Toshihide Ueno

Publication Activity (10 Years)

Years Active: 2019-2024
Publications (10 Years): 31

Top Topics

Tyrosine Kinase

Small Cell Lung Cancer

Top Venues

NPJ precision oncology

Proceedings of the National Academy of Sciences of the United States of America

Nature cell biology

This page only lists publications with an associated author ORCID identifier.

Publications

Shinji Kohsaka, Shigehiro Yagishita, Yukina Shirai, Yusuke Matsuno, Toshihide Ueno, Shinya Kojima, Hiroshi Ikeuchi, Masachika Ikegami, Rina Kitada, Ken-Ichi Yoshioka, Kohta Toshimitsu, Kimiyo Tabata, Akira Yokoi, Toshihiko Doi, Noboru Yamamoto, Takashi Owa, Akinobu Hamada, Hiroyuki Mano
A molecular glue RBM39-degrader induces synthetic lethality in cancer cells with homologous recombination repair deficiency. NPJ precision oncology 8 (1) (2024)
Mitsuhiro Machitani, Akira Nomura, Taro Yamashita, Mami Yasukawa, Saori Ueki, Ken-Ichi Fujita, Toshihide Ueno, Akio Yamashita, Yoshikazu Tanzawa, Masahiko Watanabe, Toshiyasu Taniguchi, Noriko Saitoh, Shuichi Kaneko, Yukinari Kato, Hiroyuki Mano, Kenkichi Masutomi
Maintenance of R-loop structures by phosphorylated hTERT preserves genome integrity. Nature cell biology (2024)
Hiroshi Ikeuchi, Yusuke Matsuno, Rika Kusumoto-Matsuo, Shinya Kojima, Toshihide Ueno, Masachika Ikegami, Rina Kitada, Hitomi Sumiyoshi-Okuma, Yuki Kojima, Kan Yonemori, Yasushi Yatabe, Kazuya Takamochi, Kenji Suzuki, Ken-Ichi Yoshioka, Hiroyuki Mano, Shinji Kohsaka
GLI1 confers resistance to PARP inhibitors by activating the DNA damage repair pathway. Oncogene (2024)
Shinji Kohsaka, Shigehiro Yagishita, Yukina Shirai, Yusuke Matsuno, Toshihide Ueno, Shinya Kojima, Hiroshi Ikeuchi, Masachika Ikegami, Rina Kitada, Ken-Ichi Yoshioka, Kohta Toshimitsu, Kimiyo Tabata, Akira Yokoi, Toshihiko Doi, Noboru Yamamoto, Takashi Owa, Akinobu Hamada, Hiroyuki Mano
A molecular glue RBM39-degrader induces synthetic lethality in cancer cells with homologous recombination repair deficiency. NPJ precision oncology 8 (1) (2024)
Fumiaki Mukohara, Kazuma Iwata, Takamasa Ishino, Takashi Inozume, Joji Nagasaki, Youki Ueda, Ken Suzawa, Toshihide Ueno, Hideki Ikeda, Katsushige Kawase, Yuka Saeki, Shusuke Kawashima, Kazuo Yamashita, Yu Kawahara, Yasuhiro Nakamura, Akiko Honobe-Tabuchi, Hiroko Watanabe, Hiromichi Dansako, Tatsuyoshi Kawamura, Yutaka Suzuki, Hiroaki Honda, Hiroyuki Mano, Shinichi Toyooka, Masahito Kawazu, Yosuke Togashi
Somatic mutations in tumor-infiltrating lymphocytes impact on antitumor immunity. Proceedings of the National Academy of Sciences of the United States of America 121 (35) (2024)
Fumiaki Mukohara, Kazuma Iwata, Takamasa Ishino, Takashi Inozume, Joji Nagasaki, Youki Ueda, Ken Suzawa, Toshihide Ueno, Hideki Ikeda, Katsushige Kawase, Yuka Saeki, Shusuke Kawashima, Kazuo Yamashita, Yu Kawahara, Yasuhiro Nakamura, Akiko Honobe-Tabuchi, Hiroko Watanabe, Hiromichi Dansako, Tatsuyoshi Kawamura, Yutaka Suzuki, Hiroaki Honda, Hiroyuki Mano, Shinichi Toyooka, Masahito Kawazu, Yosuke Togashi
Somatic mutations in tumor-infiltrating lymphocytes impact on antitumor immunity. Proceedings of the National Academy of Sciences of the United States of America 121 (35) (2024)
Mitsuhiro Machitani, Akira Nomura, Taro Yamashita, Mami Yasukawa, Saori Ueki, Ken-Ichi Fujita, Toshihide Ueno, Akio Yamashita, Yoshikazu Tanzawa, Masahiko Watanabe, Toshiyasu Taniguchi, Noriko Saitoh, Shuichi Kaneko, Yukinari Kato, Hiroyuki Mano, Kenkichi Masutomi
Maintenance of R-loop structures by phosphorylated hTERT preserves genome integrity. Nature cell biology 26 (6) (2024)
Mitsuhiro Machitani, Akira Nomura, Taro Yamashita, Mami Yasukawa, Saori Ueki, Ken-Ichi Fujita, Toshihide Ueno, Akio Yamashita, Yoshikazu Tanzawa, Masahiko Watanabe, Toshiyasu Taniguchi, Noriko Saitoh, Shuichi Kaneko, Yukinari Kato, Hiroyuki Mano, Kenkichi Masutomi
Maintenance of R-loop structures by phosphorylated hTERT preserves genome integrity. Nature cell biology 26 (6) (2024)
Hiroshi Ikeuchi, Yusuke Matsuno, Rika Kusumoto-Matsuo, Shinya Kojima, Toshihide Ueno, Masachika Ikegami, Rina Kitada, Hitomi Sumiyoshi-Okuma, Yuki Kojima, Kan Yonemori, Yasushi Yatabe, Kazuya Takamochi, Kenji Suzuki, Ken-Ichi Yoshioka, Hiroyuki Mano, Shinji Kohsaka
GLI1 confers resistance to PARP inhibitors by activating the DNA damage repair pathway. Oncogene (2024)
Hiroshi Ikeuchi, Yusuke Matsuno, Rika Kusumoto-Matsuo, Shinya Kojima, Toshihide Ueno, Masachika Ikegami, Rina Kitada, Hitomi Sumiyoshi-Okuma, Yuki Kojima, Kan Yonemori, Yasushi Yatabe, Kazuya Takamochi, Kenji Suzuki, Ken-Ichi Yoshioka, Hiroyuki Mano, Shinji Kohsaka
Correction: GLI1 confers resistance to PARP inhibitors by activating the DNA damage repair pathway. Oncogene (2024)
Fumiaki Mukohara, Kazuma Iwata, Takamasa Ishino, Takashi Inozume, Joji Nagasaki, Youki Ueda, Ken Suzawa, Toshihide Ueno, Hideki Ikeda, Katsushige Kawase, Yuka Saeki, Shusuke Kawashima, Kazuo Yamashita, Yu Kawahara, Yasuhiro Nakamura, Akiko Honobe-Tabuchi, Hiroko Watanabe, Hiromichi Dansako, Tatsuyoshi Kawamura, Yutaka Suzuki, Hiroaki Honda, Hiroyuki Mano, Shinichi Toyooka, Masahito Kawazu, Yosuke Togashi
Somatic mutations in tumor-infiltrating lymphocytes impact on antitumor immunity. Proceedings of the National Academy of Sciences of the United States of America 121 (35) (2024)
Takafumi Koyama, Toshio Shimizu, Yuki Kojima, Kazuki Sudo, Hitomi Sumiyoshi Okuma, Tatsunori Shimoi, Hitotshi Ichikawa, Shinji Kohsaka, Ryo Sadachi, Akihiro Hirakawa, Akihiko Yoshida, Reiko Makihara Ando, Toshihide Ueno, Mitsuru Yanagaki, Naoko Matsui, Kenichi Nakamura, Noboru Yamamoto, Kan Yonemori
Clinical activity and exploratory resistance mechanism of milademetan, an MDM2 inhibitor, in intimal sarcoma with MDM2 amplification: an open-label phase 1b/2 study. Cancer discovery (2023)
Yuta Kobayashi, Atsushi Niida, Satoshi Nagayama, Koichi Saeki, Hiroshi Haeno, Kazuki K Takahashi, Shuto Hayashi, Yuki Ozato, Hideyuki Saito, Takanori Hasegawa, Hiromi Nakamura, Taro Tobo, Akihiro Kitagawa, Kuniaki Sato, Dai Shimizu, Hidenari Hirata, Yuichi Hisamatsu, Takeo Toshima, Yusuke Yonemura, Takaaki Masuda, Shinichi Mizuno, Masahito Kawazu, Shinji Kohsaka, Toshihide Ueno, Hiroyuki Mano, Soichiro Ishihara, Mamoru Uemura, Masaki Mori, Yuichiro Doki, Hidetoshi Eguchi, Masanobu Oshima, Yutaka Suzuki, Tatsuhiro Shibata, Koshi Mimori
Subclonal accumulation of immune escape mechanisms in microsatellite instability-high colorectal cancers. British journal of cancer (2023)
Bunpei Miyazaki, Toshihide Ueno, Masanaka Sugiyama, Shinya Kojima, Ayumu Arakawa, Kayoko Tao, Kazuki Tanimura, Kouya Shiraishi, Shigehiro Yagishita, Shinji Kohsaka, Mamoru Kato, Nobutaka Kiyokawa, Yasushi Goto, Yasushi Yatabe, Akinobu Hamada, Hiroyuki Mano, Chitose Ogawa, Yosuke Tanaka
Promoter swapping of truncated PDGFRB drives Ph-like acute lymphoblastic leukemia. NPJ precision oncology 7 (1) (2023)
Jo Sasame, Naoki Ikegaya, Masahito Kawazu, Manabu Natsumeda, Takahiro Hayashi, Masataka Isoda, Kaishi Satomi, Arata Tomiyama, Akito Oshima, Hirokuni Honma, Yohei Miyake, Katsuhiro Takabayashi, Taishi Nakamura, Toshihide Ueno, Yuko Matsushita, Hiromichi Iwashita, Yu Kanemaru, Hidetoshi Murata, Akihide Ryo, Keita Terashima, Shoji Yamanaka, Yukihiko Fujii, Hiroyuki Mano, Takashi Komori, Koichi Ichimura, Daniel P Cahill, Hiroaki Wakimoto, Tetsuya Yamamoto, Kensuke Tateishi
HSP90 Inhibition Overcomes Resistance to Molecular Targeted Therapy in BRAFV600E-mutant High-grade Glioma. Clinical cancer research : an official journal of the American Association for Cancer Research 28 (11) (2022)
Sho Mizuno, Masachika Ikegami, Takafumi Koyama, Kuniko Sunami, Dai Ogata, Hidenori Kage, Mitsuru Yanagaki, Hiroshi Ikeuchi, Toshihide Ueno, Michihiro Tanikawa, Katsutoshi Oda, Yutaka Osuga, Hiroyuki Mano, Shinji Kohsaka
High-throughput functional evaluation of MAP2K1 variants in cancer. Molecular cancer therapeutics (2022)
Akihito Kawazoe, Akihito Kawazoe, Toshihiro Suzuki, Masahito Kawazu, Toshihide Ueno, Kazumasa Takenouchi, Yoshiaki Nakamura, Yasutoshi Kuboki, Daisuke Kotani, Takashi Kojima, Hideaki Bando, Saori Mishima, Takeshi Kuwata, Naoya Sakamoto, Jun Watanabe, Hiroyuki Mano, Masafumi Ikeda, Kohei Shitara, Itraru Endo, Tetsuya Nakatsura, Takayuki Yoshino
Transcriptomic Profiling of MSI-H/dMMR Gastrointestinal Tumors to Identify Determinants of Responsiveness to Anti-PD-1 Therapy. Clinical cancer research : an official journal of the American Association for Cancer Research 28 (10) (2022)
Shinji Kohsaka, Yuichiro Tada, Mizuo Ando, Masato Nakaguro, Yukina Shirai, Toshihide Ueno, Shinya Kojima, Hideaki Hirai, Natsuki Saigusa, Satoshi Kano, Kiyoaki Tsukahara, Takafumi Togashi, Hiroyuki Ozawa, Takahito Kondo, Kenji Okami, Hideaki Takahashi, Daisuke Kawakita, Chihiro Fushimi, Takayoshi Suzuki, Akira Shimizu, Isaku Okamoto, Takuro Okada, Yuichiro Sato, Yorihisa Imanishi, Yoshihiro Watanabe, Akihiro Sakai, Koji Ebisumoto, Yukiko Sato, Makoto Urano, Yoshitaka Honma, Keisuke Yamazaki, Yushi Ueki, Toyoyuki Hanazawa, Yuki Saito, Tomotaka Shimura, Toshitaka Nagao, Hiroyuki Mano
Identification of novel prognostic and predictive biomarkers in salivary duct carcinoma via comprehensive molecular profiling. NPJ precision oncology 6 (1) (2022)
Takao Morinaga, Takashi Inozume, Masahito Kawazu, Youki Ueda, Nicolas Sax, Kazuo Yamashita, Shusuke Kawashima, Joji Nagasaki, Toshihide Ueno, Jason Lin, Yuuki Ohara, Takeshi Kuwata, Hiroki Yukami, Akihito Kawazoe, Kohei Shitara, Akiko Honobe-Tabuchi, Takehiro Ohnuma, Tatsuyoshi Kawamura, Yoshiyasu Umeda, Yu Kawahara, Yasuhiro Nakamura, Yukiko Kiniwa, Ayako Morita, Eiki Ichihara, Katsuyuki Kiura, Tomohiro Enokida, Makato Tahara, Yoshinori Hasegawa, Hiroyuki Mano, Yutaka Suzuki, Hiroyoshi Nishikawa, Yosuke Togashi
Mixed Response to Cancer Immunotherapy is Driven by Intratumor Heterogeneity and Differential Interlesion Immune Infiltration. Cancer research communications 2 (7) (2022)
Shinichi Namba, Toshihide Ueno, Shinya Kojima, Kenya Kobayashi, Katsushige Kawase, Yosuke Tanaka, Satoshi Inoue, Fumishi Kishigami, Shusuke Kawashima, Noriko Maeda, Tomoko Ogawa, Shoichi Hazama, Yosuke Togashi, Mizuo Ando, Yuichi Shiraishi, Hiroyuki Mano, Masahito Kawazu
Transcript-targeted analysis reveals isoform alterations and double-hop fusions in breast cancer. Communications biology 4 (1) (2021)
Hitomi Jo, Shigehiro Yagishita, Yoshiharu Hayashi, Shoraku Ryu, Mikiko Suzuki, Shinji Kohsaka, Toshihide Ueno, Yuji Matsumoto, Hidehito Horinouchi, Yuichiro Ohe, Shun-Ichi Watanabe, Noriko Motoi, Yasushi Yatabe, Hiroyuki Mano, Kazuhisa Takahashi, Akinobu Hamada
Comparative Study on the Efficacy and Exposure of Molecular Target Agents in Non-small Cell Lung Cancer PDX Models with Driver Genetic Alterations. Molecular cancer therapeutics 21 (2) (2021)
Akihito Kawazoe, Akihito Kawazoe, Masahito Kawazu, Toshihiro Suzuki, Yoshiaki Nakamura, Tetsuya Nakatsura, Takeshi Kuwata, Toshihide Ueno, Yasutoshi Kuboki, Daisuke Kotani, Takashi Kojima, Hiroya Taniguchi, Hiroyuki Mano, Masafumi Ikeda, Kohei Shitara, Itaru Endo, Takayuki Yoshino
A Low Tumor Mutational Burden and PTEN Mutations Are Predictors of a Negative Response to PD-1 Blockade in MSI-H/dMMR Gastrointestinal Tumors. Clinical cancer research : an official journal of the American Association for Cancer Research 27 (13) (2021)
Jun Suzuka, Masumi Tsuda, Lei Wang, Shinji Kohsaka, Karin Kishida, Shingo Semba, Hirokazu Sugino, Sachiyo Aburatani, Martin Frauenlob, Takayuki Kurokawa, Shinya Kojima, Toshihide Ueno, Yoshihiro Ohmiya, Hiroyuki Mano, Kazunori Yasuda, Jian Ping Gong, Shinya Tanaka
Rapid reprogramming of tumour cells into cancer stem cells on double-network hydrogels. Nature biomedical engineering 5 (8) (2021)
Yosuke Tanaka, Fumiko Chiwaki, Shinya Kojima, Masahito Kawazu, Masayuki Komatsu, Toshihide Ueno, Satoshi Inoue, Shigeki Sekine, Keisuke Matsusaki, Hiromichi Matsushita, Narikazu Boku, Yae Kanai, Yasushi Yatabe, Hiroki Sasaki, Hiroyuki Mano
Multi-omic profiling of peritoneal metastases in gastric cancer identifies molecular subtypes and therapeutic vulnerabilities. Nature cancer 2 (9) (2021)
Masachika Ikegami, Shinji Kohsaka, Takeshi Hirose, Toshihide Ueno, Satoshi Inoue, Naoki Kanomata, Hideko Yamauchi, Taisuke Mori, Shigeki Sekine, Yoshihiro Inamoto, Yasushi Yatabe, Hiroshi Kobayashi, Sakae Tanaka, Hiroyuki Mano
MicroSEC filters sequence errors for formalin-fixed and paraffin-embedded samples. Communications biology 4 (1) (2021)
Masachika Ikegami, Shinji Kohsaka, Toshihide Ueno, Yukihide Momozawa, Satoshi Inoue, Kenji Tamura, Akihiko Shimomura, Noriko Hosoya, Hiroshi Kobayashi, Sakae Tanaka, Hiroyuki Mano
High-throughput functional evaluation of BRCA2 variants of unknown significance. Nature communications 11 (1) (2020)
Kensuke Tateishi, Yohei Miyake, Masahito Kawazu, Nobuyoshi Sasaki, Taishi Nakamura, Jo Sasame, Yukie Yoshii, Toshihide Ueno, Jun Watanabe, Yuko Matsushita, Norio Shiba, Naoko Udaka, Kentaro Ohki, Alexandria L Fink, Shilpa S Tummala, Manabu Natsumeda, Naoki Ikegaya, Mayuko Nishi, Makoto Ohtake, Ryohei Miyazaki, Jun Suenaga, Hidetoshi Murata, Ichio Aoki, Julie J Miller, Yukihiko Fujii, Akihide Ryo, Shoji Yamanaka, Hiroyuki Mano, Daniel P Cahill, Hiroaki Wakimoto, Andrew S Chi, Tracy T Batchelor, Motoo Nagane, Koichi Ichimura, Tetsuya Yamamoto
A Hyperactive RelA/p65-Hexokinase 2 Signaling Axis Drives Primary Central Nervous System Lymphoma. Cancer research 80 (23) (2020)
Shogo Kumagai, Yosuke Togashi, Takahiro Kamada, Eri Sugiyama, Hitomi Nishinakamura, Yoshiko Takeuchi, Kochin Vitaly, Kota Itahashi, Yuka Maeda, Shigeyuki Matsui, Takuma Shibahara, Yasuho Yamashita, Takuma Irie, Ayaka Tsuge, Shota Fukuoka, Akihito Kawazoe, Hibiki Udagawa, Keisuke Kirita, Keiju Aokage, Genichiro Ishii, Takeshi Kuwata, Kenta Nakama, Masahito Kawazu, Toshihide Ueno, Naoya Yamazaki, Koichi Goto, Masahiro Tsuboi, Hiroyuki Mano, Toshihiko Doi, Kohei Shitara, Hiroyoshi Nishikawa
The PD-1 expression balance between effector and regulatory T cells predicts the clinical efficacy of PD-1 blockade therapies. Nature immunology 21 (11) (2020)
Shinobu Tsuzuki, Takahiko Yasuda, Shinya Kojima, Masahito Kawazu, Koshi Akahane, Takeshi Inukai, Masue Imaizumi, Takanobu Morishita, Koichi Miyamura, Toshihide Ueno, Sivasundaram Karnan, Akinobu Ota, Toshinori Hyodo, Hiroyuki Konishi, Masashi Sanada, Hirokazu Nagai, Keizo Horibe, Akihiro Tomita, Kyogo Suzuki, Hideki Muramatsu, Yoshiyuki Takahashi, Yasushi Miyazaki, Itaru Matsumura, Hitoshi Kiyoi, Yoshitaka Hosokawa, Hiroyuki Mano, Fumihiko Hayakawa
Targeting MEF2D-fusion Oncogenic Transcriptional Circuitries in B-cell Precursor Acute Lymphoblastic Leukemia. Blood cancer discovery 1 (1) (2020)
Daisuke Hayakawa, Fumiyuki Takahashi, Yoichiro Mitsuishi, Ken Tajima, Moulid Hidayat, Wira Winardi, Hiroaki Ihara, Koichiro Kanamori, Naohisa Matsumoto, Tetsuhiko Asao, Ryo Ko, Takehito Shukuya, Kazuya Takamochi, Takuo Hayashi, Yoshiyuki Suehara, Ikuko Takeda Nakamura, Toshihide Ueno, Shinji Kohsaka, Hiroyuki Mano, Kazuhisa Takahashi
Activation of insulin-like growth factor-1 receptor confers acquired resistance to osimertinib in non-small cell lung cancer with EGFR T790M mutation. Thoracic cancer 11 (1) (2019)
Satoshi Inoue, Yasushi Hirota, Toshihide Ueno, Yamato Fukui, Emiko Yoshida, Takuo Hayashi, Shinya Kojima, Reina Takeyama, Taiki Hashimoto, Tohru Kiyono, Masako Ikemura, Ayumi Taguchi, Tomoki Tanaka, Yosuke Tanaka, Seiji Sakata, Kengo Takeuchi, Ayako Muraoka, Satoko Osuka, Tsuyoshi Saito, Katsutoshi Oda, Yutaka Osuga, Yasuhisa Terao, Masahito Kawazu, Hiroyuki Mano
Uterine adenomyosis is an oligoclonal disorder associated with KRAS mutations. Nature communications 10 (1) (2019)