Peppi Karppinen (Peppi Koivunen)

Publication Activity (10 Years)

Years Active: 2019-2024
Publications (10 Years): 21

Top Topics

Intellectual Disability

Top Venues

Cancer research

Pflugers Archiv : European journal of physiology

Cellular and molecular life sciences : CMLS

This page only lists publications with an associated author ORCID identifier.

Publications

Selina Mäkinen, Sreesha Sree, Tuulia Ala-Nisula, Henric Kultalahti, Peppi Karppinen, Heikki A Koistinen
Activation of the hypoxia-inducible factor pathway by roxadustat improves glucose metabolism in human primary myotubes from men. Diabetologia (2024)
Brooke A Brown, Paul J Myers, Sara J Adair, Jason R Pitarresi, Shiv K Sah-Teli, Logan A Campbell, William S Hart, Michelle C Barbeau, Kelsey Leong, Nicholas Seyler, William J Kane, Kyoung Eun Lee, Edward B Stelow, Marieke K Jones, M Celeste Simon, Peppi Karppinen, Todd W Bauer, Ben Z Stanger, Matthew J Lazzara
A histone methylation-MAPK signaling axis drives durable epithelial-mesenchymal transition in hypoxic pancreatic cancer. Cancer research (2024)
Tuulia Ala-Nisula, Riikka Halmetoja, Henri Leinonen, Margareta Kurkela, Henna-Riikka Lipponen, Samuli Sakko, Mikko Karpale, Antti M Salo, Niina Sissala, Tapio Röning, Ghulam Shere Raza, Kari Antero Mäkelä, Jérôme Thevenot, Karl-Heinz Herzig, Raisa Serpi, Johanna Myllyharju, Heikki Tanila, Peppi Karppinen, Elitsa Y Dimova
Metabolic characteristics of transmembrane prolyl 4-hydroxylase (P4H-TM) deficient mice. Pflugers Archiv : European journal of physiology 476 (9) (2024)
Brooke A Brown, Paul J Myers, Sara J Adair, Jason R Pitarresi, Shiv K Sah-Teli, Logan A Campbell, William S Hart, Michelle C Barbeau, Kelsey Leong, Nicholas Seyler, William J Kane, Kyoung Eun Lee, Edward B Stelow, Marieke K Jones, M Celeste Simon, Peppi Karppinen, Todd W Bauer, Ben Z Stanger, Matthew J Lazzara
A Histone Methylation-MAPK Signaling Axis Drives Durable Epithelial-Mesenchymal Transition in Hypoxic Pancreatic Cancer. Cancer research 84 (11) (2024)
Tuulia Ala-Nisula, Riikka Halmetoja, Henri Leinonen, Margareta Kurkela, Henna-Riikka Lipponen, Samuli Sakko, Mikko Karpale, Antti M Salo, Niina Sissala, Tapio Röning, Ghulam Shere Raza, Kari Antero Mäkelä, Jérôme Thevenot, Karl-Heinz Herzig, Raisa Serpi, Johanna Myllyharju, Heikki Tanila, Peppi Karppinen, Elitsa Y Dimova
Metabolic characteristics of transmembrane prolyl 4-hydroxylase (P4H-TM) deficient mice. Pflugers Archiv : European journal of physiology (2024)
Tuulia Ala-Nisula, Riikka Halmetoja, Henri Leinonen, Margareta Kurkela, Henna-Riikka Lipponen, Samuli Sakko, Mikko Karpale, Antti M Salo, Niina Sissala, Tapio Röning, Ghulam Shere Raza, Kari Antero Mäkelä, Jérôme Thevenot, Karl-Heinz Herzig, Raisa Serpi, Johanna Myllyharju, Heikki Tanila, Peppi Karppinen, Elitsa Y Dimova
Metabolic characteristics of transmembrane prolyl 4-hydroxylase (P4H-TM) deficient mice. Pflugers Archiv : European journal of physiology 476 (9) (2024)
Brooke A Brown, Paul J Myers, Sara J Adair, Jason R Pitarresi, Shiv K Sah-Teli, Logan A Campbell, William S Hart, Michelle C Barbeau, Kelsey Leong, Nicholas Seyler, William J Kane, Kyoung Eun Lee, Edward B Stelow, Marieke K Jones, M Celeste Simon, Peppi Karppinen, Todd W Bauer, Ben Z Stanger, Matthew J Lazzara
A histone methylation-MAPK signaling axis drives durable epithelial-mesenchymal transition in hypoxic pancreatic cancer. Cancer research (2024)
Tuulia Ala-Nisula, Riikka Halmetoja, Henri Leinonen, Margareta Kurkela, Henna-Riikka Lipponen, Samuli Sakko, Mikko Karpale, Antti M Salo, Niina Sissala, Tapio Röning, Ghulam Shere Raza, Kari Antero Mäkelä, Jérôme Thevenot, Karl-Heinz Herzig, Raisa Serpi, Johanna Myllyharju, Heikki Tanila, Peppi Karppinen, Elitsa Y Dimova
Metabolic characteristics of transmembrane prolyl 4-hydroxylase (P4H-TM) deficient mice. Pflugers Archiv : European journal of physiology 476 (9) (2024)
Brooke A Brown, Paul J Myers, Sara J Adair, Jason R Pitarresi, Shiv K Sah-Teli, Logan A Campbell, William S Hart, Michelle C Barbeau, Kelsey Leong, Nicholas Seyler, William J Kane, Kyoung Eun Lee, Edward B Stelow, Marieke K Jones, M Celeste Simon, Peppi Karppinen, Todd W Bauer, Ben Z Stanger, Matthew J Lazzara
A histone methylation-MAPK signaling axis drives durable epithelial-mesenchymal transition in hypoxic pancreatic cancer. Cancer research (2024)
Brennan J Wadsworth, Marina Leiwe, Eleanor A Minogue, Pedro P Cunha, Viktor Engman, Carolin Brombach, Christos Asvestis, Shiv K Sah-Teli, Emilia Marklund, Peppi Karppinen, Jorge L Ruas, Helene Rundqivst, Johanna T Lanner, Randall S Johnson
A 2-hydroxybutyrate-mediated feedback loop regulates muscular fatigue. eLife 12 (2024)
Brooke A Brown, Paul J Myers, Sara J Adair, Jason R Pitarresi, Shiv K Sah-Teli, Logan A Campbell, William S Hart, Michelle C Barbeau, Kelsey Leong, Nicholas Seyler, William J Kane, Kyoung Eun Lee, Edward B Stelow, Marieke K Jones, M Celeste Simon, Peppi Karppinen, Todd W Bauer, Ben Z Stanger, Matthew J Lazzara
A Histone Methylation-MAPK Signaling Axis Drives Durable Epithelial-Mesenchymal Transition in Hypoxic Pancreatic Cancer. Cancer research 84 (11) (2024)
Kathryn Gunn, Matti Myllykoski, John Z Cao, Manna Ahmed, Bofu Huang, Betty Rouaisnel, Bill H Diplas, Michael M Levitt, Ryan E Looper, John G Doench, Keith L Ligon, Harley I Kornblum, Samuel K McBrayer, Hai Yan, Cihangir Duy, Lucy A Godley, Peppi Karppinen, Julie-Aurore Losman
(R)-2-hydroxyglutarate inhibits KDM5 histone lysine demethylases to drive transformation in IDH-mutant cancers. Cancer discovery (2023)
Tuulia Ala-Nisula, Shiv K Sah-Teli, Veli-Pekka Ronkainen, Elitsa Y Dimova, Peppi Karppinen
Human phytanoyl-CoA dioxygenase domain-containing 1 (PHYHD1) is a putative oxygen sensor associated with RNA and carbohydrate metabolism. FEBS letters (2023)
Minna Kraatari, Leila Soikkonen, Matti Myllykoski, Yalda Jamshidi, Ehsan G Karimiani, Jonna Komulainen-Ebrahim, Hanna Kallankari, Cyril Mignot, Christel Depienne, Boris Keren, Marie-Christine Nougues, Zahra Alsahlawi, Antonio Romito, Javier Martini, Mehran B Toosi, Christopher J Carroll, Kornelia Tripolszki, Peter Bauer, Johanna Uusimaa, Aida Maria Bertoli-Avella, Peppi Karppinen, Elisa J Rahikkala
HIDEA syndrome is caused by biallelic, pathogenic, rare or founder P4HTM variants impacting the active site or the overall stability of the P4H-TM protein. Clinical genetics 102 (5) (2022)
Teemu Ollonen, Margareta Kurkela, Anna Laitakari, Samuli Sakko, Henna Koivisto, Johanna Myllyharju, Heikki Tanila, Raisa Serpi, Peppi Karppinen
Activation of the hypoxia response protects mice from amyloid-β accumulation. Cellular and molecular life sciences : CMLS 79 (8) (2022)
Niina Sissala, Elisa Myllymäki, Florian Mohr, Riikka Halmetoja, Paula Kuvaja, Elitsa Y Dimova, Peppi Karppinen
Hypoxia ameliorates maternal diet-induced insulin resistance during pregnancy while having a detrimental effect on the placenta. Physiological reports 10 (9) (2022)
Nadiya Byts, Subodh Sharma, Jenny Laurila, Prodeep Paudel, Ilkka Miinalainen, Veli-Pekka Ronkainen, Reetta Hinttala, Kid Törnquist, Peppi Karppinen, Johanna Myllyharju
Transmembrane Prolyl 4-Hydroxylase is a Novel Regulator of Calcium Signaling in Astrocytes. eNeuro 8 (1) (2021)
Juha Auvinen, Joona Tapio, Ville Karhunen, Johannes Kettunen, Raisa Serpi, Elitsa Y Dimova, Dipender Gill, Pasi Soininen, Tuija Heini Tammelin, Juha Mykkänen, Katri Puukka, Mika Kähönen, Emma Raitoharju, Terho Lehtimäki, Mika Ala-Korpela, Olli T Raitakari, Sirkka Keinänen-Kiukaanniemi, Marjo-Riitta Jarvelin, Peppi Karppinen
Systematic evaluation of the association between hemoglobin levels and metabolic profile implicates beneficial effects of hypoxia. Science advances 7 (29) (2021)
Anna Laitakari, Joona Tapio, Kari A Mäkelä, Karl-Heinz Herzig, Franziska Dengler, Helena Gylling, Gail Walkinshaw, Johanna Myllyharju, Elitsa Y Dimova, Raisa Serpi, Peppi Karppinen
HIF-P4H-2 inhibition enhances intestinal fructose metabolism and induces thermogenesis protecting against NAFLD. Journal of molecular medicine (Berlin, Germany) 98 (5) (2020)
Nina Kozlova, Daniela Mennerich, Anatoliy Samoylenko, Elitsa Y Dimova, Peppi Karppinen, Ekaterina Biterova, Kati Richter, Antti Hassinen, Sakari Kellokumpu, Aki Manninen, Ilkka Miinalainen, Virpi Glumoff, Lloyd Ruddock, Lyudmyla Borysivna Drobot, Thomas Kietzmann
The Pro-Oncogenic Adaptor CIN85 Acts as an Inhibitory Binding Partner of Hypoxia-Inducible Factor Prolyl Hydroxylase 2. Cancer research 79 (16) (2019)
Abhishek A Chakraborty, Tuomas Laukka, Matti Myllykoski, Alison E Ringel, Matthew A Booker, Michael Yevgeniy Tolstorukov, Yuzhong Jeff Meng, Samuel R Meier, Rebecca B Jennings, Amanda L Creech, Zachary T Herbert, Samuel K McBrayer, Benjamin A Olenchock, Jacob D Jaffe, Marcia C Haigis, Rameen Beroukhim, Sabina Signoretti, Peppi Karppinen, William G Kaelin
Histone demethylase KDM6A directly senses oxygen to control chromatin and cell fate. Science (New York, N.Y.) 363 (6432) (2019)