Ruth H Palmer

Publication Activity (10 Years)

Years Active: 2015-2024
Publications (10 Years): 37

Top Topics

Advanced Non Small Cell Lung Cancer

Tyrosine Kinase

Top Venues

Proceedings of the National Academy of Sciences of the United States of America

Science signaling

This page only lists publications with an associated author ORCID identifier.

Publications

Jonatan L Gabre, Peter Merseburger, Arne Claeys, Joachim Tetteh Siaw, Sarah-Lee Bekaert, Frank Speleman, Bengt Hallberg, Ruth H Palmer, Jimmy Van den Eynden
Preclinical exploration of the DNA damage response pathway using the interactive neuroblastoma cell line explorer CLEAN. NAR cancer 6 (1) (2024)
Torben Ek, Raghda R Ibrahim, Hartmut Vogt, Kleopatra Georgantzi, Catarina Träger, Jennie Gaarder, Anna Djos, Ida Rahmqvist, Elisabeth Mellström, Fani Pujol-Calderón, Christoffer Vannas, Lina Hansson, Henrik Fagman, Diana Treis, Susanne Fransson, Tobias Österlund, Tzu-Po Chuang, Bronte Manouk Verhoeven, Anders Ståhlberg, Ruth H Palmer, Bengt Hallberg, Tommy Martinsson, Per Kogner, Martin G Dalin
Long-lasting response to lorlatinib in patients with ALK-driven relapsed or refractory neuroblastoma monitored with circulating tumor DNA analysis. Cancer research communications (2024)
Sanjay Kumar Sukumar, Vimala Anthonydhason, Linnea Molander, Jawdat Sandakly, Malak Kleit, Ganesh Umapathy, Patricia Mendoza-García, Tafheem Masudi, Andreas Schlosser, Dick R Nässel, Christian Wegener, Margret Shirinian, Ruth H Palmer
The Alk receptor tyrosine kinase regulates Sparkly, a novel activity regulating neuropeptide precursor in the Drosophila central nervous system. eLife 12 (2024)
Sanjay Kumar Sukumar, Vimala Anthonydhason, Linnea Molander, Jawdat Sandakly, Malak Kleit, Ganesh Umapathy, Patricia Mendoza-García, Tafheem Masudi, Andreas Schlosser, Dick R Nässel, Christian Wegener, Margret Shirinian, Ruth H Palmer
The Alk receptor tyrosine kinase regulates Sparkly, a novel activity regulating neuropeptide precursor in the Drosophila central nervous system. eLife 12 (2024)
Jonatan L Gabre, Peter Merseburger, Arne Claeys, Joachim Tetteh Siaw, Sarah-Lee Bekaert, Frank Speleman, Bengt Hallberg, Ruth H Palmer, Jimmy Van den Eynden
Preclinical exploration of the DNA damage response pathway using the interactive neuroblastoma cell line explorer CLEAN. NAR cancer 6 (1) (2024)
Sanjay Kumar Sukumar, Vimala Anthonydhason, Linnea Molander, Jawdat Sandakly, Malak Kleit, Ganesh Umapathy, Patricia Mendoza-García, Tafheem Masudi, Andreas Schlosser, Dick R Nässel, Christian Wegener, Margret Shirinian, Ruth H Palmer
The Alk receptor tyrosine kinase regulates Sparkly, a novel activity regulating neuropeptide precursor in the Drosophila central nervous system. eLife 12 (2024)
Sanjay Kumar Sukumar, Vimala Anthonydhason, Linnea Molander, Jawdat Sandakly, Malak Kleit, Ganesh Umapathy, Patricia Mendoza-García, Tafheem Masudi, Andreas Schlosser, Dick R Nässel, Christian Wegener, Margret Shirinian, Ruth H Palmer
The Alk receptor tyrosine kinase regulates Sparkly, a novel activity regulating neuropeptide precursor in the Drosophila central nervous system. eLife 12 (2024)
Sanjay Kumar Sukumar, Vimala Anthonydhason, Linnea Molander, Jawdat Sandakly, Malak Kleit, Ganesh Umapathy, Patricia Mendoza-García, Tafheem Masudi, Andreas Schlosser, Dick R Nässel, Christian Wegener, Margret Shirinian, Ruth H Palmer
The Alk receptor tyrosine kinase regulates Sparkly, a novel activity regulating neuropeptide precursor in the Drosophila central nervous system. eLife 12 (2024)
Marcus Borenäs, Ganesh Umapathy, Dan Emil Lind, Wei-Yun Lai, Jikui Guan, Joel Johansson, Eva Jennische, Alexander Schmidt, Yeshwant Kurhe, Jonatan L Gabre, Agata Aniszewska, Anneli Strömberg, Mats Bemark, Michael N Hall, Jimmy Van den Eynden, Bengt Hallberg, Ruth H Palmer
ALK signaling primes the DNA damage response sensitizing ALK-driven neuroblastoma to therapeutic ATR inhibition. Proceedings of the National Academy of Sciences of the United States of America 121 (1) (2023)
Tzu-Po Chuang, Wei-Yun Lai, Jonatan L Gabre, Dan E Lind, Ganesh Umapathy, Abdulmalik A Bokhari, Bengt Bergman, Linnea Kristenson, Fredrik B Thorén, Anh Le, Robert C Doebele, Jimmy Van den Eynden, Ruth H Palmer, Bengt Hallberg
ALK fusion NSCLC oncogenes promote survival and inhibit NK cell responses via SERPINB4 expression. Proceedings of the National Academy of Sciences of the United States of America 120 (8) (2023)
Tzu-Po Chuang, Wei-Yun Lai, Jonatan L Gabre, Dan E Lind, Ganesh Umapathy, Abdulmalik A Bokhari, Bengt Bergman, Linnea Kristenson, Fredrik B Thorén, Anh Le, Robert C Doebele, Jimmy Van den Eynden, Ruth H Palmer, Bengt Hallberg
ALK fusion NSCLC oncogenes promote survival and inhibit NK cell responses via SERPINB4 expression. Proceedings of the National Academy of Sciences of the United States of America 120 (8) (2023)
Tzu-Po Chuang, Wei-Yun Lai, Jonatan L Gabre, Dan E Lind, Ganesh Umapathy, Abdulmalik A Bokhari, Bengt Bergman, Linnea Kristenson, Fredrik B Thorén, Anh Le, Robert C Doebele, Jimmy Van den Eynden, Ruth H Palmer, Bengt Hallberg
ALK fusion NSCLC oncogenes promote survival and inhibit NK cell responses via SERPINB4 expression. Proceedings of the National Academy of Sciences of the United States of America 120 (8) (2023)
Marcus Borenäs, Ganesh Umapathy, Dan Emil Lind, Wei-Yun Lai, Jikui Guan, Joel Johansson, Eva Jennische, Alexander Schmidt, Yeshwant Kurhe, Jonatan L Gabre, Agata Aniszewska, Anneli Strömberg, Mats Bemark, Michael N Hall, Jimmy Van den Eynden, Bengt Hallberg, Ruth H Palmer
ALK signaling primes the DNA damage response sensitizing ALK-driven neuroblastoma to therapeutic ATR inhibition. Proceedings of the National Academy of Sciences of the United States of America 121 (1) (2023)
Tzu-Po Chuang, Wei-Yun Lai, Jonatan L Gabre, Dan E Lind, Ganesh Umapathy, Abdulmalik A Bokhari, Bengt Bergman, Linnea Kristenson, Fredrik B Thorén, Anh Le, Robert C Doebele, Jimmy Van den Eynden, Ruth H Palmer, Bengt Hallberg
ALK fusion NSCLC oncogenes promote survival and inhibit NK cell responses via SERPINB4 expression. Proceedings of the National Academy of Sciences of the United States of America 120 (8) (2023)
Marcus Borenäs, Ganesh Umapathy, Dan Emil Lind, Wei-Yun Lai, Jikui Guan, Joel Johansson, Eva Jennische, Alexander Schmidt, Yeshwant Kurhe, Jonatan L Gabre, Agata Aniszewska, Anneli Strömberg, Mats Bemark, Michael N Hall, Jimmy Van den Eynden, Bengt Hallberg, Ruth H Palmer
ALK signaling primes the DNA damage response sensitizing ALK-driven neuroblastoma to therapeutic ATR inhibition. Proceedings of the National Academy of Sciences of the United States of America 121 (1) (2023)
Tzu-Po Chuang, Wei-Yun Lai, Jonatan L Gabre, Dan E Lind, Ganesh Umapathy, Abdulmalik A Bokhari, Bengt Bergman, Linnea Kristenson, Fredrik B Thorén, Anh Le, Robert C Doebele, Jimmy Van den Eynden, Ruth H Palmer, Bengt Hallberg
ALK fusion NSCLC oncogenes promote survival and inhibit NK cell responses via SERPINB4 expression. Proceedings of the National Academy of Sciences of the United States of America 120 (8) (2023)
Tzu-Po Chuang, Wei-Yun Lai, Jonatan L Gabre, Dan E Lind, Ganesh Umapathy, Abdulmalik A Bokhari, Bengt Bergman, Linnea Kristenson, Fredrik B Thorén, Anh Le, Robert C Doebele, Jimmy Van den Eynden, Ruth H Palmer, Bengt Hallberg
ALK fusion NSCLC oncogenes promote survival and inhibit NK cell responses via SERPINB4 expression. Proceedings of the National Academy of Sciences of the United States of America 120 (8) (2023)
Jikui Guan, Marcus Borenäs, Junfeng Xiong, Wei-Yun Lai, Ruth H Palmer, Bengt Hallberg
IGF1R Contributes to Cell Proliferation in ALK -Mutated Neuroblastoma with Preference for Activating the PI3K-AKT Signaling Pathway. Cancers 15 (17) (2023)
Tzu-Po Chuang, Wei-Yun Lai, Jonatan L Gabre, Dan E Lind, Ganesh Umapathy, Abdulmalik A Bokhari, Bengt Bergman, Linnea Kristenson, Fredrik B Thorén, Anh Le, Robert C Doebele, Jimmy Van den Eynden, Ruth H Palmer, Bengt Hallberg
ALK fusion NSCLC oncogenes promote survival and inhibit NK cell responses via SERPINB4 expression. Proceedings of the National Academy of Sciences of the United States of America 120 (8) (2023)
Marcus Borenäs, Ganesh Umapathy, Dan Emil Lind, Wei-Yun Lai, Jikui Guan, Joel Johansson, Eva Jennische, Alexander Schmidt, Yeshwant Kurhe, Jonatan L Gabre, Agata Aniszewska, Anneli Strömberg, Mats Bemark, Michael N Hall, Jimmy Van den Eynden, Bengt Hallberg, Ruth H Palmer
ALK signaling primes the DNA damage response sensitizing ALK-driven neuroblastoma to therapeutic ATR inhibition. Proceedings of the National Academy of Sciences of the United States of America 121 (1) (2023)
Diana Treis, Ganesh Umapathy, Susanne Fransson, Jikui Guan, Patricia Mendoza-García, Joachim Tetteh Siaw, Sandra Wessman, Lena Gordon Murkes, Jakob J E Stenman, Anna Djos, Lotta H M Elfman, John Inge Johnsen, Bengt Hallberg, Ruth H Palmer, Tommy Martinsson, Per Kogner
Sustained Response to Entrectinib in an Infant With a Germline ALKAL2 Variant and Refractory Metastatic Neuroblastoma With Chromosomal 2p Gain and Anaplastic Lymphoma Kinase and Tropomyosin Receptor Kinase Activation. JCO precision oncology 6 (2022)
Kathrin Pfeifer, Georg Wolfstetter, Vimala Anthonydhason, Tafheem Masudi, Badrul Arefin, Mats Bemark, Patricia Mendoza-García, Ruth H Palmer
Patient-associated mutations in Drosophila Alk perturb neuronal differentiation and promote survival. Disease models & mechanisms 15 (8) (2022)
Joanna Szydzik, Dan Emil Lind, Badrul Arefin, Yeshwant Kurhe, Ganesh Umapathy, Joachim Tetteh Siaw, Arne Claeys, Jonatan L Gabre, Jimmy Van den Eynden, Bengt Hallberg, Ruth H Palmer
ATR inhibition enables complete tumour regression in ALK-driven NB mouse models. Nature communications 12 (1) (2021)
Jikui Guan, Bengt Hallberg, Ruth H Palmer
Chromosome Imbalances in Neuroblastoma-Recent Molecular Insight into Chromosome 1p-deletion, 2p-gain, and 11q-deletion Identifies New Friends and Foes for the Future. Cancers 13 (23) (2021)
Marcus Borenäs, Ganesh Umapathy, Wei-Yun Lai, Dan Emil Lind, Barbara Witek, Jikui Guan, Patricia Mendoza-García, Tafheem Masudi, Arne Claeys, Tzu-Po Chuang, Abeer El Wakil, Badrul Arefin, Susanne Fransson, Jan Koster, Mathias Johansson, Jennie Gaarder, Jimmy Van den Eynden, Bengt Hallberg, Ruth H Palmer
ALK ligand ALKAL2 potentiates MYCN-driven neuroblastoma in the absence of ALK mutation. The EMBO journal 40 (3) (2021)
Joachim T Siaw, Jonatan L Gabre, Ezgi Uçkun, Marc Vigny, Wancun Zhang, Jimmy Van den Eynden, Bengt Hallberg, Ruth H Palmer, Jikui Guan
Loss of RET Promotes Mesenchymal Identity in Neuroblastoma Cells. Cancers 13 (8) (2021)
Patricia Mendoza-García, Swaraj Basu, Sanjay Kumar Sukumar, Badrul Arefin, Georg Wolfstetter, Vimala Anthonydhason, Linnea Molander, Ezgi Uçkun, Henrik Lindehell, Cristina Lebrero-Fernandez, Jan Larsson, Erik Larsson, Mats Bemark, Ruth H Palmer
DamID transcriptional profiling identifies the Snail/Scratch transcription factor Kahuli as an Alk target in the Drosophila visceral mesoderm. Development (Cambridge, England) 148 (23) (2021)
Georg Wolfstetter, Kathrin Pfeifer, Mattias Backman, Tafheem A Masudi, Patricia Mendoza-García, Sa Chen, Hannah Sonnenberg, Sanjay K Sukumar, Ezgi Uçkun, Guarav K Varshney, Anne Uv, Ruth H Palmer
Identification of the Wallenda JNKKK as an Alk suppressor reveals increased competitiveness of Alk-expressing cells. Scientific reports 10 (1) (2020)
Niloufar Javanmardi, Susanne Fransson, Anna Djos, Ganesh Umapathy, Malin Östensson, Jelena Milosevic, Marcus Borenäs, Bengt Hallberg, Per Kogner, Tommy Martinsson, Ruth H Palmer
Analysis of ALK, MYCN, and the ALK ligand ALKAL2 (FAM150B/AUGα) in neuroblastoma patient samples with chromosome arm 2p rearrangements. Genes, chromosomes & cancer (2019)
Georg Wolfstetter, Ina Dahlitz, Kathrin Pfeifer, Uwe Töpfer, Joscha Arne Alt, Daniel Christoph Pfeifer, Reinhard Lakes-Harlan, Stefan Baumgartner, Ruth H Palmer, Anne Holz
Characterization of Drosophila Nidogen/entactin reveals roles in basement membrane stability, barrier function and nervous system patterning. Development (Cambridge, England) 146 (2) (2019)
Andrey Fadeev, Patricia Mendoza-Garcia, Uwe Irion, Jikui Guan, Kathrin Pfeifer, Stephanie Wiessner, Fabrizio Serluca, Ajeet Pratap Singh, Christiane Nüsslein-Volhard, Ruth H Palmer
ALKALs are in vivo ligands for ALK family receptor tyrosine kinases in the neural crest and derived cells. Proceedings of the National Academy of Sciences of the United States of America 115 (4) (2018)
Martin Dahl-Halvarsson, Montse Olive, Malgorzata Pokrzywa, Katarina Ejeskär, Ruth H Palmer, Anne Elisabeth Uv, Homa Tajsharghi
Drosophila model of myosin myopathy rescued by overexpression of a TRIM-protein family member. Proceedings of the National Academy of Sciences of the United States of America 115 (28) (2018)
Jimmy Van den Eynden, Ganesh Umapathy, Arghavan Ashouri, Diana Cervantes-Madrid, Joanna Szydzik, Kristina Ruuth, Jan Koster, Erik Larsson, Jikui Guan, Ruth H Palmer, Bengt Hallberg
Phosphoproteome and gene expression profiling of ALK inhibition in neuroblastoma cell lines reveals conserved oncogenic pathways. Science signaling 11 (557) (2018)
Jikui Guan, Susanne Fransson, Joachim Tetteh Siaw, Diana Treis, Jimmy Van den Eynden, Damini Chand, Ganesh Umapathy, Kristina Ruuth, Petter Svenberg, Sandra Wessman, Alia Shamikh, Hans Jacobsson, Lena Gordon, Jakob Stenman, Pär-Johan Svensson, Magnus Hansson, Erik Larsson, Tommy Martinsson, Ruth H Palmer, Per Kogner, Bengt Hallberg
Clinical response of the novel activating ALK-I1171T mutation in neuroblastoma to the ALK inhibitor ceritinib. Cold Spring Harbor molecular case studies 4 (4) (2018)
Georg Wolfstetter, Kathrin Pfeifer, Jesper R van Dijk, Fredrik Hugosson, Xiangyi Lu, Ruth H Palmer
The scaffolding protein Cnk binds to the receptor tyrosine kinase Alk to promote visceral founder cell specification in Drosophila. Science signaling 10 (502) (2017)
Patricia Mendoza-García, Fredrik Hugosson, Mahsa Fallah, Michael L Higgins, Yasuno Iwasaki, Kathrin Pfeifer, Georg Wolfstetter, Guarav K Varshney, Dmitry Popichenko, John Peter Gergen, Korneel Hens, Bart Deplancke, Ruth H Palmer
The Zic family homologue Odd-paired regulates Alk expression in Drosophila. PLoS genetics 13 (4) (2017)
Ganesh Umapathy, Jikui Guan, Dan Emil Lind, Niloufar Javanmardi, Diana Cervantes-Madrid, Anna Djos, Tommy Martinsson, Ruth H Palmer, Bengt Hallberg
MEK inhibitor trametinib does not prevent the growth of anaplastic lymphoma kinase (ALK)-addicted neuroblastomas. Science signaling 10 (507) (2017)
Jikui Guan, Ganesh Umapathy, Yasuo Yamazaki, Georg Wolfstetter, Patricia Mendoza, Kathrin Pfeifer, Ateequrrahman Mohammed, Fredrik Hugosson, Hongbing Zhang, Amy W Hsu, Robert Halenbeck, Bengt Hallberg, Ruth H Palmer
FAM150A and FAM150B are activating ligands for anaplastic lymphoma kinase. eLife 4 (2015)