William G Kaelin

ORCID

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 12

Top Venues

Science (New York, N.Y.)

Circulation

Science signaling

Nature reviews. Cancer

Dana-Farber Cancer Institute

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Dana-Farber Cancer Institute

United States

Sidney Farber Professor of Medicine :: Medical Oncology

Howard Hughes Medical Institute

United States

Principal Investigator

Publications

Gregory A Wyant, Qinqin Jiang, Madhu Singh, Shariq Qayyum, Clara Levrero, Bradley A Maron, William G Kaelin
Induction of DEPP1 by HIF Mediates Multiple Hallmarks of Ischemic Cardiomyopathy. Circulation (2024)
Gregory A Wyant, Qinqin Jiang, Madhu Singh, Shariq Qayyum, Clara Levrero, Bradley A Maron, William G Kaelin
Induction of DEPP1 by HIF Mediates Multiple Hallmarks of Ischemic Cardiomyopathy. Circulation (2024)
Gregory A Wyant, Qinqin Jiang, Madhu Singh, Shariq Qayyum, Clara Levrero, Bradley A Maron, William G Kaelin
Induction of DEPP1 by HIF Mediates Multiple Hallmarks of Ischemic Cardiomyopathy. Circulation (2024)
Tao Zhang, Daichao Xu, Jianping Liu, Min Wang, Li-Juan Duan, Min Liu, Huyan Meng, Yuan Zhuang, Huibing Wang, Yingnan Wang, Mingming Lv, Zhengyi Zhang, Jia Hu, Linyu Shi, Rui Guo, Xingxing Xie, Hui Liu, Emily Erickson, Yaru Wang, Wenyu Yu, Fabin Dang, Dongxian Guan, Cong Jiang, Xiaoming Dai, Hiroyuki Inuzuka, Peiqiang Yan, Jingchao Wang, Mrigya Babuta, Gewei Lian, Zhenbo Tu, Ji Miao, Gyongyi Szabo, Guo-Hua Fong, Antoine E Karnoub, Yu-Ru Lee, Lifeng Pan, William G Kaelin, Junying Yuan, Wenyi Wei
Prolonged hypoxia alleviates prolyl hydroxylation-mediated suppression of RIPK1 to promote necroptosis and inflammation. Nature cell biology (2023)
Gregory A Wyant, Wenyu Yu, IIias P Doulamis, Rio S Nomoto, Mossab Y Saeed, Thomas Duignan, James D McCully, William G Kaelin
Mitochondrial remodeling and ischemic protection by G protein-coupled receptor 35 agonists. Science (New York, N.Y.) 377 (6606) (2022)
Vidyasagar Koduri, Leslie Duplaquet, Benjamin L Lampson, Adam C Wang, Amin H Sabet, Mette Ishoey, Joshiawa Paulk, Mingxing Teng, Isaac S Harris, Jennifer E Endress, Xiaoxi Liu, Ethan Dasilva, Joao A Paulo, Kimberly J Briggs, John G Doench, Christopher J Ott, Tinghu Zhang, Katherine Aleisha Donovan, Eric S Fischer, Steven P Gygi, Nathanael S Gray, James E Bradner, Jeffrey A Medin, Sara J Buhrlage, Matthew G Oser, William G Kaelin
Targeting oncoproteins with a positive selection assay for protein degraders. Science advances 7 (6) (2021)
Julie-Aurore Losman, Peppi Koivunen, William G Kaelin
2-Oxoglutarate-dependent dioxygenases in cancer. Nature reviews. Cancer 20 (12) (2020)
Hilary E Nicholson, Zeshan Tariq, Benjamin E Housden, Rebecca B Jennings, Laura A Stransky, Norbert Perrimon, Sabina Signoretti, William G Kaelin
HIF-independent synthetic lethality between CDK4/6 inhibition and VHL loss across species. Science signaling 12 (601) (2019)
Abhishek A Chakraborty, Tuomas Laukka, Matti Myllykoski, Alison E Ringel, Matthew A Booker, Michael Yevgeniy Tolstorukov, Yuzhong Jeff Meng, Samuel R Meier, Rebecca B Jennings, Amanda L Creech, Zachary T Herbert, Samuel K McBrayer, Benjamin A Olenchock, Jacob D Jaffe, Marcia C Haigis, Rameen Beroukhim, Sabina Signoretti, Peppi Karppinen, William G Kaelin
Histone demethylase KDM6A directly senses oxygen to control chromatin and cell fate. Science (New York, N.Y.) 363 (6432) (2019)
Diana Miao, Claire A Margolis, Wenhua Gao, Martin H Voss, Wei Li, Dylan J Martini, Craig Norton, Dominick Bosse, Stephanie M Wankowicz, Dana Cullen, Christine Horak, Megan Wind-Rotolo, Adam Tracy, Marios Giannakis, Frank Stephen Hodi, Charles G Drake, Mark W. Ball, Mohamad E Allaf, Alexandra Snyder, Matthew D Hellmann, Thai H Ho, Robert J Motzer, Sabina Signoretti, William G Kaelin, Toni K Choueiri, Eliezer Van Allen
Genomic correlates of response to immune checkpoint therapies in clear cell renal cell carcinoma. Science (New York, N.Y.) 359 (6377) (2018)
Jing Zhang, Tao Wu, Jeremy M Simon, Mamoru Takada, Ryoichi Saito, Cheng Fan, Xian-De Liu, Eric Jonasch, Ling Xie, Xian Chen, Xiaosai Yao, Bin Tean Teh, Patrick Tan, Xingnan Zheng, Mingjie Li, Cortney Lawrence, Jie Fan, Geng-Xi Jiang, Xijuan Liu, Lianxin Hu, Jun Wang, Chengheng Liao, Kai Hong, Giada Zurlo, Joel S Parker, James T Auman, Charles M Perou, W Kimryn Rathmell, William Y Kim, Marc W Kirschner, William G Kaelin, Albert S Baldwin, Yang Zhang
VHL substrate transcription factor ZHX2 as an oncogenic driver in clear cell renal cell carcinoma. Science (New York, N.Y.) 361 (6399) (2018)
Abhishek A Chakraborty, Eijiro Nakamura, Jun Qi, Amanda L Creech, Jacob D Jaffe, Joshiawa Paulk, Jesse S Novak, Kshithija Nagulapalli, Samuel K McBrayer, Glenn S Cowley, Javier Pineda, Jiaxi Song, Yaoyu E Wang, Steven A Carr, David E Root, Sabina Signoretti, James E Bradner, William G Kaelin
HIF activation causes synthetic lethality between the VHL tumor suppressor and the EZH1 histone methyltransferase. Science translational medicine 9 (398) (2018)

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Publication Activity (10 Years)

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William G Kaelin