Michael J Emanuele

ORCID

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 13

Top Venues

Nature communications

The EMBO journal

Nature structural & molecular biology

eLife

This page only lists publications with an associated author ORCID identifier.

Publications

Xiuxiu Lu, Monika Chandravanshi, Venkata R Sabbasani, Snehal Gaikwad, V Keith Hughitt, Nana Gyabaah-Kessie, Bradley T Scroggins, Sudipto Das, Wazo Myint, Michelle E Clapp, Charles D Schwieters, Marzena A Dyba, Derek L Bolhuis, Janusz W Koscielniak, Thorkell Andresson, Michael J Emanuele, Nicholas G Brown, Hiroshi Matsuo, Raj Chari, Deborah E Citrin, Beverly A Mock, Rolf E Swenson, Kylie J Walters
A structure-based designed small molecule depletes hRpn13 Pru and a select group of KEN box proteins. Nature communications 15 (1) (2024)
Xiuxiu Lu, Monika Chandravanshi, Venkata R Sabbasani, Snehal Gaikwad, V Keith Hughitt, Nana Gyabaah-Kessie, Bradley T Scroggins, Sudipto Das, Wazo Myint, Michelle E Clapp, Charles D Schwieters, Marzena A Dyba, Derek L Bolhuis, Janusz W Koscielniak, Thorkell Andresson, Michael J Emanuele, Nicholas G Brown, Hiroshi Matsuo, Raj Chari, Deborah E Citrin, Beverly A Mock, Rolf E Swenson, Kylie J Walters
A structure-based designed small molecule depletes hRpn13 Pru and a select group of KEN box proteins. Nature communications 15 (1) (2024)
Xiuxiu Lu, Monika Chandravanshi, Venkata R Sabbasani, Snehal Gaikwad, V Keith Hughitt, Nana Gyabaah-Kessie, Bradley T Scroggins, Sudipto Das, Wazo Myint, Michelle E Clapp, Charles D Schwieters, Marzena A Dyba, Derek L Bolhuis, Janusz W Koscielniak, Thorkell Andresson, Michael J Emanuele, Nicholas G Brown, Hiroshi Matsuo, Raj Chari, Deborah E Citrin, Beverly A Mock, Rolf E Swenson, Kylie J Walters
A structure-based designed small molecule depletes hRpn13 Pru and a select group of KEN box proteins. Nature communications 15 (1) (2024)
Xiuxiu Lu, Monika Chandravanshi, Venkata R Sabbasani, Snehal Gaikwad, V Keith Hughitt, Nana Gyabaah-Kessie, Bradley T Scroggins, Sudipto Das, Wazo Myint, Michelle E Clapp, Charles D Schwieters, Marzena A Dyba, Derek L Bolhuis, Janusz W Koscielniak, Thorkell Andresson, Michael J Emanuele, Nicholas G Brown, Hiroshi Matsuo, Raj Chari, Deborah E Citrin, Beverly A Mock, Rolf E Swenson, Kylie J Walters
A structure-based designed small molecule depletes hRpn13 Pru and a select group of KEN box proteins. Nature communications 15 (1) (2024)
Xiuxiu Lu, Monika Chandravanshi, Venkata R Sabbasani, Snehal Gaikwad, V Keith Hughitt, Nana Gyabaah-Kessie, Bradley T Scroggins, Sudipto Das, Wazo Myint, Michelle E Clapp, Charles D Schwieters, Marzena A Dyba, Derek L Bolhuis, Janusz W Koscielniak, Thorkell Andresson, Michael J Emanuele, Nicholas G Brown, Hiroshi Matsuo, Raj Chari, Deborah E Citrin, Beverly A Mock, Rolf E Swenson, Kylie J Walters
A structure-based designed small molecule depletes hRpn13 Pru and a select group of KEN box proteins. Nature communications 15 (1) (2024)
Xiuxiu Lu, Monika Chandravanshi, Venkata R Sabbasani, Snehal Gaikwad, V Keith Hughitt, Nana Gyabaah-Kessie, Bradley T Scroggins, Sudipto Das, Wazo Myint, Michelle E Clapp, Charles D Schwieters, Marzena A Dyba, Derek L Bolhuis, Janusz W Koscielniak, Thorkell Andresson, Michael J Emanuele, Nicholas G Brown, Hiroshi Matsuo, Raj Chari, Deborah E Citrin, Beverly A Mock, Rolf E Swenson, Kylie J Walters
A structure-based designed small molecule depletes hRpn13 Pru and a select group of KEN box proteins. Nature communications 15 (1) (2024)
Tatyana Bodrug, Kaeli A Welsh, Derek L Bolhuis, Ethan Paulаkonis, Raquel C Martinez-Chacin, Bei Liu, Nicholas Pinkin, Thomas Bonacci, Liying Cui, Pengning Xu, Olivia Roscow, Sascha Josef Amann, Irina Grishkovskaya, Michael J Emanuele, Joseph S Harrison, Joshua P Steimel, Klaus M Hahn, Wei Zhang, Ellen D Zhong, David Haselbach, Nicholas G Brown
Time-resolved cryo-EM (TR-EM) analysis of substrate polyubiquitination by the RING E3 anaphase-promoting complex/cyclosome (APC/C). Nature structural & molecular biology (2023)
Christine A Mills, Xianxi Wang, Dhaval P Bhatt, Paul A Grimsrud, Jacob Peter Matson, Debojyoti Lahiri, Daniel J Burke, Jeanette Gowen Cook, Matthew D Hirschey, Michael J Emanuele
Sirtuin 5 Is Regulated by the SCFCyclin F Ubiquitin Ligase and Is Involved in Cell Cycle Control. Molecular and cellular biology 41 (2) (2021)
Taylor P Enrico, Wayne Stallaert, Elizaveta T Wick, Peter Ngoi, Xianxi Wang, Seth M Rubin, Nicholas G Brown, Jeremy E Purvis, Michael J Emanuele
Cyclin F drives proliferation through SCF-dependent degradation of the retinoblastoma-like tumor suppressor p130/RBL2. eLife 10 (2021)
Kaeli A Welsh, Derek L Bolhuis, Anneroos E Nederstigt, Joshua Boyer, Brenda R S Temple, Thomas Bonacci, Li Gu, Alban Ordureau, J Wade Harper, Joshua P Steimel, Qi Zhang, Michael J Emanuele, Joseph S Harrison, Nicholas G Brown
Functional conservation and divergence of the helix-turn-helix motif of E2 ubiquitin-conjugating enzymes. The EMBO journal 41 (3) (2021)
Jennifer L Franks, Raquel C Martinez-Chacin, Xianxi Wang, Rochelle L Tiedemann, Thomas Bonacci, Rajarshi Choudhury, Derek L Bolhuis, Taylor P Enrico, Ryan D Mouery, Jeffrey S Damrauer, Feng Yan, Joseph S Harrison, M Ben Major, Katherine A Hoadley, Aussie Suzuki, Scott B Rothbart, Nicholas G Brown, Michael J Emanuele
In silico APC/C substrate discovery reveals cell cycle-dependent degradation of UHRF1 and other chromatin regulators. PLoS biology 18 (12) (2020)
Raquel C Martinez-Chacin, Tatyana Bodrug, Derek L Bolhuis, Katarzyna M Kedziora, Thomas Bonacci, Alban Ordureau, Morgan E Gibbs, Florian Weissmann, Renping Qiao, Gavin D Grant, Jeanette Gowen Cook, Jan-Michael Peters, J Wade Harper, Michael J Emanuele, Nicholas G Brown
Ubiquitin chain-elongating enzyme UBE2S activates the RING E3 ligase APC/C for substrate priming. Nature structural & molecular biology 27 (6) (2020)
Thomas Bonacci, Aussie Suzuki, Gavin D Grant, Natalie Stanley, Jeanette G Cook, Nicholas G Brown, Michael J Emanuele
Cezanne/OTUD7B is a cell cycle-regulated deubiquitinase that antagonizes the degradation of APC/C substrates. The EMBO journal 37 (16) (2018)

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Publication Activity (10 Years)

Top Topics

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Michael J Emanuele