Yen-Liang Chen (Yen Liang Chen)

Publication Activity (10 Years)

Years Active: 2020-2023
Publications (10 Years): 7

Top Topics

Electron Microscopy

Emergency Department

Top Venues

Science (New York, N.Y.)

Antimicrobial agents and chemotherapy

Journal of virology

Nature microbiology

This page only lists publications with an associated author ORCID identifier.

Publications

Srinivasa P S Rao, Matthew K Gould, Jonas Noeske, Jeremy C Mottram, Rajiv S Jumani, Pearly Shuyi Ng, Olivier René, Yen-Liang Chen, Marcel Kaiser, Ryan Ritchie, Amanda Fortes Francisco, Nila Johnson, Debjani Patra, Harry Cheung, Colin Deniston, Andreas D Schenk, Wilian A Cortopassi, Remo S Schmidt, Natalie Wiedemar, Bryanna Thomas, Rima Palkar, Nahdiyah A Ghafar, Vanessa Manoharan, Catherine Luu, Jonathan E Gable, Kah Fei Wan, Elmarie Myburgh, Jeremy Charles Mottram, S Whitney Barnes, John R Walker, Charles A Wartchow, Natasha Aziz, Colin Osborne, Juergen Wagner, Christopher Sarko, John M Kelly, Ujjini H Manjunatha, Pascal Mäser, Jan Jiricek, Suresh B Lakshminarayana, Michael P Barrett, Thierry Tidiane Diagana
Cyanotriazoles are selective topoisomerase II poisons that rapidly cure trypanosome infections. Science (New York, N.Y.) 380 (6652) (2023)
Srinivasa P S Rao, Matthew K Gould, Jonas Noeske, Jeremy C Mottram, Rajiv S Jumani, Pearly Shuyi Ng, Olivier René, Yen-Liang Chen, Marcel Kaiser, Ryan Ritchie, Amanda Fortes Francisco, Nila Johnson, Debjani Patra, Harry Cheung, Colin Deniston, Andreas D Schenk, Wilian A Cortopassi, Remo S Schmidt, Natalie Wiedemar, Bryanna Thomas, Rima Palkar, Nahdiyah A Ghafar, Vanessa Manoharan, Catherine Luu, Jonathan E Gable, Kah Fei Wan, Elmarie Myburgh, Jeremy Charles Mottram, S Whitney Barnes, John R Walker, Charles A Wartchow, Natasha Aziz, Colin Osborne, Juergen Wagner, Christopher Sarko, John M Kelly, Ujjini H Manjunatha, Pascal Mäser, Jan Jiricek, Suresh B Lakshminarayana, Michael P Barrett, Thierry Tidiane Diagana
Cyanotriazoles are selective topoisomerase II poisons that rapidly cure trypanosome infections. Science (New York, N.Y.) 380 (6652) (2023)
Srinivasa P S Rao, Matthew K Gould, Jonas Noeske, Jeremy C Mottram, Rajiv S Jumani, Pearly Shuyi Ng, Olivier René, Yen-Liang Chen, Marcel Kaiser, Ryan Ritchie, Amanda Fortes Francisco, Nila Johnson, Debjani Patra, Harry Cheung, Colin Deniston, Andreas D Schenk, Wilian A Cortopassi, Remo S Schmidt, Natalie Wiedemar, Bryanna Thomas, Rima Palkar, Nahdiyah A Ghafar, Vanessa Manoharan, Catherine Luu, Jonathan E Gable, Kah Fei Wan, Elmarie Myburgh, Jeremy Charles Mottram, S Whitney Barnes, John R Walker, Charles A Wartchow, Natasha Aziz, Colin Osborne, Juergen Wagner, Christopher Sarko, John M Kelly, Ujjini H Manjunatha, Pascal Mäser, Jan Jiricek, Suresh B Lakshminarayana, Michael P Barrett, Thierry Tidiane Diagana
Cyanotriazoles are selective topoisomerase II poisons that rapidly cure trypanosome infections. Science (New York, N.Y.) 380 (6652) (2023)
Stephanie A Moquin, Oliver Simon, Ratna Karuna, Suresh B Lakshminarayana, Fumiaki Yokokawa, Feng Wang, Chandra Saravanan, Jin Zhang, Craig W Day, Katherine Chan, Qing-Yin Wang, Siyan Lu, Hongping Dong, Kah Fei Wan, Siew Pheng Lim, Wei Liu, Cheah Chen Seh, Yen-Liang Chen, Haoying Xu, David T Barkan, Cyrille S Kounde, Wei Lin Sandra Sim, Gang Wang, Hui-Quan Yeo, Bin Zou, Wai Ling Chan, Mei Ding, Jae-Geun Song, Min Li, Colin Osborne, Francesca Blasco, Christopher Sarko, David Beer, Ghislain M C Bonamy, Vito G Sasseville, Pei-Yong Shi, Thierry Tidiane Diagana, Bryan K S Yeung, Feng Gu
NITD-688, a pan-serotype inhibitor of the dengue virus NS4B protein, shows favorable pharmacokinetics and efficacy in preclinical animal models. Science translational medicine 13 (579) (2021)
Jeremy C Mottram, Eric Fang, Xiaolei Ma, Elmarie Myburgh, Juliana B T Carnielli, Christopher Bower-Lepts, Elaine Brown, Ryan Ritchie, Suresh B Lakshminarayana, Yen-Liang Chen, Debjani Patra, Elizabeth Ornelas, Hazel X Y Koh, Sarah L Williams, Frantisek Supek, Daniel Paape, Richard McCulloch, Marcel Kaiser, Michael P Barrett, Jan Jiricek, Thierry T Diagana, Jeremy Charles Mottram, Srinivasa P S Rao
Targeting the trypanosome kinetochore with CLK1 protein kinase inhibitors. Nature microbiology 5 (10) (2020)
Ratna Karuna, Fumiaki Yokokawa, Keshi Wang, Jin Zhang, Haoying Xu, Gang Wang, Mei Ding, Wai Ling Chan, Nahdiyah Abdul Ghafar, Andrea Leonardi, Cheah Chen Seh, Peck Gee Seah, Wei Liu, Rao P S Srinivasa, Siew Pheng Lim, Suresh B Lakshminarayana, Ellie Growcott, Sreehari Babu, Martijn Fenaux, Weidong Zhong, Feng Gu, Pei-Yong Shi, Francesca Blasco, Yen-Liang Chen
A Cyclic Phosphoramidate Prodrug of 2'-Deoxy-2'-Fluoro-2'-C-Methylguanosine for the Treatment of Dengue Virus Infection. Antimicrobial agents and chemotherapy 64 (12) (2020)
Rishi Arora, Chong Wai Liew, Tingjin Sherryl Soh, Dorcas Adobea Otoo, Cheah Chen Seh, Kimberley Yue, Shahul Nilar, Gang Wang, Fumiaki Yokokawa, Christian G Noble, Yen-Liang Chen, Pei-Yong Shi, Julien Lescar, Thomas M Smith, Timothy E Benson, Siew Pheng Lim
Two RNA Tunnel Inhibitors Bind in Highly Conserved Sites in Dengue Virus NS5 Polymerase: Structural and Functional Studies. Journal of virology 94 (24) (2020)