R Luke Wiseman

Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 72

Top Venues

bioRxiv : the preprint server for biology

ACS chemical biology

The Journal of cell biology

Proceedings of the National Academy of Sciences of the United States of America

The Scripps Research Institute

Scripps Research Institute (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

The Scripps Research Institute

United States

Associate Professor :: Department of Molecular Medicine

Scripps Research Institute

United States

Assistant Professor :: Department of Molecular & Experimental Medicine, Department of Chemical Physiology

New York University Skirball Institute of Biomolecular Medicine

United States

Postdoctoral Research Associate

Education History

Scripps Research Institute

United States

PHD :: Department of Chemistry

University of Virginia

United States

BSC :: Department of Chemistry

Publications

Caroline Stanton, Jie Sun, Kayla Nutsch, Jessica D Rosarda, Thu Nguyen, Chloris Li-Ma, Evert Njomen, Bruno Melillo, Sergei Kutseikin, Enrique Saez, Benjamin F Cravatt, John R Teijaro, R Luke Wiseman, Michael J Bollong
Covalent Targeting As a Common Mechanism for Inhibiting NLRP3 Inflammasome Assembly. ACS chemical biology 19 (2) (2024)
Nicole Madrazo, Zinia Khattar, Evan T Powers, Jessica D Rosarda, R Luke Wiseman
Mapping Stress-Responsive Signaling Pathways Induced by Mitochondrial Proteostasis Perturbations. bioRxiv : the preprint server for biology (2024)
Nicole Madrazo, Zinia Khattar, Evan T Powers, Jessica D Rosarda, R Luke Wiseman
Mapping stress-responsive signaling pathways induced by mitochondrial proteostasis perturbations. Molecular biology of the cell 35 (5) (2024)
Kelsey R Baron, Samantha Oviedo, Sophia Krasny, Mashiat Zaman, Rama Aldakhlallah, Prakhyat Mathur, Gerald Pfeffer, Michael J Bollong, Timothy E Shutt, Danielle A Grotjahn, R Luke Wiseman
Pharmacologic Activation of Integrated Stress Response Kinases Inhibits Pathologic Mitochondrial Fragmentation. bioRxiv : the preprint server for biology (2024)
Kelsey R Baron, Samantha Oviedo, Sophia Krasny, Mashiat Zaman, Rama Aldakhlallah, Prakhyat Mathur, Gerald Pfeffer, Michael J Bollong, Timothy E Shutt, Danielle A Grotjahn, R Luke Wiseman
Pharmacologic Activation of Integrated Stress Response Kinases Inhibits Pathologic Mitochondrial Fragmentation. bioRxiv : the preprint server for biology (2024)
Nicole Madrazo, Zinia Khattar, Evan T Powers, Jessica D Rosarda, R Luke Wiseman
Mapping stress-responsive signaling pathways induced by mitochondrial proteostasis perturbations. Molecular biology of the cell 35 (5) (2024)
Caroline Stanton, Jie Sun, Kayla Nutsch, Jessica D Rosarda, Thu Nguyen, Chloris Li-Ma, Evert Njomen, Bruno Melillo, Sergei Kutseikin, Enrique Saez, Benjamin F Cravatt, John R Teijaro, R Luke Wiseman, Michael J Bollong
Covalent Targeting As a Common Mechanism for Inhibiting NLRP3 Inflammasome Assembly. ACS chemical biology 19 (2) (2024)
Caroline Stanton, Jie Sun, Kayla Nutsch, Jessica D Rosarda, Thu Nguyen, Chloris Li-Ma, Evert Njomen, Bruno Melillo, Sergei Kutseikin, Enrique Saez, Benjamin F Cravatt, John R Teijaro, R Luke Wiseman, Michael J Bollong
Covalent Targeting As a Common Mechanism for Inhibiting NLRP3 Inflammasome Assembly. ACS chemical biology (2024)
Caroline Stanton, Jie Sun, Kayla Nutsch, Jessica D Rosarda, Thu Nguyen, Chloris Li-Ma, Evert Njomen, Bruno Melillo, Sergei Kutseikin, Enrique Saez, Benjamin F Cravatt, John R Teijaro, R Luke Wiseman, Michael J Bollong
Covalent Targeting As a Common Mechanism for Inhibiting NLRP3 Inflammasome Assembly. ACS chemical biology (2024)
Caroline Stanton, Jie Sun, Kayla Nutsch, Jessica D Rosarda, Thu Nguyen, Chloris Li-Ma, Evert Njomen, Bruno Melillo, Sergei Kutseikin, Enrique Saez, Benjamin F Cravatt, John R Teijaro, R Luke Wiseman, Michael J Bollong
Covalent Targeting As a Common Mechanism for Inhibiting NLRP3 Inflammasome Assembly. ACS chemical biology 19 (2) (2024)
Nicole Madrazo, Zinia Khattar, Evan T Powers, Jessica D Rosarda, R Luke Wiseman
Mapping Stress-Responsive Signaling Pathways Induced by Mitochondrial Proteostasis Perturbations. bioRxiv : the preprint server for biology (2024)
Caroline Stanton, Jie Sun, Kayla Nutsch, Jessica D Rosarda, Thu Nguyen, Chloris Li-Ma, Evert Njomen, Bruno Melillo, Sergei Kutseikin, Enrique Saez, Benjamin F Cravatt, John R Teijaro, R Luke Wiseman, Michael J Bollong
Covalent Targeting As a Common Mechanism for Inhibiting NLRP3 Inflammasome Assembly. ACS chemical biology 19 (2) (2024)
Kelsey R Baron, Samantha Oviedo, Sophia Krasny, Mashiat Zaman, Rama Aldakhlallah, Prakhyat Mathur, Gerald Pfeffer, Michael J Bollong, Timothy E Shutt, Danielle A Grotjahn, R Luke Wiseman
Pharmacologic Activation of Integrated Stress Response Kinases Inhibits Pathologic Mitochondrial Fragmentation. bioRxiv : the preprint server for biology (2024)
Caroline Stanton, Jie Sun, Kayla Nutsch, Jessica D Rosarda, Thu Nguyen, Chloris Li-Ma, Evert Njomen, Bruno Melillo, Sergei Kutseikin, Enrique Saez, Benjamin F Cravatt, John R Teijaro, R Luke Wiseman, Michael J Bollong
Covalent Targeting As a Common Mechanism for Inhibiting NLRP3 Inflammasome Assembly. ACS chemical biology 19 (2) (2024)
Nicole Madrazo, Zinia Khattar, Evan T Powers, Jessica D Rosarda, R Luke Wiseman
Mapping Stress-Responsive Signaling Pathways Induced by Mitochondrial Proteostasis Perturbations. bioRxiv : the preprint server for biology (2024)
Caroline Stanton, Chavin Buasakdi, Jie Sun, Ian Levitan, Prerona Bora, Sergei S Kutseikin, R Luke Wiseman, Michael J Bollong
The Glycolytic Metabolite Methylglyoxal Covalently Inactivates the NLRP3 Inflammasome. bioRxiv : the preprint server for biology (2024)
Nicole Madrazo, Zinia Khattar, Evan T Powers, Jessica D Rosarda, R Luke Wiseman
Mapping Stress-Responsive Signaling Pathways Induced by Mitochondrial Proteostasis Perturbations. bioRxiv : the preprint server for biology (2024)
Caroline Stanton, Chavin Buasakdi, Jie Sun, Ian Levitan, Prerona Bora, Sergei S Kutseikin, R Luke Wiseman, Michael J Bollong
The Glycolytic Metabolite Methylglyoxal Covalently Inactivates the NLRP3 Inflammasome. bioRxiv : the preprint server for biology (2024)
Nicole Madrazo, Zinia Khattar, Evan T Powers, Jessica D Rosarda, R Luke Wiseman
Mapping stress-responsive signaling pathways induced by mitochondrial proteostasis perturbations. Molecular biology of the cell 35 (5) (2024)
Nicole Madrazo, Zinia Khattar, Evan T Powers, Jessica D Rosarda, R Luke Wiseman
Mapping stress-responsive signaling pathways induced by mitochondrial proteostasis perturbations. Molecular biology of the cell 35 (5) (2024)
Nicole Madrazo, Zinia Khattar, Evan T Powers, Jessica D Rosarda, R Luke Wiseman
Mapping stress-responsive signaling pathways induced by mitochondrial proteostasis perturbations. Molecular biology of the cell 35 (5) (2024)
Caroline Stanton, Chavin Buasakdi, Jie Sun, Ian Levitan, Prerona Bora, Sergei S Kutseikin, R Luke Wiseman, Michael J Bollong
The Glycolytic Metabolite Methylglyoxal Covalently Inactivates the NLRP3 Inflammasome. bioRxiv : the preprint server for biology (2024)
Nicole Madrazo, Zinia Khattar, Evan T Powers, Jessica D Rosarda, R Luke Wiseman
Mapping stress-responsive signaling pathways induced by mitochondrial proteostasis perturbations. Molecular biology of the cell 35 (5) (2024)
Nicole Madrazo, Zinia Khattar, Evan T Powers, Jessica D Rosarda, R Luke Wiseman
Mapping Stress-Responsive Signaling Pathways Induced by Mitochondrial Proteostasis Perturbations. bioRxiv : the preprint server for biology (2024)
Caroline Stanton, Chavin Buasakdi, Jie Sun, Ian Levitan, Prerona Bora, Sergei S Kutseikin, R Luke Wiseman, Michael J Bollong
The Glycolytic Metabolite Methylglyoxal Covalently Inactivates the NLRP3 Inflammasome. bioRxiv : the preprint server for biology (2024)
Nicole Madrazo, Zinia Khattar, Evan T Powers, Jessica D Rosarda, R Luke Wiseman
Mapping Stress-Responsive Signaling Pathways Induced by Mitochondrial Proteostasis Perturbations. bioRxiv : the preprint server for biology (2024)
Benjamin A Barad, Michaela Medina, Daniel Fuentes, R Luke Wiseman, Danielle A Grotjahn
Quantifying organellar ultrastructure in cryo-electron tomography using a surface morphometrics pipeline. The Journal of cell biology 222 (4) (2023)
Jie Yang, Kelsey R Baron, Daniel E Pride, Anette Schneemann, Xiaoyan Guo, Wenqian Chen, Albert S Song, Giovanni Aviles, Martin Edward Kampmann, R Luke Wiseman, Gabriel C Lander
DELE1 oligomerization promotes integrated stress response activation. Nature structural & molecular biology (2023)
Benjamin A Barad, Michaela Medina, Daniel Fuentes, R Luke Wiseman, Danielle A Grotjahn
Quantifying organellar ultrastructure in cryo-electron tomography using a surface morphometrics pipeline. The Journal of cell biology 222 (4) (2023)
Benjamin A Barad, Michaela Medina, Daniel Fuentes, R Luke Wiseman, Danielle A Grotjahn
Quantifying organellar ultrastructure in cryo-electron tomography using a surface morphometrics pipeline. The Journal of cell biology 222 (4) (2023)
Lara Ibrahim, Caroline Stanton, Kayla Nutsch, Thu Nguyen, Chloris Li-Ma, Yeonjin Ko, Gabriel C Lander, R Luke Wiseman, Michael J Bollong
Succinylation of a KEAP1 sensor lysine promotes NRF2 activation. bioRxiv : the preprint server for biology (2023)
Yeonjin Ko, Mannkyu Hong, Seungbeom Lee, Manoj Kumar, Lara Ibrahim, Kayla Nutsch, Caroline Stanton, Phillip Sondermann, Braddock Sandoval, Maya L Bulos, Jonathan Iaconelli, Arnab K Chatterjee, R Luke Wiseman, Peter G Schultz, Michael J Bollong
S-lactoyl modification of KEAP1 by a reactive glycolytic metabolite activates NRF2 signaling. Proceedings of the National Academy of Sciences of the United States of America 120 (20) (2023)
Gabriel M Kline, Ryan J Paxman, Chung-Yon Lin, Nicole Madrazo, Julia M Grandjean, Kyunga Lee, Karina Nugroho, Evan T Powers, R Luke Wiseman, Jeffrey W Kelly
Divergent Proteome Reactivity Influences Arm-Selective Activation of Pharmacological Endoplasmic Reticulum Proteostasis Regulators. bioRxiv : the preprint server for biology (2023)
Gabriel M Kline, Ryan J Paxman, Chung-Yon Lin, Nicole Madrazo, Julia M Grandjean, Kyunga Lee, Karina Nugroho, Evan T Powers, R Luke Wiseman, Jeffrey W Kelly
Divergent Proteome Reactivity Influences Arm-Selective Activation of Pharmacological Endoplasmic Reticulum Proteostasis Regulators. bioRxiv : the preprint server for biology (2023)
Yeonjin Ko, Mannkyu Hong, Seungbeom Lee, Manoj Kumar, Lara Ibrahim, Kayla Nutsch, Caroline Stanton, Phillip Sondermann, Braddock Sandoval, Maya L Bulos, Jonathan Iaconelli, Arnab K Chatterjee, R Luke Wiseman, Peter G Schultz, Michael J Bollong
S-lactoyl modification of KEAP1 by a reactive glycolytic metabolite activates NRF2 signaling. Proceedings of the National Academy of Sciences of the United States of America 120 (20) (2023)
Valerie Perea, Christian Cole, Justine Lebeau, Vivian Dolina, Kelsey R Baron, Aparajita Madhavan, Jeffery W Kelly, Danielle A Grotjahn, R Luke Wiseman
PERK signaling promotes mitochondrial elongation by remodeling membrane phosphatidic acid. The EMBO journal (2023)
Valerie Perea, Kelsey R Baron, Vivian Dolina, Giovanni Aviles, Jessica D Rosarda, Xiaoyan Guo, Martin Edward Kampmann, R Luke Wiseman
Pharmacologic Activation of an Integrated Stress Response Kinase Promotes Mitochondrial Remodeling. bioRxiv : the preprint server for biology (2023)
Benjamin A Barad, Michaela Medina, Daniel Fuentes, R Luke Wiseman, Danielle A Grotjahn
Quantifying organellar ultrastructure in cryo-electron tomography using a surface morphometrics pipeline. The Journal of cell biology 222 (4) (2023)
Gabriel M Kline, Ryan J Paxman, Chung-Yon Lin, Nicole Madrazo, Leonard Yoon, Julia M D Grandjean, Kyunga Lee, Karina Nugroho, Evan T Powers, R Luke Wiseman, Jeffrey W Kelly
Divergent Proteome Reactivity Influences Arm-Selective Activation of the Unfolded Protein Response by Pharmacological Endoplasmic Reticulum Proteostasis Regulators. ACS chemical biology (2023)
Yeonjin Ko, Mannkyu Hong, Seungbeom Lee, Manoj Kumar, Lara Ibrahim, Kayla Nutsch, Caroline Stanton, Phillip Sondermann, Braddock Sandoval, Maya L Bulos, Jonathan Iaconelli, Arnab K Chatterjee, R Luke Wiseman, Peter G Schultz, Michael J Bollong
S-lactoyl modification of KEAP1 by a reactive glycolytic metabolite activates NRF2 signaling. Proceedings of the National Academy of Sciences of the United States of America 120 (20) (2023)
Yeonjin Ko, Mannkyu Hong, Seungbeom Lee, Manoj Kumar, Lara Ibrahim, Kayla Nutsch, Caroline Stanton, Phillip Sondermann, Braddock Sandoval, Maya L Bulos, Jonathan Iaconelli, Arnab K Chatterjee, R Luke Wiseman, Peter G Schultz, Michael J Bollong
S-lactoyl modification of KEAP1 by a reactive glycolytic metabolite activates NRF2 signaling. Proceedings of the National Academy of Sciences of the United States of America 120 (20) (2023)
Benjamin A Barad, Michaela Medina, Daniel Fuentes, R Luke Wiseman, Danielle A Grotjahn
Quantifying organellar ultrastructure in cryo-electron tomography using a surface morphometrics pipeline. The Journal of cell biology 222 (4) (2023)
Caroline Stanton, Jie Sun, Kayla Nutsch, Jessica D Rosarda, Thu Nguyen, Chloris Li-Ma, Sergei S Kutseikin, Enrique Saez, John R Teijaro, R Luke Wiseman, Michael J Bollong
Covalent targeting as a common mechanism for inhibiting NLRP3 inflammasome assembly. bioRxiv : the preprint server for biology (2023)
Yeonjin Ko, Mannkyu Hong, Seungbeom Lee, Manoj Kumar, Lara Ibrahim, Kayla Nutsch, Caroline Stanton, Phillip Sondermann, Braddock Sandoval, Maya L Bulos, Jonathan Iaconelli, Arnab K Chatterjee, R Luke Wiseman, Peter G Schultz, Michael J Bollong
S-lactoyl modification of KEAP1 by a reactive glycolytic metabolite activates NRF2 signaling. Proceedings of the National Academy of Sciences of the United States of America 120 (20) (2023)
Benjamin A Barad, Michaela Medina, Daniel Fuentes, R Luke Wiseman, Danielle A Grotjahn
Quantifying organellar ultrastructure in cryo-electron tomography using a surface morphometrics pipeline. The Journal of cell biology 222 (4) (2023)
Yeonjin Ko, Mannkyu Hong, Seungbeom Lee, Manoj Kumar, Lara Ibrahim, Kayla Nutsch, Caroline Stanton, Phillip Sondermann, Braddock Sandoval, Maya L Bulos, Jonathan Iaconelli, Arnab K Chatterjee, R Luke Wiseman, Peter G Schultz, Michael J Bollong
S-lactoyl modification of KEAP1 by a reactive glycolytic metabolite activates NRF2 signaling. Proceedings of the National Academy of Sciences of the United States of America 120 (20) (2023)
Benjamin A Barad, Michaela Medina, Daniel Fuentes, R Luke Wiseman, Danielle A Grotjahn
Quantifying organellar ultrastructure in cryo-electron tomography using a surface morphometrics pipeline. The Journal of cell biology 222 (4) (2023)
Jessica D Rosarda, Sarah Giles, Sarah Harkins-Perry, Elizabeth A Mills, Martin Friedlander, R Luke Wiseman, Kevin T Eade
Imbalanced unfolded protein response signaling contributes to 1-deoxysphingolipid retinal toxicity. Nature communications 14 (1) (2023)
Benjamin A Barad, Michaela Medina, Daniel Fuentes, R Luke Wiseman, Danielle A Grotjahn
Quantifying organellar ultrastructure in cryo-electron tomography using a surface morphometrics pipeline. The Journal of cell biology 222 (4) (2023)
Jaleh S Mesgarzadeh, Joel N Buxbaum, R Luke Wiseman
Stress-responsive regulation of extracellular proteostasis. The Journal of cell biology 221 (4) (2022)
Marie Pariollaud, Lara H Ibrahim, Emanuel Irizarry, Rebecca M Mello, Alanna B Chan, Brian J Altman, Reuben J Shaw, Michael J Bollong, R Luke Wiseman, Katja A Lamia
Circadian disruption enhances HSF1 signaling and tumorigenesis in Kras -driven lung cancer. Science advances 8 (39) (2022)
Vidyanath Chaudhary, Marie Dominique Ah Kioon, Sung-Min Hwang, Bikash Mishra, Kimberly S Lakin, Kyriakos A Kirou, Jeffrey Zhang-Sun, R Luke Wiseman, Robert F Spiera, Mary K Crow, Jessica K Gordon, Juan R Cubillos-Ruiz, Franck J Barrat
Chronic activation of pDCs in autoimmunity is linked to dysregulated ER stress and metabolic responses. The Journal of experimental medicine 219 (11) (2022)
Aparajita Madhavan, Bernard P Kok, Bibiana Rius, Julia M D Grandjean, Adekunle Alabi, Verena Albert, Ara Sukiasyan, Evan T Powers, Andrea Galmozzi, Enrique Saez, R Luke Wiseman
Pharmacologic IRE1/XBP1s activation promotes systemic adaptive remodeling in obesity. Nature communications 13 (1) (2022)
Jaleh S Mesgarzadeh, Isabelle C Romine, Ethan M Smith-Cohen, Julia M D Grandjean, Jeffery W Kelly, Joseph C Genereux, R Luke Wiseman
ATF6 Activation Reduces Amyloidogenic Transthyretin Secretion through Increased Interactions with Endoplasmic Reticulum Proteostasis Factors. Cells 11 (10) (2022)
Heike Kroeger, Julia M D Grandjean, Wei-Chieh Jerry Chiang, Daphne D Bindels, Rebecca Mastey, Jennifer Okalova, Amanda Nguyen, Evan T Powers, Jeffery W Kelly, Neil J Grimsey, Michel Michaelides, Joseph Carroll, R Luke Wiseman, Jonathan H Lin
ATF6 is essential for human cone photoreceptor development. Proceedings of the National Academy of Sciences of the United States of America 118 (39) (2021)
Jessica D Rosarda, Kelsey R Baron, Kayla Nutsch, Gabriel M Kline, Caroline Stanton, Jeffrey W Kelly, Michael J Bollong, R Luke Wiseman
Metabolically Activated Proteostasis Regulators Protect against Glutamate Toxicity by Activating NRF2. ACS chemical biology (2021)
Mia Shin, Edmond R Watson, Albert S Song, Jeffrey T Mindrebo, Scott J Novick, Patrick R Griffin, R Luke Wiseman, Gabriel C Lander
Structures of the human LONP1 protease reveal regulatory steps involved in protease activation. Nature communications 12 (1) (2021)
Oktay Kirak, Eugene Ke, Kevin Y Yang, Anna Schwarz, Lars Plate, Amy Nham, Justin R Abadejos, Anna Valencia, R Luke Wiseman, Kathy O Lui, Manching Ku
Premature Activation of Immune Transcription Programs in Autoimmune-Predisposed Mouse Embryonic Stem Cells and Blastocysts. International journal of molecular sciences 21 (16) (2020)
Lara Ibrahim, Jaleh Mesgarzadeh, Ian Xu, Evan T Powers, R Luke Wiseman, Michael J Bollong
Defining the Functional Targets of Cap'n'collar Transcription Factors NRF1, NRF2, and NRF3. Antioxidants (Basel, Switzerland) 9 (10) (2020)
Mia Shin, Cristina Puchades, Ananya Asmita, Neha Puri, Eric Adjei, R Luke Wiseman, A Wali Karzai, Gabriel C Lander
Structural basis for distinct operational modes and protease activation in AAA+ protease Lon. Science advances 6 (21) (2020)
Julia M D Grandjean, Aparajita Madhavan, Lauren Cech, Bryan O Seguinot, Ryan J Paxman, Emery Smith, Louis Scampavia, Evan T Powers, Christina B Cooley, Lars Plate, Timothy P Spicer, Jeffery W Kelly, R Luke Wiseman
Pharmacologic IRE1/XBP1s activation confers targeted ER proteostasis reprogramming. Nature chemical biology 16 (10) (2020)
Isabelle C Romine, R Luke Wiseman
PERK Signaling Regulates Extracellular Proteostasis of an Amyloidogenic Protein During Endoplasmic Reticulum Stress. Scientific reports 9 (1) (2019)
Erik A Blackwood, Khalid Azizi, Donna J Thuerauf, Ryan J Paxman, Lars Plate, Jeffery W Kelly, R Luke Wiseman, Christopher C Glembotski
Pharmacologic ATF6 activation confers global protection in widespread disease models by reprograming cellular proteostasis. Nature communications 10 (1) (2019)
Julia M D Grandjean, Lars Plate, Richard I Morimoto, Michael J Bollong, Evan T Powers, R Luke Wiseman
Deconvoluting Stress-Responsive Proteostasis Signaling Pathways for Pharmacologic Activation Using Targeted RNA Sequencing. ACS chemical biology 14 (4) (2019)
R Luke Wiseman
Lining up for quality control: linear ubiquitin and proteotoxicity. The EMBO journal 38 (9) (2019)
Amado Carreras-Sureda, Fabián Jaña, Hery Urra, Sylvere Durand, David E Mortenson, Alfredo Sagredo, Galdo Bustos, Younis Hazari, Eva Ramos-Fernández, Maria L Sassano, Philippe Pihán, Alexander R van Vliet, Matías González-Quiroz, Angie K Torres, Cheril Tapia-Rojas, Martijn Kerkhofs, Rubén Vicente, Alexandre Rosa Campos, Nibaldo C Inestrosa, Christian Gonzalez-Billault, R Luke Wiseman, Patrizia Agostinis, Geert Bultynck, Felipe A Court, Guido Kroemer, J César Cárdenas, Claudio Hetz
Non-canonical function of IRE1α determines mitochondria-associated endoplasmic reticulum composition to control calcium transfer and bioenergetics. Nature cell biology 21 (6) (2019)
Ryan J Paxman, Lars Plate, Erik A Blackwood, Chris Glembotski, Evan T Powers, R Luke Wiseman, Jeffrey W Kelly
Pharmacologic ATF6 activating compounds are metabolically activated to selectively modify endoplasmic reticulum proteins. eLife 7 (2018)
Cristina Puchades, Anthony J Rampello, Mia Shin, Christopher J Giuliano, R Luke Wiseman, Steven E Glynn, Gabriel C Lander
Structure of the mitochondrial inner membrane AAA+ protease YME1 gives insight into substrate processing. Science (New York, N.Y.) 358 (6363) (2018)
Heike Kroeger, Neil J Grimsey, Ryan J Paxman, Wei-Chieh Chiang, Lars Plate, Ying Jones, Peter X Shaw, JoAnn Trejo, Stephen H Tsang, Evan T Powers, Jeffrey W Kelly, R Luke Wiseman, Jonathan H Lin
The unfolded protein response regulator ATF6 promotes mesodermal differentiation. Science signaling 11 (517) (2018)
Kai-Chun Chen, Song Qu, Saikat Chowdhury, Isabelle C Noxon, Joseph D Schonhoft, Lars Plate, Evan T Powers, Jeffery W Kelly, Gabriel C Lander, R Luke Wiseman
The endoplasmic reticulum HSP40 co-chaperone ERdj3/DNAJB11 assembles and functions as a tetramer. The EMBO journal 36 (15) (2017)
Lars Plate, Ryan J Paxman, R Luke Wiseman, Jeffery W Kelly
Modulating protein quality control. eLife 5 (2016)
Lars Plate, Christina B Cooley, John J Chen, Ryan J Paxman, Ciara M Gallagher, Franck Madoux, Joseph C Genereux, Wesley Dobbs, Dan Garza, Timothy P Spicer, Louis Scampavia, Steven J Brown, Hugh Rosen, Evan T Powers, Peter Walter, Peter Hodder, R Luke Wiseman, Jeffery W Kelly
Small molecule proteostasis regulators that reprogram the ER to reduce extracellular protein aggregation. eLife 5 (2016)

R Luke Wiseman.css-eqlu8i{font-size:small;padding-left:4px;}

Publication Activity (10 Years)

Top Topics

Top Venues

R Luke Wiseman