Antonia F Stepan

Publication Activity (10 Years)

Years Active: 2017-2023
Publications (10 Years): 6

Top Topics

Induced Pluripotent Stem Cells

Magnetic Resonance

Top Venues

Journal of medicinal chemistry

Nature chemistry

ACS medicinal chemistry letters

This page only lists publications with an associated author ORCID identifier.

Publications

David F Nippa, Kenneth Atz, Remo Hohler, Alex T Müller, Andreas Marx, Christian Bartelmus, Georg Wuitschik, Irene Marzuoli, Vera Jost, Jens Wolfard, Martin Binder, Antonia F Stepan, David B Konrad, Uwe Grether, Rainer E Martin, Gisbert Schneider
Enabling late-stage drug diversification by high-throughput experimentation with geometric deep learning. Nature chemistry (2023)
Giuseppe Cecere, Laura Guasch, Andres M Olivares-Morales, Kenichi Umehara, Antonia F Stepan
LipMetE (Lipophilic Metabolism Efficiency) as a Simple Guide for Half-Life and Dosing Regimen Prediction of Oral Drugs. ACS medicinal chemistry letters 13 (9) (2022)
Peter S Dragovich, Wolfgang Haap, Melinda M Mulvihill, Jean-Marc Plancher, Antonia F Stepan
Small-Molecule Lead-Finding Trends across the Roche and Genentech Research Organizations. Journal of medicinal chemistry 65 (4) (2022)
Alessio Ciulli, Lawrence Hamann, Wolfgang Jahnke, Amit S Kalgutkar, Thomas Magauer, Tobias Ritter, Vicky Steadman, Scott D Williams, Georg E Winter, Klemens Hoegenauer, Karl Heinz Krawinkler, Antonia F Stepan
The 2nd Alpine Winter Conference on Medicinal and Synthetic Chemistry. ChemMedChem 16 (15) (2021)
R Scott Obach, Gregory S Walker, Raman Sharma, Stephen Jenkinson, Tuan P Tran, Antonia F Stepan
Lead Diversification at the Nanomole Scale Using Liver Microsomes and Quantitative Nuclear Magnetic Resonance Spectroscopy: Application to Phosphodiesterase 2 Inhibitors. Journal of medicinal chemistry 61 (8) (2018)
Antonia F Stepan, Michelle M Claffey, Matthew R Reese, Gayatri Balan, Gabriela Barreiro, Jason Barricklow, Michael J Bohanon, Brian P Boscoe, Gregg D Cappon, Lois K Chenard, Julie Cianfrogna, Laigao Chen, Karen J Coffman, Susan E Drozda, Joshua R Dunetz, Somraj Ghosh, Xinjun Hou, Christopher Houle, Kapil Karki, John T Lazzaro, Jessica Y Mancuso, John M Marcek, Emily L Miller, Mark A Moen, Steven O'Neil, Isao Sakurada, Marc Skaddan, Vinod Parikh, Deborah L Smith, Patrick Trapa, Jamison B Tuttle, Patrick R Verhoest, Daniel P Walker, Annie Won, Ann S Wright, Jessica Whritenour, Kenneth Zasadny, Margaret M Zaleska, Lei Zhang, Christopher L Shaffer
Discovery and Characterization of (R)-6-Neopentyl-2-(pyridin-2-ylmethoxy)-6,7-dihydropyrimido[2,1-c][1,4]oxazin-4(9H)-one (PF-06462894), an Alkyne-Lacking Metabotropic Glutamate Receptor 5 Negative Allosteric Modulator Profiled in both Rat and Nonhuman Primates. Journal of medicinal chemistry 60 (18) (2017)