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Sabine Ehrt

ORCID

Publication Activity (10 Years)

Years Active: 2016-2023
Publications (10 Years): 22

Top Venues

eLife

Nature communications

mBio

Proceedings of the National Academy of Sciences of the United States of America

Weill Cornell Medical College

Friedrich-Alexander-Universität Erlangen-Nürnberg (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Weill Cornell Medical College Oct 1o 1999

United States

Professor :: Microbiology and Immunology

Education History

Friedrich-Alexander-Universität Erlangen-Nürnberg Sep 1o 1989 - May 1o 1994

Germany

PHD :: Microbiology

Publications

Ritu Sharma, Travis E Hartman, Tiago Beites, Jee-Hyun Kim, Hyungjin Eoh, Curtis A Engelhart, Linnan Zhu, Daniel J Wilson, Courtney C Aldrich, Sabine Ehrt, Kyu Young Rhee, Dirk Schnappinger
Metabolically distinct roles of NAD synthetase and NAD kinase define the essentiality of NAD and NADP in Mycobacterium tuberculosis . mBio (2023)
Andrew I Wong, Tiago Beites, Kyle A Planck, Rachael A Fieweger, Kathryn A Eckartt, Shuqi Li, Nicholas C Poulton, Brian C VanderVen, Kyu Y Rhee, Dirk Schnappinger, Sabine Ehrt, Jeremy M Rock
Cyclic AMP is a critical mediator of intrinsic drug resistance and fatty acid metabolism in M. tuberculosis . eLife 12 (2023)
Andrew I Wong, Tiago Beites, Kyle A Planck, Rachael A Fieweger, Kathryn A Eckartt, Shuqi Li, Nicholas C Poulton, Brian C VanderVen, Kyu Y Rhee, Dirk Schnappinger, Sabine Ehrt, Jeremy M Rock
Cyclic AMP is a critical mediator of intrinsic drug resistance and fatty acid metabolism in M. tuberculosis . eLife 12 (2023)
Andrew I Wong, Tiago Beites, Kyle A Planck, Rachael A Fieweger, Kathryn A Eckartt, Shuqi Li, Nicholas C Poulton, Brian C VanderVen, Kyu Y Rhee, Dirk Schnappinger, Sabine Ehrt, Jeremy M Rock
Cyclic AMP is a critical mediator of intrinsic drug resistance and fatty acid metabolism in M. tuberculosis . eLife 12 (2023)
Andrew I Wong, Tiago Beites, Kyle A Planck, Rachael A Fieweger, Kathryn A Eckartt, Shuqi Li, Nicholas C Poulton, Brian C VanderVen, Kyu Y Rhee, Dirk Schnappinger, Sabine Ehrt, Jeremy M Rock
Cyclic AMP is a critical mediator of intrinsic drug resistance and fatty acid metabolism in M. tuberculosis . eLife 12 (2023)
Andrew I Wong, Tiago Beites, Kyle A Planck, Rachael A Fieweger, Kathryn A Eckartt, Shuqi Li, Nicholas C Poulton, Brian C VanderVen, Kyu Y Rhee, Dirk Schnappinger, Sabine Ehrt, Jeremy M Rock
Cyclic AMP is a critical mediator of intrinsic drug resistance and fatty acid metabolism in M. tuberculosis . eLife 12 (2023)
Yuanyuan Xu, Sabine Ehrt, Dirk Schnappinger, Tiago Beites
Synthetic lethality of Mycobacterium tuberculosis NADH dehydrogenases is due to impaired NADH oxidation. mBio (2023)
Eun-Ik Koh, Peter O Oluoch, Nadine Ruecker, Megan K Proulx, Vijay Soni, Kenan C Murphy, Kadamba Papavinasasundaram, Charlotte J Reames, Carolina Trujillo, Anisha Zaveri, Matthew D Zimmerman, Roshanak Aslebagh, Richard E Baker, Scott A Shaffer, Kristine M Guinn, Michael Fitzgerald, Veronique Anne Dartois, Sabine Ehrt, Deborah T Hung, Thomas R Ioerger, Eric J Rubin, Kyu Y Rhee, Dirk Schnappinger, Christopher M Sassetti
Chemical-genetic interaction mapping links carbon metabolism and cell wall structure to tuberculosis drug efficacy. Proceedings of the National Academy of Sciences of the United States of America 119 (15) (2022)
Lei Zhang, James E Kent, Meredith Whitaker, David C Young, Dominik Herrmann, Alexander E Aleshin, Ying-Hui Ko, Gino Cingolani, Jamil S Saad, D Branch Moody, Francesca M Marassi, Sabine Ehrt, Michael Niederweis
A periplasmic cinched protein is required for siderophore secretion and virulence of Mycobacterium tuberculosis. Nature communications 13 (1) (2022)
Kaj M Kreutzfeldt, Robert S Jansen, Travis E Hartman, Alexandre Gouzy, Ruojun Wang, Inna V Krieger, Matthew D Zimmerman, Martin Gengenbacher, Jansy P Sarathy, Min Xie, Veronique Anne Dartois, James C Sacchettini, Kyu Y Rhee, Dirk Schnappinger, Sabine Ehrt
CinA mediates multidrug tolerance in Mycobacterium tuberculosis. Nature communications 13 (1) (2022)
Alexandre Gouzy, Claire Healy, Katherine A Black, Kyu Y Rhee, Sabine Ehrt
Growth of Mycobacterium tuberculosis at acidic pH depends on lipid assimilation and is accompanied by reduced GAPDH activity. Proceedings of the National Academy of Sciences of the United States of America 118 (32) (2022)
Clare M Smith, Richard E Baker, Megan M Proulx, Bibhuti B Mishra, Jarukit E Long, Sae Woong Park, Ha-Na Lee, Michael C Kiritsy, Michelle M Bellerose, Andrew J Olive, Kenan C Murphy, Kadamba Papavinasasundaram, Frederick J Boehm, Charlotte J Reames, Rachel K Meade, Brea K Hampton, Colton L Linnertz, Ginger D Shaw, Pablo Hock, Timothy A Bell, Sabine Ehrt, Dirk Schnappinger, Fernando Pardo-Manuel de Villena, Martin T Ferris, Thomas R Ioerger, Christopher M Sassetti
Host-pathogen genetic interactions underlie tuberculosis susceptibility in genetically diverse mice. eLife 11 (2022)
Katherine A Black, Lijun Duan, Lungelo Mandyoli, Bruna P Selbach, Weizhen Xu, Sabine Ehrt, James C Sacchettini, Kyu Y Rhee
Metabolic bifunctionality of Rv0812 couples folate and peptidoglycan biosynthesis in Mycobacterium tuberculosis. The Journal of experimental medicine 218 (7) (2021)
Tiago Beites, Robert S Jansen, Ruojun Wang, Adrian Jinich, Kyu Y Rhee, Dirk Schnappinger, Sabine Ehrt
Multiple acyl-CoA dehydrogenase deficiency kills Mycobacterium tuberculosis in vitro and during infection. Nature communications 12 (1) (2021)
Sarah M Schrader, Hélène Botella, Robert S Jansen, Sabine Ehrt, Kyu Y Rhee, Carl F Nathan, Julien Vaubourgeix
Multiform antimicrobial resistance from a metabolic mutation. Science advances 7 (35) (2021)
Hongwei Su, Kan Lin, Divya Tiwari, Claire Healy, Carolina M Trujillo, Yao Liu, Thomas R Ioerger, Dirk Schnappinger, Sabine Ehrt
Genetic models of latent tuberculosis in mice reveal differential influence of adaptive immunity. The Journal of experimental medicine 218 (9) (2021)
Martin Gengenbacher, Matthew D Zimmerman, Jansy P Sarathy, Firat Kaya, Han Wang, Marizel Mina, Claire Carter, Md Amir Hossen, Hongwei Su, Carolina Trujillo, Sabine Ehrt, Dirk Schnappinger, Veronique Anne Dartois
Tissue Distribution of Doxycycline in Animal Models of Tuberculosis. Antimicrobial agents and chemotherapy 64 (5) (2020)
Claire Healy, Alexandre Gouzy, Sabine Ehrt
Peptidoglycan Hydrolases RipA and Ami1 Are Critical for Replication and Persistence of Mycobacterium tuberculosis in the Host. mBio 11 (2) (2020)
Tiago Beites, Kathryn O'Brien, Divya Tiwari, Curtis A Engelhart, Shaun Walters, Jenna Andrews, Hee-Jeong Yang, Michelle L Sutphen, Danielle M Weiner, Emmanuel K Dayao, Matthew Zimmerman, Brendan Prideaux, Prashant V Desai, Thierry Masquelin, Laura E Via, Véronique Dartois, Helena I M Boshoff, Clifton Earl Barry, Sabine Ehrt, Dirk Schnappinger
Plasticity of the Mycobacterium tuberculosis respiratory chain and its impact on tuberculosis drug development. Nature communications 10 (1) (2019)
Ruojun Wang, Kaj Kreutzfeldt, Helene Botella, Julien Vaubourgeix, Dirk Schnappinger, Sabine Ehrt
Persistent Mycobacterium tuberculosis infection in mice requires PerM for successful cell division. eLife 8 (2019)
Helene Botella, Julien Vaubourgeix, Myung Hee Lee, Naomi Song, Weizhen Xu, Hideki Makinoshima, Michael S Glickman, Sabine Ehrt
Mycobacterium tuberculosis protease MarP activates a peptidoglycan hydrolase during acid stress. The EMBO journal 36 (4) (2017)
Kan Lin, Kathryn M O'Brien, Carolina Trujillo, Ruojun Wang, Joshua B Wallach, Dirk Schnappinger, Sabine Ehrt
Mycobacterium tuberculosis Thioredoxin Reductase Is Essential for Thiol Redox Homeostasis but Plays a Minor Role in Antioxidant Defense. PLoS pathogens 12 (6) (2016)

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Publication Activity (10 Years)

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Sabine Ehrt