Peter J Tonge (Peter Tonge)

Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 46

Top Venues

Journal of medicinal chemistry

ACS chemical biology

ACS infectious diseases

Biochemistry

Stony Brook University

University of Birmingham (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Stony Brook University

United States

Professor :: Chemistry

Education History

University of Birmingham Sep 01 1982 - Feb 28 1986

United Kingdom

PHD :: Biochemistry

University of Birmingham Sep 01 1979 - Jun 01 1982

United Kingdom

BSC :: Biochemistry

Publications

YongLe He, Jinnette Tolentino Collado, James N Iuliano, Helena A Woroniecka, Christopher R Hall, Agnieszka A Gil, Sergey P Laptenok, Gregory M Greetham, Boris Illarionov, Adelbert Bacher, Markus Fischer, Jarrod B French, Andras Lukacs, Stephen R Meech, Peter J Tonge
Elucidating the Signal Transduction Mechanism of the Blue-Light-Regulated Photoreceptor YtvA: From Photoactivation to Downstream Regulation. ACS chemical biology 19 (3) (2024)
Kaixuan Li, Alexa L Gilberti, Jocelyn A Marden, Hari K Akula, Alyssa C Pollard, Shuwen Guo, Bao Hu, Peter J Tonge, Wenchao Qu
Synthesis and Biological Evaluation of Fluorine-18 and Deuterium Labeled l-Fluoroalanines as Positron Emission Tomography Imaging Agents for Cancer Detection. Journal of medicinal chemistry (2024)
Kaixuan Li, Alexa L Gilberti, Jocelyn A Marden, Hari K Akula, Alyssa C Pollard, Shuwen Guo, Bao Hu, Peter J Tonge, Wenchao Qu
Synthesis and Biological Evaluation of Fluorine-18 and Deuterium Labeled l-Fluoroalanines as Positron Emission Tomography Imaging Agents for Cancer Detection. Journal of medicinal chemistry 67 (12) (2024)
Kaixuan Li, Jinnette Tolentino Collado, Jocelyn A Marden, Alyssa C Pollard, Shuwen Guo, Peter J Tonge, Wenchao Qu
Biological Evaluation of d-[ 18 F]Fluoroalanine and d-[ 18 F]Fluoroalanine- d 3 as Positron Emission Tomography Imaging Tracers for Bacterial Infection. Journal of medicinal chemistry 67 (16) (2024)
Kaixuan Li, Jinnette Tolentino Collado, Jocelyn A Marden, Alyssa C Pollard, Shuwen Guo, Peter J Tonge, Wenchao Qu
Biological Evaluation of d-[ 18 F]Fluoroalanine and d-[ 18 F]Fluoroalanine- d 3 as Positron Emission Tomography Imaging Tracers for Bacterial Infection. Journal of medicinal chemistry 67 (16) (2024)
YongLe He, Jinnette Tolentino Collado, James N Iuliano, Helena A Woroniecka, Christopher R Hall, Agnieszka A Gil, Sergey P Laptenok, Gregory M Greetham, Boris Illarionov, Adelbert Bacher, Markus Fischer, Jarrod B French, Andras Lukacs, Stephen R Meech, Peter J Tonge
Elucidating the Signal Transduction Mechanism of the Blue-Light-Regulated Photoreceptor YtvA: From Photoactivation to Downstream Regulation. ACS chemical biology 19 (3) (2024)
Kaixuan Li, Alexa L Gilberti, Jocelyn A Marden, Hari K Akula, Alyssa C Pollard, Shuwen Guo, Bao Hu, Peter J Tonge, Wenchao Qu
Synthesis and Biological Evaluation of Fluorine-18 and Deuterium Labeled l-Fluoroalanines as Positron Emission Tomography Imaging Agents for Cancer Detection. Journal of medicinal chemistry 67 (12) (2024)
YongLe He, Jinnette Tolentino Collado, James N Iuliano, Helena A Woroniecka, Christopher R Hall, Agnieszka A Gil, Sergey P Laptenok, Gregory M Greetham, Boris Illarionov, Adelbert Bacher, Markus Fischer, Jarrod B French, Andras Lukacs, Stephen R Meech, Peter J Tonge
Elucidating the Signal Transduction Mechanism of the Blue-Light-Regulated Photoreceptor YtvA: From Photoactivation to Downstream Regulation. ACS chemical biology 19 (3) (2024)
YongLe He, Jinnette Tolentino Collado, James N Iuliano, Helena A Woroniecka, Christopher R Hall, Agnieszka A Gil, Sergey P Laptenok, Gregory M Greetham, Boris Illarionov, Adelbert Bacher, Markus Fischer, Jarrod B French, Andras Lukacs, Stephen R Meech, Peter J Tonge
Elucidating the Signal Transduction Mechanism of the Blue-Light-Regulated Photoreceptor YtvA: From Photoactivation to Downstream Regulation. ACS chemical biology 19 (3) (2024)
Kaixuan Li, Alexa L Gilberti, Jocelyn A Marden, Hari K Akula, Alyssa C Pollard, Shuwen Guo, Bao Hu, Peter J Tonge, Wenchao Qu
Synthesis and Biological Evaluation of Fluorine-18 and Deuterium Labeled l-Fluoroalanines as Positron Emission Tomography Imaging Agents for Cancer Detection. Journal of medicinal chemistry 67 (12) (2024)
Kaixuan Li, Alexa L Gilberti, Jocelyn A Marden, Hari K Akula, Alyssa C Pollard, Shuwen Guo, Bao Hu, Peter J Tonge, Wenchao Qu
Synthesis and Biological Evaluation of Fluorine-18 and Deuterium Labeled l-Fluoroalanines as Positron Emission Tomography Imaging Agents for Cancer Detection. Journal of medicinal chemistry 67 (12) (2024)
Kaixuan Li, Jinnette Tolentino Collado, Jocelyn A Marden, Alyssa C Pollard, Shuwen Guo, Peter J Tonge, Wenchao Qu
Biological Evaluation of d-[ 18 F]Fluoroalanine and d-[ 18 F]Fluoroalanine- d 3 as Positron Emission Tomography Imaging Tracers for Bacterial Infection. Journal of medicinal chemistry 67 (16) (2024)
YongLe He, Jinnette Tolentino Collado, James N Iuliano, Helena A Woroniecka, Christopher R Hall, Agnieszka A Gil, Sergey P Laptenok, Gregory M Greetham, Boris Illarionov, Adelbert Bacher, Markus Fischer, Jarrod B French, Andras Lukacs, Stephen R Meech, Peter J Tonge
Elucidating the Signal Transduction Mechanism of the Blue-Light-Regulated Photoreceptor YtvA: From Photoactivation to Downstream Regulation. ACS chemical biology 19 (3) (2024)
Kaixuan Li, Jinnette Tolentino Collado, Jocelyn A Marden, Alyssa C Pollard, Shuwen Guo, Peter J Tonge, Wenchao Qu
Biological Evaluation of d-[ 18 F]Fluoroalanine and d-[ 18 F]Fluoroalanine- d 3 as Positron Emission Tomography Imaging Tracers for Bacterial Infection. Journal of medicinal chemistry (2024)
YongLe He, Jinnette Tolentino Collado, James N Iuliano, Helena A Woroniecka, Christopher R Hall, Agnieszka A Gil, Sergey P Laptenok, Gregory M Greetham, Boris Illarionov, Adelbert Bacher, Markus Fischer, Jarrod B French, Andras Lukacs, Stephen R Meech, Peter J Tonge
Elucidating the Signal Transduction Mechanism of the Blue-Light-Regulated Photoreceptor YtvA: From Photoactivation to Downstream Regulation. ACS chemical biology (2024)
Kaixuan Li, Jinnette Tolentino Collado, Jocelyn A Marden, Alyssa C Pollard, Shuwen Guo, Peter J Tonge, Wenchao Qu
Biological Evaluation of d-[ 18 F]Fluoroalanine and d-[ 18 F]Fluoroalanine- d 3 as Positron Emission Tomography Imaging Tracers for Bacterial Infection. Journal of medicinal chemistry (2024)
Kaixuan Li, Mingqian Wang, Melike Akoglu, Alyssa C Pollard, John B Klecker, Patricia Alfonso, Ana Corrionero, Niall Prendiville, Wenchao Qu, Matthew F L Parker, Nashaat Turkman, Jules A Cohen, Peter J Tonge
Synthesis and Preclinical Evaluation of a Novel Fluorine-18-Labeled Tracer for Positron Emission Tomography Imaging of Bruton's Tyrosine Kinase. ACS pharmacology & translational science 6 (3) (2023)
Kaixuan Li, Mingqian Wang, Melike Akoglu, Alyssa C Pollard, John B Klecker, Patricia Alfonso, Ana Corrionero, Niall Prendiville, Wenchao Qu, Matthew F L Parker, Nashaat Turkman, Jules A Cohen, Peter J Tonge
Synthesis and Preclinical Evaluation of a Novel Fluorine-18-Labeled Tracer for Positron Emission Tomography Imaging of Bruton's Tyrosine Kinase. ACS pharmacology & translational science 6 (3) (2023)
Mikhail Ignatov, Akhil Jindal, Sergei Kotelnikov, Dmitri Beglov, Ganna Posternak, Xiaojing Tang, Pierre Maisonneuve, Gennady Poda, Robert T Batey, Frank Sicheri, Adrian Whitty, Peter J Tonge, Sandor Vajda, Dima Kozakov
High Accuracy Prediction of PROTAC Complex Structures. Journal of the American Chemical Society (2023)
Yi-Qian Li, William G Lannigan, Shabnam Davoodi, Fereidoon Daryaee, Ana Corrionero, Patricia Alfonso, Jose A Rodriguez-Santamaria, Nan Wang, John D Haley, Peter J Tonge
Discovery of Novel Bruton's Tyrosine Kinase PROTACs with Enhanced Selectivity and Cellular Efficacy. Journal of medicinal chemistry (2023)
Shabnam Davoodi, Fereidoon Daryaee, James N Iuliano, Jinnette Tolentino Collado, YongLe He, Alyssa C Pollard, Agnieszka A Gil, James M Aramini, Peter J Tonge
Evaluating the Impact of the Tyr158 p K a on the Mechanism and Inhibition of InhA, the Enoyl-ACP Reductase from Mycobacterium tuberculosis . Biochemistry (2023)
Andras Lukacs, Peter J Tonge, Stephen R Meech
Photophysics of the Blue Light Using Flavin Domain. Accounts of chemical research 55 (3) (2022)
Sneha Basak, Yong Li, Suyuan Tao, Fereidoon Daryaee, Jonathan Merino, Chendi Gu, Silvia L Delker, Jenny N Phan, Thomas E Edwards, Stephen G Walker, Peter J Tonge
Structure-Kinetic Relationship Studies for the Development of Long Residence Time LpxC Inhibitors. Journal of medicinal chemistry 65 (17) (2022)
Jinnette Tolentino Collado, James N Iuliano, Katalin Pirisi, Samruddhi Jewlikar, Katrin Adamczyk, Gregory M Greetham, Michael Towrie, Jeremy R H Tame, Stephen R Meech, Peter J Tonge, Andras Lukacs
Unraveling the Photoactivation Mechanism of a Light-Activated Adenylyl Cyclase Using Ultrafast Spectroscopy Coupled with Unnatural Amino Acid Mutagenesis. ACS chemical biology 17 (9) (2022)
Matthew T Cifone, YongLe He, Rajeswari Basu, Nan Wang, Shabnam Davoodi, Lauren A Spagnuolo, Yuanyuan Si, Taraneh Daryaee, Craig E Stivala, Stephen G Walker, Peter J Tonge
Heterobivalent Inhibitors of Acetyl-CoA Carboxylase: Drug Target Residence Time and Time-Dependent Antibacterial Activity. Journal of medicinal chemistry (2022)
Rajeswari Basu, Nan Wang, Sneha Basak, Fereidoon Daryaee, Mustufa Babar, Eleanor K Allen, Stephen G Walker, John D Haley, Peter J Tonge
Impact of Target Turnover on the Translation of Drug-Target Residence Time to Time-Dependent Antibacterial Activity. ACS infectious diseases 7 (9) (2021)
Dale Green, Palas Roy, Christopher R Hall, James N Iuliano, Garth A Jones, Andras Lukacs, Peter J Tonge, Stephen R Meech
Excited State Resonance Raman of Flavin Mononucleotide: Comparison of Theory and Experiment. The journal of physical chemistry. A 125 (28) (2021)
Peter J Tonge
Featured Article Editorial. ACS infectious diseases 6 (12) (2020)
Iva Chitrakar, James N Iuliano, YongLe He, Helena A Woroniecka, Jinnette Tolentino Collado, Jinelle M Wint, Stephen G Walker, Peter J Tonge, Jarrod B French
Structural Basis for the Regulation of Biofilm Formation and Iron Uptake in A. baumannii by the Blue-Light-Using Photoreceptor, BlsA. ACS infectious diseases 6 (10) (2020)
James N Iuliano, Jinnette Tolentino Collado, Agnieszka A Gil, Pavithran T Ravindran, Andras Lukacs, SeungYoun Shin, Helena A Woroniecka, Katrin Adamczyk, James M Aramini, Uthama R Edupuganti, Christopher R Hall, Gregory M Greetham, Igor V Sazanovich, Ian P Clark, Taraneh Daryaee, Jared E Toettcher, Jarrod B French, Kevin H Gardner, Carlos L Simmerling, Stephen R Meech, Peter J Tonge
Unraveling the Mechanism of a LOV Domain Optogenetic Sensor: A Glutamine Lever Induces Unfolding of the Jα Helix. ACS chemical biology 15 (10) (2020)
Shabnam Davoodi, Fereidoon Daryaee, Andrew Chang, Stephen G Walker, Peter J Tonge
Correlating Drug-Target Residence Time and Post-antibiotic Effect: Insight into Target Vulnerability. ACS infectious diseases 6 (4) (2020)
Julia Fernández de Luco, Alejandro I Recio-Balsells, Diego G Ghiano, Ana Bortolotti, Juán Manuel Belardinelli, Nina Liu, Pascal Hoffmann, Christian Lherbet, Peter J Tonge, Babu Tekwani, Héctor Ricardo Morbidoni, Guillermo R Labadie
Exploring the chemical space of 1,2,3-triazolyl triclosan analogs for discovery of new antileishmanial chemotherapeutic agents. RSC medicinal chemistry 12 (1) (2020)
Yong Li, Fereidoon Daryaee, Grace E Yoon, Doyoung Noh, Peter M Smith-Jones, Yuanyuan Si, Stephen G Walker, Nashaat Turkman, Labros Meimetis, Peter J Tonge
Positron Emission Tomography Imaging of Staphylococcus aureus Infection Using a Nitro-Prodrug Analogue of 2-[18F]F-p-Aminobenzoic Acid. ACS infectious diseases 6 (8) (2020)
James N Iuliano, Christopher R Hall, Dale Green, Garth A Jones, Andras Lukacs, Boris Illarionov, Adelbert Bacher, Markus Fischer, Jarrod B French, Peter J Tonge, Stephen R Meech
Excited State Vibrations of Isotopically Labeled FMN Free and Bound to a Light-Oxygen-Voltage (LOV) Protein. The journal of physical chemistry. B 124 (33) (2020)
Peter J Tonge
Quantifying the Interactions between Biomolecules: Guidelines for Assay Design and Data Analysis. ACS infectious diseases 5 (6) (2019)
Christopher R Hall, Jinnette Tolentino Collado, James N Iuliano, Agnieszka A Gil, Katrin Adamczyk, Andras Lukacs, Gregory M Greetham, Igor Sazanovich, Peter J Tonge, Stephen R Meech
Site-Specific Protein Dynamics Probed by Ultrafast Infrared Spectroscopy of a Noncanonical Amino Acid. The journal of physical chemistry. B 123 (45) (2019)
Christopher E Evans, Yuanyuan Si, Joe S Matarlo, Yue Yin, Jarrod B French, Peter J Tonge, Derek S Tan
Structure-Based Design, Synthesis, and Biological Evaluation of Non-Acyl Sulfamate Inhibitors of the Adenylate-Forming Enzyme MenE. Biochemistry 58 (14) (2019)
Yuanyuan Si, Sneha Basak, Yong Li, Jonathan Merino, James N Iuliano, Stephen G Walker, Peter J Tonge
Antibacterial Activity and Mode of Action of a Sulfonamide-Based Class of Oxaborole Leucyl-tRNA-Synthetase Inhibitors. ACS infectious diseases 5 (7) (2019)
Sergey P Laptenok, Agnieszka A Gil, Christopher R Hall, Andras Lukacs, James N Iuliano, Garth A Jones, Gregory M Greetham, Paul Donaldson, Atsushi Miyawaki, Peter J Tonge, Stephen R Meech
Infrared spectroscopy reveals multi-step multi-timescale photoactivation in the photoconvertible protein archetype dronpa. Nature chemistry 10 (8) (2018)
James N Iuliano, Agnieszka A Gil, Sergey P Laptenok, Christopher R Hall, Jinnette Tolentino Collado, Andras Lukacs, Safaa A Hag Ahmed, Jenna Abyad, Taraneh Daryaee, Gregory M Greetham, Igor V Sazanovich, Boris Illarionov, Adelbert Bacher, Markus Fischer, Michael Towrie, Jarrod B French, Stephen R Meech, Peter J Tonge
Variation in LOV Photoreceptor Activation Dynamics Probed by Time-Resolved Infrared Spectroscopy. Biochemistry 57 (5) (2018)
Zhuo Zhang, Alvaro A Ordonez, Hui Wang, Yong Li, Kayla R Gogarty, Edward A Weinstein, Fereidoon Daryaee, Jonathan Merino, Grace E Yoon, Alvin S Kalinda, Ronnie C Mease, James N Iuliano, Peter M Smith-Jones, Sanjay K Jain, Peter J Tonge
Positron Emission Tomography Imaging with 2-[18F]F- p-Aminobenzoic Acid Detects Staphylococcus aureus Infections and Monitors Drug Response. ACS infectious diseases 4 (11) (2018)
Agnieszka A Gil, Sergey P Laptenok, James N Iuliano, Andras Lukacs, Anil Verma, Christopher R Hall, Grace E Yoon, Richard Brust, Gregory M Greetham, Michael Towrie, Jarrod B French, Stephen R Meech, Peter J Tonge
Photoactivation of the BLUF Protein PixD Probed by the Site-Specific Incorporation of Fluorotyrosine Residues. Journal of the American Chemical Society 139 (41) (2017)
Carla Neckles, Sandra Eltschkner, Jason E Cummings, Maria Hirschbeck, Fereidoon Daryaee, Gopal R Bommineni, Zhuo Zhang, Lauren Spagnuolo, Weixuan Yu, Shabnam Davoodi, Richard A Slayden, Caroline Kisker, Peter J Tonge
Rationalizing the Binding Kinetics for the Inhibition of the Burkholderia pseudomallei FabI1 Enoyl-ACP Reductase. Biochemistry 56 (13) (2017)
Fereidoon Daryaee, Zhuo Zhang, Kayla R Gogarty, Yong Li, Jonathan Merino, Stewart L Fisher, Peter J Tonge
A quantitative mechanistic PK/PD model directly connects Btk target engagement and in vivo efficacy. Chemical science 8 (5) (2017)
Lauren A Spagnuolo, Sandra Eltschkner, Weixuan Yu, Fereidoon Daryaee, Shabnam Davoodi, Susan E Knudson, Eleanor K H Allen, Jonathan Merino, Annica Pschibul, Ben Moree, Neil Thivalapill, James J Truglio, Joshua Salafsky, Richard A Slayden, Caroline Kisker, Peter J Tonge
Evaluating the Contribution of Transition-State Destabilization to Changes in the Residence Time of Triazole-Based InhA Inhibitors. Journal of the American Chemical Society 139 (9) (2017)
Peter J Tonge
Drug-Target Kinetics in Drug Discovery. ACS chemical neuroscience 9 (1) (2017)

Peter J Tonge.css-eqlu8i{font-size:small;padding-left:4px;} (Peter Tonge)

Publication Activity (10 Years)

Top Topics

Top Venues

Peter J Tonge (Peter Tonge)