing Cheng, Elias S J Arnér, Gregory R J Thatcher, Pavel A Petukhov, David L Williams, Francesco Angelucci
Fragment-Based Discovery of a Regulatory Site in Thioredoxin Glutathione Reductase Acting as "Doorstop" for NADPH Entry. ACS chemical biology 13 (8) (2018)
Hazem Abdelkarim, Raghupathi Neelarapu, Antonett Madriaga, Aditya S Vaidya, Irida Kastrati, Bhargava Karumudi, Yue-Ting Wang, Taha Y Taha, Gregory R J Thatcher, Jonna Frasor, Pavel A Petukhov
Design, Synthesis, Molecular Modeling, and Biological Evaluation of Novel Amine-based Histone Deacetylase Inhibitors. ChemMedChem 12 (24) (2017)
Thomas W Hanigan, Taha Y Taha, Shaimaa M Aboukhatwa, Jonna Frasor, Pavel A Petukhov
Scaffold dependent histone deacetylase (HDAC) inhibitor induced re-equilibration of the subcellular localization and post-translational modification state of class I HDACs. PloS one 12 (10) (2017)

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Publication Activity (10 Years)

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Pavel A Petukhov