Pirro G Hysi (P Hysi, Pirro Hysi)

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 59

Top Topics

Chronic Obstructive Pulmonary Disease

Machine Learning

Duchenne Muscular Dystrophy

Genome Wide Association Study

Top Venues

Communications biology

Nature communications

Nature genetics

Science advances

This page only lists publications with an associated author ORCID identifier.

Publications

Bryan R Gorman, Michael Francis, Cari L Nealon, Christopher W Halladay, Nalvi Duro, Kyriacos Markianos, Giulio Genovese, Pirro G Hysi, Helene Choquet, Natalie A Afshari, Yi Ju Li, null null, J Michael Gaziano, Adriana M Hung, Wen-Chih Wu, Paul B Greenberg, Saiju Pyarajan, Jonathan H Lass, Neal S Peachey, Sudha K Iyengar
A multi-ancestry GWAS of Fuchs corneal dystrophy highlights the contributions of laminins, collagen, and endothelial cell regulation. Communications biology 7 (1) (2024)
Bryan R Gorman, Michael Francis, Cari L Nealon, Christopher W Halladay, Nalvi Duro, Kyriacos Markianos, Giulio Genovese, Pirro G Hysi, Helene Choquet, Natalie A Afshari, Yi Ju Li, null null, J Michael Gaziano, Adriana M Hung, Wen-Chih Wu, Paul B Greenberg, Saiju Pyarajan, Jonathan H Lass, Neal S Peachey, Sudha K Iyengar
A multi-ancestry GWAS of Fuchs corneal dystrophy highlights the contributions of laminins, collagen, and endothelial cell regulation. Communications biology 7 (1) (2024)
Bryan R Gorman, Michael Francis, Cari L Nealon, Christopher W Halladay, Nalvi Duro, Kyriacos Markianos, Giulio Genovese, Pirro G Hysi, Helene Choquet, Natalie A Afshari, Yi Ju Li, null null, J Michael Gaziano, Adriana M Hung, Wen-Chih Wu, Paul B Greenberg, Saiju Pyarajan, Jonathan H Lass, Neal S Peachey, Sudha K Iyengar
A multi-ancestry GWAS of Fuchs corneal dystrophy highlights the contributions of laminins, collagen, and endothelial cell regulation. Communications biology 7 (1) (2024)
Bryan R Gorman, Michael Francis, Cari L Nealon, Christopher W Halladay, Nalvi Duro, Kyriacos Markianos, Giulio Genovese, Pirro G Hysi, Helene Choquet, Natalie A Afshari, Yi Ju Li, null null, J Michael Gaziano, Adriana M Hung, Wen-Chih Wu, Paul B Greenberg, Saiju Pyarajan, Jonathan H Lass, Neal S Peachey, Sudha K Iyengar
A multi-ancestry GWAS of Fuchs corneal dystrophy highlights the contributions of laminins, collagen, and endothelial cell regulation. Communications biology 7 (1) (2024)
Bryan R Gorman, Michael Francis, Cari L Nealon, Christopher W Halladay, Nalvi Duro, Kyriacos Markianos, Giulio Genovese, Pirro G Hysi, Helene Choquet, Natalie A Afshari, Yi Ju Li, null null, J Michael Gaziano, Adriana M Hung, Wen-Chih Wu, Paul B Greenberg, Saiju Pyarajan, Jonathan H Lass, Neal S Peachey, Sudha K Iyengar
A multi-ancestry GWAS of Fuchs corneal dystrophy highlights the contributions of laminins, collagen, and endothelial cell regulation. Communications biology 7 (1) (2024)
Bryan R Gorman, Michael Francis, Cari L Nealon, Christopher W Halladay, Nalvi Duro, Kyriacos Markianos, Giulio Genovese, Pirro G Hysi, Helene Choquet, Natalie A Afshari, Yi Ju Li, null null, J Michael Gaziano, Adriana M Hung, Wen-Chih Wu, Paul B Greenberg, Saiju Pyarajan, Jonathan H Lass, Neal S Peachey, Sudha K Iyengar
A multi-ancestry GWAS of Fuchs corneal dystrophy highlights the contributions of laminins, collagen, and endothelial cell regulation. Communications biology 7 (1) (2024)
Bryan R Gorman, Michael Francis, Cari L Nealon, Christopher W Halladay, Nalvi Duro, Kyriacos Markianos, Giulio Genovese, Pirro G Hysi, Helene Choquet, Natalie A Afshari, Yi Ju Li, null null, J Michael Gaziano, Adriana M Hung, Wen-Chih Wu, Paul B Greenberg, Saiju Pyarajan, Jonathan H Lass, Neal S Peachey, Sudha K Iyengar
A multi-ancestry GWAS of Fuchs corneal dystrophy highlights the contributions of laminins, collagen, and endothelial cell regulation. Communications biology 7 (1) (2024)
Anthony M Musolf, Annechien E G Haarman, Robert N Luben, Jue-Sheng Ong, Karina Patasova, Rolando Hernandez Trapero, Joseph A Marsh, Ishika Jain, Riya Jain, Paul Zhiping Wang, Deyana D Lewis, Milly S Tedja, Adriana I Iglesias, Hengtong Li, Cameron S Cowan, null null, Ginevra Biino, Alison P Klein, Priya Duggal, David A Mackey, Caroline Hayward, Toomas Haller, Andres Metspalu, Juho Wedenoja, Olavi Pärssinen, Ching-Yu Cheng, Seang-Mei Saw, Dwight Stambolian, Pirro G Hysi, Anthony P Khawaja, Veronique Vitart, Christopher J Hammond, Cornelia M Van Duijn, Virginie J M Verhoeven, Caroline C W Klaver, Richard K Wilson
Rare variant analyses across multiethnic cohorts identify novel genes for refractive error. Communications biology 6 (1) (2023)
Xikun Han, Puya Gharahkhani, Andrew R Hamel, Jue-Sheng Ong, Miguel E Renteria, Puja A Mehta, Xianjun Dong, Francesca Pasutto, Christopher J Hammond, Terri L Young, Pirro G Hysi, Andrew John Lotery, Eric Jorgensen, Helene Choquet, Michael Hauser, Jessica N Cooke Bailey, Toru Nakazawa, Masato Akiyama, Yukihiro Shiga, Zachary L Fuller, Xin Wang, Alex W Hewitt, Jamie E Craig, Louis R Pasquale, David A Mackey, Janey L Wiggs, Anthony P Khawaja, Ayellet V Segrè, null null, null null, Stuart Macgregor
Large-scale multitrait genome-wide association analyses identify hundreds of glaucoma risk loci. Nature genetics (2023)
Nick Shrine, Abril G Izquierdo, Jing Chen, Richard Packer, Robert J Hall, Anna L Guyatt, Chiara Batini, Rebecca J Thompson, Chandan Pavuluri, Vidhi Malik, Brian D Hobbs, Matthew Moll, Wonji Kim, Ruth Tal-Singer, Per Bakke, Katherine A Fawcett, Catherine John, Kayesha Coley, Noemi Nicole Piga, Alfred Pozarickij, Kuang Lin, Iona Y Millwood, Zhengming Chen, Liming Li, null null, Sara R A Wijnant, Lies Lahousse, Guy Brusselle, Andre G Uitterlinden, Ani Manichaikul, Elizabeth C Oelsner, Stephen S Rich, R Graham Barr, Shona M Kerr, Veronique Vitart, Michael R Brown, Matthias Wielscher, Medea Imboden, Ayoung Jeong, Traci M Bartz, Sina A Gharib, Claudia Flexeder, Stefan Karrasch, Christian Gieger, Annette Peters, Beate Stubbe, Xiaowei Hu, Victor E Ortega, Deborah A Meyers, Eugene R Bleecker, Stacey B Gabriel, Namrata Gupta, Albert Vernon Smith, Jian'an Luan, Jing-Hua Zhao, Ailin F Hansen, Arnulf Langhammer, Cristen J Willer, Laxmi Bhatta, David J Porteous, Blair Hamilton Smith, Archie I Campbell, Tamar Sofer, Jiwon Lee, Martha L Daviglus, Bing Yu, Elise Lim, Hanfei Xu, George T O'Connor, Gaurav Thareja, Omar M E Albagha, null null, Karsten Suhre, Raquel Granell, Tariq O Faquih, Pieter S Hiemstra, Annelies M Slats, Benjamin H Mullin, Jennie Hui, Alan James, John Beilby, Karina Patasova, Pirro G Hysi, Jukka T Koskela, Annah B Wyss, Jianping Jin, Sinjini Sikdar, Mi Kyeong Lee, Sebastian May-Wilson, Nicola Pirastu, Katherine A Kentistou, Peter K Joshi, Paul R H J Timmers, Alexander T Williams, Robert C Free, Xueyang Wang, John L Morrison, Frank D Gilliland, Zhanghua Chen, Carol A Wang, Rachel E Foong, Sarah E Harris, Adele Taylor, Paul Redmond, James P Cook, Anubha Mahajan, Lars Lind, Teemu Palviainen, Terho Lehtimäki, Olli T Raitakari, Jaakko A Kaprio, Taina Rantanen, Kirsi H Pietiläinen, Simon R Cox, Craig E Pennell, Graham L Hall, W James Gauderman, Chris Brightling, James F Wilson, Tuula Vasankari, Tarja Laitinen, Veikko V Salomaa, Dennis O Mook-Kanamori, Nicholas John Timpson, Eleftheria Zeggini, Josée Dupuis, Caroline Hayward, Ben Michael Brumpton, Claudia Langenberg, Stefan Weiss, Georg Homuth, Carsten Oliver Schmidt, Nicole Probst-Hensch, Marjo-Riitta Jarvelin, Alanna C Morrison, Ozren Polasek, Igor Rudan, Joo-Hyeon Lee, Ian Sayers, Emma L Rawlins, Frank Dudbridge, Edwin K Silverman, David P Strachan, Robin G Walters, Andrew P Morris, Stephanie J London, Michael H Cho, Louise V Wain, Ian P Hall, Martin D Tobin
Multi-ancestry genome-wide association analyses improve resolution of genes and pathways influencing lung function and chronic obstructive pulmonary disease risk. Nature genetics 55 (3) (2023)
Nick Shrine, Abril G Izquierdo, Jing Chen, Richard Packer, Robert J Hall, Anna L Guyatt, Chiara Batini, Rebecca J Thompson, Chandan Pavuluri, Vidhi Malik, Brian D Hobbs, Matthew Moll, Wonji Kim, Ruth Tal-Singer, Per Bakke, Katherine A Fawcett, Catherine John, Kayesha Coley, Noemi Nicole Piga, Alfred Pozarickij, Kuang Lin, Iona Y Millwood, Zhengming Chen, Liming Li, null null, Sara R A Wijnant, Lies Lahousse, Guy Brusselle, Andre G Uitterlinden, Ani Manichaikul, Elizabeth C Oelsner, Stephen S Rich, R Graham Barr, Shona M Kerr, Veronique Vitart, Michael R Brown, Matthias Wielscher, Medea Imboden, Ayoung Jeong, Traci M Bartz, Sina A Gharib, Claudia Flexeder, Stefan Karrasch, Christian Gieger, Annette Peters, Beate Stubbe, Xiaowei Hu, Victor E Ortega, Deborah A Meyers, Eugene R Bleecker, Stacey B Gabriel, Namrata Gupta, Albert Vernon Smith, Jian'an Luan, Jing-Hua Zhao, Ailin F Hansen, Arnulf Langhammer, Cristen J Willer, Laxmi Bhatta, David J Porteous, Blair Hamilton Smith, Archie I Campbell, Tamar Sofer, Jiwon Lee, Martha L Daviglus, Bing Yu, Elise Lim, Hanfei Xu, George T O'Connor, Gaurav Thareja, Omar M E Albagha, null null, Karsten Suhre, Raquel Granell, Tariq O Faquih, Pieter S Hiemstra, Annelies M Slats, Benjamin H Mullin, Jennie Hui, Alan James, John Beilby, Karina Patasova, Pirro G Hysi, Jukka T Koskela, Annah B Wyss, Jianping Jin, Sinjini Sikdar, Mi Kyeong Lee, Sebastian May-Wilson, Nicola Pirastu, Katherine A Kentistou, Peter K Joshi, Paul R H J Timmers, Alexander T Williams, Robert C Free, Xueyang Wang, John L Morrison, Frank D Gilliland, Zhanghua Chen, Carol A Wang, Rachel E Foong, Sarah E Harris, Adele Taylor, Paul Redmond, James P Cook, Anubha Mahajan, Lars Lind, Teemu Palviainen, Terho Lehtimäki, Olli T Raitakari, Jaakko A Kaprio, Taina Rantanen, Kirsi H Pietiläinen, Simon R Cox, Craig E Pennell, Graham L Hall, W James Gauderman, Chris Brightling, James F Wilson, Tuula Vasankari, Tarja Laitinen, Veikko V Salomaa, Dennis O Mook-Kanamori, Nicholas John Timpson, Eleftheria Zeggini, Josée Dupuis, Caroline Hayward, Ben Michael Brumpton, Claudia Langenberg, Stefan Weiss, Georg Homuth, Carsten Oliver Schmidt, Nicole Probst-Hensch, Marjo-Riitta Jarvelin, Alanna C Morrison, Ozren Polasek, Igor Rudan, Joo-Hyeon Lee, Ian Sayers, Emma L Rawlins, Frank Dudbridge, Edwin K Silverman, David P Strachan, Robin G Walters, Andrew P Morris, Stephanie J London, Michael H Cho, Louise V Wain, Ian P Hall, Martin D Tobin
Multi-ancestry genome-wide association analyses improve resolution of genes and pathways influencing lung function and chronic obstructive pulmonary disease risk. Nature genetics 55 (3) (2023)
Anthony M Musolf, Annechien E G Haarman, Robert N Luben, Jue-Sheng Ong, Karina Patasova, Rolando Hernandez Trapero, Joseph A Marsh, Ishika Jain, Riya Jain, Paul Zhiping Wang, Deyana D Lewis, Milly S Tedja, Adriana I Iglesias, Hengtong Li, Cameron S Cowan, null null, Ginevra Biino, Alison P Klein, Priya Duggal, David A Mackey, Caroline Hayward, Toomas Haller, Andres Metspalu, Juho Wedenoja, Olavi Pärssinen, Ching-Yu Cheng, Seang-Mei Saw, Dwight Stambolian, Pirro G Hysi, Anthony P Khawaja, Veronique Vitart, Christopher J Hammond, Cornelia M Van Duijn, Virginie J M Verhoeven, Caroline C W Klaver, Richard K Wilson
Rare variant analyses across multiethnic cohorts identify novel genes for refractive error. Communications biology 6 (1) (2023)
Anthony M Musolf, Annechien E G Haarman, Robert N Luben, Jue-Sheng Ong, Karina Patasova, Rolando Hernandez Trapero, Joseph A Marsh, Ishika Jain, Riya Jain, Paul Zhiping Wang, Deyana D Lewis, Milly S Tedja, Adriana I Iglesias, Hengtong Li, Cameron S Cowan, null null, Ginevra Biino, Alison P Klein, Priya Duggal, David A Mackey, Caroline Hayward, Toomas Haller, Andres Metspalu, Juho Wedenoja, Olavi Pärssinen, Ching-Yu Cheng, Seang-Mei Saw, Dwight Stambolian, Pirro G Hysi, Anthony P Khawaja, Veronique Vitart, Christopher J Hammond, Cornelia M Van Duijn, Virginie J M Verhoeven, Caroline C W Klaver, Richard K Wilson
Rare variant analyses across multiethnic cohorts identify novel genes for refractive error. Communications biology 6 (1) (2023)
Hamdi Mbarek, Scott D Gordon, David L Duffy, Nikki Hubers, Sally Mortlock, Jeffrey J Beck, Jouke-Jan Hottenga, René Pool, Conor V Dolan, Ky'Era V Actkins, Zachary F Gerring, Jenny Van Dongen, Erik A Ehli, William G Iacono, Matt Mcgue, Daniel I Chasman, C Scott Gallagher, Samantha L P Schilit, Cynthia C Morton, Guillaume Paré, Gonneke Willemsen, David C Whiteman, Catherine M Olsen, Catherine Derom, Robert Vlietinck, Daniel Gudbjartsson, Lisa Cannon-Albright, Eva Krapohl, Robert Plomin, Patrik K E Magnusson, Nancy L Pedersen, Pirro G Hysi, Massimo Mangino, Timothy D Spector, Teemu Palviainen, Yuri Milaneschi, Brenda W Penninnx, Adrian I Campos, Ken K Ong, John R B Perry, Cornelis Nils Lambalk, Jaakko Kaprio, Ísleifur Ólafsson, Karine Duroure, Céline Revenu, Miguel E Rentería, Loic Yengo, Lea Davis, Eske M Derks, Sarah E Medland, Hreinn Stefansson, Kari Stefansson, Filippo Del Bene, Bruno Reversade, Grant W Montgomery, Dorret I Boomsma, Nicholas G Martin
Genome-wide association study meta-analysis of dizygotic twinning illuminates genetic regulation of female fecundity. Human reproduction (Oxford, England) (2023)
Ashley van der Spek, Isobel D Stewart, Brigitte Kühnel, Maik Pietzner, Tahani Alshehri, Friederike Gauß, Pirro G Hysi, Siamak MahmoudianDehkordi, Almut Heinken, Annemarie I Luik, Karl-Heinz Ladwig, Gabi Kastenmüller, Cristina Menni, Johannes Hertel, Mohammad Arfan Ikram, Renée de Mutsert, Karsten Suhre, Christian Gieger, Konstantin Strauch, Henry Völzke, Thomas Meitinger, Massimo Mangino, Antonia Flaquer, Melanie Waldenberger, Annette Peters, Ines Thiele, Rima Kaddurah-Daouk, Boadie W Dunlop, Frits R Rosendaal, Nicholas J Wareham, Tim D Spector, Sonja Kunze, Hans Jörgen Grabe, Dennis O Mook-Kanamori, Claudia Langenberg, Cornelia M Van Duijn, Ivana Nedeljković
Circulating metabolites modulated by diet are associated with depression. Molecular psychiatry (2023)
Nick Shrine, Abril G Izquierdo, Jing Chen, Richard Packer, Robert J Hall, Anna L Guyatt, Chiara Batini, Rebecca J Thompson, Chandan Pavuluri, Vidhi Malik, Brian D Hobbs, Matthew Moll, Wonji Kim, Ruth Tal-Singer, Per Bakke, Katherine A Fawcett, Catherine John, Kayesha Coley, Noemi Nicole Piga, Alfred Pozarickij, Kuang Lin, Iona Y Millwood, Zhengming Chen, Liming Li, null null, Sara R A Wijnant, Lies Lahousse, Guy Brusselle, Andre G Uitterlinden, Ani Manichaikul, Elizabeth C Oelsner, Stephen S Rich, R Graham Barr, Shona M Kerr, Veronique Vitart, Michael R Brown, Matthias Wielscher, Medea Imboden, Ayoung Jeong, Traci M Bartz, Sina A Gharib, Claudia Flexeder, Stefan Karrasch, Christian Gieger, Annette Peters, Beate Stubbe, Xiaowei Hu, Victor E Ortega, Deborah A Meyers, Eugene R Bleecker, Stacey B Gabriel, Namrata Gupta, Albert Vernon Smith, Jian'an Luan, Jing-Hua Zhao, Ailin F Hansen, Arnulf Langhammer, Cristen J Willer, Laxmi Bhatta, David J Porteous, Blair Hamilton Smith, Archie I Campbell, Tamar Sofer, Jiwon Lee, Martha L Daviglus, Bing Yu, Elise Lim, Hanfei Xu, George T O'Connor, Gaurav Thareja, Omar M E Albagha, null null, Karsten Suhre, Raquel Granell, Tariq O Faquih, Pieter S Hiemstra, Annelies M Slats, Benjamin H Mullin, Jennie Hui, Alan James, John Beilby, Karina Patasova, Pirro G Hysi, Jukka T Koskela, Annah B Wyss, Jianping Jin, Sinjini Sikdar, Mi Kyeong Lee, Sebastian May-Wilson, Nicola Pirastu, Katherine A Kentistou, Peter K Joshi, Paul R H J Timmers, Alexander T Williams, Robert C Free, Xueyang Wang, John L Morrison, Frank D Gilliland, Zhanghua Chen, Carol A Wang, Rachel E Foong, Sarah E Harris, Adele Taylor, Paul Redmond, James P Cook, Anubha Mahajan, Lars Lind, Teemu Palviainen, Terho Lehtimäki, Olli T Raitakari, Jaakko A Kaprio, Taina Rantanen, Kirsi H Pietiläinen, Simon R Cox, Craig E Pennell, Graham L Hall, W James Gauderman, Chris Brightling, James F Wilson, Tuula Vasankari, Tarja Laitinen, Veikko V Salomaa, Dennis O Mook-Kanamori, Nicholas John Timpson, Eleftheria Zeggini, Josée Dupuis, Caroline Hayward, Ben Michael Brumpton, Claudia Langenberg, Stefan Weiss, Georg Homuth, Carsten Oliver Schmidt, Nicole Probst-Hensch, Marjo-Riitta Jarvelin, Alanna C Morrison, Ozren Polasek, Igor Rudan, Joo-Hyeon Lee, Ian Sayers, Emma L Rawlins, Frank Dudbridge, Edwin K Silverman, David P Strachan, Robin G Walters, Andrew P Morris, Stephanie J London, Michael H Cho, Louise V Wain, Ian P Hall, Martin D Tobin
Multi-ancestry genome-wide association analyses improve resolution of genes and pathways influencing lung function and chronic obstructive pulmonary disease risk. Nature genetics 55 (3) (2023)
Anthony M Musolf, Annechien E G Haarman, Robert N Luben, Jue-Sheng Ong, Karina Patasova, Rolando Hernandez Trapero, Joseph A Marsh, Ishika Jain, Riya Jain, Paul Zhiping Wang, Deyana D Lewis, Milly S Tedja, Adriana I Iglesias, Hengtong Li, Cameron S Cowan, null null, Ginevra Biino, Alison P Klein, Priya Duggal, David A Mackey, Caroline Hayward, Toomas Haller, Andres Metspalu, Juho Wedenoja, Olavi Pärssinen, Ching-Yu Cheng, Seang-Mei Saw, Dwight Stambolian, Pirro G Hysi, Anthony P Khawaja, Veronique Vitart, Christopher J Hammond, Cornelia M Van Duijn, Virginie J M Verhoeven, Caroline C W Klaver, Richard K Wilson
Rare variant analyses across multiethnic cohorts identify novel genes for refractive error. Communications biology 6 (1) (2023)
Oana A Zeleznik, Jae Hee Kang, Jessica A Lasky-Su, A Heather Eliassen, Lisa Frueh, Andrew T Chan, Bernard A Rosner, Tobias Elze, Pirro G Hysi, Anthony P Khawaja, Janey L Wiggs, Louis R Pasquale, null null
Plasma metabolite profile for primary open-angle glaucoma in three US cohorts and the UK Biobank. Nature communications 14 (1) (2023)
Neal Peachey, Bryan R Gorman, Michael Francis, Cari Nealon, Christopher Halladay, Nalvi Duro, Kyriacos Markianos, Giulio Genovese, Pirro G Hysi, Helene Choquet, Natalie Afshari, Yi Ju Li, J Michael Gaziano, Adriana Hung, Wen-Chih Wu, Paul Greenberg, Saiju Pyarajan, Jonathan Lass, Sudha Iyengar
Multi-ancestry GWAS of Fuchs corneal dystrophy highlights roles of laminins, collagen, and endothelial cell regulation. Research square (2023)
Oana A Zeleznik, Jae Hee Kang, Jessica A Lasky-Su, A Heather Eliassen, Lisa Frueh, Andrew T Chan, Bernard A Rosner, Tobias Elze, Pirro G Hysi, Anthony P Khawaja, Janey L Wiggs, Louis R Pasquale, null null
Plasma metabolite profile for primary open-angle glaucoma in three US cohorts and the UK Biobank. Nature communications 14 (1) (2023)
Ashley Budu-Aggrey, Anna Kilanowski, Maria K Sobczyk, null null, Suyash S Shringarpure, Ruth E Mitchell, Kadri Reis, Anu Reigo, null null, Reedik Mägi, Mari Nelis, Nao Tanaka, Ben Michael Brumpton, Laurent F Thomas, Pol Sole Navais, Christopher Flatley, Antonio Espuela-Ortiz, Esther Herrera-Luis, Jesus V T Lominchar, Jette Bork-Jensen, Ingo Marenholz, Aleix Arnau-Soler, Ayoung Jeong, Katherine A Fawcett, Hansjorg Baurecht, Elke Rodriguez, Alexessander Couto Alves, Ashish Kumar, Patrick M Sleiman, Xiao Chang, Carolina Medina-Gomez, Chen Hu, Cheng-Jian Xu, Cancan Qi, Sarah El-Heis, Philip Titcombe, Elie Antoun, João Fadista, Carol A Wang, Elisabeth Thiering, Baojun Wu, Sara Kress, Dilini M Kothalawala, Latha Kadalayil, Jiasong Duan, Hongmei Zhang, Sabelo Hadebe, Thomas J Hoffmann, Eric Jorgenson, Helene Choquet, Neil Risch, Pal Rasmus Njolstad, Ole Andreas Andreassen, Stefan E Johansson, Catarina Almqvist, Tong Gong, Vilhelmina Ullemar, Robert Karlsson, Patrik K E Magnusson, Agnieszka Szwajda, Esteban González Burchard, Jacob P Thyssen, Torben Hansen, Line L Kårhus, Thomas M Dantoft, Alexander C S N Jeanrenaud, Ahla Ghauri, Andreas Arnold, Georg Homuth, Susanne Lau, Markus Maria Nöthen, Norbert Hübner, Medea Imboden, Alessia Visconti, Mario Falchi, Veronique Bataille, Pirro G Hysi, Natalia Ballardini, Dorret I Boomsma, Jouke- Jan Hottenga, Martina Müller-Nurasyid, Tarunveer Singh Ahluwalia, Jessica Lasky-Su, Bo Lund Chawes, Ann-Marie Malby Schoos, Ana Esplugues, Mariona Bustamante, Benjamin Raby, Syed Arshad, Chris German, Tõnu Esko, Lili A Milani, Andres Metspalu, Chikashi C Terao, Katrina Abuabara, Mari Løset, Kristian Hveem, Bo Jacobson, Maria Pino-Yanes, David P Strachan, Niels Grarup, Allan Linneberg, Young-Ae Lee, Nicole Probst-Hensch, Stephan Weidinger, Marjo-Riitta Jarvelin, Erik Melén, Hakon H Hakonarson, Alan D Irvine, Deborah Jarvis, Tamar E C Nijsten, Liesbeth Duijts, Judith E Vonk, Gerard H Koppelmann, Keith M Godfrey, Sheila J Barton, Bjarke Feenstra, Craig E Pennell, Peter D Sly, Patrick G Holt, L Keoki Williams, Hans Bisgaard, Klaus Bønnelykke, John Curtin, Angela Simpson, Clare S Murray, Tamara Schikowski, Supinda Bunyavanich, Scott T Weiss, John W Holloway, Josine L Min, Sara J Brown, Marie Standl, Lavinia Paternoster
European and multi-ancestry genome-wide association meta-analysis of atopic dermatitis highlights importance of systemic immune regulation. Nature communications 14 (1) (2023)
Anthony M Musolf, Annechien E G Haarman, Robert N Luben, Jue-Sheng Ong, Karina Patasova, Rolando Hernandez Trapero, Joseph A Marsh, Ishika Jain, Riya Jain, Paul Zhiping Wang, Deyana D Lewis, Milly S Tedja, Adriana I Iglesias, Hengtong Li, Cameron S Cowan, null null, Ginevra Biino, Alison P Klein, Priya Duggal, David A Mackey, Caroline Hayward, Toomas Haller, Andres Metspalu, Juho Wedenoja, Olavi Pärssinen, Ching-Yu Cheng, Seang-Mei Saw, Dwight Stambolian, Pirro G Hysi, Anthony P Khawaja, Veronique Vitart, Christopher J Hammond, Cornelia M Van Duijn, Virginie J M Verhoeven, Caroline C W Klaver, Richard K Wilson
Rare variant analyses across multiethnic cohorts identify novel genes for refractive error. Communications biology 6 (1) (2023)
Neal Peachey, Bryan R Gorman, Michael Francis, Cari Nealon, Christopher Halladay, Nalvi Duro, Kyriacos Markianos, Giulio Genovese, Pirro G Hysi, Helene Choquet, Natalie Afshari, Yi Ju Li, J Michael Gaziano, Adriana Hung, Wen-Chih Wu, Paul Greenberg, Saiju Pyarajan, Jonathan Lass, Sudha Iyengar
Multi-ancestry GWAS of Fuchs corneal dystrophy highlights roles of laminins, collagen, and endothelial cell regulation. Research square (2023)
Oana A Zeleznik, Jae Hee Kang, Jessica A Lasky-Su, A Heather Eliassen, Lisa Frueh, Andrew T Chan, Bernard A Rosner, Tobias Elze, Pirro G Hysi, Anthony P Khawaja, Janey L Wiggs, Louis R Pasquale, null null
Plasma metabolite profile for primary open-angle glaucoma in three US cohorts and the UK Biobank. Nature communications 14 (1) (2023)
Nick Shrine, Abril G Izquierdo, Jing Chen, Richard Packer, Robert J Hall, Anna L Guyatt, Chiara Batini, Rebecca J Thompson, Chandan Pavuluri, Vidhi Malik, Brian D Hobbs, Matthew Moll, Wonji Kim, Ruth Tal-Singer, Per Bakke, Katherine A Fawcett, Catherine John, Kayesha Coley, Noemi Nicole Piga, Alfred Pozarickij, Kuang Lin, Iona Y Millwood, Zhengming Chen, Liming Li, null null, Sara R A Wijnant, Lies Lahousse, Guy Brusselle, Andre G Uitterlinden, Ani Manichaikul, Elizabeth C Oelsner, Stephen S Rich, R Graham Barr, Shona M Kerr, Veronique Vitart, Michael R Brown, Matthias Wielscher, Medea Imboden, Ayoung Jeong, Traci M Bartz, Sina A Gharib, Claudia Flexeder, Stefan Karrasch, Christian Gieger, Annette Peters, Beate Stubbe, Xiaowei Hu, Victor E Ortega, Deborah A Meyers, Eugene R Bleecker, Stacey B Gabriel, Namrata Gupta, Albert Vernon Smith, Jian'an Luan, Jing-Hua Zhao, Ailin F Hansen, Arnulf Langhammer, Cristen J Willer, Laxmi Bhatta, David J Porteous, Blair Hamilton Smith, Archie I Campbell, Tamar Sofer, Jiwon Lee, Martha L Daviglus, Bing Yu, Elise Lim, Hanfei Xu, George T O'Connor, Gaurav Thareja, Omar M E Albagha, null null, Karsten Suhre, Raquel Granell, Tariq O Faquih, Pieter S Hiemstra, Annelies M Slats, Benjamin H Mullin, Jennie Hui, Alan James, John Beilby, Karina Patasova, Pirro G Hysi, Jukka T Koskela, Annah B Wyss, Jianping Jin, Sinjini Sikdar, Mi Kyeong Lee, Sebastian May-Wilson, Nicola Pirastu, Katherine A Kentistou, Peter K Joshi, Paul R H J Timmers, Alexander T Williams, Robert C Free, Xueyang Wang, John L Morrison, Frank D Gilliland, Zhanghua Chen, Carol A Wang, Rachel E Foong, Sarah E Harris, Adele Taylor, Paul Redmond, James P Cook, Anubha Mahajan, Lars Lind, Teemu Palviainen, Terho Lehtimäki, Olli T Raitakari, Jaakko A Kaprio, Taina Rantanen, Kirsi H Pietiläinen, Simon R Cox, Craig E Pennell, Graham L Hall, W James Gauderman, Chris Brightling, James F Wilson, Tuula Vasankari, Tarja Laitinen, Veikko V Salomaa, Dennis O Mook-Kanamori, Nicholas John Timpson, Eleftheria Zeggini, Josée Dupuis, Caroline Hayward, Ben Michael Brumpton, Claudia Langenberg, Stefan Weiss, Georg Homuth, Carsten Oliver Schmidt, Nicole Probst-Hensch, Marjo-Riitta Jarvelin, Alanna C Morrison, Ozren Polasek, Igor Rudan, Joo-Hyeon Lee, Ian Sayers, Emma L Rawlins, Frank Dudbridge, Edwin K Silverman, David P Strachan, Robin G Walters, Andrew P Morris, Stephanie J London, Michael H Cho, Louise V Wain, Ian P Hall, Martin D Tobin
Multi-ancestry genome-wide association analyses improve resolution of genes and pathways influencing lung function and chronic obstructive pulmonary disease risk. Nature genetics 55 (3) (2023)
Anthony M Musolf, Annechien E G Haarman, Robert N Luben, Jue-Sheng Ong, Karina Patasova, Rolando Hernandez Trapero, Joseph A Marsh, Ishika Jain, Riya Jain, Paul Zhiping Wang, Deyana D Lewis, Milly S Tedja, Adriana I Iglesias, Hengtong Li, Cameron S Cowan, null null, Ginevra Biino, Alison P Klein, Priya Duggal, David A Mackey, Caroline Hayward, Toomas Haller, Andres Metspalu, Juho Wedenoja, Olavi Pärssinen, Ching-Yu Cheng, Seang-Mei Saw, Dwight Stambolian, Pirro G Hysi, Anthony P Khawaja, Veronique Vitart, Christopher J Hammond, Cornelia M Van Duijn, Virginie J M Verhoeven, Caroline C W Klaver, Richard K Wilson
Rare variant analyses across multiethnic cohorts identify novel genes for refractive error. Communications biology 6 (1) (2023)
Wendy W Liu, Tyler G Kinzy, Jessica N Cooke Bailey, Zihe Xu, Pirro G Hysi, Janey L Wiggs, null null
Mechanosensitive ion channel gene survey suggests potential roles in primary open angle glaucoma. Scientific reports 13 (1) (2023)
Nick Shrine, Abril G Izquierdo, Jing Chen, Richard Packer, Robert J Hall, Anna L Guyatt, Chiara Batini, Rebecca J Thompson, Chandan Pavuluri, Vidhi Malik, Brian D Hobbs, Matthew Moll, Wonji Kim, Ruth Tal-Singer, Per Bakke, Katherine A Fawcett, Catherine John, Kayesha Coley, Noemi Nicole Piga, Alfred Pozarickij, Kuang Lin, Iona Y Millwood, Zhengming Chen, Liming Li, null null, Sara R A Wijnant, Lies Lahousse, Guy Brusselle, Andre G Uitterlinden, Ani Manichaikul, Elizabeth C Oelsner, Stephen S Rich, R Graham Barr, Shona M Kerr, Veronique Vitart, Michael R Brown, Matthias Wielscher, Medea Imboden, Ayoung Jeong, Traci M Bartz, Sina A Gharib, Claudia Flexeder, Stefan Karrasch, Christian Gieger, Annette Peters, Beate Stubbe, Xiaowei Hu, Victor E Ortega, Deborah A Meyers, Eugene R Bleecker, Stacey B Gabriel, Namrata Gupta, Albert Vernon Smith, Jian'an Luan, Jing-Hua Zhao, Ailin F Hansen, Arnulf Langhammer, Cristen J Willer, Laxmi Bhatta, David J Porteous, Blair Hamilton Smith, Archie I Campbell, Tamar Sofer, Jiwon Lee, Martha L Daviglus, Bing Yu, Elise Lim, Hanfei Xu, George T O'Connor, Gaurav Thareja, Omar M E Albagha, null null, Karsten Suhre, Raquel Granell, Tariq O Faquih, Pieter S Hiemstra, Annelies M Slats, Benjamin H Mullin, Jennie Hui, Alan James, John Beilby, Karina Patasova, Pirro G Hysi, Jukka T Koskela, Annah B Wyss, Jianping Jin, Sinjini Sikdar, Mi Kyeong Lee, Sebastian May-Wilson, Nicola Pirastu, Katherine A Kentistou, Peter K Joshi, Paul R H J Timmers, Alexander T Williams, Robert C Free, Xueyang Wang, John L Morrison, Frank D Gilliland, Zhanghua Chen, Carol A Wang, Rachel E Foong, Sarah E Harris, Adele Taylor, Paul Redmond, James P Cook, Anubha Mahajan, Lars Lind, Teemu Palviainen, Terho Lehtimäki, Olli T Raitakari, Jaakko A Kaprio, Taina Rantanen, Kirsi H Pietiläinen, Simon R Cox, Craig E Pennell, Graham L Hall, W James Gauderman, Chris Brightling, James F Wilson, Tuula Vasankari, Tarja Laitinen, Veikko V Salomaa, Dennis O Mook-Kanamori, Nicholas John Timpson, Eleftheria Zeggini, Josée Dupuis, Caroline Hayward, Ben Michael Brumpton, Claudia Langenberg, Stefan Weiss, Georg Homuth, Carsten Oliver Schmidt, Nicole Probst-Hensch, Marjo-Riitta Jarvelin, Alanna C Morrison, Ozren Polasek, Igor Rudan, Joo-Hyeon Lee, Ian Sayers, Emma L Rawlins, Frank Dudbridge, Edwin K Silverman, David P Strachan, Robin G Walters, Andrew P Morris, Stephanie J London, Michael H Cho, Louise V Wain, Ian P Hall, Martin D Tobin
Author Correction: Multi-ancestry genome-wide association analyses improve resolution of genes and pathways influencing lung function and chronic obstructive pulmonary disease risk. Nature genetics (2023)
Rosie Clark, Alfred Pozarickij, Pirro G Hysi, Kyoko Ohno-Matsui, Cathy Williams, Jeremy A Guggenheim, null null
Education interacts with genetic variants near GJD2, RBFOX1, LAMA2, KCNQ5 and LRRC4C to confer susceptibility to myopia. PLoS genetics 18 (11) (2022)
Yan Chen, Pirro G Hysi, Carlo Maj, Stefanie Heilmann-Heimbach, Timothy D Spector, Fan Liu, Manfred Kayser
Genetic prediction of male pattern baldness based on large independent datasets. European journal of human genetics : EJHG (2022)
Karina Patasova, Annechien E G Haarman, Anthony M Musolf, Omar A Mahroo, Jugnoo Sangeeta Rahi, Mario Falchi, Virginie J M Verhoeven, Richard K Wilson, Caroline C W Klaver, Priya Duggal, Alison Klein, Jeremy A Guggenheim, Christopher J Hammond, Pirro G Hysi, null null
Association analyses of rare variants identify two genes associated with refractive error. PloS one 17 (9) (2022)
Karina Patasova, Anthony P Khawaja, Robert Wojciechowski, Omar A Mahroo, Mario Falchi, Jugnoo S Rahi, Chris J Hammond, Pirro G Hysi, null null
A genome-wide analysis of 340 318 participants identifies four novel loci associated with the age of first spectacle wear. Human molecular genetics 31 (17) (2022)
Anindyt Nagar, Panayiotis Maghsoudlou, R Wormald, Keith Barton, Pirro G Hysi, Kin Sheng Lim
Differences in the Surgical Outcomes of Glaucoma Surgery in Patients of African Caribbean Descent. Current eye research 47 (12) (2022)
Jeremy A Guggenheim, Rosie Clark, Jiangtian Cui, Louise Terry, Karina Patasova, Annechien E G Haarman, Anthony M Musolf, Virginie J M Verhoeven, Caroline C W Klaver, Richard K Wilson, Pirro G Hysi, Cathy Williams, null null, null null
Whole exome sequence analysis in 51 624 participants identifies novel genes and variants associated with refractive error and myopia. Human molecular genetics 31 (11) (2022)
Sarah Grosche, Ingo Marenholz, Jorge Esparza-Gordillo, Aleix Arnau-Soler, Erola Pairo-Castineira, Franz Rüschendorf, Tarunveer Singh Ahluwalia, Catarina Almqvist, Andreas Arnold, null null, Hansjoerg Baurecht, Hans Bisgaard, Klaus Bønnelykke, Sara J Brown, Mariona Bustamante, John A Curtin, Adnan Custovic, Shyamali C Dharmage, Ana Esplugues, Mario Falchi, Dietmar Fernández-Orth, Manuel A R Ferreira, Andre Franke, Sascha Gerdes, Christian Gieger, Hakon H Hakonarson, Patrick G Holt, Georg Homuth, Norbert Hübner, Pirro G Hysi, Marjo-Riitta Jarvelin, Robert Karlsson, Gerard H Koppelmann, Susanne Lau, Manuel Lutz, Patrik K E Magnusson, Guy B Marks, Martina Müller-Nuraysid, Markus Maria Nöthen, Lavinia Paternoster, Craig E Pennell, Annette Peters, Konrad Rawlik, Colin F Robertson, Elke Rodriguez, Sylvain Sebert, Angela Simpson, Patrick M A Sleiman, Marie Standl, Dora Stölzl, Konstantin Strauch, Agnieszka Szwajda, Albert Tenesa, Philip J Thompson, Vilhelmina Ullemar, Alessia Visconti, Judith E Vonk, Carol A Wang, Stephan Weidinger, Matthias Wielscher, Catherine L Worth, Chen-Jian Xu, Young-Ae Lee
Rare variant analysis in eczema identifies exonic variants in DUSP1, NOTCH4 and SLC9A4. Nature communications 12 (1) (2021)
Betty Bonfante, Pierre Faux, Nicolas Navarro, Javier Mendoza-Revilla, Morgane Dubied, Charlotte Montillot, Emma Wentworth, Lauriane Poloni, Ceferino Varón-González, Philip Jones, Ziyi Xiong, Macarena Fuentes-Guajardo, Sagnik Palmal, Juan Camilo Chacón-Duque, Malena Hurtado, Valeria Villegas, Vanessa Granja, Claudia Jaramillo, William Arias, Rodrigo Barquera-Lozano, Paola Everardo-Martínez, Mirsha Sánchez-Quinto, Jorge Gómez-Valdés, Hugo Villamil-Ramírez, Caio C Silva de Cerqueira, Tábita Hünemeier, Virginia Ramallo, Fan Liu, Seth M Weinberg, John R Shaffer, Evie Stergiakouli, Laurence J Howe, Pirro G Hysi, Timothy D Spector, Rolando Gonzalez-José, Lavinia Schüler-Faccini, Maria-Cátira Bortolini, Victor Acuña-Alonzo, Samuel Canizales-Quinteros, Carla Gallo, Giovanni Poletti, Gabriel Bedoya, Francisco Rothhammer, Christel Thauvin-Robinet, Laurence Faivre, Caroline Costedoat, David Balding, Timothy Cox, Manfred Kayser, Laurence Duplomb, Binnaz Yalcin, Justin Cotney, Kaustubh Adhikari, Andrés Ruiz-Linares
A GWAS in Latin Americans identifies novel face shape loci, implicating VPS13B and a Denisovan introgressed region in facial variation. Science advances 7 (6) (2021)
Sana Hamid, Parul Desai, Pirro G Hysi, Jennifer M Burr, Anthony P Khawaja
Population screening for glaucoma in UK: current recommendations and future directions. Eye (London, England) (2021)
Puya Gharahkhani, Eric Jorgensen, Pirro G Hysi, Anthony P Khawaja, Sarah Pendergrass, Xikun Han, Jue-Sheng Ong, Alex W Hewitt, Ayellet V Segrè, John M Rouhana, Andrew R Hamel, Robert P Igo, Helene Choquet, Ayub Qassim, Navya Shilpa Josyula, Jessica N Cooke Bailey, Pieter W M Bonnemaijer, Adriana I Iglesias, Owen M Siggs, Terri L Young, Veronique Vitart, Alberta A H J Thiadens, Juha Karjalainen, Steffen Uebe, Ronald B Melles, K Saidas Nair, Robert N Luben, Mark J Simcoe, Nishani Amersinghe, Angela Jane Cree, Rene Hohn, Alicia Poplawski, Li Jia Chen, Shi Song Rong, Tin Aung, Eranga Nishanthie Vithana, null null, null null, null null, null null, null null, null null, null null, Gen Tamiya, Yukihiro Shiga, Masayuki Yamamoto, Toru Nakazawa, Hannah Currant, Ewan Birney, Xin Wang, Adam Auton, Michelle K Lupton, Nicholas G Martin, Adeyinka Ashaye, Olusola Oluyinka Olawoye, Susan Eileen Isabella Williams, Stephen Akafo, Michelle Ramsay, Kazuki Hashimoto, Yoichiro Kamatani, Masato Akiyama, Yukihide Momozawa, Paul J Foster, Peng Tee Khaw, James E Morgan, Nicholas G Strouthidis, Peter Kraft, Jae Hee Kang, Chi Pui Pang, Francesca Pasutto, Paul Mitchell, Andrew John Lotery, Aarno Palotie, Cornelia van Duijn, Jonathan L Haines, Christopher J Hammond, Louis R Pasquale, Caroline C W Klaver, Michael Hauser, Chiea Chuen Khor, David A Mackey, Michiaki Kubo, Ching-Yu Cheng, Jamie E Craig, Stuart Macgregor, Janey L Wiggs
Genome-wide meta-analysis identifies 127 open-angle glaucoma loci with consistent effect across ancestries. Nature communications 12 (1) (2021)
Hannah Currant, Pirro G Hysi, Tomas W Fitzgerald, Puya Gharahkhani, Pieter W M Bonnemaijer, Anne Senabouth, Alex W Hewitt, null null, null null, Denize Atan, Tin Aung, Jason Charng, Helene Choquet, Jamie Craig, Peng T Khaw, Caroline C W Klaver, Michiaki Kubo, Jue-Sheng Ong, Louis R Pasquale, Charles A Reisman, Maciej S Daniszewski, Joseph E Powell, Alice Pébay, Mark J Simcoe, Alberta A H J Thiadens, Cornelia M Van Duijn, Seyhan Yazar, Eric Jorgensen, Stuart Macgregor, Christopher J Hammond, David A Mackey, Janey L Wiggs, Paul J Foster, Praveen J Patel, Ewan Birney, Anthony P Khawaja
Genetic variation affects morphological retinal phenotypes extracted from UK Biobank optical coherence tomography images. PLoS genetics 17 (5) (2021)
Mark J Simcoe, Ana M Valdes, Fan Liu, Nicholas A Furlotte, David M Evans, Gibran Hemani, Susan M Ring, George Davey Smith, David L Duffy, Gu Zhu, Scott D Gordon, Sarah E Medland, Dragana Vuckovic, Giorgia Girotto, Cinzia Felicita Sala, Eulalia Catamo, Maria Pina Concas, Marco Brumat, Paolo Gasparini, Daniela Toniolo, Massimiliano Cocca, Antonietta Robino, Seyhan Yazar, Alex W Hewitt, Wenting Wu, Peter Kraft, Christopher J Hammond, Yuan Shi, Yan Chen, Changqing Zeng, Caroline C W Klaver, Andre G Uitterlinden, M Arfan Ikram, Merel A Hamer, Cornelia M Van Duijn, Tamar E C Nijsten, Jiali Han, David A Mackey, Nicholas G Martin, Ching-Yu Cheng, null null, null null, David A Hinds, Timothy D Spector, Manfred Kayser, Pirro G Hysi
Genome-wide association study in almost 195,000 individuals identifies 50 previously unidentified genetic loci for eye color. Science advances 7 (11) (2021)
Howard Maile, Ji-Peng Olivia Li, Daniel Gore, Marcello Leucci, Pádraig J Mulholland, Scott C Hau, Anita Szabo, Ismail Moghul, Konstantinos Balaskas, Kaoru Fujinami, Pirro G Hysi, Alice E Davidson, Petra Liskova, Alison J Hardcastle, Stephen J Tuft, Nikolas Pontikos
Machine Learning Algorithms to Detect Subclinical Keratoconus: Systematic Review. JMIR medical informatics 9 (12) (2021)
Helene Choquet, Ronald B Melles, Deepti Anand, Jie Yin, Gabriel Cuellar-Partida, Wei Wang, null null, Thomas J Hoffmann, K Saidas Nair, Pirro G Hysi, Salil A Lachke, Eric Jorgensen
A large multiethnic GWAS meta-analysis of cataract identifies new risk loci and sex-specific effects. Nature communications 12 (1) (2021)
Richard J Acton, Wei Yuan, Fei Gao, Yudong Xia, Emma Bourne, Eva Wozniak, Jordana T Bell, Karen Lillycrop, Jun Wang, Elaine Dennison, Nicholas C W Harvey, Charles A Mein, Timothy D Spector, Pirro G Hysi, Cyrus Cooper, Christopher G Bell
The genomic loci of specific human tRNA genes exhibit ageing-related DNA hypermethylation. Nature communications 12 (1) (2021)
Alison J Hardcastle, Petra Liskova, Yelena Bykhovskaya, Bennet J McComish, Alice E Davidson, Chris F Inglehearn, Xiaohui Li, Helene Choquet, Mahmoud Habeeb, Sionne E M Lucas, Srujana Sahebjada, Nikolas Pontikos, Karla E Rojas Lopez, Anthony P Khawaja, Manir Ali, Lubica Dudakova, Pavlina Skalicka, Bart T H Van Dooren, Annette J M Geerards, Christoph Walter Haudum, Valeria Lo Faro, Abi Tenen, Mark J Simcoe, Karina Patasova, Darioush Yarrand, Jie Yin, Salina Siddiqui, Aine Rice, Layal Abi Farraj, Yii-Der Ida Chen, Jugnoo S Rahi, Ronald M Krauss, Elisabeth Theusch, Jac C Charlesworth, Loretta Szczotka-Flynn, Carmel Toomes, Magda A Meester-Smoor, Andrea J Richardson, Paul A Mitchell, Kent D Taylor, Ronald B Melles, Anthony J Aldave, Richard A Mills, Ke Cao, Elsie Chan, Mark D Daniell, Jie Jing Wang, Jerome I Rotter, Alex W Hewitt, Stuart Macgregor, Caroline C W Klaver, Wishal D Ramdas, Jamie E Craig, Sudha K Iyengar, David O'Brart, Eric Jorgensen, Paul N Baird, Yaron S Rabinowitz, Kathryn P Burdon, Christopher J Hammond, Stephen J Tuft, Pirro G Hysi
A multi-ethnic genome-wide association study implicates collagen matrix integrity and cell differentiation pathways in keratoconus. Communications biology 4 (1) (2021)
Jamie E Craig, Xikun Han, Ayub Qassim, Mark M Hassall, Jessica N Cooke Bailey, Tyler G Kinzy, Anthony P Khawaja, Jiyuan An, Henry Marshall, Puya Gharahkhani, Robert P Igo, Stuart L Graham, Paul R Healey, Jue-Sheng Ong, Tiger Zhou, Owen M Siggs, Matthew H Law, Emmanuelle Souzeau, Bronwyn Ridge, Pirro G Hysi, Kathryn P Burdon, Richard A Mills, John Landers, Jonathan B Ruddle, Ashish Agar, Anna Galanopoulos, Andrew J R White, Colin Eric Willoughby, Nicholas H Andrew, Stephen Best, Andrea L Vincent, Ivan Goldberg, Graham L Radford-Smith, Nicholas G Martin, Grant W Montgomery, Veronique Vitart, Rene Hoehn, Robert Wojciechowski, Jost Bruno Jonas, Tin Aung, Louis R Pasquale, Angela Jane Cree, Sobha Sivaprasad, Neeru A Vallabh, null null, null null, Ananth C Viswanathan, Francesca Pasutto, Jonathan L Haines, Caroline C W Klaver, Cornelia M van Duijn, Robert J Casson, Paul J Foster, Peng Tee Khaw, Christopher J Hammond, David A Mackey, Paul Mitchell, Andrew John Lotery, Janey L Wiggs, Alex W Hewitt, Stuart Macgregor
Multitrait analysis of glaucoma identifies new risk loci and enables polygenic prediction of disease susceptibility and progression. Nature genetics 52 (2) (2020)
Qiao Fan, Alfred Pozarickij, Nicholas Y Q Tan, Xiaobo Guo, Virginie J M Verhoeven, Veronique Vitart, Jeremy A Guggenheim, Masahiro Miyake, J Willem L Tideman, Anthony P Khawaja, Liang Zhang, Stuart Macgregor, René Höhn, Peng Chen, Ginevra Biino, Juho Wedenoja, Seyed Ehsan Saffari, Milly S Tedja, Jing Xie, Carla Costa Lança, Ya-Xing Wang, Srujana Sahebjada, Johanna Mazur, Alireza Mirshahi, Nicholas G Martin, Seyhan Yazar, Craig E Pennell, Maurice K H Yap, Annechien E G Haarman, Clair A Enthoven, JanRoelof Polling, null null, null null, Alex W Hewitt, Vincent W V Jaddoe, Cornelia M van Duijn, Caroline Hayward, Ozren Polasek, E-Shyong Tai, Hosoda Yoshikatsu, Pirro G Hysi, Terri L Young, Akitaka Tsujikawa, Jie Jing Wang, Paul Mitchell, Norbert Pfeiffer, Olavi Pärssinen, Paul J Foster, Maurizio Fossarello, Shea Ping Yip, Cathy Williams, Christopher J Hammond, Jost Bruno Jonas, Mingguang He, David A Mackey, Tien-Yin Wong, Caroline C W Klaver, Seang-Mei Saw, Paul N Baird, Ching-Yu Cheng
Genome-wide association meta-analysis of corneal curvature identifies novel loci and shared genetic influences across axial length and refractive error. Communications biology 3 (1) (2020)
Ekaterina Yonova-Doing, Wanting Zhao, Robert P Igo, Chaolong Wang, Periasamy Sundaresan, Kristine E Lee, Gyungah R Jun, Alexessander Couto Alves, Xiaoran Chai, Anita Sook Yee Chan, Mei Chin Lee, Allan Fong, Ava G Tan, Chiea Chuen Khor, Emily Y Chew, Pirro G Hysi, Qiao Fan, Jacqueline Chua, Jaeyoon Chung, Jiemin Liao, Johanna M Colijn, Kathryn P Burdon, Lars G Fritsche, Maria K Swift, Maryam H Hilmy, Miao Ling Chee, Milly Tedja, Pieter W M Bonnemaijer, Preeti Gupta, Queenie S Tan, Zheng Li, Eranga N Vithana, Ravilla D Ravindran, Soon-Phaik Chee, Yuan Shi, Wenting Liu, Xinyi Su, Xueling S Sim, Yang Shen, Ya Xing Wang, Hengtong Li, Yih-Chung Tham, Yik Ying Teo, Tin Aung, Kerrin S Small, Paul Mitchell, Jost Bruno Jonas, Tien Yin Wong, Astrid E Fletcher, Caroline C W Klaver, Barbara E K Klein, Jie Jin Wang, Sudha K Iyengar, Christopher J Hammond, Ching-Yu Cheng
Common variants in SOX-2 and congenital cataract genes contribute to age-related nuclear cataract. Communications biology 3 (1) (2020)
Helene Choquet, Ronald B Melles, Jie Yin, Thomas J Hoffmann, Khanh K Thai, Mark N Kvale, Yambazi Banda, Alison J Hardcastle, Stephen J Tuft, M Maria Glymour, Catherine Schaefer, Neil Risch, K Saidas Nair, Pirro G Hysi, Eric Jorgensen
A multiethnic genome-wide analysis of 44,039 individuals identifies 41 new loci associated with central corneal thickness. Communications biology 3 (1) (2020)
Pirro G Hysi, Helene Choquet, Anthony P Khawaja, Robert Wojciechowski, Milly S Tedja, Jie Yin, Mark J Simcoe, Karina Patasova, Omar A Mahroo, Khanh K Thai, Phillippa M Cumberland, Ronald B Melles, Virginie J M Verhoeven, Veronique Vitart, Ayellet Segre, Richard A Stone, Nick Wareham, Alex W Hewitt, David A Mackey, Caroline C W Klaver, Stuart Macgregor, null null, Peng Tee Khaw, Paul J Foster, null null, Jeremy A Guggenheim, null null, Jugnoo S Rahi, Eric Jorgensen, Christopher J Hammond
Meta-analysis of 542,934 subjects of European ancestry identifies new genes and mechanisms predisposing to refractive error and myopia. Nature genetics 52 (4) (2020)
Adriana I Iglesias, Aniket Mishra, Veronique Vitart, Yelena Bykhovskaya, René Höhn, Henriët Springelkamp, Gabriel Cuellar-Partida, Puya Gharahkhani, Jessica N Cooke Bailey, Colin E Willoughby, Xiaohui Li, Seyhan Yazar, Abhishek Nag, Anthony P Khawaja, Ozren Polašek, David Siscovick, Paul Mitchell, Yih Chung Tham, Jonathan L Haines, Lisa S Kearns, Caroline Hayward, Yuan Shi, Elisabeth M van Leeuwen, Kent D Taylor, null null, Pieter W M Bonnemaijer, Jerome I Rotter, Nicholas G Martin, Tanja Zeller, Richard A Mills, Emmanuelle Souzeau, Sandra E Staffieri, Jost Bruno Jonas, Irene Schmidtmann, Thibaud Boutin, Jae Hee Kang, Sionne E M Lucas, Tien Yin Wong, Manfred E Beutel, James F Wilson, null null, null null, André G Uitterlinden, Eranga N Vithana, Paul J Foster, Pirro G Hysi, Alex W Hewitt, Chiea Chuen Khor, Louis R Pasquale, Grant W Montgomery, Caroline C W Klaver, Tin Aung, Norbert Pfeiffer, David A Mackey, Christopher J Hammond, Ching-Yu Cheng, Jamie E Craig, Yaron S Rabinowitz, Janey L Wiggs, Kathryn P Burdon, Cornelia M van Duijn, Stuart Macgregor
Author Correction: Cross-ancestry genome-wide association analysis of corneal thickness strengthens link between complex and Mendelian eye diseases. Nature communications 10 (1) (2019)
Alfred Pozarickij, Cathy Williams, Pirro G Hysi, Jeremy A Guggenheim, null null
Quantile regression analysis reveals widespread evidence for gene-environment or gene-gene interactions in myopia development. Communications biology 2 (2019)
Pieter W M Bonnemaijer, Elisabeth M van Leeuwen, Adriana I Iglesias, Puya Gharahkhani, Veronique Vitart, Anthony P Khawaja, Mark J Simcoe, René Höhn, Angela J Cree, Rob P Igo, null null, null null, null null, Aslihan Gerhold-Ay, Stefan Nickels, James F Wilson, Caroline Hayward, Thibaud S Boutin, Ozren Polašek, Tin Aung, Chiea Chuen Khor, Najaf Amin, Andrew John Lotery, Janey L Wiggs, Ching-Yu Cheng, Pirro G Hysi, Christopher J Hammond, Alberta A H J Thiadens, Stuart Macgregor, Caroline C W Klaver, Cornelia M van Duijn
Multi-trait genome-wide association study identifies new loci associated with optic disc parameters. Communications biology 2 (2019)
Christopher G Bell, Fei Gao, Wei Yuan, Leonie Roos, Richard James Acton, Yudong Xia, Jordana Bell, Kirsten Ward, Massimo Mangino, Pirro G Hysi, Jun Wang, Timothy D Spector
Obligatory and facilitative allelic variation in the DNA methylome within common disease-associated loci. Nature communications 9 (1) (2018)
Alessia Visconti, David L Duffy, Fan Liu, Gu Zhu, Wenting Wu, Yan Chen, Pirro G Hysi, Changqing Zeng, Marianna Sanna, Mark M Iles, Peter A Kanetsky, Florence Demenais, Merel A Hamer, Andre G Uitterlinden, Mohammad Arfan Ikram, Tamar Nijsten, Nicholas G Martin, Manfred Kayser, Tim D Spector, Jiali Han, Veronique Bataille, Mario Falchi
Genome-wide association study in 176,678 Europeans reveals genetic loci for tanning response to sun exposure. Nature communications 9 (1) (2018)
Milly S Tedja, Robert Wojciechowski, Pirro G Hysi, Nicholas Eriksson, Nicholas A Furlotte, Virginie J M Verhoeven, Adriana I Iglesias, Magda A Meester-Smoor, Stuart W J Tompson, Qiao Fan, Anthony P Khawaja, Ching-Yu Cheng, René Höhn, Kenji Yamashiro, Adam Wenocur, Clare Grazal, Toomas Haller, Andres Metspalu, Juho Wedenoja, Jost Bruno Jonas, Ya-Xing Wang, Jing Xie, Paul Mitchell, Paul J Foster, Barbara E K Klein, Ronald Klein, Andrew D Paterson, S Mohsen Hosseini, Rupal L Shah, Cathy Williams, Yik Ying Teo, Yih Chung Tham, Preeti Gupta, Wanting Zhao, Yuan Shi, Woei-Yuh Saw, E-Shyong Tai, Xue Ling Sim, Jennifer E Huffman, Ozren Polašek, Caroline Hayward, Goran Bencic, Igor Rudan, James F Wilson, null null, null null, null null, Peter K Joshi, Akitaka Tsujikawa, Fumihiko Matsuda, Kristina N Whisenhunt, Tanja Zeller, Peter J van der Spek, Roxanna Haak, Hanne Meijers-Heijboer, Elisabeth M van Leeuwen, Sudha K Iyengar, Jonathan H Lass, Albert Hofman, Fernando Rivadeneira, André G Uitterlinden, Johannes R Vingerling, Terho Lehtimäki, Olli T Raitakari, Ginevra Biino, Maria Pina Concas, Tae-Hwi Schwantes-An, Robert P Igo, Gabriel Cuellar-Partida, Nicholas G Martin, Jamie E Craig, Puya Gharahkhani, Katie M Williams, Abhishek Nag, Jugnoo S Rahi, Phillippa M Cumberland, Cécile Delcourt, Celine Bellenguez, Janina S Ried, Arthur A Bergen, Thomas Meitinger, Christian Gieger, Tien Yin Wong, Alex W Hewitt, David A Mackey, Claire L Simpson, Norbert Pfeiffer, Olavi Pärssinen, Paul N Baird, Veronique Vitart, Najaf Amin, Cornelia M van Duijn, Richard K Wilson, Terri L Young, Seang-Mei Saw, Dwight Stambolian, Stuart MacGregor, Jeremy A Guggenheim, Joyce Y Tung, Christopher J Hammond, Caroline C W Klaver
Genome-wide association meta-analysis highlights light-induced signaling as a driver for refractive error. Nature genetics 50 (6) (2018)
Markus A de Jong, Pirro G Hysi, Tim Spector, Wiro Niessen, Maarten J Koudstaal, Eppo B Wolvius, Manfred Kayser, Stefan Böhringer
Ensemble landmarking of 3D facial surface scans. Scientific reports 8 (1) (2018)
Adriana I Iglesias, Aniket Mishra, Veronique Vitart, Yelena Bykhovskaya, René Höhn, Henriët Springelkamp, Gabriel Cuellar-Partida, Puya Gharahkhani, Jessica N Cooke Bailey, Colin E Willoughby, Xiaohui Li, Seyhan Yazar, Abhishek Nag, Anthony P Khawaja, Ozren Polašek, David Siscovick, Paul Mitchell, Yih Chung Tham, Jonathan L Haines, Lisa S Kearns, Caroline Hayward, Yuan Shi, Elisabeth M van Leeuwen, Kent D Taylor, null null, Pieter W M Bonnemaijer, Jerome I Rotter, Nicholas G Martin, Tanja Zeller, Richard A Mills, Emmanuelle Souzeau, Sandra E Staffieri, Jost Bruno Jonas, Irene Schmidtmann, Thibaud Boutin, Jae Hee Kang, Sionne E M Lucas, Tien Yin Wong, Manfred E Beutel, James F Wilson, null null, null null, André G Uitterlinden, Eranga N Vithana, Paul J Foster, Pirro G Hysi, Alex W Hewitt, Chiea Chuen Khor, Louis R Pasquale, Grant W Montgomery, Caroline C W Klaver, Tin Aung, Norbert Pfeiffer, David A Mackey, Christopher J Hammond, Ching-Yu Cheng, Jamie E Craig, Yaron S Rabinowitz, Janey L Wiggs, Kathryn P Burdon, Cornelia M van Duijn, Stuart Macgregor
Cross-ancestry genome-wide association analysis of corneal thickness strengthens link between complex and Mendelian eye diseases. Nature communications 9 (1) (2018)
Anthony P Khawaja, Jessica N Cooke Bailey, Nicholas J Wareham, Robert A Scott, Mark J Simcoe, Robert P Igo, Yeunjoo E Song, Robert Wojciechowski, Ching-Yu Cheng, Peng T Khaw, Louis R Pasquale, Jonathan L Haines, Paul J Foster, Janey L Wiggs, Christopher J Hammond, Pirro G Hysi, null null, null null
Genome-wide analyses identify 68 new loci associated with intraocular pressure and improve risk prediction for primary open-angle glaucoma. Nature genetics 50 (6) (2018)
Pirro G Hysi, Ana M Valdes, Fan Liu, Nicholas A Furlotte, David M Evans, Veronique Bataille, Alessia Visconti, Gibran Hemani, George McMahon, Susan M Ring, George Davey Smith, David L Duffy, Gu Zhu, Scott D Gordon, Sarah E Medland, Bochao D Lin, Gonneke Willemsen, Jouke Jan Hottenga, Dragana Vuckovic, Giorgia Girotto, Ilaria Gandin, Cinzia Sala, Maria Pina Concas, Marco Brumat, Paolo Gasparini, Daniela Toniolo, Massimiliano Cocca, Antonietta Robino, Seyhan Yazar, Alex W Hewitt, Yan Chen, Changqing Zeng, Andre G Uitterlinden, Mohammad Arfan Ikram, Merel A Hamer, Cornelia M van Duijn, Tamar Nijsten, David A Mackey, Mario Falchi, Dorret I Boomsma, Nicholas G Martin, null null, David A Hinds, Manfred Kayser, Timothy D Spector
Genome-wide association meta-analysis of individuals of European ancestry identifies new loci explaining a substantial fraction of hair color variation and heritability. Nature genetics 50 (5) (2018)