Shiqing Xu

Publication Activity (10 Years)

Years Active: 2021-2024
Publications (10 Years): 29

Top Topics

Transition Metal

Respiratory Syndrome Coronavirus

Histone Deacetylase

Anti Inflammatory

Top Venues

Journal of medicinal chemistry

ACS chemical biology

ACS central science

This page only lists publications with an associated author ORCID identifier.

Publications

Yan J Sheng, Syuan-Ting A Kuo, Tingyuan Yang, Hanyuan E Zhang, David H Russell, Xin Yan, Shiqing Xu, Wenshe Ray Liu, Carol A Fierke
BRD4354 Is a Potent Covalent Inhibitor against the SARS-CoV-2 Main Protease. Biochemistry (2024)
Lauren R Blankenship, Kai S Yang, Veerabhadra R Vulupala, Yugendar R Alugubelli, Kaustav Khatua, Demonta Coleman, Xinyu R Ma, Banumathi Sankaran, Chia-Chuan D Cho, Yuying Ma, Benjamin W Neuman, Shiqing Xu, Wenshe Ray Liu
SARS-CoV-2 Main Protease Inhibitors That Leverage Unique Interactions with the Solvent Exposed S3 Site of the Enzyme. ACS medicinal chemistry letters 15 (6) (2024)
Yugendar R Alugubelli, Jing Xiao, Kaustav Khatua, Sathish Kumar, Long Sun, Yuying Ma, Xinyu R Ma, Veerabhadra R Vulupala, Sandeep Atla, Lauren R Blankenship, Demonta Coleman, Xuping Xie, Benjamin W Neuman, Wenshe Ray Liu, Shiqing Xu
Discovery of First-in-Class PROTAC Degraders of SARS-CoV-2 Main Protease. Journal of medicinal chemistry 67 (8) (2024)
Yan J Sheng, Syuan-Ting A Kuo, Tingyuan Yang, Hanyuan E Zhang, David H Russell, Xin Yan, Shiqing Xu, Wenshe Ray Liu, Carol A Fierke
BRD4354 Is a Potent Covalent Inhibitor against the SARS-CoV-2 Main Protease. Biochemistry (2024)
Yan J Sheng, Syuan-Ting A Kuo, Tingyuan Yang, Hanyuan E Zhang, David H Russell, Xin Yan, Shiqing Xu, Wenshe Ray Liu, Carol A Fierke
BRD4354 Is a Potent Covalent Inhibitor against the SARS-CoV-2 Main Protease. Biochemistry (2024)
Peng-Hsun Chase Chen, Xuejiao Shirley Guo, Hanyuan Eric Zhang, Gopal K Dubey, Zhi Zachary Geng, Carol A Fierke, Shiqing Xu, Joshua Trae Hampton, Wenshe Ray Liu
Leveraging a Phage-Encoded Noncanonical Amino Acid: A Novel Pathway to Potent and Selective Epigenetic Reader Protein Inhibitors. ACS central science 10 (4) (2024)
Yugendar R Alugubelli, Jing Xiao, Kaustav Khatua, Sathish Kumar, Long Sun, Yuying Ma, Xinyu R Ma, Veerabhadra R Vulupala, Sandeep Atla, Lauren R Blankenship, Demonta Coleman, Xuping Xie, Benjamin W Neuman, Wenshe Ray Liu, Shiqing Xu
Discovery of First-in-Class PROTAC Degraders of SARS-CoV-2 Main Protease. Journal of medicinal chemistry (2024)
Yugendar R Alugubelli, Jing Xiao, Kaustav Khatua, Sathish Kumar, Long Sun, Yuying Ma, Xinyu R Ma, Veerabhadra R Vulupala, Sandeep Atla, Lauren R Blankenship, Demonta Coleman, Xuping Xie, Benjamin W Neuman, Wenshe Ray Liu, Shiqing Xu
Discovery of First-in-Class PROTAC Degraders of SARS-CoV-2 Main Protease. Journal of medicinal chemistry 67 (8) (2024)
Lauren R Blankenship, Kai S Yang, Veerabhadra R Vulupala, Yugendar R Alugubelli, Kaustav Khatua, Demonta Coleman, Xinyu R Ma, Banumathi Sankaran, Chia-Chuan D Cho, Yuying Ma, Benjamin W Neuman, Shiqing Xu, Wenshe Ray Liu
SARS-CoV-2 Main Protease Inhibitors That Leverage Unique Interactions with the Solvent Exposed S3 Site of the Enzyme. ACS medicinal chemistry letters 15 (6) (2024)
Yugendar R Alugubelli, Jing Xiao, Kaustav Khatua, Sathish Kumar, Long Sun, Yuying Ma, Xinyu R Ma, Veerabhadra R Vulupala, Sandeep Atla, Lauren R Blankenship, Demonta Coleman, Xuping Xie, Benjamin W Neuman, Wenshe Ray Liu, Shiqing Xu
Discovery of First-in-Class PROTAC Degraders of SARS-CoV-2 Main Protease. Journal of medicinal chemistry 67 (8) (2024)
Peng-Hsun Chase Chen, Xuejiao Shirley Guo, Hanyuan Eric Zhang, Gopal K Dubey, Zhi Zachary Geng, Carol A Fierke, Shiqing Xu, Joshua Trae Hampton, Wenshe Ray Liu
Leveraging a Phage-Encoded Noncanonical Amino Acid: A Novel Pathway to Potent and Selective Epigenetic Reader Protein Inhibitors. ACS central science 10 (4) (2024)
Yan J Sheng, Syuan-Ting A Kuo, Tingyuan Yang, Hanyuan E Zhang, David H Russell, Xin Yan, Shiqing Xu, Wenshe Ray Liu, Carol A Fierke
BRD4354 Is a Potent Covalent Inhibitor against the SARS-CoV-2 Main Protease. Biochemistry (2024)
Yugendar R Alugubelli, Jing Xiao, Kaustav Khatua, Sathish Kumar, Long Sun, Yuying Ma, Xinyu R Ma, Veerabhadra R Vulupala, Sandeep Atla, Lauren R Blankenship, Demonta Coleman, Xuping Xie, Benjamin W Neuman, Wenshe Ray Liu, Shiqing Xu
Discovery of First-in-Class PROTAC Degraders of SARS-CoV-2 Main Protease. Journal of medicinal chemistry (2024)
Yugendar R Alugubelli, Jing Xiao, Kaustav Khatua, Sathish Kumar, Long Sun, Yuying Ma, Xinyu R Ma, Veerabhadra R Vulupala, Sandeep Atla, Lauren R Blankenship, Demonta Coleman, Xuping Xie, Benjamin W Neuman, Wenshe Ray Liu, Shiqing Xu
Discovery of First-in-Class PROTAC Degraders of SARS-CoV-2 Main Protease. Journal of medicinal chemistry 67 (8) (2024)
Zhi Zachary Geng, Sandeep Atla, Namir Shaabani, Veerabhadra Vulupala, Kai S Yang, Yugendar R Alugubelli, Kaustav Khatua, Peng-Hsun Chase Chen, Jing Xiao, Lauren R Blankenship, Xinyu R Ma, Erol C Vatansever, Chia-Chuan D Cho, Yuying Ma, Robert Allen, Henry Ji, Shiqing Xu, Wenshe Ray Liu
A Systematic Survey of Reversibly Covalent Dipeptidyl Inhibitors of the SARS-CoV-2 Main Protease. Journal of medicinal chemistry (2023)
Kai S Yang, Lauren R Blankenship, Syuan-Ting Alex Kuo, Yan J Sheng, Pingwei Li, Carol A Fierke, David H Russell, Xin Yan, Shiqing Xu, Wenshe Ray Liu
A Novel Y-Shaped, S-O-N-O-S-Bridged Cross-Link between Three Residues C22, C44, and K61 Is Frequently Observed in the SARS-CoV-2 Main Protease. ACS chemical biology 18 (3) (2023)
Kai S Yang, Lauren R Blankenship, Syuan-Ting Alex Kuo, Yan J Sheng, Pingwei Li, Carol A Fierke, David H Russell, Xin Yan, Shiqing Xu, Wenshe Ray Liu
A Novel Y-Shaped, S-O-N-O-S-Bridged Cross-Link between Three Residues C22, C44, and K61 Is Frequently Observed in the SARS-CoV-2 Main Protease. ACS chemical biology 18 (3) (2023)
Kai S Yang, Lauren R Blankenship, Syuan-Ting Alex Kuo, Yan J Sheng, Pingwei Li, Carol A Fierke, David H Russell, Xin Yan, Shiqing Xu, Wenshe Ray Liu
A Novel Y-Shaped, S-O-N-O-S-Bridged Cross-Link between Three Residues C22, C44, and K61 Is Frequently Observed in the SARS-CoV-2 Main Protease. ACS chemical biology (2023)
Yugendar R Alugubelli, Jing Xiao, Kaustav Khatua, Sathish Kumar, Yuying Ma, Xinyu R Ma, Veerabhadra R Vulupala, Sandeep R Atla, Lauren Blankenship, Demonta Coleman, Benjamin W Neuman, Wenshe Ray Liu, Shiqing Xu
Discovery of First-in-Class PROTAC Degraders of SARS-CoV-2 Main Protease. bioRxiv : the preprint server for biology (2023)
Kai S Yang, Lauren R Blankenship, Syuan-Ting Alex Kuo, Yan J Sheng, Pingwei Li, Carol A Fierke, David H Russell, Xin Yan, Shiqing Xu, Wenshe Ray Liu
A Novel Y-Shaped, S-O-N-O-S-Bridged Cross-Link between Three Residues C22, C44, and K61 Is Frequently Observed in the SARS-CoV-2 Main Protease. ACS chemical biology 18 (3) (2023)
Kai S Yang, Lauren R Blankenship, Syuan-Ting Alex Kuo, Yan J Sheng, Pingwei Li, Carol A Fierke, David H Russell, Xin Yan, Shiqing Xu, Wenshe Ray Liu
A Novel Y-Shaped, S-O-N-O-S-Bridged Cross-Link between Three Residues C22, C44, and K61 Is Frequently Observed in the SARS-CoV-2 Main Protease. ACS chemical biology 18 (3) (2023)
Joshua Trae Hampton, Tyler J Lalonde, Jeffery M Tharp, Yadagiri Kurra, Yugendar R Alugubelli, Christopher M Roundy, Gabriel L Hamer, Shiqing Xu, Wenshe Ray Liu
Novel Regioselective Approach to Cyclize Phage-Displayed Peptides in Combination with Epitope-Directed Selection to Identify a Potent Neutralizing Macrocyclic Peptide for SARS-CoV-2. ACS chemical biology 17 (10) (2022)
Kai S Yang, Sunshine Z Leeuwon, Shiqing Xu, Wenshe Ray Liu
Evolutionary and Structural Insights about Potential SARS-CoV-2 Evasion of Nirmatrelvir. Journal of medicinal chemistry 65 (13) (2022)
Jared S Morse, Yan J Sheng, Joshua Trae Hampton, Lauralee D Sylvain, Sukant Das, Yugendar R Alugubelli, Peng-Hsun Chase Chen, Kai S Yang, Shiqing Xu, Carol A Fierke, Wenshe Ray Liu
Phage-assisted, active site-directed ligand evolution of a potent and selective histone deacetylase 8 inhibitor. Protein science : a publication of the Protein Society 31 (12) (2022)
Heyong Cheng, Tingyuan Yang, Madison Edwards, Shuli Tang, Shiqing Xu, Xin Yan
Picomole-Scale Transition Metal Electrocatalysis Screening Platform for Discovery of Mild C-C Coupling and C-H Arylation through in Situ Anodically Generated Cationic Pd. Journal of the American Chemical Society 144 (3) (2022)
Wenyue Cao, Chia-Chuan Dean Cho, Zhi Zachary Geng, Namir Shaabani, Xinyu R Ma, Erol C Vatansever, Yugendar R Alugubelli, Yuying Ma, Sankar P Chaki, William H Ellenburg, Kai S Yang, Yuchen Qiao, Robert Allen, Benjamin W Neuman, Henry Ji, Shiqing Xu, Wenshe Ray Liu
Evaluation of SARS-CoV-2 Main Protease Inhibitors Using a Novel Cell-Based Assay. ACS central science 8 (2) (2022)
Yuying Ma, Kai S Yang, Zhi Zachary Geng, Yugendar R Alugubelli, Namir Shaabani, Erol C Vatansever, Xinyu R Ma, Chia-Chuan Cho, Kaustav Khatua, Lauren Blankenship, Ge Yu, Banumathi Sankaran, Pingwei Li, Robert Allen, Henry Ji, Shiqing Xu, Wenshe Ray Liu
The P3 O - Tert -Butyl-Threonine is Key to High Cellular and Antiviral Potency for Aldehyde-Based SARS-CoV-2 Main Protease Inhibitors. bioRxiv : the preprint server for biology (2021)
Xiaoping Fu, Qingqing Qi, Shiqing Xu, Ei-Ichi Negishi
Chemo- and Stereoselective Dearomative Coupling of Indoles and Bielectrophilic β-Imino Boronic Esters via Imine-Induced 1,2-Boronate Migration. Organic letters 23 (22) (2021)
Yugendar R Alugubelli, Zhi Zachary Geng, Kai S Yang, Namir Shaabani, Kaustav Khatua, Xinyu R Ma, Erol C Vatansever, Chia-Chuan Cho, Yuying Ma, Lauren Blankenship, Ge Yu, Banumathi Sankaran, Pingwei Li, Robert Allen, Henry Ji, Shiqing Xu, Wenshe Ray Liu
The N -Terminal Carbamate is Key to High Cellular and Antiviral Potency for Boceprevir-Based SARS-CoV-2 Main Protease Inhibitors. bioRxiv : the preprint server for biology (2021)