Shinji Kohsaka

ORCID

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 31

Top Venues

Cancer science

NPJ precision oncology

Oncogene

Cancer discovery

This page only lists publications with an associated author ORCID identifier.

Publications

Shinji Kohsaka, Shigehiro Yagishita, Yukina Shirai, Yusuke Matsuno, Toshihide Ueno, Shinya Kojima, Hiroshi Ikeuchi, Masachika Ikegami, Rina Kitada, Ken-Ichi Yoshioka, Kohta Toshimitsu, Kimiyo Tabata, Akira Yokoi, Toshihiko Doi, Noboru Yamamoto, Takashi Owa, Akinobu Hamada, Hiroyuki Mano
A molecular glue RBM39-degrader induces synthetic lethality in cancer cells with homologous recombination repair deficiency. NPJ precision oncology 8 (1) (2024)
Hiroshi Ikeuchi, Yusuke Matsuno, Rika Kusumoto-Matsuo, Shinya Kojima, Toshihide Ueno, Masachika Ikegami, Rina Kitada, Hitomi Sumiyoshi-Okuma, Yuki Kojima, Kan Yonemori, Yasushi Yatabe, Kazuya Takamochi, Kenji Suzuki, Ken-Ichi Yoshioka, Hiroyuki Mano, Shinji Kohsaka
GLI1 confers resistance to PARP inhibitors by activating the DNA damage repair pathway. Oncogene (2024)
Shinji Kohsaka, Shigehiro Yagishita, Yukina Shirai, Yusuke Matsuno, Toshihide Ueno, Shinya Kojima, Hiroshi Ikeuchi, Masachika Ikegami, Rina Kitada, Ken-Ichi Yoshioka, Kohta Toshimitsu, Kimiyo Tabata, Akira Yokoi, Toshihiko Doi, Noboru Yamamoto, Takashi Owa, Akinobu Hamada, Hiroyuki Mano
A molecular glue RBM39-degrader induces synthetic lethality in cancer cells with homologous recombination repair deficiency. NPJ precision oncology 8 (1) (2024)
Hiroshi Ikeuchi, Yusuke Matsuno, Rika Kusumoto-Matsuo, Shinya Kojima, Toshihide Ueno, Masachika Ikegami, Rina Kitada, Hitomi Sumiyoshi-Okuma, Yuki Kojima, Kan Yonemori, Yasushi Yatabe, Kazuya Takamochi, Kenji Suzuki, Ken-Ichi Yoshioka, Hiroyuki Mano, Shinji Kohsaka
GLI1 confers resistance to PARP inhibitors by activating the DNA damage repair pathway. Oncogene (2024)
Hiroshi Ikeuchi, Yusuke Matsuno, Rika Kusumoto-Matsuo, Shinya Kojima, Toshihide Ueno, Masachika Ikegami, Rina Kitada, Hitomi Sumiyoshi-Okuma, Yuki Kojima, Kan Yonemori, Yasushi Yatabe, Kazuya Takamochi, Kenji Suzuki, Ken-Ichi Yoshioka, Hiroyuki Mano, Shinji Kohsaka
Correction: GLI1 confers resistance to PARP inhibitors by activating the DNA damage repair pathway. Oncogene (2024)
Birgit Wilding, Lydia Woelflingseder, Anke Baum, Krzysztof Chylinski, Gintautas Vainorius, Neil Gibson, Irene C Waizenegger, Daniel Gerlach, Martin Augsten, Fiona Spreitzer, Yukina Shirai, Masachika Ikegami, Sylvia Tilandyova, Dirk Scharn, Mark A Pearson, Johannes Popow, Anna C Obenauf, Noboru Yamamoto, Shunsuke Kondo, Frans L Opdam, Annemarie Bruining, Shinji Kohsaka, Norbert Kraut, John Victor Heymach, Flavio Solca, Ralph A Neumuller
Zongertinib (BI 1810631), an irreversible HER2 TKI, spares EGFR signaling and improves therapeutic response in preclinical models and patients with HER2-driven cancers. Cancer discovery (2024)
Hidenori Kage, Aya Shinozaki-Ushiku, Kazunaga Ishigaki, Yusuke Sato, Masahiko Tanabe, Shota Tanaka, Michihiro Tanikawa, Kousuke Watanabe, Shingo Kato, Kiwamu Akagi, Keita Uchino, Kinuko Mitani, Shunji Takahashi, Yuji Miura, Sadakatsu Ikeda, Yasushi Kojima, Kiyotaka Watanabe, Hitoshi Mochizuki, Hironori Yamaguchi, Yoshimasa Kawazoe, Kosuke Kashiwabara, Shinji Kohsaka, Kenji Tatsuno, Tetsuo Ushiku, Kazuhiko Ohe, Yutaka Yatomi, Yasuyuki Seto, Hiroyuki Aburatani, Hiroyuki Mano, Kiyoshi Miyagawa, Katsutoshi Oda
Clinical utility of Todai OncoPanel in the setting of approved comprehensive cancer genomic profiling tests in Japan. Cancer science (2023)
Takeshi Hirose, Masachika Ikegami, Shinya Kojima, Akihiko Yoshida, Makoto Endo, Eijiro Shimada, Masaya Kanahori, Ryunosuke Oyama, Yoshihiro Matsumoto, Yasuharu Nakashima, Akira Kawai, Hiroyuki Mano, Shinji Kohsaka
Extensive analysis of 59 sarcoma-related fusion genes identified pazopanib as a potential inhibitor to COL1A1-PDGFB fusion gene. Cancer science (2023)
Hidenori Kage, Aya Shinozaki-Ushiku, Kazunaga Ishigaki, Yusuke Sato, Masahiko Tanabe, Shota Tanaka, Michihiro Tanikawa, Kousuke Watanabe, Shingo Kato, Kiwamu Akagi, Keita Uchino, Kinuko Mitani, Shunji Takahashi, Yuji Miura, Sadakatsu Ikeda, Yasushi Kojima, Kiyotaka Watanabe, Hitoshi Mochizuki, Hironori Yamaguchi, Yoshimasa Kawazoe, Kosuke Kashiwabara, Shinji Kohsaka, Kenji Tatsuno, Tetsuo Ushiku, Kazuhiko Ohe, Yutaka Yatomi, Yasuyuki Seto, Hiroyuki Aburatani, Hiroyuki Mano, Kiyoshi Miyagawa, Katsutoshi Oda
Clinical utility of Todai OncoPanel in the setting of approved comprehensive cancer genomic profiling tests in Japan. Cancer science (2023)
Takafumi Koyama, Toshio Shimizu, Yuki Kojima, Kazuki Sudo, Hitomi Sumiyoshi Okuma, Tatsunori Shimoi, Hitotshi Ichikawa, Shinji Kohsaka, Ryo Sadachi, Akihiro Hirakawa, Akihiko Yoshida, Reiko Makihara Ando, Toshihide Ueno, Mitsuru Yanagaki, Naoko Matsui, Kenichi Nakamura, Noboru Yamamoto, Kan Yonemori
Clinical activity and exploratory resistance mechanism of milademetan, an MDM2 inhibitor, in intimal sarcoma with MDM2 amplification: an open-label phase 1b/2 study. Cancer discovery (2023)
Kazuki Yamazawa, Kokichi Sugano, Kohji Tanakaya, Satomi Inoue, Haruka Murakami, Moeko Nakashima, Masataka Adachi, Shinya Oki, Takeshi Makabe, Hiroshi Yamashita, Arisa Ueki, Ayako Sasaoka, Ayako Nakashoji, Takayuki Kinoshita, Tatsuo Matsunaga, Masami Arai, Seigo Nakamura, Hiroaki Miyata, Masachika Ikegami, Hiroyuki Mano, Shinji Kohsaka, Akira Matsui
The pathogenic role of the BRCA2 c.7847C>T (p.Ser2616Phe) variant in breast and ovarian cancer predisposition. Cancer science (2023)
Bunpei Miyazaki, Toshihide Ueno, Masanaka Sugiyama, Shinya Kojima, Ayumu Arakawa, Kayoko Tao, Kazuki Tanimura, Kouya Shiraishi, Shigehiro Yagishita, Shinji Kohsaka, Mamoru Kato, Nobutaka Kiyokawa, Yasushi Goto, Yasushi Yatabe, Akinobu Hamada, Hiroyuki Mano, Chitose Ogawa, Yosuke Tanaka
Promoter swapping of truncated PDGFRB drives Ph-like acute lymphoblastic leukemia. NPJ precision oncology 7 (1) (2023)
Hitomi Sumiyoshi Okuma, Hiroshi Yoshida, Yoshihisa Kobayashi, Motoko Arakaki, Chiharu Mizoguchi, Lina Inagaki, Voon Pei Jye, Adam Malik Bin Ismail, Hwoei Fen Soo Hoo, Suhana Yusak, Marcelo Severino B Imasa, Thinh Nguyen Huy, Tu Thai Anh, Shinji Kohsaka, Hiroyuki Mano, Kan Yonemori, Kenichi Nakamura, Yasushi Yatabe
Molecular pathology quality control in Southeast Asia: Results of a Multiregional Quality Assurance Study from MASTER KEY Asia. Cancer science (2023)
Sho Mizuno, Masachika Ikegami, Takafumi Koyama, Kuniko Sunami, Dai Ogata, Hidenori Kage, Mitsuru Yanagaki, Hiroshi Ikeuchi, Toshihide Ueno, Michihiro Tanikawa, Katsutoshi Oda, Yutaka Osuga, Hiroyuki Mano, Shinji Kohsaka
High-throughput functional evaluation of MAP2K1 variants in cancer. Molecular cancer therapeutics (2022)
Sumimasa Nagai, Hiroshi Nishihara, Takayoshi Suzuki, Kazuto Nishio, Hiroya Taniguchi, Katsuya Tsuchihara, Kohei Nakamura, Reika Takamatsu, Toshihide Ueno, Hiroyuki Aburatani, Takashi Kohno, Shinji Kohsaka
Recommendations related to the analytical equivalence assessment of gene panel testing. Cancer science 113 (10) (2022)
Suguru Fukuhara, Yuji Oshikawa-Kumade, Yasunori Kogure, Sumito Shingaki, Hirokazu Kariyazono, Yoshiya Kikukawa, Junji Koya, Yuki Saito, Mariko Tabata, Kota Yoshifuji, Kota Mizuno, Akiko Miyagi Maeshima, Hiromichi Matsushita, Masanaka Sugiyama, Chitose Ogawa, Yoshihiro Inamoto, Takahiro Fukuda, Masato Sugano, Nobuhiko Yamauchi, Yosuke Minami, Makoto Hirata, Teruhiko Yoshida, Takashi Kohno, Shinji Kohsaka, Hiroyuki Mano, Yuichi Shiraishi, Seishi Ogawa, Koji Izutsu, Keisuke Kataoka
Feasibility and clinical utility of comprehensive genomic profiling of hematological malignancies. Cancer science 113 (8) (2022)
Mitsuho Imai, Yoshiaki Nakamura, Kuniko Sunami, Hidenori Kage, Keigo Komine, Takafumi Koyama, Toraji Amano, Daisuke Ennishi, Masashi Kanai, Hirotsugu Kenmotsu, Takahiro Maeda, Sachi Morita, Daisuke Sakai, Hideaki Bando, Akitaka Makiyama, Tatsuya Suzuki, Makoto Hirata, Shinji Kohsaka, Katsuya Tsuchihara, Yoichi Naito, Takayuki Yoshino
Expert panel consensus recommendations on the use of circulating tumor DNA assays for patients with advanced solid tumors. Cancer science 113 (11) (2022)
Kuniko Sunami, Yoichi Naito, Keigo Komine, Toraji Amano, Daisuke Ennishi, Mitsuho Imai, Hidenori Kage, Masashi Kanai, Hirotsugu Kenmotsu, Takafumi Koyama, Takahiro Maeda, Sachi Morita, Daisuke Sakai, Shinji Kohsaka, Katsuya Tsuchihara, Yusuke Saigusa, Takayuki Yoshino
Chronological improvement in precision oncology implementation in Japan. Cancer science 113 (11) (2022)
Takashi Kohno, Mamoru Kato, Shinji Kohsaka, Tomohisa Sudo, Ikuo Tamai, Yuichi Shiraishi, Yusuke Okuma, Daisuke Ogasawara, Tatsuya Suzuki, Teruhiko Yoshida, Hiroyuki Mano
C-CAT: The National Datacenter for Cancer Genomic Medicine in Japan. Cancer discovery 12 (11) (2022)
Hiroshi Ikeuchi, Takeshi Hirose, Masachika Ikegami, Kazuya Takamochi, Kenji Suzuki, Hiroyuki Mano, Shinji Kohsaka
Preclinical assessment of combination therapy of EGFR tyrosine kinase inhibitors in a highly heterogeneous tumor model. Oncogene 41 (17) (2022)
Shinji Kohsaka, Yuichiro Tada, Mizuo Ando, Masato Nakaguro, Yukina Shirai, Toshihide Ueno, Shinya Kojima, Hideaki Hirai, Natsuki Saigusa, Satoshi Kano, Kiyoaki Tsukahara, Takafumi Togashi, Hiroyuki Ozawa, Takahito Kondo, Kenji Okami, Hideaki Takahashi, Daisuke Kawakita, Chihiro Fushimi, Takayoshi Suzuki, Akira Shimizu, Isaku Okamoto, Takuro Okada, Yuichiro Sato, Yorihisa Imanishi, Yoshihiro Watanabe, Akihiro Sakai, Koji Ebisumoto, Yukiko Sato, Makoto Urano, Yoshitaka Honma, Keisuke Yamazaki, Yushi Ueki, Toyoyuki Hanazawa, Yuki Saito, Tomotaka Shimura, Toshitaka Nagao, Hiroyuki Mano
Identification of novel prognostic and predictive biomarkers in salivary duct carcinoma via comprehensive molecular profiling. NPJ precision oncology 6 (1) (2022)
Junya Tabata, Takashi Nakaoku, Mitsugu Araki, Ryunosuke Yoshino, Shinji Kohsaka, Ayaka Otsuka, Masachika Ikegami, Ayako Ui, Shin-Ichiro Kanno, Keiko Miyoshi, Shigeyuki Matsumoto, Yukari Sagae, Akira Yasui, Masakazu Sekijima, Hiroyuki Mano, Yasushi Okuno, Aikou Okamoto, Takashi Kohno
Novel Calcium-Binding Ablating Mutations Induce Constitutive RET Activity and Drive Tumorigenesis. Cancer research 82 (20) (2022)
Masaaki Nagano, Shinji Kohsaka, Takuo Hayashi, Toshihide Ueno, Shinya Kojima, Aya Shinozaki-Ushiku, Shigeki Morita, Masumi Tsuda, Shinya Tanaka, Toshiya Shinohara, Yuko Omori, Fumiko Sugaya, Hiroaki Kato, Yoshiaki Narita, Jun Nakajima, Kenji Suzuki, Kazuya Takamochi, Hiroyuki Mano
Comprehensive molecular profiling of pulmonary pleomorphic carcinoma. NPJ precision oncology 5 (1) (2021)
Ikuko Takeda Nakamura, Masachika Ikegami, Nobuhiko Hasegawa, Takuo Hayashi, Toshihide Ueno, Masahito Kawazu, Shigehiro Yagishita, Yasushi Goto, Yuki Shinno, Yuki Kojima, Kazuya Takamochi, Fumiyuki Takahashi, Kazuhisa Takahashi, Hiroyuki Mano, Shinji Kohsaka
Development of an optimal protocol for molecular profiling of tumor cells in pleural effusions at single-cell level. Cancer science 112 (5) (2021)
Nobuhiko Hasegawa, Shinji Kohsaka, Kana Kurokawa, Yuki Shinno, Ikuko Takeda Nakamura, Toshihide Ueno, Shinya Kojima, Masahito Kawazu, Yoshiyuki Suehara, Muneaki Ishijima, Yasushi Goto, Yuki Kojima, Kan Yonemori, Takuo Hayashi, Tsuyoshi Saito, Takehito Shukuya, Fumiyuki Takahashi, Kazuhisa Takahashi, Hiroyuki Mano
Highly sensitive fusion detection using plasma cell-free RNA in non-small-cell lung cancers. Cancer science 112 (10) (2021)
Kuniko Sunami, Hideaki Bando, Yasushi Yatabe, Yoichi Naito, Hideaki Takahashi, Katsuya Tsuchihara, Shinichi Toyooka, Koshi Mimori, Shinji Kohsaka, Hiroyuki Uetake, Ichiro Kinoshita, Keigo Komine, Masayuki Takeda, Tetsu Hayashida, Kenji Tamura, Kazuto Nishio, Noboru Yamamoto, null null
Appropriate use of cancer comprehensive genome profiling assay using circulating tumor DNA. Cancer science 112 (9) (2021)
Masachika Ikegami, Shinji Kohsaka, Takeshi Hirose, Toshihide Ueno, Satoshi Inoue, Naoki Kanomata, Hideko Yamauchi, Taisuke Mori, Shigeki Sekine, Yoshihiro Inamoto, Yasushi Yatabe, Hiroshi Kobayashi, Sakae Tanaka, Hiroyuki Mano
MicroSEC filters sequence errors for formalin-fixed and paraffin-embedded samples. Communications biology 4 (1) (2021)
Ikuko Takeda Nakamura, Shinji Kohsaka, Masachika Ikegami, Hiroshi Ikeuchi, Toshihide Ueno, Kunhua Li, Tyler S Beyett, Takafumi Koyama, Toshio Shimizu, Noboru Yamamoto, Fumiyuki Takahashi, Kazuhisa Takahashi, Michael J Eck, Hiroyuki Mano
Comprehensive functional evaluation of variants of fibroblast growth factor receptor genes in cancer. NPJ precision oncology 5 (1) (2021)
Shinji Kohsaka, Kenji Tatsuno, Toshihide Ueno, Masaaki Nagano, Aya Shinozaki-Ushiku, Tetsuo Ushiku, Daiya Takai, Masachika Ikegami, Hiroshi Kobayashi, Hidenori Kage, Mizuo Ando, Keisuke Hata, Hiroki Ueda, Shogo Yamamoto, Shinya Kojima, Kumiko Oseto, Keisuke Akaike, Yoshiyuki Suehara, Takuo Hayashi, Tsuyoshi Saito, Fumiyuki Takahashi, Kazuhisa Takahashi, Kazuya Takamochi, Kenji Suzuki, Satoshi Nagayama, Yoshinao Oda, Koshi Mimori, Soichiro Ishihara, Yutaka Yatomi, Takahide Nagase, Jun Nakajima, Sakae Tanaka, Masashi Fukayama, Katsutoshi Oda, Masaomi Nangaku, Kohei Miyazono, Kiyoshi Miyagawa, Hiroyuki Aburatani, Hiroyuki Mano
Comprehensive assay for the molecular profiling of cancer by target enrichment from formalin-fixed paraffin-embedded specimens. Cancer science 110 (4) (2019)
Hidenori Kage, Shinji Kohsaka, Aya Shinozaki-Ushiku, Yoshihisa Hiraishi, Jiro Sato, Kazuhiro Nagayama, Tetsuo Ushiku, Daiya Takai, Jun Nakajima, Kiyoshi Miyagawa, Hiroyuki Aburatani, Hiroyuki Mano, Takahide Nagase
Small lung tumor biopsy samples are feasible for high quality targeted next generation sequencing. Cancer science 110 (8) (2019)
Shinji Kohsaka, Masaaki Nagano, Toshihide Ueno, Yoshiyuki Suehara, Takuo Hayashi, Naoko Shimada, Kazuhisa Takahashi, Kenji Suzuki, Kazuya Takamochi, Fumiyuki Takahashi, Hiroyuki Mano
A method of high-throughput functional evaluation of EGFR gene variants of unknown significance in cancer. Science translational medicine 9 (416) (2018)

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Publication Activity (10 Years)

Top Topics

Top Venues

Shinji Kohsaka