Rainer E Martin

ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 19

Top Venues

Angewandte Chemie (International ed. in English)

RSC medicinal chemistry

Journal of medicinal chemistry

Nature chemistry

F. Hoffmann-La Roche AG

This page only lists publications with an associated author ORCID identifier.

Affiliation History

F. Hoffmann-La Roche AG

Switzerland

Group Leader :: Medicinal Chemistry, Specialized Chemistry Technologies

F. Hoffmann-La Roche AG

Switzerland

Head of Laboratory :: Medicinal Chemistry, Oncology

F. Hoffmann-La Roche AG

Switzerland

Head of Laboratory :: Medicinal Chemistry, Chemical Biology

F. Hoffmann-La Roche AG

Switzerland

Head of Laboratory :: Discovery Chemistry, Chem. Technologies & Innovation

F. Hoffmann-La Roche AG

Switzerland

Head of Laboratory :: Discovery Chemistry, Medicinal Chemistry

F. Hoffmann-La Roche AG

Switzerland

Head of Laboratory :: Discovery Chemistry, Lead Generation

F. Hoffmann-La Roche AG

Switzerland

Head of Laboratory :: Formulation Research

Publications

Felix Gruber, Anthony W McDonagh, Victoria Rose, James H Hunter, Laura Guasch, Rainer E Martin, Stefanie N Geigle, Robert A Britton
sp 3 -Rich Heterocycle Synthesis on DNA: Application to DNA-Encoded Library Production. Angewandte Chemie (International ed. in English) 63 (12) (2024)
Kenneth Atz, David F Nippa, Alex T Müller, Vera Jost, Andrea Anelli, Michael Reutlinger, Christian Kramer, Rainer E Martin, Uwe Grether, Gisbert Schneider, Georg Wuitschik
Geometric deep learning-guided Suzuki reaction conditions assessment for applications in medicinal chemistry. RSC medicinal chemistry 15 (7) (2024)
Kenneth Atz, David F Nippa, Alex T Müller, Vera Jost, Andrea Anelli, Michael Reutlinger, Christian Kramer, Rainer E Martin, Uwe Grether, Gisbert Schneider, Georg Wuitschik
Geometric deep learning-guided Suzuki reaction conditions assessment for applications in medicinal chemistry. RSC medicinal chemistry 15 (7) (2024)
Felix Gruber, Anthony W McDonagh, Victoria Rose, James H Hunter, Laura Guasch, Rainer E Martin, Stefanie N Geigle, Robert A Britton
sp 3 -Rich Heterocycle Synthesis on DNA: Application to DNA-Encoded Library Production. Angewandte Chemie (International ed. in English) (2024)
Felix Gruber, Anthony W McDonagh, Victoria Rose, James H Hunter, Laura Guasch, Rainer E Martin, Stefanie N Geigle, Robert A Britton
sp 3 -Rich Heterocycle Synthesis on DNA: Application to DNA-Encoded Library Production. Angewandte Chemie (International ed. in English) 63 (12) (2024)
Felix Gruber, Anthony W McDonagh, Victoria Rose, James H Hunter, Laura Guasch, Rainer E Martin, Stefanie N Geigle, Robert A Britton
sp 3 -Rich Heterocycle Synthesis on DNA: Application to DNA-Encoded Library Production. Angewandte Chemie (International ed. in English) 63 (12) (2024)
Anne-Gaëlle Reinhart, Anja Osterwald, Philippe Ringler, Yael Leiser, Matthias E Lauer, Rainer E Martin, Christoph Ullmer, Felix F Schumacher, Claudia Korn, Michael Keller
Investigations into mRNA Lipid Nanoparticles Shelf-Life Stability under Nonfrozen Conditions. Molecular pharmaceutics (2023)
David F Nippa, Kenneth Atz, Remo Hohler, Alex T Müller, Andreas Marx, Christian Bartelmus, Georg Wuitschik, Irene Marzuoli, Vera Jost, Jens Wolfard, Martin Binder, Antonia F Stepan, David B Konrad, Uwe Grether, Rainer E Martin, Gisbert Schneider
Enabling late-stage drug diversification by high-throughput experimentation with geometric deep learning. Nature chemistry (2023)
Tatjana Sela, Mads Mansø, Michel Siegel, Céline Marban-Doran, Axel Ducret, Jens Niewöhner, Jacob Ravn, Rainer E Martin, Annika Sommer, Sabine Lohmann, Ben-Fillippo Krippendorff, Mette Ladefoged, Annette Indlekofer, Tom Quaiser, Florian Bueddefeld, Erich Koller, Mohamed Y Mohamed, Tobias Oelschlaegel, Kurt Vesterager Gothelf, Kerstin Hofer, Felix F Schumacher
Diligent Design Enables Antibody-ASO Conjugates with Optimal Pharmacokinetic Properties. Bioconjugate chemistry (2023)
David F Nippa, Kenneth Atz, Alex T Müller, Jens Wolfard, Clemens Isert, Martin Binder, Oliver Scheidegger, David B Konrad, Uwe Grether, Rainer E Martin, Gisbert Schneider
Identifying opportunities for late-stage C-H alkylation with high-throughput experimentation and in silico reaction screening. Communications chemistry 6 (1) (2023)
Josiah J Newton, Benson J Jelier, Michael Meanwell, Rainer E Martin, Robert A Britton, Chadron M Friesen
Quaternary Ammonium Trifluoromethoxide Salts as Stable Sources of Nucleophilic OCF3. Organic letters 22 (5) (2020)
Josiah J Newton, Daniel Driedger, Matthew B Nodwell, Paul Schaffer, Rainer E Martin, Robert A Britton, Chadron M Friesen
A Convenient Synthesis of Difluoroalkyl Ethers from Thionoesters Using Silver(I) Fluoride. Chemistry (Weinheim an der Bergstrasse, Germany) (2019)
Maude Giroud, Bernd Kuhn, Sarah Saint-Auret, Christoph Kuratli, Rainer E Martin, Franz Schuler, François Diederich, Marcel Kaiser, Reto Brun, Tanja Schirmeister, Wolfgang Haap
2 H-1,2,3-Triazole-Based Dipeptidyl Nitriles: Potent, Selective, and Trypanocidal Rhodesain Inhibitors by Structure-Based Design. Journal of medicinal chemistry 61 (8) (2018)
Michael Meanwell, Bharani Shashank Adluri, Zheliang Yuan, Josiah J Newton, Philippe Prevost, Matthew B Nodwell, Chadron M Friesen, Paul Schaffer, Rainer E Martin, Robert A Britton
Direct heterobenzylic fluorination, difluorination and trifluoromethylthiolation with dibenzenesulfonamide derivatives. Chemical science 9 (25) (2018)
Michael Meanwell, Johannes Lehmann, Marc Eichenberger, Rainer E Martin, Robert A Britton
Synthesis of acyl fluorides via photocatalytic fluorination of aldehydic C-H bonds. Chemical communications (Cambridge, England) 54 (71) (2018)
Zheliang Yuan, Matthew B Nodwell, Hua Yang, Noeen Malik, Helen Merkens, François Bénard, Rainer E Martin, Paul Schaffer, Robert A Britton
Site-Selective, Late-Stage C-H 18 F-Fluorination on Unprotected Peptides for Positron Emission Tomography Imaging. Angewandte Chemie (International ed. in English) 57 (39) (2018)
Guillaume Duret, Robert Quinlan, Boyang Yin, Rainer E Martin, Philippe Bisseret, Markus Neuburger, Vincent Gandon, Nicolas Blanchard
Intramolecular Inverse Electron-Demand [4 + 2] Cycloadditions of Ynamides with Pyrimidines: Scope and Density Functional Theory Insights. The Journal of organic chemistry 82 (3) (2017)
Matthew B Nodwell, Hua Yang, Milena Čolović, Zheliang Yuan, Helen Merkens, Rainer E Martin, François Bénard, Paul Schaffer, Robert A Britton
18F-Fluorination of Unactivated C-H Bonds in Branched Aliphatic Amino Acids: Direct Synthesis of Oncological Positron Emission Tomography Imaging Agents. Journal of the American Chemical Society 139 (10) (2017)
Bernd Kuhn, Michal Tichý, Lingle Wang, Shaughnessy Robinson, Rainer E Martin, Andreas Kuglstatter, Jörg Benz, Maude Giroud, Tanja Schirmeister, Robert Abel, François Diederich, Jérôme Hert
Prospective Evaluation of Free Energy Calculations for the Prioritization of Cathepsin L Inhibitors. Journal of medicinal chemistry 60 (6) (2017)

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Publication Activity (10 Years)

Top Topics

Top Venues

Rainer E Martin