Richard McCulloch

ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 20

Top Venues

University of Glasgow

University of Glasgow (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University of Glasgow Aug 01 2019

United Kingdom

Professor of Molecular and Cellular Parasitology :: Wellcome Centre for Integrative Parasitology

University of Glasgow Sep 01 2006 - Jul 31 2019

United Kingdom

Senior Lecturer - Reader :: Wellcome Centre for Molecular Parasitology

University of Glasgow Sep 01 1997 - Sep 01 2006

United Kingdom

Royal Society University Research Fellow :: Wellcome Trust Centre for Molecular Parasitology

Nederlands Kanker Instituut - Antoni van Leeuwenhoek Ziekenhuis Apr 01 1994 - Sep 01 1997

Netherlands

Wellcome Trust International fellow :: Division of Molecular Biology

University of Glasgow Mar 01 1993 - Apr 01 1994

United Kingdom

Post doc :: Genetics

Education History

University of Glasgow Oct 01 1989 - Mar 01 1993

United Kingdom

PHD :: Genetics

University of Glasgow Oct 01 1984 - Oct 01 1989

United Kingdom

BSC

Publications

João Luis Reis Cunha, Samuel A Pimenta-Carvalho, Laila V Almeida, Anderson C Dos Santos, Catarina A Marques, Jennifer A Black, Jeziel Dener Damasceno, Richard McCulloch, Daniella Castanheira Bartholomeu, Daniel Charlton Jeffares
Ancestral aneuploidy and stable chromosomal duplication resulting in differential genome structure and gene expression control in trypanosomatid parasites. Genome research (2024)
João Luis Reis Cunha, Samuel A Pimenta-Carvalho, Laila V Almeida, Anderson C Dos Santos, Catarina A Marques, Jennifer A Black, Jeziel Dener Damasceno, Richard McCulloch, Daniella Castanheira Bartholomeu, Daniel Charlton Jeffares
Ancestral aneuploidy and stable chromosomal duplication resulting in differential genome structure and gene expression control in trypanosomatid parasites. Genome research 34 (3) (2024)
João Luis Reis Cunha, Samuel A Pimenta-Carvalho, Laila V Almeida, Anderson C Dos Santos, Catarina A Marques, Jennifer A Black, Jeziel Dener Damasceno, Richard McCulloch, Daniella Castanheira Bartholomeu, Daniel Charlton Jeffares
Ancestral aneuploidy and stable chromosomal duplication resulting in differential genome structure and gene expression control in trypanosomatid parasites. Genome research 34 (3) (2024)
João Luis Reis Cunha, Samuel A Pimenta-Carvalho, Laila V Almeida, Anderson C Dos Santos, Catarina A Marques, Jennifer A Black, Jeziel Dener Damasceno, Richard McCulloch, Daniella Castanheira Bartholomeu, Daniel Charlton Jeffares
Ancestral aneuploidy and stable chromosomal duplication resulting in differential genome structure and gene expression control in trypanosomatid parasites. Genome research 34 (3) (2024)
João Luis Reis Cunha, Samuel A Pimenta-Carvalho, Laila V Almeida, Anderson C Dos Santos, Catarina A Marques, Jennifer A Black, Jeziel Dener Damasceno, Richard McCulloch, Daniella Castanheira Bartholomeu, Daniel Charlton Jeffares
Ancestral aneuploidy and stable chromosomal duplication resulting in differential genome structure and gene expression control in trypanosomatid parasites. Genome research 34 (3) (2024)
Mark J Girasol, Emma M Briggs, Catarina A Marques, José M Batista, Dario Beraldi, Richard Burchmore, Leandro Lemgruber, Richard McCulloch
Immunoprecipitation of RNA-DNA hybrid interacting proteins in Trypanosoma brucei reveals conserved and novel activities, including in the control of surface antigen expression needed for immune evasion by antigenic variation. Nucleic acids research (2023)
Jennifer A Black, Christen M Klinger, Leandro Lemgruber, Joel B Dacks, Jeremy C Mottram, Richard McCulloch
AAK1-like: A putative pseudokinase with potential roles in cargo uptake in bloodstream form Trypanosoma brucei parasites. The Journal of eukaryotic microbiology (2023)
Mark John Girasol, Marija Krasilnikova, Catarina A Marques, Jeziel Dener Damasceno, Craig Lapsley, Leandro Lemgruber, Richard J S Burchmore, Dario Beraldi, Ross Carruthers, Emma M Briggs, Richard McCulloch
RAD51-mediated R-loop formation acts to repair transcription-associated DNA breaks driving antigenic variation in Trypanosoma brucei . Proceedings of the National Academy of Sciences of the United States of America 120 (48) (2023)
Emma M Briggs, Federico Rojas, Richard McCulloch, Keith R Matthews, Thomas Dan Otto
Single-cell transcriptomic analysis of bloodstream Trypanosoma brucei reconstructs cell cycle progression and developmental quorum sensing. Nature communications 12 (1) (2021)
Jeremy C Mottram, Eric Fang, Xiaolei Ma, Elmarie Myburgh, Juliana B T Carnielli, Christopher Bower-Lepts, Elaine Brown, Ryan Ritchie, Suresh B Lakshminarayana, Yen-Liang Chen, Debjani Patra, Elizabeth Ornelas, Hazel X Y Koh, Sarah L Williams, Frantisek Supek, Daniel Paape, Richard McCulloch, Marcel Kaiser, Michael P Barrett, Jan Jiricek, Thierry T Diagana, Jeremy Charles Mottram, Srinivasa P S Rao
Targeting the trypanosome kinetochore with CLK1 protein kinase inhibitors. Nature microbiology 5 (10) (2020)
Jeziel Dener Damasceno, João Luis Reis Cunha, Kathryn Crouch, Dario Beraldi, Craig Lapsley, Luiz R O Tosi, Daniella Castanheira Bartholomeu, Richard McCulloch
Conditional knockout of RAD51-related genes in Leishmania major reveals a critical role for homologous recombination during genome replication. PLoS genetics 16 (7) (2020)
Jeziel Dener Damasceno, Catarina A Marques, Dario Beraldi, Kathryn Crouch, Craig Lapsley, Ricardo Obonaga, Luiz Ro Tosi, Richard McCulloch
Genome duplication in Leishmania major relies on persistent subtelomeric DNA replication. eLife 9 (2020)
Siddharth Jayaraman, Claire Harris, Edith Paxton, Anne-Marie Donachie, Heli Vaikkinen, Richard McCulloch, James P J Hall, John G Kenny, Luca Lenzi, Christiane Hertz-Fowler, Christina Cobbold, Richard Reeve, Tom Michoel, Liam J Morrison
Application of long read sequencing to determine expressed antigen diversity in Trypanosoma brucei infections. PLoS neglected tropical diseases 13 (4) (2019)
Marcelo Santos da Silva, Gustavo R Cayres-Silva, Marcela O Vitarelli, Paula A Marin, Priscila M Hiraiwa, Christiane B Araújo, Bruno B Scholl, Andrea R Ávila, Richard McCulloch, Marcelo da Silva Reis, Maria Carolina Elias
Transcription activity contributes to the firing of non-constitutive origins in African trypanosomes helping to maintain robustness in S-phase duration. Scientific reports 9 (1) (2019)
Marcelo Santos da Silva, Galadriel A Hovel-Miner, Emma M Briggs, Maria Carolina Elias, Richard McCulloch
Evaluation of mechanisms that may generate DNA lesions triggering antigenic variation in African trypanosomes. PLoS pathogens 14 (11) (2018)
Emma M Briggs, Kathryn Crouch, Leandro Lemgruber Soares, Craig Lapsley, Richard McCulloch
Ribonuclease H1-targeted R-loops in surface antigen gene expression sites can direct trypanosome immune evasion. PLoS genetics 14 (12) (2018)
Jennifer A Stortz, Tiago D Serafim, Sam Alsford, Jonathan M Wilkes, Fernando Fernández-Cortés, Graham Hamilton, Emma M Briggs, Leandro Lemgruber Soares, David Horn, Jeremy Charles Mottram, Richard McCulloch
Genome-wide and protein kinase-focused RNAi screens reveal conserved and novel damage response pathways in Trypanosoma brucei. PLoS pathogens 13 (7) (2017)
Fernando Fernández-Cortés, Tiago D Serafim, Jonathan M Wilkes, Nathaniel G Jones, Ryan Ritchie, Richard McCulloch, Jeremy Charles Mottram
RNAi screening identifies Trypanosoma brucei stress response protein kinases required for survival in the mouse. Scientific reports 7 (1) (2017)
Rebecca Devlin, Catarina A Marques, Richard McCulloch
Does DNA replication direct locus-specific recombination during host immune evasion by antigenic variation in the African trypanosome? Current genetics 63 (3) (2016)
Rebecca Devlin, Catarina A Marques, Daniel Paape, Marko Prorocic, Andrea C Zurita-Leal, Samantha J Campbell, Craig Lapsley, Nicholas Dickens, Richard McCulloch
Mapping replication dynamics in Trypanosoma brucei reveals a link with telomere transcription and antigenic variation. eLife 5 (2016)

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Publication Activity (10 Years)

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Richard McCulloch