Margaret E Ackerman

Loop profile ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 71

Top Topics

Regulatory T Cells

Herpes Simplex Virus

Immune Response

Top Venues

bioRxiv : the preprint server for biology

Proceedings of the National Academy of Sciences of the United States of America

medRxiv : the preprint server for health sciences

This page only lists publications with an associated author ORCID identifier.

Publications

Leena Abdullah, Francesco E Emiliani, Chinmay M Vaidya, Hannah Stuart, Fred Kolling Iv, Margaret E Ackerman, Li Song, Aaron McKenna, Yina H Huang
Hierarchal single-cell lineage tracing reveals differential fate commitment of CD8 T-cell clones in response to acute infection. bioRxiv : the preprint server for biology (2024)
Katherine Maia McCoy, Margaret E Ackerman, Gevorg Grigoryan
A Comparison of Antibody-Antigen Complex Sequence-to-Structure Prediction Methods and their Systematic Biases. bioRxiv : the preprint server for biology (2024)
Stephen R Walsh, Cynthia L Gay, Shelly T Karuna, Ollivier Hyrien, Timothy Skalland, Kenneth H Mayer, Magdalena E Sobieszczyk, Lindsey R Baden, Paul A Goepfert, Carlos Del Rio, Guiseppe Pantaleo, Philip Andrew, Carissa Karg, Zonglin He, Huiyin Lu, Carmen A Paez, Jane A G Baumblatt, Laura L Polakowski, Wairimu Chege, Maija A Anderson, Sophie Janto, Xue Han, Yunda Huang, Julie B Dumond, Margaret E Ackerman, Adrian B McDermott, Britta Flach, Estelle Piwowar-Manning, Kelly E Seaton, Georgia D Tomaras, David C Montefiori, Lucio Gama, John R Mascola, null null
Safety and pharmacokinetics of VRC07-523LS administered via different routes and doses (HVTN 127/HPTN 087): A Phase I randomized clinical trial. PLoS medicine 21 (6) (2024)
Katherine Maia McCoy, Margaret E Ackerman, Gevorg Grigoryan
A Comparison of Antibody-Antigen Complex Sequence-to-Structure Prediction Methods and their Systematic Biases. bioRxiv : the preprint server for biology (2024)
Stephen R Walsh, Cynthia L Gay, Shelly T Karuna, Ollivier Hyrien, Timothy Skalland, Kenneth H Mayer, Magdalena E Sobieszczyk, Lindsey R Baden, Paul A Goepfert, Carlos Del Rio, Guiseppe Pantaleo, Philip Andrew, Carissa Karg, Zonglin He, Helen Lu, Carmen A Paez, Jane A G Baumblatt, Laura L Polakowski, Wairimu Chege, Sophie Janto, Xue Han, Yunda Huang, Julie Dumond, Margaret E Ackerman, Adrian B McDermott, Britta Flach, Estelle Piwowar-Manning, Kelly E Seaton, Georgia D Tomaras, David C Montefiori, Lucio Gama, John R Mascola, null null
A Randomised Clinical Trial of the Safety and Pharmacokinetics of VRC07-523LS Administered via Different Routes and Doses (HVTN 127/HPTN 087). medRxiv : the preprint server for health sciences (2024)
Natasha S Kelkar, Benjamin S Goldberg, Jeremy Dufloo, Timothée Bruel, Olivier Schwartz, Ann J Hessell, Margaret E Ackerman
Sex- and species-associated differences in complement-mediated immunity in humans and rhesus macaques. mBio (2024)
Natasha S Kelkar, Benjamin S Goldberg, Jeremy Dufloo, Timothée Bruel, Olivier Schwartz, Ann J Hessell, Margaret E Ackerman
Sex- and species-associated differences in complement-mediated immunity in humans and rhesus macaques. mBio 15 (3) (2024)
Stephen R Walsh, Cynthia L Gay, Shelly T Karuna, Ollivier Hyrien, Timothy Skalland, Kenneth H Mayer, Magdalena E Sobieszczyk, Lindsey R Baden, Paul A Goepfert, Carlos Del Rio, Guiseppe Pantaleo, Philip Andrew, Carissa Karg, Zonglin He, Helen Lu, Carmen A Paez, Jane A G Baumblatt, Laura L Polakowski, Wairimu Chege, Sophie Janto, Xue Han, Yunda Huang, Julie Dumond, Margaret E Ackerman, Adrian B McDermott, Britta Flach, Estelle Piwowar-Manning, Kelly E Seaton, Georgia D Tomaras, David C Montefiori, Lucio Gama, John R Mascola, null null
A Randomised Clinical Trial of the Safety and Pharmacokinetics of VRC07-523LS Administered via Different Routes and Doses (HVTN 127/HPTN 087). medRxiv : the preprint server for health sciences (2024)
Stephen R Walsh, Cynthia L Gay, Shelly T Karuna, Ollivier Hyrien, Timothy Skalland, Kenneth H Mayer, Magdalena E Sobieszczyk, Lindsey R Baden, Paul A Goepfert, Carlos Del Rio, Guiseppe Pantaleo, Philip Andrew, Carissa Karg, Zonglin He, Huiyin Lu, Carmen A Paez, Jane A G Baumblatt, Laura L Polakowski, Wairimu Chege, Maija A Anderson, Sophie Janto, Xue Han, Yunda Huang, Julie B Dumond, Margaret E Ackerman, Adrian B McDermott, Britta Flach, Estelle Piwowar-Manning, Kelly E Seaton, Georgia D Tomaras, David C Montefiori, Lucio Gama, John R Mascola, null null
Safety and pharmacokinetics of VRC07-523LS administered via different routes and doses (HVTN 127/HPTN 087): A Phase I randomized clinical trial. PLoS medicine 21 (6) (2024)
Stephen R Walsh, Cynthia L Gay, Shelly T Karuna, Ollivier Hyrien, Timothy Skalland, Kenneth H Mayer, Magdalena E Sobieszczyk, Lindsey R Baden, Paul A Goepfert, Carlos Del Rio, Guiseppe Pantaleo, Philip Andrew, Carissa Karg, Zonglin He, Huiyin Lu, Carmen A Paez, Jane A G Baumblatt, Laura L Polakowski, Wairimu Chege, Maija A Anderson, Sophie Janto, Xue Han, Yunda Huang, Julie B Dumond, Margaret E Ackerman, Adrian B McDermott, Britta Flach, Estelle Piwowar-Manning, Kelly E Seaton, Georgia D Tomaras, David C Montefiori, Lucio Gama, John R Mascola, null null
Safety and pharmacokinetics of VRC07-523LS administered via different routes and doses (HVTN 127/HPTN 087): A Phase I randomized clinical trial. PLoS medicine 21 (6) (2024)
Leena Abdullah, Francesco E Emiliani, Chinmay M Vaidya, Hannah Stuart, Fred Kolling Iv, Margaret E Ackerman, Li Song, Aaron McKenna, Yina H Huang
Hierarchal single-cell lineage tracing reveals differential fate commitment of CD8 T-cell clones in response to acute infection. bioRxiv : the preprint server for biology (2024)
Katherine Maia McCoy, Margaret E Ackerman, Gevorg Grigoryan
A Comparison of Antibody-Antigen Complex Sequence-to-Structure Prediction Methods and their Systematic Biases. bioRxiv : the preprint server for biology (2024)
Stephen R Walsh, Cynthia L Gay, Shelly T Karuna, Ollivier Hyrien, Timothy Skalland, Kenneth H Mayer, Magdalena E Sobieszczyk, Lindsey R Baden, Paul A Goepfert, Carlos Del Rio, Guiseppe Pantaleo, Philip Andrew, Carissa Karg, Zonglin He, Helen Lu, Carmen A Paez, Jane A G Baumblatt, Laura L Polakowski, Wairimu Chege, Sophie Janto, Xue Han, Yunda Huang, Julie Dumond, Margaret E Ackerman, Adrian B McDermott, Britta Flach, Estelle Piwowar-Manning, Kelly E Seaton, Georgia D Tomaras, David C Montefiori, Lucio Gama, John R Mascola, null null
A Randomised Clinical Trial of the Safety and Pharmacokinetics of VRC07-523LS Administered via Different Routes and Doses (HVTN 127/HPTN 087). medRxiv : the preprint server for health sciences (2024)
Stephen R Walsh, Cynthia L Gay, Shelly T Karuna, Ollivier Hyrien, Timothy Skalland, Kenneth H Mayer, Magdalena E Sobieszczyk, Lindsey R Baden, Paul A Goepfert, Carlos Del Rio, Guiseppe Pantaleo, Philip Andrew, Carissa Karg, Zonglin He, Huiyin Lu, Carmen A Paez, Jane A G Baumblatt, Laura L Polakowski, Wairimu Chege, Maija A Anderson, Sophie Janto, Xue Han, Yunda Huang, Julie B Dumond, Margaret E Ackerman, Adrian B McDermott, Britta Flach, Estelle Piwowar-Manning, Kelly E Seaton, Georgia D Tomaras, David C Montefiori, Lucio Gama, John R Mascola, null null
Safety and pharmacokinetics of VRC07-523LS administered via different routes and doses (HVTN 127/HPTN 087): A Phase I randomized clinical trial. PLoS medicine 21 (6) (2024)
Stephen R Walsh, Cynthia L Gay, Shelly T Karuna, Ollivier Hyrien, Timothy Skalland, Kenneth H Mayer, Magdalena E Sobieszczyk, Lindsey R Baden, Paul A Goepfert, Carlos Del Rio, Guiseppe Pantaleo, Philip Andrew, Carissa Karg, Zonglin He, Helen Lu, Carmen A Paez, Jane A G Baumblatt, Laura L Polakowski, Wairimu Chege, Sophie Janto, Xue Han, Yunda Huang, Julie Dumond, Margaret E Ackerman, Adrian B McDermott, Britta Flach, Estelle Piwowar-Manning, Kelly E Seaton, Georgia D Tomaras, David C Montefiori, Lucio Gama, John R Mascola, null null
A Randomised Clinical Trial of the Safety and Pharmacokinetics of VRC07-523LS Administered via Different Routes and Doses (HVTN 127/HPTN 087). medRxiv : the preprint server for health sciences (2024)
Natasha S Kelkar, Benjamin S Goldberg, Jeremy Dufloo, Timothée Bruel, Olivier Schwartz, Ann J Hessell, Margaret E Ackerman
Sex- and species-associated differences in complement-mediated immunity in humans and rhesus macaques. mBio 15 (3) (2024)
Leena Abdullah, Francesco E Emiliani, Chinmay M Vaidya, Hannah Stuart, Fred Kolling Iv, Margaret E Ackerman, Li Song, Aaron McKenna, Yina H Huang
Hierarchal single-cell lineage tracing reveals differential fate commitment of CD8 T-cell clones in response to acute infection. bioRxiv : the preprint server for biology (2024)
Leena Abdullah, Francesco E Emiliani, Chinmay M Vaidya, Hannah Stuart, Fred Kolling Iv, Margaret E Ackerman, Li Song, Aaron McKenna, Yina H Huang
Hierarchal single-cell lineage tracing reveals differential fate commitment of CD8 T-cell clones in response to acute infection. bioRxiv : the preprint server for biology (2024)
Natasha S Kelkar, Benjamin S Goldberg, Jeremy Dufloo, Timothée Bruel, Olivier Schwartz, Ann J Hessell, Margaret E Ackerman
Sex- and species-associated differences in complement-mediated immunity in humans and rhesus macaques. mBio (2024)
Katherine Maia McCoy, Margaret E Ackerman, Gevorg Grigoryan
A Comparison of Antibody-Antigen Complex Sequence-to-Structure Prediction Methods and their Systematic Biases. bioRxiv : the preprint server for biology (2024)
Natasha S Kelkar, Benjamin S Goldberg, Jeremy Dufloo, Timothée Bruel, Olivier Schwartz, Ann J Hessell, Margaret E Ackerman
Sex- and species-associated differences in complement-mediated immunity in humans and rhesus macaques. mBio 15 (3) (2024)
Stephen R Walsh, Cynthia L Gay, Shelly T Karuna, Ollivier Hyrien, Timothy Skalland, Kenneth H Mayer, Magdalena E Sobieszczyk, Lindsey R Baden, Paul A Goepfert, Carlos Del Rio, Guiseppe Pantaleo, Philip Andrew, Carissa Karg, Zonglin He, Helen Lu, Carmen A Paez, Jane A G Baumblatt, Laura L Polakowski, Wairimu Chege, Sophie Janto, Xue Han, Yunda Huang, Julie Dumond, Margaret E Ackerman, Adrian B McDermott, Britta Flach, Estelle Piwowar-Manning, Kelly E Seaton, Georgia D Tomaras, David C Montefiori, Lucio Gama, John R Mascola, null null
A Randomised Clinical Trial of the Safety and Pharmacokinetics of VRC07-523LS Administered via Different Routes and Doses (HVTN 127/HPTN 087). medRxiv : the preprint server for health sciences (2024)
Stephen R Walsh, Cynthia L Gay, Shelly T Karuna, Ollivier Hyrien, Timothy Skalland, Kenneth H Mayer, Magdalena E Sobieszczyk, Lindsey R Baden, Paul A Goepfert, Carlos Del Rio, Guiseppe Pantaleo, Philip Andrew, Carissa Karg, Zonglin He, Huiyin Lu, Carmen A Paez, Jane A G Baumblatt, Laura L Polakowski, Wairimu Chege, Maija A Anderson, Sophie Janto, Xue Han, Yunda Huang, Julie B Dumond, Margaret E Ackerman, Adrian B McDermott, Britta Flach, Estelle Piwowar-Manning, Kelly E Seaton, Georgia D Tomaras, David C Montefiori, Lucio Gama, John R Mascola, null null
Safety and pharmacokinetics of VRC07-523LS administered via different routes and doses (HVTN 127/HPTN 087): A Phase I randomized clinical trial. PLoS medicine 21 (6) (2024)
Stephen R Walsh, Cynthia L Gay, Shelly T Karuna, Ollivier Hyrien, Timothy Skalland, Kenneth H Mayer, Magdalena E Sobieszczyk, Lindsey R Baden, Paul A Goepfert, Carlos Del Rio, Guiseppe Pantaleo, Philip Andrew, Carissa Karg, Zonglin He, Huiyin Lu, Carmen A Paez, Jane A G Baumblatt, Laura L Polakowski, Wairimu Chege, Maija A Anderson, Sophie Janto, Xue Han, Yunda Huang, Julie B Dumond, Margaret E Ackerman, Adrian B McDermott, Britta Flach, Estelle Piwowar-Manning, Kelly E Seaton, Georgia D Tomaras, David C Montefiori, Lucio Gama, John R Mascola, null null
Safety and pharmacokinetics of VRC07-523LS administered via different routes and doses (HVTN 127/HPTN 087): A Phase I randomized clinical trial. PLoS medicine 21 (6) (2024)
Ruth I Connor, Mrunal Sakharkar, C Garrett Rappazzo, Chengzi I Kaku, Nicholas C Curtis, Seungmin Shin, Wendy F Wieland-Alter, Joshua A Weiner, Margaret E Ackerman, Laura M Walker, Jiwon Lee, Peter F Wright
Characteristics and functions of infection-enhancing antibodies to the N-terminal domain of SARS-CoV-2. bioRxiv : the preprint server for biology (2023)
Natasha S Kelkar, Benjamin S Goldberg, Jérémy Dufloo, Timothee Bruel, Olivier Schwartz, Ann J Hessell, Margaret E Ackerman
Sex and species associated differences in Complement-mediated immunity in Humans and Rhesus macaques. bioRxiv : the preprint server for biology (2023)
Yunda Huang, Lily Zhang, Shelly T Karuna, Philip Andrew, Michal Juraska, Joshua A Weiner, Heather Angier, Evgenii Morgan, Yasmin Azzam, Edith Swann, Srilatha Edupuganti, Nyaradzo M Mgodi, Margaret E Ackerman, Deborah Donnell, Lucio Gama, Peter L Anderson, Richard A Koup, John Hural, Myron S Cohen, Lawrence Corey, M Juliana McElrath, Peter B Gilbert, Maria P Lemos
Adults on pre-exposure prophylaxis (tenofovir-emtricitabine) have faster clearance of anti-HIV monoclonal antibody VRC01. Nature communications 14 (1) (2023)
Andrew P Hederman, Harini Natarajan, Leo Heyndrickx, Kevin K Ariën, Joshua A Weiner, Peter F Wright, Evan M Bloch, Aaron A R Tobian, Andrew D Redd, Joel N Blankson, Amihai Rottenstreich, Gila Zarbiv, Dana Wolf, Tessa Goetghebuer, Arnaud Marchant, Margaret E Ackerman
SARS-CoV-2 vaccination elicits broad and potent antibody effector functions to variants of concern in vulnerable populations. Nature communications 14 (1) (2023)
Benjamin S Goldberg, David A Spencer, Shilpi Pandey, Tracy Ordonez, Philip Barnette, Yun Yu, Lina Gao, Jeremy Dufloo, Timothee Bruel, Olivier Schwartz, Margaret E Ackerman, Ann J Hessell
Complement contributes to antibody-mediated protection against repeated SHIV challenge. Proceedings of the National Academy of Sciences of the United States of America 120 (20) (2023)
Benjamin S Goldberg, David A Spencer, Shilpi Pandey, Tracy Ordonez, Philip Barnette, Yun Yu, Lina Gao, Jeremy Dufloo, Timothee Bruel, Olivier Schwartz, Margaret E Ackerman, Ann J Hessell
Complement contributes to antibody-mediated protection against repeated SHIV challenge. Proceedings of the National Academy of Sciences of the United States of America 120 (20) (2023)
Roger L Shapiro, Globahan Ajibola, Kenneth Maswabi, Michael Hughes, Bryan S Nelson, Aischa Niesar, Molly Pretorius Holme, Kathleen M Powis, Maureen Sakoi-Mosetlhi, Oganne Batlang, Sikhulile Moyo, Terence Mohammed, Comfort Maphorisa, Kara Bennett, Zixin Hu, Francoise Giguel, Jacqueline D Reeves, Michael A Reeves, Ce Gao, Xu G Yu, Margaret E Ackerman, Adrian B McDermott, Marlene Cooper, Marina Caskey, Lucio Gama, Patrick Jean-Philippe, Dwight E Yin, Edmund V Capparelli, Shahin Lockman, Joseph Makhema, Daniel R Kuritzkes, Mathias D Lichterfeld
Broadly neutralizing antibody treatment maintained HIV suppression in children with favorable reservoir characteristics in Botswana. Science translational medicine 15 (703) (2023)
Matthew D Slein, Iara M Backes, Callaghan R Garland, Natasha S Kelkar, David A Leib, Margaret E Ackerman
Antibody effector functions are required for broad and potent protection of neonates from herpes simplex virus infection. bioRxiv : the preprint server for biology (2023)
Yvonne J Rosenberg, Tracy Ordonez, Urjeet S Khanwalkar, Philip Barnette, Shilpi Pandey, Iara M Backes, Claire E Otero, Benjamin S Goldberg, Andrew R Crowley, David A Leib, Mariya B Shapiro, Xiaoming Jiang, Lori A Urban, Jonathan Lees, Ann J Hessell, Sallie Permar, Nancy L Haigwood, Margaret E Ackerman
Evidence for the Role of a Second Fc-Binding Receptor in Placental IgG Transfer in Nonhuman Primates. mBio (2023)
Andrew R Crowley, Matthew R Mehlenbacher, Mohammad M Sajadi, Anthony L DeVico, George K Lewis, Margaret E Ackerman
Evidence of variable human Fcγ receptor-Fc affinities across differentially-complexed IgG. mAbs 15 (1) (2023)
Benjamin S Goldberg, David A Spencer, Shilpi Pandey, Tracy Ordonez, Philip Barnette, Yun Yu, Lina Gao, Jeremy Dufloo, Timothee Bruel, Olivier Schwartz, Margaret E Ackerman, Ann J Hessell
Complement contributes to antibody-mediated protection against repeated SHIV challenge. Proceedings of the National Academy of Sciences of the United States of America 120 (20) (2023)
Benjamin S Goldberg, David A Spencer, Shilpi Pandey, Tracy Ordonez, Philip Barnette, Yun Yu, Lina Gao, Jeremy Dufloo, Timothee Bruel, Olivier Schwartz, Margaret E Ackerman, Ann J Hessell
Complement contributes to antibody-mediated protection against repeated SHIV challenge. Proceedings of the National Academy of Sciences of the United States of America 120 (20) (2023)
Benjamin S Goldberg, David A Spencer, Shilpi Pandey, Tracy Ordonez, Philip Barnette, Yun Yu, Lina Gao, Jeremy Dufloo, Timothee Bruel, Olivier Schwartz, Margaret E Ackerman, Ann J Hessell
Complement contributes to antibody-mediated protection against repeated SHIV challenge. Proceedings of the National Academy of Sciences of the United States of America 120 (20) (2023)
Benjamin S Goldberg, David A Spencer, Shilpi Pandey, Tracy Ordonez, Philip Barnette, Yun Yu, Lina Gao, Jeremy Dufloo, Timothee Bruel, Olivier Schwartz, Margaret E Ackerman, Ann J Hessell
Complement contributes to antibody-mediated protection against repeated SHIV challenge. Proceedings of the National Academy of Sciences of the United States of America 120 (20) (2023)
Jacqueline M Brady, Meredith Phelps, Scott W MacDonald, Evan C Lam, Adam Nitido, Dylan Parsons, Christine L Boutros, Cailin E Deal, Wilfredo F Garcia-Beltran, Serah Tanno, Harini Natarajan, Margaret E Ackerman, Vladimir D Vrbanac, Alejandro B Balazs
Antibody-mediated prevention of vaginal HIV transmission is dictated by IgG subclass in humanized mice. Science translational medicine 14 (655) (2022)
Chengzi I Kaku, Elizabeth R Champney, Johan Normark, Marina García, Carl E Johnson, Clas Ahlm, Wanda Christ, Mrunal Sakharkar, Margaret E Ackerman, Jonas Klingström, Mattias N E Forsell, Laura M Walker
Broad anti-SARS-CoV-2 antibody immunity induced by heterologous ChAdOx1/mRNA-1273 vaccination. Science (New York, N.Y.) 375 (6584) (2022)
Andrew R Crowley, Simone I Richardson, Marina Tuyishime, Madeleine Jennewein, Meredith J Bailey, Jiwon Lee, Galit Alter, Guido Ferrari, Lynn Morris, Margaret E Ackerman
Functional consequences of allotypic polymorphisms in human immunoglobulin G subclasses. Immunogenetics (2022)
Shiwei Xu, Margaret C Carpenter, Rachel L Spreng, Scott D Neidich, Sharanya Sarkar, DeAnna Tenney, Derrick Goodman, Sheetal Sawant, Shalini Jha, Brooke Dunn, M Juliana McElrath, Valerie Bekker, Sarah V Mudrak, Robin Flinko, George Kenneth Lewis, Guido Ferrari, Georgia D Tomaras, Xiaoying Shen, Margaret E Ackerman
Impact of adjuvants on the biophysical and functional characteristics of HIV vaccine-elicited antibodies in humans. NPJ vaccines 7 (1) (2022)
Andrew P Hederman, Harini Natarajan, Joshua A Wiener, Peter F Wright, Evan M Bloch, Aaron A R Tobian, Andrew D Redd, Joel N Blankson, Amihai Rottenstreich, Gila Zarbiv, Dana Wolf, Tessa Goetghebuer, Arnaud Marchant, Margaret E Ackerman
SARS-CoV-2 mRNA vaccination elicits broad and potent Fc effector functions to VOCs in vulnerable populations. medRxiv : the preprint server for health sciences (2022)
Sean A Taylor, Shilpee Sharma, Christopher A L Remmel, Beth Holder, Christine E Jones, Arnaud Marchant, Margaret E Ackerman
HIV-Associated Alterations of the Biophysical Features of Maternal Antibodies Correlate With Their Reduced Transfer Across the Placenta. The Journal of infectious diseases 226 (8) (2022)
Yaozong Chen, Lulu Sun, Irfan Ullah, Guillaume Beaudoin-Bussières, Sai Priya Anand, Andrew P Hederman, William D Tolbert, Rebekah Sherburn, Dung N Nguyen, Lorie Marchitto, Shilei Ding, Di Wu, Yuhong Luo, Suneetha Gottumukkala, Sean Moran, Priti Kumar, Grzegorz Piszczek, Walther Mothes, Margaret E Ackerman, Andrés Finzi, Pradeep D Uchil, Frank J Gonzalez, Marzena E Pazgier
Engineered ACE2-Fc counters murine lethal SARS-CoV-2 infection through direct neutralization and Fc-effector activities. Science advances 8 (28) (2022)
Andrew R Crowley, Harini Natarajan, Andrew P Hederman, Carly A Bobak, Joshua A Weiner, Wendy Wieland-Alter, Jiwon Lee, Evan M Bloch, Aaron A R Tobian, Andrew D Redd, Joel N Blankson, Dana Wolf, Tessa Goetghebuer, Arnaud Marchant, Ruth I Connor, Peter F Wright, Margaret E Ackerman
Boosting of cross-reactive antibodies to endemic coronaviruses by SARS-CoV-2 infection but not vaccination with stabilized spike. eLife 11 (2022)
Iara M Backes, Brook K Byrd, Matthew D Slein, Chaya D Patel, Sean A Taylor, Callaghan R Garland, Scott W MacDonald, Alejandro B Balazs, Scott C Davis, Margaret E Ackerman, David A Leib
Maternally transferred mAbs protect neonatal mice from HSV-induced mortality and morbidity. The Journal of experimental medicine 219 (12) (2022)
David A Spencer, Benjamin S Goldberg, Shilpi Pandey, Tracy Ordonez, Jeremy Dufloo, Philip Barnette, William F Sutton, Heidi Henderson, Rebecca Agnor, Lina Gao, Timothee Bruel, Olivier Schwartz, Nancy L Haigwood, Margaret E Ackerman, Ann J Hessell
Phagocytosis by an HIV antibody is associated with reduced viremia irrespective of enhanced complement lysis. Nature communications 13 (1) (2022)
Hao D Cheng, Karen G Dowell, Chris Bailey-Kellogg, Brittany A Goods, J Christopher Love, Guido Ferrari, Galit Alter, Johannes Gach, Donald N Forthal, George K Lewis, Kelli Greene, Hongmei Gao, David C Montefiori, Margaret E Ackerman
Diverse antiviral IgG effector activities are predicted by unique biophysical antibody features. Retrovirology 18 (1) (2021)
Todd J Suscovich, Jonathan K Fallon, Jishnu Das, Allison R Demas, Jonathan Crain, Caitlyn H Linde, Ashlin R Michell, Harini Natarajan, Claudia P Arevalo, Thomas Broge, Thomas Linnekin, Viraj Kulkarni, Richard Lu, Matthew D Slein, Corinne Luedemann, Meghan Marquette, Sandra March, Joshua A Weiner, Scott Gregory, Margherita Coccia, Yevel Flores-Garcia, Fidel Zavala, Margaret E Ackerman, Elke S Bergmann-Leitner, Jenny Hendriks, Jerald Sadoff, Sheetij Dutta, Sangeeta N Bhatia, Douglas A Lauffenburger, Erik Jongert, Ulrike Wille-Reece, Galit Alter
Mapping functional humoral correlates of protection against malaria challenge following RTS,S/AS01 vaccination. Science translational medicine 12 (553) (2021)
David A Spencer, Delphine C Malherbe, Néstor Vázquez Bernat, Monika Ádori, Benjamin S Goldberg, Nicholas Dambrauskas, Heidi Henderson, Shilpi Pandey, Tracy Cheever, Philip Barnette, William F Sutton, Margaret E Ackerman, James J Kobie, D Noah Sather, Gunilla B Karlsson Hedestam, Nancy L Haigwood, Ann J Hessell
Polyfunctional Tier 2-Neutralizing Antibodies Cloned following HIV-1 Env Macaque Immunization Mirror Native Antibodies in a Human Donor. Journal of immunology (Baltimore, Md. : 1950) 206 (5) (2021)
Savannah E Butler, Rachel A Brog, Cheryl H Chang, Charles L Sentman, Yina H Huang, Margaret E Ackerman
Engineering a natural ligand-based CAR: directed evolution of the stress-receptor NKp30. Cancer immunology, immunotherapy : CII (2021)
Harini Natarajan, Andrew R Crowley, Savannah E Butler, Shiwei Xu, Joshua A Weiner, Evan M Bloch, Kirsten Littlefield, Wendy Wieland-Alter, Ruth I Connor, Peter F Wright, Sarah E Benner, Tania S Bonny, Oliver Laeyendecker, David Sullivan, Shmuel Shoham, Thomas C Quinn, H Benjamin Larman, Arturo Casadevall, Andrew S Pekosz, Andrew D Redd, Aaron A R Tobian, Margaret E Ackerman
Markers of Polyfunctional SARS-CoV-2 Antibodies in Convalescent Plasma. mBio 12 (2) (2021)
Benjamin S Goldberg, Chengzi I Kaku, Jérémy Dufloo, Timothée Bruel, Olivier Schwartz, David A Spencer, Ann J Hessell, Margaret E Ackerman
Revisiting an IgG Fc Loss-of-Function Experiment: the Role of Complement in HIV Broadly Neutralizing Antibody b12 Activity. mBio 12 (5) (2021)
Chaya D Patel, Iara M Backes, Sean A Taylor, Yike Jiang, Arnaud Marchant, Jean M Pesola, Donald M Coen, David M Knipe, Margaret E Ackerman, David A Leib
Maternal immunization confers protection against neonatal herpes simplex mortality and behavioral morbidity. Science translational medicine 11 (487) (2020)
Mangaiarkarasi Asokan, Joana Dias, Cuiping Liu, Anna Maximova, Keenan Ernste, Amarendra Pegu, Krisha McKee, Wei Shi, Xuejun Chen, Cassandra Almasri, Wanwisa Promsote, David R Ambrozak, Lucio Gama, Jianfei Hu, Daniel C Douek, John-Paul Todd, Jeffrey D Lifson, Slim Fourati, Rafick P Sekaly, Andrew R Crowley, Margaret E Ackerman, Sung Hee Ko, Divya Kilam, Eli A Boritz, Laura E Liao, Katharine Best, Alan S Perelson, John R Mascola, Richard A Koup
Fc-mediated effector function contributes to the in vivo antiviral effect of an HIV neutralizing antibody. Proceedings of the National Academy of Sciences of the United States of America 117 (31) (2020)
Benjamin S Goldberg, Margaret E Ackerman
Antibody-mediated complement activation in pathology and protection. Immunology and cell biology 98 (4) (2020)
Jishnu Das, Anush Devadhasan, Caitlyn H Linde, Tom Broge, Jessica Sassic, Max Mangano, Sean O'Keefe, Todd J Suscovich, Hendrik Streeck, Alivelu Irrinki, Christopher W Pohlmeyer, Gundula Min-Oo, Shu Lin, Joshua A Weiner, Thomas Cihlar, Margaret E Ackerman, Boris Julg, Steven G Deeks, Douglas A Lauffenburger, Galit Alter
Mining for humoral correlates of HIV control and latent reservoir size. PLoS pathogens 16 (10) (2020)
Kier Om, Dominic Paquin-Proulx, Maria Montero, Kristina Peachman, Xiaoying Shen, Lindsay Wieczorek, Zoltan Beck, Joshua A Weiner, Dohoon Kim, Yifan Li, Thembi Mdluli, Zhanna Shubin, Christopher Bryant, Vishakha Sharma, Andrey Tokarev, Peter Dawson, Yohann White, Oliver Appelbe, Nichole R Klatt, Sodsai Tovanabutra, Jacob D Estes, Gary R Matyas, Guido Ferrari, Carl R Alving, Georgia D Tomaras, Margaret E Ackerman, Nelson L Michael, Merlin L Robb, Victoria Polonis, Morgane Rolland, Michael A Eller, Mangala Rao, Diane L Bolton
Adjuvanted HIV-1 vaccine promotes antibody-dependent phagocytic responses and protects against heterologous SHIV challenge. PLoS pathogens 16 (9) (2020)
Thach H Chu, Andrew R Crowley, Iara Backes, Cheryl Chang, Matthew Zirui Tay, Thomas Broge, Marina Tuyishime, Guido Ferrari, Michael S Seaman, Simone I Richardson, Georgia D Tomaras, Galit Alter, David Leib, Margaret E Ackerman
Hinge length contributes to the phagocytic activity of HIV-specific IgG1 and IgG3 antibodies. PLoS pathogens 16 (2) (2020)
Giuseppe Lofano, Matthew J Gorman, Ashraf S Yousif, Wen Han Yu, Julie M Fox, Anne-Sophie Dugast, Margaret E Ackerman, Todd J Suscovich, Joshua A Weiner, Dan H Barouch, Hendrik Streeck, Susan J Little, Davey Smith, Douglas D Richman, Douglas A Lauffenburger, Bruce D Walker, Michael S. Diamond, Galit Alter
Antigen-specific antibody Fc glycosylation enhances humoral immunity via the recruitment of complement. Science immunology 3 (26) (2019)
Srivamshi Pittala, Kenneth Bagley, Jennifer A Schwartz, Eric P Brown, Joshua A Weiner, Ilia J Prado, Wenlei Zhang, Rong Xu, Ayuko Ota-Setlik, Ranajit Pal, Xiaoying Shen, Charles Beck, Guido Ferrari, George Kenneth Lewis, Celia C LaBranche, David C Montefiori, Georgia D Tomaras, Galit Alter, Mario Roederer, Timothy R Fouts, Margaret E Ackerman, Chris Bailey-Kellogg
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