Reuben J Shaw (Reuben Shaw)

ORCID

Publication Activity (10 Years)

Years Active: 2019-2024
Publications (10 Years): 35

Top Venues

Science advances

Science (New York, N.Y.)

Cancer discovery

Nature communications

Salk Institute for Biological Studies

Massachusetts Institute of Technology (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Salk Institute for Biological Studies Jan 01 2006

United States

Professor :: Molecular and Cell Biology Laboratory

Education History

Massachusetts Institute of Technology

United States

PHD :: Biology

Cornell University

United States

BSC :: Biological Sciences

Publications

Alexandra Kuhlmann-Hogan, Thekla Cordes, Ziyan Xu, Ramya S Kuna, Kacie A Traina, Camila Robles-Oteíza, Deborah Ayeni, Elizabeth M Kwong, Stellar Levy, Anna-Maria Globig, Matthew M Nobari, George Z Cheng, Sandra L Leibel, Robert J Homer, Reuben J Shaw, Christian M Metallo, Katerina Politi, Susan M Kaech
EGFR-driven lung adenocarcinomas coopt alveolar macrophage metabolism and function to support EGFR signaling and growth. Cancer discovery (2024)
Alexandra Kuhlmann-Hogan, Thekla Cordes, Ziyan Xu, Ramya S Kuna, Kacie A Traina, Camila Robles-Oteíza, Deborah Ayeni, Elizabeth M Kwong, Stellar Levy, Anna-Maria Globig, Matthew M Nobari, George Z Cheng, Sandra L Leibel, Robert J Homer, Reuben J Shaw, Christian M Metallo, Katerina Politi, Susan M Kaech
EGFR-driven lung adenocarcinomas coopt alveolar macrophage metabolism and function to support EGFR signaling and growth. Cancer discovery (2024)
Alexandra Kuhlmann-Hogan, Thekla Cordes, Ziyan Xu, Ramya S Kuna, Kacie A Traina, Camila Robles-Oteíza, Deborah Ayeni, Elizabeth M Kwong, Stellar Levy, Anna-Maria Globig, Matthew M Nobari, George Z Cheng, Sandra L Leibel, Robert J Homer, Reuben J Shaw, Christian M Metallo, Katerina Politi, Susan M Kaech
EGFR-Driven Lung Adenocarcinomas Co-opt Alveolar Macrophage Metabolism and Function to Support EGFR Signaling and Growth. Cancer discovery (2024)
Alexandra Kuhlmann-Hogan, Thekla Cordes, Ziyan Xu, Ramya S Kuna, Kacie A Traina, Camila Robles-Oteíza, Deborah Ayeni, Elizabeth M Kwong, Stellar Levy, Anna-Maria Globig, Matthew M Nobari, George Z Cheng, Sandra L Leibel, Robert J Homer, Reuben J Shaw, Christian M Metallo, Katerina Politi, Susan M Kaech
EGFR-driven lung adenocarcinomas coopt alveolar macrophage metabolism and function to support EGFR signaling and growth. Cancer discovery (2024)
Alexandra Kuhlmann-Hogan, Thekla Cordes, Ziyan Xu, Ramya S Kuna, Kacie A Traina, Camila Robles-Oteíza, Deborah Ayeni, Elizabeth M Kwong, Stellar Levy, Anna-Maria Globig, Matthew M Nobari, George Z Cheng, Sandra L Leibel, Robert J Homer, Reuben J Shaw, Christian M Metallo, Katerina Politi, Susan M Kaech
EGFR-driven lung adenocarcinomas coopt alveolar macrophage metabolism and function to support EGFR signaling and growth. Cancer discovery (2024)
Alexandra Kuhlmann-Hogan, Thekla Cordes, Ziyan Xu, Ramya S Kuna, Kacie A Traina, Camila Robles-Oteíza, Deborah Ayeni, Elizabeth M Kwong, Stellar Levy, Anna-Maria Globig, Matthew M Nobari, George Z Cheng, Sandra L Leibel, Robert J Homer, Reuben J Shaw, Christian M Metallo, Katerina Politi, Susan M Kaech
EGFR-driven lung adenocarcinomas coopt alveolar macrophage metabolism and function to support EGFR signaling and growth. Cancer discovery (2024)
Alexandra Kuhlmann-Hogan, Thekla Cordes, Ziyan Xu, Ramya S Kuna, Kacie A Traina, Camila Robles-Oteíza, Deborah Ayeni, Elizabeth M Kwong, Stellar Levy, Anna-Maria Globig, Matthew M Nobari, George Z Cheng, Sandra L Leibel, Robert J Homer, Reuben J Shaw, Christian M Metallo, Katerina Politi, Susan M Kaech
EGFR-driven lung adenocarcinomas coopt alveolar macrophage metabolism and function to support EGFR signaling and growth. Cancer discovery (2024)
Alexandra Kuhlmann-Hogan, Thekla Cordes, Ziyan Xu, Ramya S Kuna, Kacie A Traina, Camila Robles-Oteíza, Deborah Ayeni, Elizabeth M Kwong, Stellar Levy, Anna-Maria Globig, Matthew M Nobari, George Z Cheng, Sandra L Leibel, Robert J Homer, Reuben J Shaw, Christian M Metallo, Katerina Politi, Susan M Kaech
EGFR-driven lung adenocarcinomas coopt alveolar macrophage metabolism and function to support EGFR signaling and growth. Cancer discovery (2024)
Nazma Malik, Bibiana I Ferreira, Pablo E Hollstein, Stephanie D Curtis, Elijah Trefts, Sammy Weiser Novak, Jingting Yu, Rebecca Gilson, Kristina Hellberg, Lingjing Fang, Arlo Sheridan, Nasun Hah, Gerald S Shadel, Uri Manor, Reuben J Shaw
Induction of lysosomal and mitochondrial biogenesis by AMPK phosphorylation of FNIP1. Science (New York, N.Y.) 380 (6642) (2023)
Lillian J Eichner, Stephanie D Curtis, Sonja N Brun, Caroline K McGuire, Irena Gushterova, Joshua T Baumgart, Elijah Trefts, Debbie S Ross, Tammy J Rymoff, Reuben J Shaw
HDAC3 is critical in tumor development and therapeutic resistance in Kras -mutant non-small cell lung cancer. Science advances 9 (11) (2023)
Ramya S Kuna, Avi Kumar, Karl A Wessendorf-Rodriguez, Hector M Galvez, Courtney R Green, Grace H McGregor, Thekla Cordes, Reuben J Shaw, Robert U Svensson, Christian M Metallo
Inter-organelle cross-talk supports acetyl-coenzyme A homeostasis and lipogenesis under metabolic stress. Science advances 9 (18) (2023)
Ramya S Kuna, Avi Kumar, Karl A Wessendorf-Rodriguez, Hector M Galvez, Courtney R Green, Grace H McGregor, Thekla Cordes, Reuben J Shaw, Robert U Svensson, Christian M Metallo
Inter-organelle cross-talk supports acetyl-coenzyme A homeostasis and lipogenesis under metabolic stress. Science advances 9 (18) (2023)
Lillian J Eichner, Stephanie D Curtis, Sonja N Brun, Caroline K McGuire, Irena Gushterova, Joshua T Baumgart, Elijah Trefts, Debbie S Ross, Tammy J Rymoff, Reuben J Shaw
HDAC3 is critical in tumor development and therapeutic resistance in Kras -mutant non-small cell lung cancer. Science advances 9 (11) (2023)
Nazma Malik, Bibiana I Ferreira, Pablo E Hollstein, Stephanie D Curtis, Elijah Trefts, Sammy Weiser Novak, Jingting Yu, Rebecca Gilson, Kristina Hellberg, Lingjing Fang, Arlo Sheridan, Nasun Hah, Gerald S Shadel, Uri Manor, Reuben J Shaw
Induction of lysosomal and mitochondrial biogenesis by AMPK phosphorylation of FNIP1. Science (New York, N.Y.) 380 (6642) (2023)
Nazma Malik, Bibiana I Ferreira, Pablo E Hollstein, Stephanie D Curtis, Elijah Trefts, Sammy Weiser Novak, Jingting Yu, Rebecca Gilson, Kristina Hellberg, Lingjing Fang, Arlo Sheridan, Nasun Hah, Gerald S Shadel, Uri Manor, Reuben J Shaw
Induction of lysosomal and mitochondrial biogenesis by AMPK phosphorylation of FNIP1. Science (New York, N.Y.) 380 (6642) (2023)
Tao Zhang, Daichao Xu, Elijah Trefts, Mingming Lv, Hiroyuki Inuzuka, Guobin Song, Min Liu, Jianlin Lu, Jianping Liu, Chen Chu, Min Wang, Huibing Wang, Huyan Meng, Hui Liu, Yuan Zhuang, Xingxing Xie, Fabin Dang, Dongxian Guan, Yuqin Men, Shuwen Jiang, Cong Jiang, Xiaoming Dai, Jing Liu, Zhen Wang, Peiqiang Yan, Jingchao Wang, Zhenbo Tu, Mrigya Babuta, Emily C Erickson, Alissandra L Hillis, Christian C Dibble, John M Asara, Gyongyi Szabo, Piotr Sicinski, Ji Miao, Yu-Ru Lee, Lifeng Pan, Reuben J Shaw, Junying Yuan, Wenyi Wei
Metabolic orchestration of cell death by AMPK-mediated phosphorylation of RIPK1. Science (New York, N.Y.) 380 (6652) (2023)
Lillian J Eichner, Stephanie D Curtis, Sonja N Brun, Caroline K McGuire, Irena Gushterova, Joshua T Baumgart, Elijah Trefts, Debbie S Ross, Tammy J Rymoff, Reuben J Shaw
HDAC3 is critical in tumor development and therapeutic resistance in Kras -mutant non-small cell lung cancer. Science advances 9 (11) (2023)
Lillian J Eichner, Stephanie D Curtis, Sonja N Brun, Caroline K McGuire, Irena Gushterova, Joshua T Baumgart, Elijah Trefts, Debbie S Ross, Tammy J Rymoff, Reuben J Shaw
HDAC3 is critical in tumor development and therapeutic resistance in Kras -mutant non-small cell lung cancer. Science advances 9 (11) (2023)
Nazma Malik, Bibiana I Ferreira, Pablo E Hollstein, Stephanie D Curtis, Elijah Trefts, Sammy Weiser Novak, Jingting Yu, Rebecca Gilson, Kristina Hellberg, Lingjing Fang, Arlo Sheridan, Nasun Hah, Gerald S Shadel, Uri Manor, Reuben J Shaw
Induction of lysosomal and mitochondrial biogenesis by AMPK phosphorylation of FNIP1. Science (New York, N.Y.) 380 (6642) (2023)
Nazma Malik, Bibiana I Ferreira, Pablo E Hollstein, Stephanie D Curtis, Elijah Trefts, Sammy Weiser Novak, Jingting Yu, Rebecca Gilson, Kristina Hellberg, Lingjing Fang, Arlo Sheridan, Nasun Hah, Gerald S Shadel, Uri Manor, Reuben J Shaw
Induction of lysosomal and mitochondrial biogenesis by AMPK phosphorylation of FNIP1. Science (New York, N.Y.) 380 (6642) (2023)
Nazma Malik, Bibiana I Ferreira, Pablo E Hollstein, Stephanie D Curtis, Elijah Trefts, Sammy Weiser Novak, Jingting Yu, Rebecca Gilson, Kristina Hellberg, Lingjing Fang, Arlo Sheridan, Nasun Hah, Gerald S Shadel, Uri Manor, Reuben J Shaw
Induction of lysosomal and mitochondrial biogenesis by AMPK phosphorylation of FNIP1. Science (New York, N.Y.) 380 (6642) (2023)
Ramya S Kuna, Avi Kumar, Karl A Wessendorf-Rodriguez, Hector M Galvez, Courtney R Green, Grace H McGregor, Thekla Cordes, Reuben J Shaw, Robert U Svensson, Christian M Metallo
Inter-organelle cross-talk supports acetyl-coenzyme A homeostasis and lipogenesis under metabolic stress. Science advances 9 (18) (2023)
Benjamin D Stein, John R Ferrarone, Eric E Gardner, Jae Won Chang, David Wu, Pablo E Hollstein, Roger J Liang, Min Yuan, Qiuying Chen, John S Coukos, Miriam Sindelar, Bryan Ngo, Steven S Gross, Reuben J Shaw, Chen Zhang, John M Asara, Raymond E Moellering, Harold Varmus, Lewis C Cantley
LKB1-dependent regulation of TPI1 creates a divergent metabolic liability between human and mouse lung adenocarcinoma. Cancer discovery (2023)
Tao Zhang, Daichao Xu, Elijah Trefts, Mingming Lv, Hiroyuki Inuzuka, Guobin Song, Min Liu, Jianlin Lu, Jianping Liu, Chen Chu, Min Wang, Huibing Wang, Huyan Meng, Hui Liu, Yuan Zhuang, Xingxing Xie, Fabin Dang, Dongxian Guan, Yuqin Men, Shuwen Jiang, Cong Jiang, Xiaoming Dai, Jing Liu, Zhen Wang, Peiqiang Yan, Jingchao Wang, Zhenbo Tu, Mrigya Babuta, Emily C Erickson, Alissandra L Hillis, Christian C Dibble, John M Asara, Gyongyi Szabo, Piotr Sicinski, Ji Miao, Yu-Ru Lee, Lifeng Pan, Reuben J Shaw, Junying Yuan, Wenyi Wei
Metabolic orchestration of cell death by AMPK-mediated phosphorylation of RIPK1. Science (New York, N.Y.) 380 (6652) (2023)
Tao Zhang, Daichao Xu, Elijah Trefts, Mingming Lv, Hiroyuki Inuzuka, Guobin Song, Min Liu, Jianlin Lu, Jianping Liu, Chen Chu, Min Wang, Huibing Wang, Huyan Meng, Hui Liu, Yuan Zhuang, Xingxing Xie, Fabin Dang, Dongxian Guan, Yuqin Men, Shuwen Jiang, Cong Jiang, Xiaoming Dai, Jing Liu, Zhen Wang, Peiqiang Yan, Jingchao Wang, Zhenbo Tu, Mrigya Babuta, Emily C Erickson, Alissandra L Hillis, Christian C Dibble, John M Asara, Gyongyi Szabo, Piotr Sicinski, Ji Miao, Yu-Ru Lee, Lifeng Pan, Reuben J Shaw, Junying Yuan, Wenyi Wei
Metabolic orchestration of cell death by AMPK-mediated phosphorylation of RIPK1. Science (New York, N.Y.) 380 (6652) (2023)
Ramya S Kuna, Avi Kumar, Karl A Wessendorf-Rodriguez, Hector M Galvez, Courtney R Green, Grace H McGregor, Thekla Cordes, Reuben J Shaw, Robert U Svensson, Christian M Metallo
Inter-organelle cross-talk supports acetyl-coenzyme A homeostasis and lipogenesis under metabolic stress. Science advances 9 (18) (2023)
Nazma Malik, Bibiana I Ferreira, Pablo E Hollstein, Stephanie D Curtis, Elijah Trefts, Sammy Weiser Novak, Jingting Yu, Rebecca Gilson, Kristina Hellberg, Lingjing Fang, Arlo Sheridan, Nasun Hah, Gerald S Shadel, Uri Manor, Reuben J Shaw
Induction of lysosomal and mitochondrial biogenesis by AMPK phosphorylation of FNIP1. Science (New York, N.Y.) 380 (6642) (2023)
Danielle L Schmitt, Stephanie D Curtis, Anne C Lyons, Jin-Fan Zhang, Mingyuan Chen, Catherine Y He, Sohum Mehta, Reuben J Shaw, Jin Zhang
Spatial regulation of AMPK signaling revealed by a sensitive kinase activity reporter. Nature communications 13 (1) (2022)
Marie Pariollaud, Lara H Ibrahim, Emanuel Irizarry, Rebecca M Mello, Alanna B Chan, Brian J Altman, Reuben J Shaw, Michael J Bollong, R Luke Wiseman, Katja A Lamia
Circadian disruption enhances HSF1 signaling and tumorigenesis in Kras -driven lung cancer. Science advances 8 (39) (2022)
Annie Lee, Chandana Kondapalli, Daniel M Virga, Tommy L Lewis, So Yeon Koo, Archana Ashok, Georges Mairet-Coello, Sebastien Herzig, Marc Foretz, Benoit Viollet, Reuben J Shaw, Andrew Sproul, Franck Polleux
Aβ42 oligomers trigger synaptic loss through CAMKK2-AMPK-dependent effectors coordinating mitochondrial fission and mitophagy. Nature communications 13 (1) (2022)
Caryn Lerman, Chanita Hughes Halbert, Mary Falcone, David M Gosky, Roy A Jensen, Kelvin P Lee, Edith P Mitchell, Kunle Odunsi, Jennifer W Pegher, Elisa Rodriguez, Yolanda Sanchez, Reuben J Shaw, George J Weiner, Cheryl L Willman
Leadership Diversity and Development in the Nation's Cancer Centers. Journal of the National Cancer Institute 114 (9) (2022)
Esther W Lim, Michal K Handzlik, Elijah Trefts, Jivani M Gengatharan, Carlos M Pondevida, Reuben J Shaw, Christian M Metallo
Progressive alterations in amino acid and lipid metabolism correlate with peripheral neuropathy in PolgD257A mice. Science advances 7 (42) (2021)
Chien-Min Hung, Portia S Lombardo, Nazma Malik, Sonja N Brun, Kristina Hellberg, Jeanine L Van Nostrand, Daniel Garcia, Joshua Baumgart, Ken Diffenderfer, John M Asara, Reuben J Shaw
AMPK/ULK1-mediated phosphorylation of Parkin ACT domain mediates an early step in mitophagy. Science advances 7 (15) (2021)
Jeanine L Van Nostrand, Kristina Hellberg, En-Ching Luo, Eric L Van Nostrand, Alina Dayn, Jingting Yu, Maxim N Shokhirev, Yelena Dayn, Gene W Yeo, Reuben J Shaw
AMPK regulation of Raptor and TSC2 mediate metformin effects on transcriptional control of anabolism and inflammation. Genes & development 34 (19-20) (2020)
Laura Rodón, Robert U Svensson, Ezra Wiater, Matthew G H Chun, Wen-Wei Tsai, Lillian J Eichner, Reuben J Shaw, Marc Montminy
The CREB coactivator CRTC2 promotes oncogenesis in LKB1-mutant non-small cell lung cancer. Science advances 5 (7) (2019)

Reuben J Shaw.css-eqlu8i{font-size:small;padding-left:4px;} (Reuben Shaw)

Publication Activity (10 Years)

Top Topics

Top Venues

Reuben J Shaw (Reuben Shaw)