Simon Cocklin

Publication Activity (10 Years)

Years Active: 2016-2023
Publications (10 Years): 18

Top Topics

Men Who Have Sex With Men

Molecular Dynamics Simulations

Human Immunodeficiency Virus

Emergency Department

Top Venues

Molecules (Basel, Switzerland)

Journal of medicinal chemistry

Life (Basel, Switzerland)

This page only lists publications with an associated author ORCID identifier.

Publications

Shujing Xu, Lin Sun, Michael Barnett, Xujie Zhang, Dang Ding, Anushka Gattu, Dazhou Shi, Jamie R H Taka, Wenli Shen, Xiangyi Jiang, Simon Cocklin, Erik De Clercq, Christophe Pannecouque, David C Goldstone, Xinyong Liu, Alexej Dick, Peng Zhan
Discovery, Crystallographic Studies, and Mechanistic Investigations of Novel Phenylalanine Derivatives Bearing a Quinazolin-4-one Scaffold as Potent HIV Capsid Modulators. Journal of medicinal chemistry (2023)
Shujing Xu, Lin Sun, Waleed A Zalloum, Tianguang Huang, Xujie Zhang, Dang Ding, Xiaoyu Shao, Xiangyi Jiang, Fabao Zhao, Simon Cocklin, Erik De Clercq, Christophe Pannecouque, Alexej Dick, Xinyong Liu, Peng Zhan
Discovery and Mechanistic Investigation of Piperazinone Phenylalanine Derivatives with Terminal Indole or Benzene Ring as Novel HIV-1 Capsid Modulators. Molecules (Basel, Switzerland) 27 (23) (2022)
Shujing Xu, Lin Sun, Waleed A Zalloum, Tianguang Huang, Xujie Zhang, Dang Ding, Xiaoyu Shao, Xiangyi Jiang, Fabao Zhao, Simon Cocklin, Erik De Clercq, Christophe Pannecouque, Alexej Dick, Xinyong Liu, Peng Zhan
Discovery and Mechanistic Investigation of Piperazinone Phenylalanine Derivatives with Terminal Indole or Benzene Ring as Novel HIV-1 Capsid Modulators. Molecules (Basel, Switzerland) 27 (23) (2022)
Xujie Zhang, Lin Sun, Shujing Xu, Xiaoyu Shao, Ziyi Li, Dang Ding, Xiangyi Jiang, Shujie Zhao, Simon Cocklin, Erik De Clercq, Christophe Pannecouque, Alexej Dick, Xinyong Liu, Peng Zhan
Design, Synthesis, and Mechanistic Study of 2-Pyridone-Bearing Phenylalanine Derivatives as Novel HIV Capsid Modulators. Molecules (Basel, Switzerland) 27 (21) (2022)
Shujing Xu, Lin Sun, Waleed A Zalloum, Tianguang Huang, Xujie Zhang, Dang Ding, Xiaoyu Shao, Xiangyi Jiang, Fabao Zhao, Simon Cocklin, Erik De Clercq, Christophe Pannecouque, Alexej Dick, Xinyong Liu, Peng Zhan
Discovery and Mechanistic Investigation of Piperazinone Phenylalanine Derivatives with Terminal Indole or Benzene Ring as Novel HIV-1 Capsid Modulators. Molecules (Basel, Switzerland) 27 (23) (2022)
Xiangkai Ji, Jing Li, Prem Prakash Sharma, Xiangyi Jiang, Brijesh Rathi, Zhen Gao, Lide Hu, Dongwei Kang, Erik De Clercq, Simon Cocklin, Chuanfeng Liu, Christophe Pannecouque, Alexej Dick, Xinyong Liu, Peng Zhan
Design, Synthesis and Structure-Activity Relationships of Phenylalanine-Containing Peptidomimetics as Novel HIV-1 Capsid Binders Based on Ugi Four-Component Reaction. Molecules (Basel, Switzerland) 27 (18) (2022)
Alexej Dick, Megan E Meuser, Simon Cocklin
Clade-Specific Alterations within the HIV-1 Capsid Protein with Implications for Nuclear Translocation. Biomolecules 12 (5) (2022)
Shujing Xu, Lin Sun, Waleed A Zalloum, Tianguang Huang, Xujie Zhang, Dang Ding, Xiaoyu Shao, Xiangyi Jiang, Fabao Zhao, Simon Cocklin, Erik De Clercq, Christophe Pannecouque, Alexej Dick, Xinyong Liu, Peng Zhan
Discovery and Mechanistic Investigation of Piperazinone Phenylalanine Derivatives with Terminal Indole or Benzene Ring as Novel HIV-1 Capsid Modulators. Molecules (Basel, Switzerland) 27 (23) (2022)
Fortunato Ferrara, Sara D'Angelo, Michael Frank Erasmus, Andre A R Teixeira, Camila Leal-Lopes, Laura P Spector, Thomas J Pohl, Adeline M Fanni, Simon Cocklin, Andrew Raymon Morton Bradbury
Pandemic's silver lining. mAbs 14 (1) (2022)
Alexej Dick, Simon Cocklin
Subtype Differences in the Interaction of HIV-1 Matrix with Calmodulin: Implications for Biological Functions. Biomolecules 11 (9) (2021)
Irina S Shkundina, Alexander A Gall, Alexej Dick, Simon Cocklin, Alexander V Mazin
New RAD51 Inhibitors to Target Homologous Recombination in Human Cells. Genes 12 (6) (2021)
Megan E Meuser, Poli Adi Narayana Reddy, Alexej Dick, Jean Marc Maurancy, Joseph M Salvino, Simon Cocklin
Rapid Optimization of the Metabolic Stability of a Human Immunodeficiency Virus Type-1 Capsid Inhibitor Using a Multistep Computational Workflow. Journal of medicinal chemistry 64 (7) (2021)
Eric Rossi, Megan E Meuser, Camille J Cunanan, Simon Cocklin
Structure, Function, and Interactions of the HIV-1 Capsid Protein. Life (Basel, Switzerland) 11 (2) (2021)
Alexej Dick, Simon Cocklin
Recent Advances in HIV-1 Gag Inhibitor Design and Development. Molecules (Basel, Switzerland) 25 (7) (2020)
Rama Karadsheh, Megan E Meuser, Simon Cocklin
Composition and Orientation of the Core Region of Novel HIV-1 Entry Inhibitors Influences Metabolic Stability. Molecules (Basel, Switzerland) 25 (6) (2020)
Megan E Meuser, Adel Ahmed Rashad Ahmed, Gabriel Ozorowski, Alexej Dick, Andrew B Ward, Simon Cocklin
Field-Based Affinity Optimization of a Novel Azabicyclohexane Scaffold HIV-1 Entry Inhibitor. Molecules (Basel, Switzerland) 24 (8) (2019)
Megan E Meuser, Michael B Murphy, Adel Ahmed Rashad Ahmed, Simon Cocklin
Kinetic Characterization of Novel HIV-1 Entry Inhibitors: Discovery of a Relationship between Off-Rate and Potency. Molecules (Basel, Switzerland) 23 (8) (2018)
Ying N Chan, Austin W Boesch, Nana Y Osei-Owusu, Ali Emileh, Andrew R Crowley, Sarah L Cocklin, Samantha L Finstad, Caitlyn H Linde, Rebecca A Howell, Isaac Zentner, Simon Cocklin, Adam R Miles, Joshua W Eckman, Galit Alter, Joern E Schmitz, Margaret E Ackerman
IgG Binding Characteristics of Rhesus Macaque FcγR. Journal of immunology (Baltimore, Md. : 1950) 197 (7) (2016)