Sabina Signoretti

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 21

Top Topics

Renal Cell Carcinoma

Small Cell Lung Cancer

Regulatory T Cells

Top Venues

Clinical cancer research : an official journal of the American Association for Cancer Research

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Science (New York, N.Y.)

Cancer immunology research

This page only lists publications with an associated author ORCID identifier.

Publications

Xiyue Wang, Junhan Zhao, Eliana Marostica, Wei Yuan, Jietian Jin, Jiayu Zhang, Ruijiang Li, Hongping Tang, Kanran Wang, Yu Li, Fang Wang, Yulong Peng, Junyou Zhu, Jing Zhang, Christopher R Jackson, Jun Zhang, Deborah Dillon, Nancy U Lin, Lynette Sholl, Thomas Denize, David Meredith, Keith L Ligon, Sabina Signoretti, Shuji Ogino, Jeffrey A Golden, Mac Lean P Nasrallah, Xiao Han, Sen Yang, Kun-Hsing Yu
A pathology foundation model for cancer diagnosis and prognosis prediction. Nature (2024)
Leslie Duplaquet, Yixiang Li, Matthew A Booker, Yingtian Xie, Sarah Naomi Olsen, Radhika A Patel, Deli Hong, Charles Hatton, Thomas Denize, Emily Walton, Yasmin N Laimon, Rong Li, Yijia Jiang, Roderick T Bronson, Jackson Southard, Shuqiang Li, Sabina Signoretti, Xintao Qiu, Paloma Cejas, Scott A Armstrong, Henry W Long, Michael Y Tolstorukov, Michael C Haffner, Matthew G Oser
KDM6A epigenetically regulates subtype plasticity in small cell lung cancer. Nature cell biology (2023)
Thomas Denize, Opeyemi A Jagede, Sayed Matar, Nourhan El Ahmar, Destiny J West, Emily Walton, Aseman Sheshdeh Bagheri, Varunika Savla, Yasmin Nabil Laimon, Saurabh Gupta, Sai Vikram Vemula, David A Braun, Kelly P Burke, Paul J Catalano, Gordon J Freeman, Robert J Motzer, Michael B Atkins, David F McDermott, Arlene H Sharpe, Toni K Choueiri, Sabina Signoretti
PD-1 Expression on Intratumoral Regulatory T Cells is Associated with Lack of Benefit from Anti-PD-1 Therapy in Metastatic Clear Cell Renal Cell Carcinoma Patients. Clinical cancer research : an official journal of the American Association for Cancer Research (2023)
Renee Maria Saliby, Amin H Nassar, Ziad Bakouny, Valisha Shah, Wanling Xie, Ronan Flippot, Thomas Denize, M Harry Kane, Katrine N Madsen, Miriam Ficial, Laure Hirsch, Xiao X Wei, John A Steinarter, Lauren C Harshman, Ulka N Vaishampayan, Mariano Severgnini, David F McDermott, Gwo-Shu Mary Lee, Wenxin Xu, Eliezer Van Allen, Bradley Alexander McGregor, Sabina Signoretti, Toni K Choueiri, Rana R McKay, David A Braun
Circulating and intratumoral immune determinants of response to atezolizumab plus bevacizumab in patients with variant histology or sarcomatoid renal cell carcinoma. Cancer immunology research (2023)
Thomas Denize, Yue Hou, Jean-Christophe Pignon, Emily Walton, Destiny J West, Gordon J Freeman, David A Braun, Catherine J Wu, Saurabh Gupta, Robert J Motzer, Michael B Atkins, David McDermott, Toni K Choueiri, Sachet A Shukla, Sabina Signoretti
Transcriptomic Correlates of Tumor Cell PD-L1 Expression and Response to Nivolumab Monotherapy in Metastatic Clear Cell Renal Cell Carcinoma. Clinical cancer research : an official journal of the American Association for Cancer Research 28 (18) (2022)
Xueliang Gao, Yubao Wang, Caroline Fidalgo Ribeiro, Cherubin Manokaran, Hyeyoun Chang, Thanh Von, Silvia Rodrigues, Onur Cizmecioglu, Shidong Jia, Manav Korpal, Joshua M Korn, Zhigang Wang, Fabienne Schmit, Lan Jiang, Raymond Pagliarini, Yi Yang, Isha Sethi, Sabina Signoretti, Guo-Cheng Yuan, Massimo Loda, Jean J Zhao, Thomas M Roberts
Blocking PI3K p110β Attenuates Development of PTEN-Deficient Castration-Resistant Prostate Cancer. Molecular cancer research : MCR 20 (5) (2022)
Bradley Alexander McGregor, Wanling Xie, Elio Adib, Walter M Stadler, Yousef Zakharia, Aijai Alva, M Dror Michaelson, Shilpa Gupta, Elaine T Lam, Subrina Farah, Amin H Nassar, Xiao X Wei, Kerry L Kilbridge, Lauren C Harshman, Sabina Signoretti, Lynette M Sholl, David J Kwiatkowski, Rana R McKay, Toni K Choueiri
Biomarker-Based Phase II Study of Sapanisertib (TAK-228): An mTORC1/2 Inhibitor in Patients With Refractory Metastatic Renal Cell Carcinoma. JCO precision oncology 6 (2022)
Thomas Denize, Subrina Farah, Alessia Cimadamore, Abdallah Flaifel, Emily Walton, Maura A Sticco-Ivins, Chris Labaki, David A Braun, Maxine Sun, Evelyn Wang, Wanling Xie, Toni K Choueiri, Sabina Signoretti
Biomarkers of Angiogenesis and Clinical Outcomes to Cabozantinib and Everolimus in Patients with Metastatic Renal Cell Carcinoma from the Phase III METEOR Trial. Clinical cancer research : an official journal of the American Association for Cancer Research 28 (4) (2022)
Michael B Atkins, Opeyemi A Jagede, Naomi B Haas, David F McDermott, Mehmet A Bilen, Mark N Stein, Jeffrey A Sosman, Robert Alter, Elizabeth R Plimack, Moshe C Ornstein, Michael E Hurwitz, David J Peace, Sabina Signoretti, Thomas Denize, Alessia Cimadamore, Catherine J Wu, David A Braun, David J Einstein, Paul J Catalano, Hans Hammers
Phase II Study of Nivolumab and Salvage Nivolumab/Ipilimumab in Treatment-Naive Patients With Advanced Clear Cell Renal Cell Carcinoma (HCRN GU16-260-Cohort A). Journal of clinical oncology : official journal of the American Society of Clinical Oncology 40 (25) (2022)
Matthew L Bootsma, Rana R McKay, Hamid Emamekhoo, Rory M Bade, Jennifer L Schehr, Matthew C Mannino, Anupama Singh, Serena K Wolfe, Zachery D Schultz, Jamie M Sperger, Wanling Xie, Sabina Signoretti, Christos E Kyriakopoulos, David Kosoff, Edwin J Abel, Kyle T Helzer, Nicholas Rydzewski, Hamza Bakhtiar, Yue Shi, Grace Blitzer, Michael Bassetti, John M Floberg, Menggang Yu, Nan Sethakorn, Marina N Sharifi, Paul M Harari, Toni K Choueiri, Joshua M Lang, Shuang G Zhao
Longitudinal Molecular Profiling of Circulating Tumor Cells in Metastatic Renal Cell Carcinoma. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 40 (31) (2022)
Toni K Choueiri, Laurence Albiges, Michael B Atkins, Ziad Bakouny, Gennady Bratslavsky, David A Braun, Naomi B Haas, John B A G Haanen, A Ari Hakimi, Michael A S Jewett, Eric Jonasch, William G Kaelin, Payal Kapur, Chris Labaki, Bryan Lewis, David F McDermott, Sumanta K Pal, Kevin Pels, Susan Poteat, Thomas Powles, W Kimryn Rathmell, Brian I Rini, Sabina Signoretti, Nizar M Tannir, Robert G Uzzo, Hans J Hammers
From Basic Science to Clinical Translation in Kidney Cancer: A Report from the Second Kidney Cancer Research Summit. Clinical cancer research : an official journal of the American Association for Cancer Research 28 (5) (2022)
Eliana Marostica, Rebecca Barber, Thomas Denize, Isaac S Kohane, Sabina Signoretti, Jeffrey A Golden, Kun-Hsing Yu
Development of a Histopathology Informatics Pipeline for Classification and Prediction of Clinical Outcomes in Subtypes of Renal Cell Carcinoma. Clinical cancer research : an official journal of the American Association for Cancer Research 27 (10) (2021)
Prateek Khanna, Hong Jie Soh, Chun-Hau Chen, Ruchi Saxena, Seema Amin, Maura Naughton, Patrick Neset Joslin, Andrew Moore, Ziad Bakouny, Carol O'Callaghan, Paul J Catalano, Sabina Signoretti, Rana McKay, Toni K Choueiri, Manoj Bhasin, Thomas Walther, Rupal S Bhatt
ACE2 abrogates tumor resistance to VEGFR inhibitors suggesting angiotensin-(1-7) as a therapy for clear cell renal cell carcinoma. Science translational medicine 13 (577) (2021)
Carla Calagua, Miriam Ficial, Caroline S Jansen, Taghreed Hirz, Luke Del Balzo, Scott Wilkinson, Ross Lake, Anson T Ku, Olga Voznesensky, David B Sykes, Philip J Saylor, Huihui Ye, Sabina Signoretti, Haydn Kissick, Adam G Sowalsky, Steven P Balk, David J Einstein
A Subset of Localized Prostate Cancer Displays an Immunogenic Phenotype Associated with Losses of Key Tumor Suppressor Genes. Clinical cancer research : an official journal of the American Association for Cancer Research 27 (17) (2021)
Deli Hong, Erik H Knelson, Yixiang Li, Yavuz T Durmaz, Wenhua Gao, Emily Walton, Amir Vajdi, Tran Thai, Maura Sticco-Ivins, Amin H Sabet, Kristen L Jones, Anna C Schinzel, Roderick T Bronson, Quang-De Nguyen, Michael Y Tolstorukov, Marina Vivero, Sabina Signoretti, David A Barbie, Matthew G Oser
Plasticity in the Absence of NOTCH Uncovers a RUNX2-Dependent Pathway in Small Cell Lung Cancer. Cancer research (2021)
Nizar M Tannir, Sabina Signoretti, Toni K Choueiri, David F McDermott, Robert J Motzer, Abdallah Flaifel, Jean-Christophe Pignon, Miriam Ficial, Osvaldo Arén Frontera, Saby George, Thomas Powles, Frede Donskov, Michael R Harrison, Philippe Barthélémy, Scott S Tykodi, Judit Kocsis, Alain Ravaud, Jeronimo R Rodriguez-Cid, Sumanta K Pal, Andre M Murad, Yuko Ishii, Shruti Shally Saggi, M Brent McHenry, Brian I Rini
Efficacy and Safety of Nivolumab Plus Ipilimumab versus Sunitinib in First-line Treatment of Patients with Advanced Sarcomatoid Renal Cell Carcinoma. Clinical cancer research : an official journal of the American Association for Cancer Research 27 (1) (2020)
Miriam Ficial, Opeyemi A Jagede, Miriam Sant'Angelo, Yue Hou, Abdallah Flaifel, Jean-Christophe Pignon, David A Braun, Megan Wind-Rotolo, Maura A Sticco-Ivins, Paul J Catalano, Gordon J Freeman, Arlene H Sharpe, F Stephen Hodi, Robert J Motzer, Catherine J Wu, Michael B Atkins, David F McDermott, Sachet A Shukla, Toni K Choueiri, Sabina Signoretti
Expression of T-Cell Exhaustion Molecules and Human Endogenous Retroviruses as Predictive Biomarkers for Response to Nivolumab in Metastatic Clear Cell Renal Cell Carcinoma. Clinical cancer research : an official journal of the American Association for Cancer Research 27 (5) (2020)
Rupal S Bhatt, Abdulla Berjis, Julie C Konge, Kathleen M Mahoney, Alyssa N Klee, Samuel S Freeman, Chun-Hau Chen, Opeyemi A Jagede, Paul J Catalano, Jean-Christophe Pignon, Maura Sticco-Ivins, Baogong Zhu, Ping Hua, Jo Soden, Jie Zhu, David F McDermott, Antonio R Arulanandam, Sabina Signoretti, Gordon J Freeman
KIR3DL3 Is an Inhibitory Receptor for HHLA2 that Mediates an Alternative Immunoinhibitory Pathway to PD1. Cancer immunology research 9 (2) (2020)
Hilary E Nicholson, Zeshan Tariq, Benjamin E Housden, Rebecca B Jennings, Laura A Stransky, Norbert Perrimon, Sabina Signoretti, William G Kaelin
HIF-independent synthetic lethality between CDK4/6 inhibition and VHL loss across species. Science signaling 12 (601) (2019)
Abhishek A Chakraborty, Tuomas Laukka, Matti Myllykoski, Alison E Ringel, Matthew A Booker, Michael Yevgeniy Tolstorukov, Yuzhong Jeff Meng, Samuel R Meier, Rebecca B Jennings, Amanda L Creech, Zachary T Herbert, Samuel K McBrayer, Benjamin A Olenchock, Jacob D Jaffe, Marcia C Haigis, Rameen Beroukhim, Sabina Signoretti, Peppi Karppinen, William G Kaelin
Histone demethylase KDM6A directly senses oxygen to control chromatin and cell fate. Science (New York, N.Y.) 363 (6432) (2019)
Diana Miao, Claire A Margolis, Wenhua Gao, Martin H Voss, Wei Li, Dylan J Martini, Craig Norton, Dominick Bosse, Stephanie M Wankowicz, Dana Cullen, Christine Horak, Megan Wind-Rotolo, Adam Tracy, Marios Giannakis, Frank Stephen Hodi, Charles G Drake, Mark W. Ball, Mohamad E Allaf, Alexandra Snyder, Matthew D Hellmann, Thai H Ho, Robert J Motzer, Sabina Signoretti, William G Kaelin, Toni K Choueiri, Eliezer Van Allen
Genomic correlates of response to immune checkpoint therapies in clear cell renal cell carcinoma. Science (New York, N.Y.) 359 (6377) (2018)