Scott L Friedman (S Friedman)

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 37

Top Topics

Induced Pluripotent Stem Cells

Top Venues

Hepatology (Baltimore, Md.)

Science translational medicine

Nature metabolism

Scientific reports

This page only lists publications with an associated author ORCID identifier.

Publications

Michele Vacca, Ioannis Kamzolas, Lea Mørch Harder, Fiona Oakley, Christian Trautwein, Maximilian Hatting, Trenton Ross, Barbara Bernardo, Anouk Oldenburger, Sara Toftegaard Hjuler, Iwona Ksiazek, Daniel Lindén, Detlef Schuppan, Sergio Rodriguez-Cuenca, Maria Manuela Tonini, Tamara R Castañeda, Aimo Kannt, Cecília Maria Pereira Rodrigues, Simon Cockell, Olivier Govaere, Ann K Daly, Michael E D Allison, Kristian Honnens de Lichtenberg, Yong Ook Kim, Anna Lindblom, Stephanie Oldham, Anne-Christine Andréasson, Franklin J Schlerman, Jonathon Marioneaux, Arun Sanyal, Marta B Afonso, Ramy Younes, Yuichiro Amano, Scott L Friedman, Shuang Wang, Dipankar Bhattacharya, Eric Simon, Valérie Paradis, Alastair Burt, Ioanna-Maria Grypari, Susan Davies, Ann Driessen, Hiroaki Yashiro, Susanne Pors, Maja Worm Andersen, Michael Feigh, Carla Yunis, Pierre Bedossa, Michelle Stewart, Heather L Cater, Sara E Wells, Jörn Markus Schattenberg, Quentin Mark Anstee, null null, Dina Tiniakos, James W Perfield, Evangelia Petsalaki, Peter Davidsen, Antonio Vidal-Puig
An unbiased ranking of murine dietary models based on their proximity to human metabolic dysfunction-associated steatotic liver disease (MASLD). Nature metabolism 6 (6) (2024)
James K Carter, Ming-Chao Tsai, Nicholas J Venturini, Jiangting Hu, John J Lemasters, Miguel Torres Martin, Daniela Sia, Shuang Wang, Youngmin A Lee, Scott L Friedman
Stellate cell-specific adhesion molecule protocadherin 7 regulates sinusoidal contraction. Hepatology (Baltimore, Md.) 80 (3) (2024)
Michele Vacca, Ioannis Kamzolas, Lea Mørch Harder, Fiona Oakley, Christian Trautwein, Maximilian Hatting, Trenton Ross, Barbara Bernardo, Anouk Oldenburger, Sara Toftegaard Hjuler, Iwona Ksiazek, Daniel Lindén, Detlef Schuppan, Sergio Rodriguez-Cuenca, Maria Manuela Tonini, Tamara R Castañeda, Aimo Kannt, Cecília Maria Pereira Rodrigues, Simon Cockell, Olivier Govaere, Ann K Daly, Michael E D Allison, Kristian Honnens de Lichtenberg, Yong Ook Kim, Anna Lindblom, Stephanie Oldham, Anne-Christine Andréasson, Franklin J Schlerman, Jonathon Marioneaux, Arun Sanyal, Marta B Afonso, Ramy Younes, Yuichiro Amano, Scott L Friedman, Shuang Wang, Dipankar Bhattacharya, Eric Simon, Valérie Paradis, Alastair Burt, Ioanna-Maria Grypari, Susan Davies, Ann Driessen, Hiroaki Yashiro, Susanne Pors, Maja Worm Andersen, Michael Feigh, Carla Yunis, Pierre Bedossa, Michelle Stewart, Heather L Cater, Sara E Wells, Jörn Markus Schattenberg, Quentin Mark Anstee, null null, Dina Tiniakos, James W Perfield, Evangelia Petsalaki, Peter Davidsen, Antonio Vidal-Puig
An unbiased ranking of murine dietary models based on their proximity to human metabolic dysfunction-associated steatotic liver disease (MASLD). Nature metabolism 6 (6) (2024)
James K Carter, Ming-Chao Tsai, Nicholas J Venturini, Jiangting Hu, John J Lemasters, Miguel Torres Martin, Daniela Sia, Shuang Wang, Youngmin A Lee, Scott L Friedman
Stellate cell-specific adhesion molecule protocadherin 7 regulates sinusoidal contraction. Hepatology (Baltimore, Md.) 80 (3) (2024)
John G Hong, Yvette Carbajal, Joshaya Trotman, Mariel Glass, Victoria Sclar, Isaac L Alter, Peng Zhang, Liheng Wang, Li Chen, Matthieu Petitjean, Scott L Friedman, Charles DeRossi, Jaime Chu
Mannose Supplementation Curbs Liver Steatosis and Fibrosis in Murine MASH by Inhibiting Fructose Metabolism. bioRxiv : the preprint server for biology (2024)
Michele Vacca, Ioannis Kamzolas, Lea Mørch Harder, Fiona Oakley, Christian Trautwein, Maximilian Hatting, Trenton Ross, Barbara Bernardo, Anouk Oldenburger, Sara Toftegaard Hjuler, Iwona Ksiazek, Daniel Lindén, Detlef Schuppan, Sergio Rodriguez-Cuenca, Maria Manuela Tonini, Tamara R Castañeda, Aimo Kannt, Cecília Maria Pereira Rodrigues, Simon Cockell, Olivier Govaere, Ann K Daly, Michael E D Allison, Kristian Honnens de Lichtenberg, Yong Ook Kim, Anna Lindblom, Stephanie Oldham, Anne-Christine Andréasson, Franklin J Schlerman, Jonathon Marioneaux, Arun Sanyal, Marta B Afonso, Ramy Younes, Yuichiro Amano, Scott L Friedman, Shuang Wang, Dipankar Bhattacharya, Eric Simon, Valérie Paradis, Alastair Burt, Ioanna-Maria Grypari, Susan Davies, Ann Driessen, Hiroaki Yashiro, Susanne Pors, Maja Worm Andersen, Michael Feigh, Carla Yunis, Pierre Bedossa, Michelle Stewart, Heather L Cater, Sara E Wells, Jörn Markus Schattenberg, Quentin Mark Anstee, null null, Dina Tiniakos, James W Perfield, Evangelia Petsalaki, Peter Davidsen, Antonio Vidal-Puig
An unbiased ranking of murine dietary models based on their proximity to human metabolic dysfunction-associated steatotic liver disease (MASLD). Nature metabolism (2024)
Corina Amor, Judith Feucht, Josef Leibold, Yu-Jui Ho, Changyu Zhu, Direna Alonso-Curbelo, Jorge Mansilla-Soto, Jacob A Boyer, Xiang Li, Theodoros Giavridis, Amanda Kulick, Shauna Houlihan, Ellinor Peerschke, Scott L Friedman, Vladimir Ponomarev, Alessandra Piersigilli, Michel Sadelain, Scott W Lowe
Author Correction: Senolytic CAR T cells reverse senescence-associated pathologies. Nature (2024)
Michele Vacca, Ioannis Kamzolas, Lea Mørch Harder, Fiona Oakley, Christian Trautwein, Maximilian Hatting, Trenton Ross, Barbara Bernardo, Anouk Oldenburger, Sara Toftegaard Hjuler, Iwona Ksiazek, Daniel Lindén, Detlef Schuppan, Sergio Rodriguez-Cuenca, Maria Manuela Tonini, Tamara R Castañeda, Aimo Kannt, Cecília Maria Pereira Rodrigues, Simon Cockell, Olivier Govaere, Ann K Daly, Michael E D Allison, Kristian Honnens de Lichtenberg, Yong Ook Kim, Anna Lindblom, Stephanie Oldham, Anne-Christine Andréasson, Franklin J Schlerman, Jonathon Marioneaux, Arun Sanyal, Marta B Afonso, Ramy Younes, Yuichiro Amano, Scott L Friedman, Shuang Wang, Dipankar Bhattacharya, Eric Simon, Valérie Paradis, Alastair Burt, Ioanna-Maria Grypari, Susan Davies, Ann Driessen, Hiroaki Yashiro, Susanne Pors, Maja Worm Andersen, Michael Feigh, Carla Yunis, Pierre Bedossa, Michelle Stewart, Heather L Cater, Sara E Wells, Jörn Markus Schattenberg, Quentin Mark Anstee, null null, Dina Tiniakos, James W Perfield, Evangelia Petsalaki, Peter Davidsen, Antonio Vidal-Puig
An unbiased ranking of murine dietary models based on their proximity to human metabolic dysfunction-associated steatotic liver disease (MASLD). Nature metabolism 6 (6) (2024)
Vlad Ratziu, Yusuf Yilmaz, Don Lazas, Scott L Friedman, Caroline Lackner, Cynthia Behling, Oscar W Cummings, Li Chen, Mathieu Petitjean, Yossi Gilgun-Sherki, Tali Gorfine, Shaul Kadosh, Eli Eyal, Arun J Sanyal
Aramchol improves hepatic fibrosis in metabolic dysfunction-associated steatohepatitis: Results of multimodality assessment using both conventional and digital pathology. Hepatology (Baltimore, Md.) (2024)
James K Carter, Ming-Chao Tsai, Nicholas J Venturini, Jiangting Hu, John J Lemasters, Miguel Torres Martin, Daniela Sia, Shuang Wang, Youngmin A Lee, Scott L Friedman
Stellate cell-specific adhesion molecule protocadherin 7 regulates sinusoidal contraction. Hepatology (Baltimore, Md.) (2024)
Michele Vacca, Ioannis Kamzolas, Lea Mørch Harder, Fiona Oakley, Christian Trautwein, Maximilian Hatting, Trenton Ross, Barbara Bernardo, Anouk Oldenburger, Sara Toftegaard Hjuler, Iwona Ksiazek, Daniel Lindén, Detlef Schuppan, Sergio Rodriguez-Cuenca, Maria Manuela Tonini, Tamara R Castañeda, Aimo Kannt, Cecília Maria Pereira Rodrigues, Simon Cockell, Olivier Govaere, Ann K Daly, Michael E D Allison, Kristian Honnens de Lichtenberg, Yong Ook Kim, Anna Lindblom, Stephanie Oldham, Anne-Christine Andréasson, Franklin J Schlerman, Jonathon Marioneaux, Arun Sanyal, Marta B Afonso, Ramy Younes, Yuichiro Amano, Scott L Friedman, Shuang Wang, Dipankar Bhattacharya, Eric Simon, Valérie Paradis, Alastair Burt, Ioanna-Maria Grypari, Susan Davies, Ann Driessen, Hiroaki Yashiro, Susanne Pors, Maja Worm Andersen, Michael Feigh, Carla Yunis, Pierre Bedossa, Michelle Stewart, Heather L Cater, Sara E Wells, Jörn Markus Schattenberg, Quentin Mark Anstee, null null, Dina Tiniakos, James W Perfield, Evangelia Petsalaki, Peter Davidsen, Antonio Vidal-Puig
An unbiased ranking of murine dietary models based on their proximity to human metabolic dysfunction-associated steatotic liver disease (MASLD). Nature metabolism (2024)
Shuang Wang, Kenneth Li, Eliana Pickholz, Ross Dobie, Kylie P Matchett, Neil Cowan Henderson, Chris Carrico, Ian Driver, Martin Borch Jensen, Li Chen, Mathieu Petitjean, Dipankar Bhattacharya, Maria Isabel Fiel, Xiao Liu, Tatiana Kisseleva, Uri Alon, Miri Adler, Ruslan Medzhitov, Scott L Friedman
An autocrine signaling circuit in hepatic stellate cells underlies advanced fibrosis in nonalcoholic steatohepatitis. Science translational medicine 15 (677) (2023)
Shuang Wang, Kenneth Li, Eliana Pickholz, Ross Dobie, Kylie P Matchett, Neil Cowan Henderson, Chris Carrico, Ian Driver, Martin Borch Jensen, Li Chen, Mathieu Petitjean, Dipankar Bhattacharya, Maria Isabel Fiel, Xiao Liu, Tatiana Kisseleva, Uri Alon, Miri Adler, Ruslan Medzhitov, Scott L Friedman
An autocrine signaling circuit in hepatic stellate cells underlies advanced fibrosis in nonalcoholic steatohepatitis. Science translational medicine 15 (677) (2023)
Shuang Wang, Kenneth Li, Eliana Pickholz, Ross Dobie, Kylie P Matchett, Neil Cowan Henderson, Chris Carrico, Ian Driver, Martin Borch Jensen, Li Chen, Mathieu Petitjean, Dipankar Bhattacharya, Maria Isabel Fiel, Xiao Liu, Tatiana Kisseleva, Uri Alon, Miri Adler, Ruslan Medzhitov, Scott L Friedman
An autocrine signaling circuit in hepatic stellate cells underlies advanced fibrosis in nonalcoholic steatohepatitis. Science translational medicine 15 (677) (2023)
Vincent Quoc-Huy Trinh, Ting-Fang Lee, Sara Lemoinne, Kevin C Ray, Maria D Ybanez, Takuma Tsuchida, James K Carter, Judith Agudo, Brian D Brown, Kemal M Akat, Scott L Friedman, Youngmin A Lee
Hepatic stellate cells maintain liver homeostasis through paracrine neurotrophin-3 signaling that induces hepatocyte proliferation. Science signaling 16 (787) (2023)
Shuang Wang, Scott L Friedman
Found in translation-Fibrosis in metabolic dysfunction-associated steatohepatitis (MASH). Science translational medicine 15 (716) (2023)
Bruno Cogliati, Chittampalli N Yashaswini, Shuang Wang, Daniela Sia, Scott L Friedman
Friend or foe? The elusive role of hepatic stellate cells in liver cancer. Nature reviews. Gastroenterology & hepatology (2023)
Josep M Llovet, Catherine E Willoughby, Amit G Singal, Tim F Greten, Mathias Heikenwälder, Hashem E El-Serag, Richard S Finn, Scott L Friedman
Nonalcoholic steatohepatitis-related hepatocellular carcinoma: pathogenesis and treatment. Nature reviews. Gastroenterology & hepatology (2023)
Connor Quinn, Mario C Rico, Carmen Merali, Carlos A Barrero, Oscar Perez-Leal, Victoria Mischley, John Karanicolas, Scott L Friedman, Salim Merali
Secreted folate receptor γ drives fibrogenesis in metabolic dysfunction-associated steatohepatitis by amplifying TGFβ signaling in hepatic stellate cells. Science translational medicine 15 (715) (2023)
Miguel A Martin-Serrano, Benjamin Kepecs, Miguel Torres-Martin, Emily R Bramel, Philipp K Haber, Elliot Merritt, Alexander Rialdi, Nesteene Joy Param, Miho Maeda, Katherine E Lindblad, James K Carter, Marina Barcena-Varela, Vincenzo Mazzaferro, Myron Schwartz, Silvia Affo, Robert F Schwabe, Augusto Villanueva, Ernesto Guccione, Scott L Friedman, Amaia Lujambio, Anna Tocheva, Josep M Llovet, Swan N Thung, Alexander M Tsankov, Daniela Sia
Novel microenvironment-based classification of intrahepatic cholangiocarcinoma with therapeutic implications. Gut (2022)
Scott L Friedman, Massimo Pinzani
Hepatic fibrosis 2022: Unmet needs and a blueprint for the future. Hepatology (Baltimore, Md.) 75 (2) (2022)
Indrajit Nanda, Claus Steinlein, Thomas Haaf, Eva M Buhl, Dominik G Grimm, Scott L Friedman, Steffen K Meurer, Sarah K Schröder, Ralf Weiskirchen
Genetic Characterization of Rat Hepatic Stellate Cell Line HSC-T6 for In Vitro Cell Line Authentication. Cells 11 (11) (2022)
Carla Montironi, Florian Castet, Philipp K Haber, Roser Pinyol, Miguel Torres-Martin, Laura Torrens, Agavni Mesropian, Huan Wang, Marc Puigvehi, Miho Maeda, Wei Qiang Leow, Elizabeth Harrod, Patricia Taik, Jigjidsuren Chinburen, Erdenebileg Taivanbaatar, Enkhbold Chinbold, Manel Solé Arqués, Michael Donovan, Swan Thung, Jaclyn Neely, Vincenzo Mazzaferro, Jeffrey Anderson, Sasan Roayaie, Myron Schwartz, Augusto Villanueva, Scott L Friedman, Andrew Uzilov, Daniela Sia, Josep M Llovet
Inflamed and non-inflamed classes of HCC: a revised immunogenomic classification. Gut (2022)
Vlad Ratziu, L de Guevara, R Safadi, F Poordad, F Fuster, J Flores-Figueroa, M Arrese, Anna L Fracanzani, D Ben Bashat, K Lackner, T Gorfine, S Kadosh, R Oren, M Halperin, L Hayardeny, Stephen Caldwell, Scott L Friedman, null null, Arun J Sanyal
Aramchol in patients with nonalcoholic steatohepatitis: a randomized, double-blind, placebo-controlled phase 2b trial. Nature medicine 27 (10) (2021)
Hua Zhang, Yongyuan Ma, Xinying Cheng, Dong-Bo Wu, Xingming Huang, Bin Chen, Yafeng Ren, Wei Jiang, Xiaoqiang Tang, Ting Bai, Yutian Chen, Yilin Zhao, Chunxue Zhang, Xia Xiao, Jing Liu, Yue Deng, Tinghong Ye, Mei Chen, Han-Min Liu, Scott L Friedman, Liping Chen, Bi-Sen Ding, Zhongwei Cao
Targeting epigenetically maladapted vascular niche alleviates liver fibrosis in nonalcoholic steatohepatitis. Science translational medicine 13 (614) (2021)
Tsipora M Huisman, Douglas T Dieterich, Scott L Friedman
Experimental and Investigational Targeted Therapies for the Management of Fibrosis in NASH: An Update. Journal of experimental pharmacology 13 (2021)
Laura Torrens, Carla Montironi, Marc Puigvehí, Agavni Mesropian, Jack Leslie, Philipp K Haber, Miho Maeda, Ugne Balaseviciute, Catherine E Willoughby, Jordi Abril-Fornaguera, Marta Piqué-Gili, Miguel Torres-Martin, Judit Peix, Daniel Geh, Erik Ramon-Gil, Behnam Saberi, Scott L Friedman, Derek A Mann, Daniela Sia, Josep M Llovet
Immunomodulatory Effects of Lenvatinib Plus Anti-Programmed Cell Death Protein 1 in Mice and Rationale for Patient Enrichment in Hepatocellular Carcinoma. Hepatology (Baltimore, Md.) 74 (5) (2021)
Youngmin A Lee, Scott L Friedman
Inflammatory and fibrotic mechanisms in NAFLD-Implications for new treatment strategies. Journal of internal medicine (2021)
Corina Amor, Judith Feucht, Josef Leibold, Yu-Jui Ho, Changyu Zhu, Direna Alonso-Curbelo, Jorge Mansilla-Soto, Jacob A Boyer, Xiang Li, Theodoros Giavridis, Amanda Kulick, Shauna Houlihan, Ellinor Peerschke, Scott L Friedman, Vladimir Ponomarev, Alessandra Piersigilli, Michel Sadelain, Scott W Lowe
Senolytic CAR T cells reverse senescence-associated pathologies. Nature 583 (7814) (2020)
Gayane Hrachia Buniatian, Ralf Weiskirchen, Thomas S Weiss, Ute Schwinghammer, Martin Fritz, Torgom Seferyan, Barbara Proksch, Michael Glaser, Ali Lourhmati, Marine Buadze, Erawan Borkham-Kamphorst, Frank Gaunitz, Christoph H Gleiter, Thomas Lang, Elke Schaeffeler, Roman Tremmel, Holger Cynis, William H Frey, Rolf Gebhardt, Scott L Friedman, Wolfgang Mikulits, Matthias Schwab, Lusine Danielyan
Antifibrotic Effects of Amyloid-Beta and Its Loss in Cirrhotic Liver. Cells 9 (2) (2020)
Varinder S Athwal, James Pritchett, Katherine Martin, Jessica Llewellyn, Jennifer Scott, Emma Harvey, Abed M Zaitoun, Aoibheann F Mullan, Leo A H Zeef, Scott L Friedman, William L Irving, Neil A Hanley, Indra Neil Guha, Karen Piper Hanley
Publisher Correction: SOX9 regulated matrix proteins are increased in patients serum and correlate with severity of liver fibrosis. Scientific reports 9 (1) (2019)
Varinder S Athwal, James Pritchett, Katherine Martin, Jessica Llewellyn, Jennifer Scott, Emma Harvey, Abed M Zaitoun, Aoibheann F Mullan, Leo A H Zeef, Scott L Friedman, William L Irving, Neil A Hanley, Indra Neil Guha, Karen Piper Hanley
SOX9 regulated matrix proteins are increased in patients serum and correlate with severity of liver fibrosis. Scientific reports 8 (1) (2018)
Scott L Friedman, Brent A Neuschwander-Tetri, Mary Rinella, Arun J Sanyal
Mechanisms of NAFLD development and therapeutic strategies. Nature medicine 24 (7) (2018)
Youngmin A Lee, Luke A Noon, Kemal M Akat, Maria D Ybanez, Ting-Fang Lee, Marie-Luise Berres, Naoto Fujiwara, Nicolas Goossens, Hsin-I Chou, Fatemeh P Parvin-Nejad, Bilon Khambu, Elisabeth G M Kramer, Ronald Gordon, Cathie Pfleger, Doris Germain, Gareth R John, Kirk N Campbell, Zhenyu Yue, Xiao-Ming Yin, Ana Maria Cuervo, Mark J Czaja, M Isabel Fiel, Yujin Hoshida, Scott L Friedman
Autophagy is a gatekeeper of hepatic differentiation and carcinogenesis by controlling the degradation of Yap. Nature communications 9 (1) (2018)
Ismail Labgaa, Carlos Villacorta-Martin, Delia D'Avola, Amanda J Craig, Johann von Felden, Sebastiao N Martins-Filho, Daniela Sia, Ashley Stueck, Stephen C Ward, M Isabel Fiel, Milind Mahajan, Parissa Tabrizian, Swan N Thung, Celina Ang, Scott L Friedman, Josep M Llovet, Myron Schwartz, Augusto Villanueva
A pilot study of ultra-deep targeted sequencing of plasma DNA identifies driver mutations in hepatocellular carcinoma. Oncogene 37 (27) (2018)
Svenja Sydor, Paul Manka, Jan Best, Sami Jafoui, Jan-Peter Sowa, Miguel Eugenio Zoubek, Virginia Hernandez-Gea, Francisco Javier Cubero, Julia Kälsch, Diana Vetter, Maria Isabel Fiel, Yujin Hoshida, C Billie Bian, Leonard J Nelson, Han Moshage, Klaas Nico Faber, Andreas Paul, Hideo A Baba, Guido Gerken, Scott L Friedman, Ali Canbay, Lars P Bechmann
Krüppel-like factor 6 is a transcriptional activator of autophagy in acute liver injury. Scientific reports 7 (1) (2017)
Ruchi Bansal, Shigeki Nakagawa, Saleh Yazdani, Joop van Baarlen, Anu Venkatesh, Anna P Koh, Won-Min Song, Nicolas Goossens, Hideo Watanabe, Mary B Beasley, Charles A Powell, Gert Storm, Naftali Kaminski, Harry van Goor, Scott L Friedman, Yujin Hoshida, Jai Prakash
Integrin alpha 11 in the regulation of the myofibroblast phenotype: implications for fibrotic diseases. Experimental & molecular medicine 49 (11) (2017)