Rens de Groot

Loop profile ORCID

Publication Activity (10 Years)

Years Active: 2015-2024
Publications (10 Years): 13

Top Topics

Rheumatoid Arthritis

Structural Basis

Extracorporeal Membrane Oxygenation

Cardiovascular Risk Factors

Top Venues

RSC medicinal chemistry

Scientific reports

This page only lists publications with an associated author ORCID identifier.

Publications

Nithya Prasannan, Bertina Dragunaite, Maryam Subhan, Mari Thomas, Rens de Groot, Deepak Singh, Karen Vanhoorelbeke, Marie Scully
Peak ADAMTS13 activity to assess ADAMTS13 conformation and risk of relapse in immune-mediated thrombotic thrombocytopenic purpura. Blood 143 (25) (2024)
Doretta Cuffaro, Tina Burkhard, Bianca Laura Bernardoni, Riccardo Di Leo, Xiaohan Zhang, Salvatore Galati, Tiziano Tuccinardi, Marco Macchia, Armando Rossello, Salvatore Santamaria, Rens de Groot, Elisa Nuti
Design, synthesis and biological evaluation of arylsulfonamides as ADAMTS7 inhibitors. RSC medicinal chemistry 15 (8) (2024)
Doretta Cuffaro, Tina Burkhard, Bianca Laura Bernardoni, Riccardo Di Leo, Xiaohan Zhang, Salvatore Galati, Tiziano Tuccinardi, Marco Macchia, Armando Rossello, Salvatore Santamaria, Rens de Groot, Elisa Nuti
Design, synthesis and biological evaluation of arylsulfonamides as ADAMTS7 inhibitors. RSC medicinal chemistry 15 (8) (2024)
Nithya Prasannan, Bertina Dragunaite, Maryam Owais Subhan, Mari Thomas, Rens de Groot, Deepak Singh, Karen Vanhoorelbeke, Marie Scully
Peak ADAMTS13 activity to assess ADAMTS13 conformation and risk of relapse in immune-mediated Thrombotic Thrombocytopenic Purpura. Blood (2024)
Nithya Prasannan, Bertina Dragunaite, Maryam Owais Subhan, Mari Thomas, Rens de Groot, Deepak Singh, Karen Vanhoorelbeke, Marie Scully
Peak ADAMTS13 activity to assess ADAMTS13 conformation and risk of relapse in immune-mediated Thrombotic Thrombocytopenic Purpura. Blood (2024)
Nithya Prasannan, Mari Thomas, Matthew James Stubbs, John-Paul Westwood, Rens de Groot, Deepak Singh, Marie Scully
Delayed normalisation of ADAMTS13 activity in acute Thrombotic Thrombocytopenic Purpura in the caplacizumab era. Blood (2023)
Nithya Prasannan, Mari Thomas, Matthew James Stubbs, John-Paul Westwood, Rens de Groot, Deepak Singh, Marie Scully
Delayed normalisation of ADAMTS13 activity in acute Thrombotic Thrombocytopenic Purpura in the caplacizumab era. Blood (2023)
Salvatore Santamaria, Frederic Buemi, Elisa Nuti, Doretta Cuffaro, Elena De Vita, Tiziano Tuccinardi, Armando Rossello, Steven Howell, Shahid Mehmood, Ambrosius P Snijders, Rens de Groot
Development of a fluorogenic ADAMTS-7 substrate. Journal of enzyme inhibition and medicinal chemistry 36 (1) (2022)
Jin-Sup Shin, Maryam Owais Subhan, Geraldine Cambridge, Yanping Guo, Rens de Groot, Marie Scully, Marie Scully
Alterations in B- and circulating T-follicular helper cell subsets in immune thrombotic thrombocytopenic purpura. Blood advances 6 (12) (2022)
Anastasis Petri, Hyo Jung Kim, Yaoxian Xu, Rens de Groot, Chan Li, Aline Vandenbulcke, Karen Vanhoorelbeke, Jonas Emsley, James T B Crawley
Crystal structure and substrate-induced activation of ADAMTS13. Nature communications 10 (1) (2019)
Salvatore Santamaria, Kazuhiro Yamamoto, Adrienn Teraz-Orosz, Christopher Koch, Suneel S Apte, Rens de Groot, David A Lane, Josefin Ahnström
Exosites in Hypervariable Loops of ADAMTS Spacer Domains control Substrate Recognition and Proteolysis. Scientific reports 9 (1) (2019)
Salvatore Santamaria, Rens de Groot
Monoclonal antibodies against metzincin targets. British journal of pharmacology 176 (1) (2018)
Rens de Groot, David A Lane, James T B Crawley
The role of the ADAMTS13 cysteine-rich domain in VWF binding and proteolysis. Blood 125 (12) (2015)