Pierre Koch

Publication Activity (10 Years)

Years Active: 2017-2023
Publications (10 Years): 15

Top Topics

Molecular Dynamics Simulations

Photodynamic Therapy

Top Venues

Molecules (Basel, Switzerland)

Angewandte Chemie (International ed. in English)

Journal of medicinal chemistry

This page only lists publications with an associated author ORCID identifier.

Publications

Beate Sandra Hoffelner, Stanislav Andreev, Nicole Plank, Pierre Koch
Photocaging of Pyridinylimidazole-Based Covalent JNK3 Inhibitors Affords Spatiotemporal Control of the Binding Affinity in Live Cells. Pharmaceuticals (Basel, Switzerland) 16 (2) (2023)
Christoph Müller, Jakob Gleixner, Maris-Johanna Tahk, Sergei Kopanchuk, Tõnis Laasfeld, Michael Weinhart, Dieter Schollmeyer, Martin U Betschart, Steffen Lüdeke, Pierre Koch, Ago Rinken, Max Keller
Structure-Based Design of High-Affinity Fluorescent Probes for the Neuropeptide Y Y 1 Receptor. Journal of medicinal chemistry 65 (6) (2022)
Stanislav Andreev, Dieter Schollmeyer, Pierre Koch
1-{3-[(7-Fluoro-9 H -pyrimido[4,5- b ]indol-4-yl)(meth-yl)amino]-piperidin-1-yl}propan-1-one. IUCrData 6 (Pt 2) (2021)
Niklas M Tormählen, Mariella Martorelli, Annette Kuhn, Florian Maier, Jamil Guezguez, Michael Burnet, Wolfgang Albrecht, Stefan A Laufer, Pierre Koch
Design and Synthesis of Highly Selective Brain Penetrant p38α Mitogen-Activated Protein Kinase Inhibitors. Journal of medicinal chemistry (2021)
Alma Botas, Michael Eitel, Paul N Schwarz, Anina Buchmann, Paula Costales, Luz Elena Núñez, Jesús Cortés, Francisco Morís, Michał Krawiec, Marcin Wolański, Bertolt Gust, Mirna Rodriguez, Wolf-Nicolas Fischer, Bernd Jandeleit, Jolanta Zakrzewska-Czerwińska, Wolfgang Wohlleben, Evi Stegmann, Pierre Koch, Carmen Méndez, Harald Gross
Genetic Engineering in Combination with Semi-Synthesis Leads to a New Route for Gram-Scale Production of the Immunosuppressive Natural Product Brasilicardin A. Angewandte Chemie (International ed. in English) 60 (24) (2021)
Martin Reynders, Apirat Chaikuad, Benedict-Tilmann Berger, Katharina Bauer, Pierre Koch, Stefan A Laufer, Stefan Knapp, Dirk H Trauner
Controlling the Covalent Reactivity of a Kinase Inhibitor with Light. Angewandte Chemie (International ed. in English) 60 (37) (2021)
Stanislav Andreev, Tatu Pantsar, Roberta Tesch, Niclas Kahlke, Ahmed El-Gokha, Francesco Ansideri, Lukas Grätz, Jenny Romasco, Giulia Sita, Christian Geibel, Michael Lämmerhofer, Andrea Tarozzi, Stefan Knapp, Stefan A Laufer, Pierre Koch
Addressing a Trapped High-Energy Water: Design and Synthesis of Highly Potent Pyrimidoindole-Based Glycogen Synthase Kinase-3β Inhibitors. Journal of medicinal chemistry (2021)
Thomas Majer, Dieter Schollmeyer, Pierre Koch, Harald Gross
(2 S ,3' S ,3a' R ,5' R ,7a' R )-5'-[( E )-5-(Furan-3-yl)-2-methyl-pent-1-en-1-yl]-3-hy-droxy-3',4,7'-trimethyl-1',2',3',3a',5',7a'-hexa-hydro-5 H -spiro-[furan-2,4'-inden]-5-one. IUCrData 5 (Pt 12) (2020)
Stanislav Andreev, Tatu Pantsar, Ahmed El-Gokha, Francesco Ansideri, Mark Kudolo, Débora Bublitz Anton, Giulia Sita, Jenny Romasco, Christian Geibel, Michael Lämmerhofer, Márcia Ines Goettert, Andrea Tarozzi, Stefan A Laufer, Pierre Koch
Discovery and Evaluation of Enantiopure 9H-pyrimido[4,5-b]indoles as Nanomolar GSK-3β Inhibitors with Improved Metabolic Stability. International journal of molecular sciences 21 (21) (2020)
Stanislav Andreev, Tatu Pantsar, Francesco Ansideri, Mark Kudolo, Michael Forster, Dieter Schollmeyer, Stefan A Laufer, Pierre Koch
Design, Synthesis and Biological Evaluation of 7-Chloro-9H-pyrimido[4,5-b]indole-based Glycogen Synthase Kinase-3β Inhibitors. Molecules (Basel, Switzerland) 24 (12) (2019)
Francesco Ansideri, Stanislav Andreev, Annette Kuhn, Wolfgang Albrecht, Stefan A Laufer, Pierre Koch
A Diverse and Versatile Regiospecific Synthesis of Tetrasubstituted Alkylsulfanylimidazoles as p38α Mitogen-Activated Protein Kinase Inhibitors. Molecules (Basel, Switzerland) 23 (1) (2018)
Apirat Chaikuad, Pierre Koch, Stefan A Laufer, Stefan Knapp
The Cysteinome of Protein Kinases as a Target in Drug Development. Angewandte Chemie (International ed. in English) 57 (16) (2018)
Pierre Koch, Stefan A Laufer
Special Issue: Kinase inhibitors. Molecules (Basel, Switzerland) 23 (7) (2018)
Pierre Koch, Francesco Ansideri
2-Alkylsulfanyl-4(5)-aryl-5(4)-heteroarylimidazoles: An Overview on Synthetic Strategies and Biological Activity. Archiv der Pharmazie 350 (12) (2017)
Fabian Heider, Urs Haun, Eva Döring, Mark Kudolo, Catharina Sessler, Wolfgang Albrecht, Stefan Laufer, Pierre Koch
From 2-Alkylsulfanylimidazoles to 2-Alkylimidazoles: An Approach towards Metabolically More Stable p38α MAP Kinase Inhibitors. Molecules (Basel, Switzerland) 22 (10) (2017)