Frank Speleman (F Speleman)

Publication Activity (10 Years)

Years Active: 2015-2024
Publications (10 Years): 20

Top Topics

Embryonic Stem Cells

Transcription Factor

Dna Damage Response

Top Venues

Nature communications

Scientific reports

This page only lists publications with an associated author ORCID identifier.

Publications

Jonatan L Gabre, Peter Merseburger, Arne Claeys, Joachim Tetteh Siaw, Sarah-Lee Bekaert, Frank Speleman, Bengt Hallberg, Ruth H Palmer, Jimmy Van den Eynden
Preclinical exploration of the DNA damage response pathway using the interactive neuroblastoma cell line explorer CLEAN. NAR cancer 6 (1) (2024)
Jonatan L Gabre, Peter Merseburger, Arne Claeys, Joachim Tetteh Siaw, Sarah-Lee Bekaert, Frank Speleman, Bengt Hallberg, Ruth H Palmer, Jimmy Van den Eynden
Preclinical exploration of the DNA damage response pathway using the interactive neuroblastoma cell line explorer CLEAN. NAR cancer 6 (1) (2024)
Alice Salib, Nisitha Jayatilleke, Janith A Seneviratne, Chelsea Mayoh, Katleen De Preter, Frank Speleman, Belamy B Cheung, Daniel R Carter, Glenn M Marshall
MYCN and SNRPD3 cooperate to maintain a balance of alternative splicing events that drives neuroblastoma progression. Oncogene (2023)
Bieke Decaesteker, Amber Louwaige, Siebe Loontiens, Fanny De Vloed, Sarah-Lee Bekaert, Juliette Roels, Suzanne Vanhauwaert, Sara De Brouwer, Ellen Sanders, Alla Berezovskaya, Geertrui Denecker, Eva D'haene, Stéphane Van Haver, Wouter Van Loocke, Jo Van Dorpe, David Creytens, Nadine Van Roy, Tim Pieters, Christophe Van Neste, Matthias Fischer, Pieter Van Vlierberghe, Stephen S Roberts, Johannes Hubertus Schulte, Sara Ek, Rogier Versteeg, Jan Koster, Johan van Nes, Mark W Zimmerman, Katleen De Preter, Frank Speleman
SOX11 regulates SWI/SNF complex components as member of the adrenergic neuroblastoma core regulatory circuitry. Nature communications 14 (1) (2023)
Bieke Decaesteker, Amber Louwaige, Siebe Loontiens, Fanny De Vloed, Sarah-Lee Bekaert, Juliette Roels, Suzanne Vanhauwaert, Sara De Brouwer, Ellen Sanders, Alla Berezovskaya, Geertrui Denecker, Eva D'haene, Stéphane Van Haver, Wouter Van Loocke, Jo Van Dorpe, David Creytens, Nadine Van Roy, Tim Pieters, Christophe Van Neste, Matthias Fischer, Pieter Van Vlierberghe, Stephen S Roberts, Johannes Hubertus Schulte, Sara Ek, Rogier Versteeg, Jan Koster, Johan van Nes, Mark W Zimmerman, Katleen De Preter, Frank Speleman
SOX11 regulates SWI/SNF complex components as member of the adrenergic neuroblastoma core regulatory circuitry. Nature communications 14 (1) (2023)
Bieke Decaesteker, Amber Louwaige, Siebe Loontiens, Fanny De Vloed, Sarah-Lee Bekaert, Juliette Roels, Suzanne Vanhauwaert, Sara De Brouwer, Ellen Sanders, Alla Berezovskaya, Geertrui Denecker, Eva D'haene, Stéphane Van Haver, Wouter Van Loocke, Jo Van Dorpe, David Creytens, Nadine Van Roy, Tim Pieters, Christophe Van Neste, Matthias Fischer, Pieter Van Vlierberghe, Stephen S Roberts, Johannes Hubertus Schulte, Sara Ek, Rogier Versteeg, Jan Koster, Johan van Nes, Mark W Zimmerman, Katleen De Preter, Frank Speleman
SOX11 regulates SWI/SNF complex components as member of the adrenergic neuroblastoma core regulatory circuitry. Nature communications 14 (1) (2023)
Lei Zhai, Anushree Balachandran, Rebecca Larkin, Janith A Seneviratne, Sylvia A Chung, Amit Lalwani, Shoma Tsubota, Dominik Beck, Kenji Kadomatsu, Anneleen Beckers, Kaat Durink, Katleen De Preter, Frank Speleman, Michelle Haber, Murray D Norris, Alexander Swarbrick, Belamy B Cheung, Glenn M Marshall, Daniel R Carter
Mitotic Dysregulation at Tumor Initiation Creates a Therapeutic Vulnerability to Combination Anti-Mitotic and Pro-Apoptotic Agents for MYCN-Driven Neuroblastoma. International journal of molecular sciences 24 (21) (2023)
Sofia Zanotti, Bieke Decaesteker, Suzanne Vanhauwaert, Bram De Wilde, Winnok H De Vos, Frank Speleman
Cellular senescence in neuroblastoma. British journal of cancer 126 (11) (2022)
Jolien De Wyn, Mark W Zimmerman, Nina Weichert-Leahey, Carolina Nunes, Belamy B Cheung, Brian J Abraham, Anneleen Beckers, Pieter-Jan Volders, Bieke Decaesteker, Daniel R Carter, Alfred Thomas Look, Katleen De Preter, Wouter Van Loocke, Glenn M Marshall, Adam D Durbin, Frank Speleman, Kaat Durink
MEIS2 Is an Adrenergic Core Regulatory Transcription Factor Involved in Early Initiation of TH-MYCN-Driven Neuroblastoma Formation. Cancers 13 (19) (2021)
Bieke Decaesteker, Kaat Durink, Nadine Van Roy, Bram De Wilde, Christophe Van Neste, Stéphane Van Haver, Stephen S Roberts, Katleen De Preter, Vermeirssen Vanessa, Frank Speleman
From DNA Copy Number Gains and Tumor Dependencies to Novel Therapeutic Targets for High-Risk Neuroblastoma. Journal of personalized medicine 11 (12) (2021)
Siebe Loontiens, Suzanne Vanhauwaert, Lisa Depestel, Givani Dewyn, Wouter Van Loocke, Finola E Moore, Elaine G Garcia, Lance Batchelor, Chiara Borga, Barbara Squiban, Megan Malone-Perez, Pieter-Jan Volders, Volodimir Olexiouk, Pieter Van Vlierberghe, David M Langenau, J Kimble Frazer, Kaat Durink, Frank Speleman
A novel TLX1-driven T-ALL zebrafish model: comparative genomic analysis with other leukemia models. Leukemia 34 (12) (2020)
E G Garcia, Alexandra Veloso, M L Oliveira, James R Allen, Siebe Loontiens, D Brunson, D Do, Chuan Yan, R Morris, S Iyer, Sara P Garcia, N Iftimia, W Van Loocke, F Matthijssens, K McCarthy, Joao T Barata, Frank Speleman, Tom Taghon, Alejandro Gutierrez, Pieter Van Vlierberghe, W Haas, J S Blackburn, David M Langenau
PRL3 enhances T-cell acute lymphoblastic leukemia growth through suppressing T-cell signaling pathways and apoptosis. Leukemia 35 (3) (2020)
Liselot M Mus, Irina Lambertz, Shana Claeys, Candy Kumps, Wouter Van Loocke, Christophe Van Neste, Ganesh Umapathy, Marica Vaapil, Christoph Bartenhagen, Genevieve Laureys, Olivier De Wever, Daniel Bexell, Matthias Fischer, Bengt Hallberg, Johannes Schulte, Bram De Wilde, Kaat Durinck, Geertrui Denecker, Katleen De Preter, Frank Speleman
The ETS transcription factor ETV5 is a target of activated ALK in neuroblastoma contributing to increased tumour aggressiveness. Scientific reports 10 (1) (2020)
Suzanne Vanhauwaert, Bieke Decaesteker, Sara De Brouwer, Carina Leonelli, Kaat Durinck, Pieter Mestdagh, Jo Vandesompele, Karen Sermon, Geertrui Denecker, Christophe Van Neste, Frank Speleman, Katleen De Preter
Publisher Correction: In silico discovery of a FOXM1 driven embryonal signaling pathway in therapy resistant neuroblastoma tumors. Scientific reports 9 (1) (2019)
Bieke Decaesteker, Katleen De Preter, Frank Speleman
DREAM target reactivation by core transcriptional regulators supports neuroblastoma growth. Molecular & cellular oncology 6 (2) (2019)
Lucía Lorenzi, Francisco Avila Cobos, Anneleen Decock, Celine Everaert, Hetty Hilde Helsmoortel, Steve Lefever, Karen Verboom, Pieter-Jan Volders, Frank Speleman, Jo Vandesompele, Pieter Mestdagh
Long noncoding RNA expression profiling in cancer: Challenges and opportunities. Genes, chromosomes & cancer 58 (4) (2019)
Shana Claeys, Geertrui Denecker, Kaat Durinck, Bieke Decaesteker, Liselot M Mus, Siebe Loontiens, Suzanne Vanhauwaert, Kristina Althoff, Caroline Wigerup, Daniel Bexell, Emmy Dolman, Kai-Oliver Henrich, Lea Wehrmann, Ellen M Westerhout, Jean-Baptiste Demoulin, Candy Kumps, Tom Van Maerken, Genevieve Laureys, Christophe Van Neste, Bram De Wilde, Olivier De Wever, Frank Westermann, Rogier Versteeg, Jan J Molenaar, Sven Påhlman, Johannes H Schulte, Katleen De Preter, Frank Speleman
ALK positively regulates MYCN activity through repression of HBP1 expression. Oncogene 38 (15) (2018)
Bieke Decaesteker, Geertrui Denecker, Christophe Van Neste, Emmy M Dolman, Wouter Van Loocke, Moritz Gartlgruber, Carolina Nunes, Fanny De Vloed, Pauline Depuydt, Karen Verboom, Dries Rombaut, Siebe Loontiens, Jolien De Wyn, Waleed M Kholosy, Bianca Koopmans, Anke H W Essing, Carl Herrmann, Daniel Dreidax, Kaat Durinck, Dieter Deforce, Filip Van Nieuwerburgh, Anton G Henssen, Rogier Versteeg, Valentina Boeva, Gudrun Schleiermacher, Johan van Nes, Pieter Mestdagh, Suzanne Vanhauwaert, Johannes H Schulte, Frank Westermann, Jan J Molenaar, Katleen De Preter, Frank Speleman
TBX2 is a neuroblastoma core regulatory circuitry component enhancing MYCN/FOXM1 reactivation of DREAM targets. Nature communications 9 (1) (2018)
Suzanne Vanhauwaert, Bieke Decaesteker, Sara De Brouwer, Carina Leonelli, Kaat Durinck, Pieter Mestdagh, Jo Vandesompele, Karen Sermon, Geertrui Denecker, Christophe Van Neste, Frank Speleman, Katleen De Preter
In silico discovery of a FOXM1 driven embryonal signaling pathway in therapy resistant neuroblastoma tumors. Scientific reports 8 (1) (2018)
Pauline Depuydt, Jan Koster, Valentina Boeva, Toby D Hocking, Frank Speleman, Gudrun Schleiermacher
Meta-mining of copy number profiles of high-risk neuroblastoma tumors. Scientific data 5 (2018)
Hetty Hilde Helsmoortel, Silvia Bresolin, Tim Lammens, Hélène Cavé, Peter Noellke, Aurélie Caye, Farzaneh Ghazavi, Andrica de Vries, Henrik Hasle, Veerle Labarque, Riccardo Masetti, Jan Stary, Marry M M van den Heuvel-Eibrink, Jan Philippé, Nadine Van Roy, Yves Benoit, Frank Speleman, Charlotte Niemeyer, Christian Flotho, Giuseppe Basso, Geertruy Te Kronnie, Pieter Van Vlierberghe, Barbara De Moerloose
LIN28B overexpression defines a novel fetal-like subgroup of juvenile myelomonocytic leukemia. Blood 127 (9) (2015)