Robert J Klose (Robert Klose, Rob Klose)

ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 34

Top Venues

Nature communications

eLife

bioRxiv : the preprint server for biology

Genome research

University of Oxford

University of Edinburgh (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University of Oxford Apr 01 2017

United Kingdom

Chair and Professor of Genetics :: Biochemistry

University of Oxford Feb 01 2013 - Apr 01 2017

United Kingdom

Wellcome Trust Senior Research Fellow :: Biochemistry

University of Oxford Feb 01 2008 - Feb 01 2013

United Kingdom

Wellcome Trust Research Career Development Fellow :: Biochemistry

University of North Carolina at Chapel Hill Jul 01 2005 - Sep 01 2007

United States

Post-doctoral Fellow :: Linberger Comprehensive Cancer Centre

Education History

University of Edinburgh Oct 01 2001 - May 01 2005

United Kingdom

PHD :: Wellcome Trust Centre for Cell Biology

University of Waterloo Sep 01 1996 - May 01 2001

Canada

BSC :: Biology

Publications

Allegra Angeloni, Skye D Fissette, Deniz U Kaya, Jillian M Hammond, Hasindu Gamaarachchi, Ira W Deveson, Robert J Klose, Weiming Li, Xiaotian Zhang, Ozren Bogdanovic
Extensive DNA methylome rearrangement during early lamprey embryogenesis. Nature communications 15 (1) (2024)
James M Gahan, Lily W Helfrich, Laura A Wetzel, Natarajan V Bhanu, Zuo-Fei Yuan, Benjamin A Garcia, Robert J Klose, David S Booth
Chromatin profiling identifies putative dual roles for H3K27me3 in regulating transposons and cell type-specific genes in choanoflagellates. bioRxiv : the preprint server for biology (2024)
Aleksander T Szczurek, Emilia Dimitrova, Jessica R Kelley, Neil P Blackledge, Robert J Klose
The Polycomb system sustains promoters in a deep OFF state by limiting pre-initiation complex formation to counteract transcription. Nature cell biology (2024)
James M Gahan, Lily W Helfrich, Laura A Wetzel, Natarajan V Bhanu, Zuo-Fei Yuan, Benjamin A Garcia, Robert J Klose, David S Booth
Chromatin profiling identifies putative dual roles for H3K27me3 in regulating transposons and cell type-specific genes in choanoflagellates. bioRxiv : the preprint server for biology (2024)
Allegra Angeloni, Skye D Fissette, Deniz U Kaya, Jillian M Hammond, Hasindu Gamaarachchi, Ira W Deveson, Robert J Klose, Weiming Li, Xiaotian Zhang, Ozren Bogdanovic
Extensive DNA methylome rearrangement during early lamprey embryogenesis. Nature communications 15 (1) (2024)
Allegra Angeloni, Skye D Fissette, Deniz U Kaya, Jillian M Hammond, Hasindu Gamaarachchi, Ira W Deveson, Robert J Klose, Weiming Li, Xiaotian Zhang, Ozren Bogdanovic
Extensive DNA methylome rearrangement during early lamprey embryogenesis. Nature communications 15 (1) (2024)
James M Gahan, Lily W Helfrich, Laura A Wetzel, Natarajan V Bhanu, Zuo-Fei Yuan, Benjamin A Garcia, Robert J Klose, David S Booth
Chromatin profiling identifies putative dual roles for H3K27me3 in regulating transposons and cell type-specific genes in choanoflagellates. bioRxiv : the preprint server for biology (2024)
James M Gahan, Lily W Helfrich, Laura A Wetzel, Natarajan V Bhanu, Zuo-Fei Yuan, Benjamin A Garcia, Robert J Klose, David S Booth
Chromatin profiling identifies putative dual roles for H3K27me3 in regulating transposons and cell type-specific genes in choanoflagellates. bioRxiv : the preprint server for biology (2024)
Helena G Asenjo, María Alcázar Fabra, Mencía Espinosa-Martínez, Lourdes Lopez-Onieva, Amador Gallardo, Emilia Dimitrova, Angelika Feldmann, Tomas Pachano, Jordi Martorell-Marugán, Pedro Carmona-Sáez, Antonio Sánchez Pozo, Álvaro Rada-Iglesias, Robert J Klose, David Landeira
Changes in PRC1 activity during interphase modulate lineage transition in pluripotent cells. Nature communications 14 (1) (2023)
Rinako Nakagawa, Miriam Llorian Sopena, Sunita Varsani-Brown, Probir Chakravarty, Jeannie M Camarillo, David J Barry, Roger George, Neil P Blackledge, Graham Duddy, Michael P Snyder, Robert J Klose, Martin Turner, Dinis Pedro Calado
MiR-155 epigenetically counteracts hypoxia for mitochondrial fitness during germinal center positive selection. bioRxiv : the preprint server for biology (2023)
Amy L Hughes, Aleksander T Szczurek, Jessica R Kelley, Anna Lastuvkova, Anne H Turberfield, Emilia Dimitrova, Neil P Blackledge, Robert J Klose
A CpG island-encoded mechanism protects genes from premature transcription termination. Nature communications 14 (1) (2023)
Helena G Asenjo, María Alcázar Fabra, Mencía Espinosa-Martínez, Lourdes Lopez-Onieva, Amador Gallardo, Emilia Dimitrova, Angelika Feldmann, Tomas Pachano, Jordi Martorell-Marugán, Pedro Carmona-Sáez, Antonio Sánchez Pozo, Álvaro Rada-Iglesias, Robert J Klose, David Landeira
Changes in PRC1 activity during interphase modulate lineage transition in pluripotent cells. Nature communications 14 (1) (2023)
Amy L Hughes, Aleksander T Szczurek, Jessica R Kelley, Anna Lastuvkova, Anne H Turberfield, Emilia Dimitrova, Neil P Blackledge, Robert J Klose
A CpG island-encoded mechanism protects genes from premature transcription termination. Nature communications 14 (1) (2023)
Helena G Asenjo, María Alcázar Fabra, Mencía Espinosa-Martínez, Lourdes Lopez-Onieva, Amador Gallardo, Emilia Dimitrova, Angelika Feldmann, Tomas Pachano, Jordi Martorell-Marugán, Pedro Carmona-Sáez, Antonio Sánchez Pozo, Álvaro Rada-Iglesias, Robert J Klose, David Landeira
Changes in PRC1 activity during interphase modulate lineage transition in pluripotent cells. Nature communications 14 (1) (2023)
Helena G Asenjo, María Alcázar Fabra, Mencía Espinosa-Martínez, Lourdes Lopez-Onieva, Amador Gallardo, Emilia Dimitrova, Angelika Feldmann, Tomas Pachano, Jordi Martorell-Marugán, Pedro Carmona-Sáez, Antonio Sánchez Pozo, Álvaro Rada-Iglesias, Robert J Klose, David Landeira
Changes in PRC1 activity during interphase modulate lineage transition in pluripotent cells. Nature communications 14 (1) (2023)
Amy L Hughes, Aleksander T Szczurek, Jessica R Kelley, Anna Lastuvkova, Anne H Turberfield, Emilia Dimitrova, Neil P Blackledge, Robert J Klose
A CpG island-encoded mechanism protects genes from premature transcription termination. Nature communications 14 (1) (2023)
Amy L Hughes, Aleksander T Szczurek, Jessica R Kelley, Anna Lastuvkova, Anne H Turberfield, Emilia Dimitrova, Neil P Blackledge, Robert J Klose
A CpG island-encoded mechanism protects genes from premature transcription termination. Nature communications 14 (1) (2023)
Helena G Asenjo, María Alcázar Fabra, Mencía Espinosa-Martínez, Lourdes Lopez-Onieva, Amador Gallardo, Emilia Dimitrova, Angelika Feldmann, Tomas Pachano, Jordi Martorell-Marugán, Pedro Carmona-Sáez, Antonio Sánchez Pozo, Álvaro Rada-Iglesias, Robert J Klose, David Landeira
Changes in PRC1 activity during interphase modulate lineage transition in pluripotent cells. Nature communications 14 (1) (2023)
Amy L Hughes, Aleksander T Szczurek, Jessica R Kelley, Anna Lastuvkova, Anne H Turberfield, Emilia Dimitrova, Neil P Blackledge, Robert J Klose
A CpG island-encoded mechanism protects genes from premature transcription termination. Nature communications 14 (1) (2023)
Amy L Hughes, Aleksander T Szczurek, Jessica R Kelley, Anna Lastuvkova, Anne H Turberfield, Emilia Dimitrova, Neil P Blackledge, Robert J Klose
A CpG island-encoded mechanism protects genes from premature transcription termination. Nature communications 14 (1) (2023)
Junichiro Takano, Shinsuke Ito, Yixing Dong, Jafar Sharif, Yaeko Nakajima-Takagi, Taichi Umeyama, Yong-Woon Han, Kyoichi Isono, Takashi Kondo, Yusuke Iizuka, Tomohiro Miyai, Yoko Koseki, Mika Ikegaya, Mizuki Sakihara, Manabu Nakayama, Osamu Ohara, Yoshinori Hasegawa, Kosuke Hashimoto, Erik Arner, Robert J Klose, Atsushi Iwama, Haruhiko Koseki, Tomokatsu Ikawa
PCGF1-PRC1 links chromatin repression with DNA replication during hematopoietic cell lineage commitment. Nature communications 13 (1) (2022)
Emilia Dimitrova, Angelika Feldmann, Robin H van der Weide, Koen D Flach, Anna Lastuvkova, Elzo de Wit, Robert J Klose
Distinct roles for CKM-Mediator in controlling Polycomb-dependent chromosomal interactions and priming genes for induction. Nature structural & molecular biology 29 (10) (2022)
Paula Dobrinić, Aleksander T Szczurek, Robert J Klose
PRC1 drives Polycomb-mediated gene repression by controlling transcription initiation and burst frequency. Nature structural & molecular biology 28 (10) (2021)
Neil P Blackledge, Robert J Klose
The molecular principles of gene regulation by Polycomb repressive complexes. Nature reviews. Molecular cell biology 22 (12) (2021)
Hiroki Sugishita, Takashi Kondo, Shinsuke Ito, Manabu Nakayama, Nayuta Yakushiji-Kaminatsui, Eiryo Kawakami, Yoko Koseki, Yasuhide Ohinata, Jafar Sharif, Mio Harachi, Neil P Blackledge, Robert J Klose, Haruhiko Koseki
Variant PCGF1-PRC1 links PRC2 recruitment with differentiation-associated transcriptional inactivation at target genes. Nature communications 12 (1) (2021)
Miles K Huseyin, Robert J Klose
Live-cell single particle tracking of PRC1 reveals a highly dynamic system with low target site occupancy. Nature communications 12 (1) (2021)
Martin Cusack, Hamish W King, Paolo Spingardi, Benedikt Mathias Kessler, Robert J Klose, Skirmantas Kriaucionis
Distinct contributions of DNA methylation and histone acetylation to the genomic occupancy of transcription factors. Genome research 30 (10) (2020)
Emilia Dimitrova, Takashi Kondo, Angelika Feldmann, Manabu Nakayama, Yoko Koseki, Rebecca Konietzny, Benedikt M Kessler, Haruhiko Koseki, Robert J Klose
FBXL19 recruits CDK-Mediator to CpG islands of developmental genes priming them for activation during lineage commitment. eLife 7 (2018)
Hamish W King, Nadezda A Fursova, Neil P Blackledge, Robert J Klose
Polycomb repressive complex 1 shapes the nucleosome landscape but not accessibility at target genes. Genome research 28 (10) (2018)
Mitsuhiro Endoh, Takaho A Endo, Jun Shinga, Katsuhiko Hayashi, Anca Farcas, Kit-Wan Ma, Shinsuke Ito, Jafar Sharif, Tamie Endoh, Naoko Onaga, Manabu Nakayama, Tomoyuki Ishikura, Osamu Masui, Benedikt M Kessler, Toshio Suda, Osamu Ohara, Akihiko Okuda, Robert J Klose, Haruhiko Koseki
PCGF6-PRC1 suppresses premature differentiation of mouse embryonic stem cells by regulating germ cell-related genes. eLife 6 (2017)
Hamish W King, Robert J Klose
The pioneer factor OCT4 requires the chromatin remodeller BRG1 to support gene regulatory element function in mouse embryonic stem cells. eLife 6 (2017)
Mitsuhiro Endoh, Takaho A Endo, Jun Shinga, Katsuhiko Hayashi, Anca Farcas, Kit-Wan Ma, Shinsuke Ito, Jafar Sharif, Tamie Endoh, Naoko Onaga, Manabu Nakayama, Tomoyuki Ishikura, Osamu Masui, Benedikt M Kessler, Toshio Suda, Osamu Ohara, Akihiko Okuda, Robert J Klose, Haruhiko Koseki
Correction: PCGF6-PRC1 suppresses premature differentiation of mouse embryonic stem cells by regulating germ cell-related genes. eLife 6 (2017)
Nathan R Rose, Hamish W King, Neil P Blackledge, Nadezda A Fursova, Katherine Ji Ember, Roman Fischer, Benedikt M Kessler, Robert J Klose
RYBP stimulates PRC1 to shape chromatin-based communication between Polycomb repressive complexes. eLife 5 (2016)
Christina Ernst, Jeremy Pike, Sarah J Aitken, Hannah K Long, Nils Eling, Lovorka Stojic, Michelle C Ward, Frances Connor, Timothy F Rayner, Margus Lukk, Robert J Klose, Claudia Kutter, Duncan T Odom
Successful transmission and transcriptional deployment of a human chromosome via mouse male meiosis. eLife 5 (2016)

Robert J Klose.css-eqlu8i{font-size:small;padding-left:4px;} (Robert Klose, Rob Klose)

Publication Activity (10 Years)

Top Topics

Top Venues

Robert J Klose (Robert Klose, Rob Klose)