Shan Zha

ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 34

Top Venues

Nature structural & molecular biology

Science signaling

Proceedings of the National Academy of Sciences of the United States of America

bioRxiv : the preprint server for biology

Columbia University

Johns Hopkins Medical Institute (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Columbia University

United States

Associate Professor :: Pediatrics, Pathology and Cell Biology

Columbia University Dec 01 2009

United States

Assistant Professor :: Institute for Cancer Genetics

Children's Hostpital at Boston

United States

Instructor :: Molecular Cellular Immunology

Education History

Johns Hopkins Medical Institute

United States

PHD :: Pharmacology and Molecular Science

Peking University

China

BSC :: Medicine

Publications

Alexander J R Bishop, July Carolina Romero, Sonal Tonapi, Manish Parihar, Eva Loranc, Henry Miller, Liesl Lawrence, Nicklas Bassani, Daniel Robledo, Lin Cao, Jia Nie, Kairi Kanda, Aiola Stoja, Natalia Garcia, Aparna Gorthi, Brian Stoveken, Andrew N Lane, Teresa Fan, Teresa Cassel, Shan Zha, Nicolas Musi
ATM phosphorylation of CD98HC increases antiporter membrane localization and prevents chronic toxic glutamate accumulation in Ataxia telangiectasia. Research square (2024)
Xiaohui Lin, Kay Sze Karina Leung, Kaitlynn F Wolfe, Brian J Lee, Shan Zha
XRCC1 mediates PARP1- and PAR-dependent recruitment of PARP2 to DNA damage sites. bioRxiv : the preprint server for biology (2024)
Yuanyuan Li, Richa B Shah, Samanta Sarti, Alicia L Belcher, Brian J Lee, Andrej Gorbatenko, Francesca Nemati, Honglin Yu, Zoe Stanley, Mahbuba Rahman, Zhengping Shao, Jose M Silva, Shan Zha, Samuel Sidi
A noncanonical IRAK4-IRAK1 pathway counters DNA damage-induced apoptosis independently of TLR/IL-1R signaling. Science signaling 16 (816) (2023)
Yuanyuan Li, Richa B Shah, Samanta Sarti, Alicia L Belcher, Brian J Lee, Andrej Gorbatenko, Francesca Nemati, Honglin Yu, Zoe Stanley, Mahbuba Rahman, Zhengping Shao, Jose M Silva, Shan Zha, Samuel Sidi
A noncanonical IRAK4-IRAK1 pathway counters DNA damage-induced apoptosis independently of TLR/IL-1R signaling. Science signaling 16 (816) (2023)
Yuanyuan Li, Richa B Shah, Samanta Sarti, Alicia L Belcher, Brian J Lee, Andrej Gorbatenko, Francesca Nemati, Honglin Yu, Zoe Stanley, Mahbuba Rahman, Zhengping Shao, Jose M Silva, Shan Zha, Samuel Sidi
A noncanonical IRAK4-IRAK1 pathway counters DNA damage-induced apoptosis independently of TLR/IL-1R signaling. Science signaling 16 (816) (2023)
Yuanyuan Li, Richa B Shah, Samanta Sarti, Alicia L Belcher, Brian J Lee, Andrej Gorbatenko, Francesca Nemati, Ian Yu, Zoe Stanley, Zhengping Shao, Jose M Silva, Shan Zha, Samuel Sidi
A Non-Canonical IRAK Signaling Pathway Triggered by DNA Damage. bioRxiv : the preprint server for biology (2023)
Yuanyuan Li, Richa B Shah, Samanta Sarti, Alicia L Belcher, Brian J Lee, Andrej Gorbatenko, Francesca Nemati, Honglin Yu, Zoe Stanley, Mahbuba Rahman, Zhengping Shao, Jose M Silva, Shan Zha, Samuel Sidi
A noncanonical IRAK4-IRAK1 pathway counters DNA damage-induced apoptosis independently of TLR/IL-1R signaling. Science signaling 16 (816) (2023)
Yuanyuan Li, Richa B Shah, Samanta Sarti, Alicia L Belcher, Brian J Lee, Andrej Gorbatenko, Francesca Nemati, Honglin Yu, Zoe Stanley, Mahbuba Rahman, Zhengping Shao, Jose M Silva, Shan Zha, Samuel Sidi
A noncanonical IRAK4-IRAK1 pathway counters DNA damage-induced apoptosis independently of TLR/IL-1R signaling. Science signaling 16 (816) (2023)
Yimeng Zhu, Wenxia Jiang, Brian J Lee, Angelina Li, Steven Gershik, Shan Zha
Phosphorylation of DNA-PKcs at the S2056 cluster ensures efficient and productive lymphocyte development in XLF-deficient mice. Proceedings of the National Academy of Sciences of the United States of America 120 (25) (2023)
Marie-France Langelier, Xiaohui Lin, Shan Zha, John M Pascal
Clinical PARP inhibitors allosterically induce PARP2 retention on DNA. Science advances 9 (12) (2023)
Zhengping Shao, Brian J Lee, Hanwen Zhang, Xiaohui Lin, Chen Li, Wenxia Jiang, Napon Chirathivat, Steven Gershik, Michael M Shen, Richard Baer, Shan Zha
Inactive PARP1 causes embryonic lethality and genome instability in a dominant-negative manner. Proceedings of the National Academy of Sciences of the United States of America 120 (31) (2023)
Yuanyuan Li, Richa B Shah, Samanta Sarti, Alicia L Belcher, Brian J Lee, Andrej Gorbatenko, Francesca Nemati, Honglin Yu, Zoe Stanley, Mahbuba Rahman, Zhengping Shao, Jose M Silva, Shan Zha, Samuel Sidi
A noncanonical IRAK4-IRAK1 pathway counters DNA damage-induced apoptosis independently of TLR/IL-1R signaling. Science signaling 16 (816) (2023)
Demis Menolfi, Brian J Lee, Hanwen Zhang, Wenxia Jiang, Nicole E Bowen, Yunyue Wang, Junfei Zhao, Antony B Holmes, Steven Gershik, Raúl Rabadán, Baek Kim, Shan Zha
ATR kinase supports normal proliferation in the early S phase by preventing replication resource exhaustion. Nature communications 14 (1) (2023)
Yuanyuan Li, Richa B Shah, Samanta Sarti, Alicia L Belcher, Brian J Lee, Andrej Gorbatenko, Francesca Nemati, Ian Yu, Zoe Stanley, Zhengping Shao, Jose M Silva, Shan Zha, Samuel Sidi
A Non-Canonical IRAK Signaling Pathway Triggered by DNA Damage. bioRxiv : the preprint server for biology (2023)
Jennifer Zagelbaum, Allana Schooley, Junfei Zhao, Benjamin R Schrank, Elsa Callen, Shan Zha, Max E Gottesman, André Nussenzweig, Raúl Rabadán, Job Dekker, Jean Gautier
Author Correction: Multiscale reorganization of the genome following DNA damage facilitates chromosome translocations via nuclear actin polymerization. Nature structural & molecular biology (2023)
Xiaohui Lin, Wenxia Jiang, Johannes Rudolph, Brian J Lee, Karolin Luger, Shan Zha
PARP inhibitors trap PARP2 and alter the mode of recruitment of PARP2 at DNA damage sites. Nucleic acids research 50 (7) (2022)
Jennifer Zagelbaum, Allana Schooley, Junfei Zhao, Benjamin R Schrank, Elsa Callen, Shan Zha, Max E Gottesman, André Nussenzweig, Raúl Rabadán, Job Dekker, Jean Gautier
Multiscale reorganization of the genome following DNA damage facilitates chromosome translocations via nuclear actin polymerization. Nature structural & molecular biology (2022)
Jennifer Zagelbaum, Allana Schooley, Junfei Zhao, Benjamin R Schrank, Elsa Callen, Shan Zha, Max E Gottesman, André Nussenzweig, Raúl Rabadán, Job Dekker, Jean Gautier
Multiscale reorganization of the genome following DNA damage facilitates chromosome translocations via nuclear actin polymerization. Nature structural & molecular biology 30 (1) (2022)
Jennifer Zagelbaum, Allana Schooley, Junfei Zhao, Benjamin R Schrank, Elsa Callen, Shan Zha, Max E Gottesman, André Nussenzweig, Raúl Rabadán, Job Dekker, Jean Gautier
Multiscale reorganization of the genome following DNA damage facilitates chromosome translocations via nuclear actin polymerization. Nature structural & molecular biology 30 (1) (2022)
Jennifer Zagelbaum, Allana Schooley, Junfei Zhao, Benjamin R Schrank, Elsa Callen, Shan Zha, Max E Gottesman, André Nussenzweig, Raúl Rabadán, Job Dekker, Jean Gautier
Multiscale reorganization of the genome following DNA damage facilitates chromosome translocations via nuclear actin polymerization. Nature structural & molecular biology (2022)
Jennifer Zagelbaum, Allana Schooley, Junfei Zhao, Benjamin R Schrank, Elsa Callen, Shan Zha, Max E Gottesman, André Nussenzweig, Raúl Rabadán, Job Dekker, Jean Gautier
Multiscale reorganization of the genome following DNA damage facilitates chromosome translocations via nuclear actin polymerization. Nature structural & molecular biology 30 (1) (2022)
Jennifer Zagelbaum, Allana Schooley, Junfei Zhao, Benjamin R Schrank, Elsa Callen, Shan Zha, Max E Gottesman, André Nussenzweig, Raúl Rabadán, Job Dekker, Jean Gautier
Multiscale reorganization of the genome following DNA damage facilitates chromosome translocations via nuclear actin polymerization. Nature structural & molecular biology 30 (1) (2022)
Jennifer Zagelbaum, Allana Schooley, Junfei Zhao, Benjamin R Schrank, Elsa Callen, Shan Zha, Max E Gottesman, André Nussenzweig, Raúl Rabadán, Job Dekker, Jean Gautier
Multiscale reorganization of the genome following DNA damage facilitates chromosome translocations via nuclear actin polymerization. Nature structural & molecular biology 30 (1) (2022)
Demis Menolfi, Shan Zha
Targeting BRCA-mutated tumors in mitosis. Nature cancer 2 (12) (2022)
Jennifer Zagelbaum, Allana Schooley, Junfei Zhao, Benjamin R Schrank, Elsa Callen, Shan Zha, Max E Gottesman, André Nussenzweig, Raúl Rabadán, Job Dekker, Jean Gautier
Multiscale reorganization of the genome following DNA damage facilitates chromosome translocations via nuclear actin polymerization. Nature structural & molecular biology (2022)
Hanwen Zhang, Xiaohui Lin, Shan Zha
Revisiting PARP2 and PARP1 trapping through quantitative live-cell imaging. Biochemical Society transactions 50 (4) (2022)
Xiaobin S Wang, Demis Menolfi, Foon Wu-Baer, Marco Fangazio, Stefanie N Meyer, Zhengping Shao, Yunyue Wang, Yimeng Zhu, Brian J Lee, Verna M Estes, Olivia M Cupo, Jean Gautier, Laura Pasqualucci, Riccardo Dalla-Favera, Richard Baer, Shan Zha
DNA damage-induced phosphorylation of CtIP at a conserved ATM/ATR site T855 promotes lymphomagenesis in mice. Proceedings of the National Academy of Sciences of the United States of America 118 (38) (2021)
Maja Milanovic, Zhengping Shao, Verna M Estes, Xiaobin S Wang, Demis Menolfi, Xiaohui Lin, Brian J Lee, Jun Xu, Olivia M Cupo, Dong Wang, Shan Zha
FATC Domain Deletion Compromises ATM Protein Stability, Blocks Lymphocyte Development, and Promotes Lymphomagenesis. Journal of immunology (Baltimore, Md. : 1950) 206 (6) (2021)
Demis Menolfi, Shan Zha
ATM, ATR and DNA-PKcs kinases-the lessons from the mouse models: inhibition ≠ deletion. Cell & bioscience 10 (2020)
Jennifer L Crowe, Xiaobin S Wang, Zhengping Shao, Brian J Lee, Verna M Estes, Shan Zha
DNA-PKcs phosphorylation at the T2609 cluster alters the repair pathway choice during immunoglobulin class switch recombination. Proceedings of the National Academy of Sciences of the United States of America 117 (37) (2020)
Xiaobin S Wang, Junfei Zhao, Foon Wu-Baer, Zhengping Shao, Brian J Lee, Olivia M Cupo, Raúl Rabadán, Jean Gautier, Richard Baer, Shan Zha
CtIP-mediated DNA resection is dispensable for IgH class switch recombination by alternative end-joining. Proceedings of the National Academy of Sciences of the United States of America 117 (41) (2020)
Xiangyu Liu, Xiaobin S Wang, Brian J Lee, Foon K Wu-Baer, Xiaohui Lin, Zhengping Shao, Verna M Estes, Jean Gautier, Richard Baer, Shan Zha
CtIP is essential for early B cell proliferation and development in mice. The Journal of experimental medicine 216 (7) (2019)
Wenxia Jiang, Verna M Estes, Xiaobin S Wang, Zhengping Shao, Brian J Lee, Xiaohui Lin, Jennifer L Crowe, Shan Zha
Phosphorylation at S2053 in Murine (S2056 in Human) DNA-PKcs Is Dispensable for Lymphocyte Development and Class Switch Recombination. Journal of immunology (Baltimore, Md. : 1950) 203 (1) (2019)
Kenta Yamamoto, Jiguang Wang, Lisa Sprinzen, Jun Xu, Christopher J Haddock, Chen Li, Brian J Lee, Denis G Loredan, Wenxia Jiang, Alessandro Vindigni, Dong Wang, Raul Rabadan, Shan Zha
Kinase-dead ATM protein is highly oncogenic and can be preferentially targeted by Topo-isomerase I inhibitors. eLife 5 (2016)

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Publication Activity (10 Years)

Top Topics

Top Venues

Shan Zha