Stephen Neidle (S Neidle)

Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 26

Top Topics

Amyotrophic Lateral Sclerosis

Gene Expression

Top Venues

Molecules (Basel, Switzerland)

Nucleic acids research

Scientific reports

EMBO molecular medicine

This page only lists publications with an associated author ORCID identifier.

Publications

Liliya A Yatsunyk, Stephen Neidle
On Water Arrangements in Right- and Left-Handed DNA Structures. Molecules (Basel, Switzerland) 29 (2) (2024)
Shan-Meng Lin, Hsiang-Ti Huang, Pei-Ju Fang, Chi-Fon Chang, Roshan Satange, Chung-Ke Chang, Shan-Ho Chou, Stephen Neidle, Ming-Hon Hou
Structural basis of water-mediated cis Watson-Crick/Hoogsteen base-pair formation in non-CpG methylation. Nucleic acids research (2024)
Stephen Neidle
A Phenotypic Approach to the Discovery of Potent G-Quadruplex Targeted Drugs. Molecules (Basel, Switzerland) 29 (15) (2024)
Shan-Meng Lin, Hsiang-Ti Huang, Pei-Ju Fang, Chi-Fon Chang, Roshan Satange, Chung-Ke Chang, Shan-Ho Chou, Stephen Neidle, Ming-Hon Hou
Structural basis of water-mediated cis Watson-Crick/Hoogsteen base-pair formation in non-CpG methylation. Nucleic acids research 52 (14) (2024)
Ahmed Abdullah Ahmed, Shuang Chen, Maria Roman-Escorza, Richard Angell, Sally Oxenford, Matthew McConville, Naomi Barton, Mihiro Sunose, Dan Neidle, Shozeb M Haider, Tariq Arshad, Stephen Neidle
Structure-activity relationships for the G-quadruplex-targeting experimental drug QN-302 and two analogues probed with comparative transcriptome profiling and molecular modeling. Scientific reports 14 (1) (2024)
Shan-Meng Lin, Hsiang-Ti Huang, Pei-Ju Fang, Chi-Fon Chang, Roshan Satange, Chung-Ke Chang, Shan-Ho Chou, Stephen Neidle, Ming-Hon Hou
Structural basis of water-mediated cis Watson-Crick/Hoogsteen base-pair formation in non-CpG methylation. Nucleic acids research 52 (14) (2024)
Liliya A Yatsunyk, Stephen Neidle
On Water Arrangements in Right- and Left-Handed DNA Structures. Molecules (Basel, Switzerland) 29 (2) (2024)
Ahmed Abdullah Ahmed, Shuang Chen, Maria Roman-Escorza, Richard Angell, Sally Oxenford, Matthew McConville, Naomi Barton, Mihiro Sunose, Dan Neidle, Shozeb M Haider, Tariq Arshad, Stephen Neidle
Structure-activity relationships for the G-quadruplex-targeting experimental drug QN-302 and two analogues probed with comparative transcriptome profiling and molecular modeling. Scientific reports 14 (1) (2024)
Stephen Neidle
A Phenotypic Approach to the Discovery of Potent G-Quadruplex Targeted Drugs. Molecules (Basel, Switzerland) 29 (15) (2024)
Stephen Neidle
A Phenotypic Approach to the Discovery of Potent G-Quadruplex Targeted Drugs. Molecules (Basel, Switzerland) 29 (15) (2024)
Liliya A Yatsunyk, Stephen Neidle
On Water Arrangements in Right- and Left-Handed DNA Structures. Molecules (Basel, Switzerland) 29 (2) (2024)
Ahmed Abdullah Ahmed, Shuang Chen, Maria Roman-Escorza, Richard Angell, Sally Oxenford, Matthew McConville, Naomi Barton, Mihiro Sunose, Dan Neidle, Shozeb M Haider, Tariq Arshad, Stephen Neidle
Structure-activity relationships for the G-quadruplex-targeting experimental drug QN-302 and two analogues probed with comparative transcriptome profiling and molecular modeling. Scientific reports 14 (1) (2024)
Liliya A Yatsunyk, Stephen Neidle
On Water Arrangements in Right- and Left-Handed DNA Structures. Molecules (Basel, Switzerland) 29 (2) (2024)
Ahmed Abdullah Ahmed, Shuang Chen, Maria Roman-Escorza, Richard Angell, Sally Oxenford, Matthew McConville, Naomi Barton, Mihiro Sunose, Dan Neidle, Shozeb M Haider, Tariq Arshad, Stephen Neidle
Structure-activity relationships for the G-quadruplex-targeting experimental drug QN-302 and two analogues probed with comparative transcriptome profiling and molecular modeling. Scientific reports 14 (1) (2024)
Stephen Neidle
On the origins of the conflict between Rosalind Franklin and Maurice Wilkins. Nature reviews. Chemistry (2023)
Effrosyni Alexandrou, Dilek Guneri, Stephen Neidle, Zoë A E Waller
QN-302 demonstrates opposing effects between i-motif and G-quadruplex DNA structures in the promoter of the S100P gene. Organic & biomolecular chemistry (2023)
Ahmed Abdullah Ahmed, William Greenhalf, Daniel H Palmer, Nicole Williams, Jenny Worthington, Tariq Arshad, Shozeb Haider, Effrosyni Alexandrou, Dilek Guneri, Zoe A E Waller, Stephen Neidle
The Potent G-Quadruplex-Binding Compound QN-302 Downregulates S100P Gene Expression in Cells and in an In Vivo Model of Pancreatic Cancer. Molecules (Basel, Switzerland) 28 (6) (2023)
Roshan Satange, Chih-Chun Chang, Long-Yuan Li, Sheng-Hao Lin, Stephen Neidle, Ming-Hon Hou
Synergistic binding of actinomycin D and echinomycin to DNA mismatch sites and their combined anti-tumour effects. Nucleic acids research (2023)
Ahmed Abdullah Ahmed, William Greenhalf, Daniel H Palmer, Nicole Williams, Jenny Worthington, Tariq Arshad, Shozeb Haider, Effrosyni Alexandrou, Dilek Guneri, Zoe A E Waller, Stephen Neidle
The Potent G-Quadruplex-Binding Compound QN-302 Downregulates S100P Gene Expression in Cells and in an In Vivo Model of Pancreatic Cancer. Molecules (Basel, Switzerland) 28 (6) (2023)
Ahmed Abdullah Ahmed, William Greenhalf, Daniel H Palmer, Nicole Williams, Jenny Worthington, Tariq Arshad, Shozeb Haider, Effrosyni Alexandrou, Dilek Guneri, Zoe A E Waller, Stephen Neidle
The Potent G-Quadruplex-Binding Compound QN-302 Downregulates S100P Gene Expression in Cells and in an In Vivo Model of Pancreatic Cancer. Molecules (Basel, Switzerland) 28 (6) (2023)
Roshan Satange, Shih-Hao Kao, Ching-Ming Chien, Shan-Ho Chou, Chi-Chien Lin, Stephen Neidle, Ming-Hon Hou
Staggered intercalation of DNA duplexes with base-pair modulation by two distinct drug molecules induces asymmetric backbone twisting and structure polymorphism. Nucleic acids research 50 (15) (2022)
Cyong-Ru Jhan, Roshan Satange, Shun-Ching Wang, Jing-Yi Zeng, Yih-Chern Horng, Peng Jin, Stephen Neidle, Ming-Hon Hou
Targeting the ALS/FTD-associated A-DNA kink with anthracene-based metal complex causes DNA backbone straightening and groove contraction. Nucleic acids research 49 (16) (2021)
Ahmed Abdullah Ahmed, Chiara Marchetti, Stephan A Ohnmacht, Stephen Neidle
A G-quadruplex-binding compound shows potent activity in human gemcitabine-resistant pancreatic cancer cells. Scientific reports 10 (1) (2020)
Roberto Simone, Rubika Balendra, Thomas G Moens, Elisavet Preza, Katherine M Wilson, Amanda Heslegrave, Nathan S Woodling, Teresa Niccoli, Javier Gilbert-Jaramillo, Samir Abdelkarim, Emma L Clayton, Mica Clarke, Marie-Therese Konrad, Andrew J Nicoll, Jamie S Mitchell, Andrea Calvo, Adriano Chio, Henry Houlden, James M Polke, Mohamed A Ismail, Chad E Stephens, Tam Vo, Abdelbasset A Farahat, W David Wilson, David W Boykin, Henrik Zetterberg, Linda Partridge, Selina Wray, Gary Parkinson, Stephen Neidle, Rickie Patani, Pietro Fratta, Adrian M Isaacs
G-quadruplex-binding small molecules ameliorate C9orf72 FTD/ALS pathology in vitro and in vivo. EMBO molecular medicine 10 (1) (2019)
Chiara Marchetti, Katherine G Zyner, Stephan A Ohnmacht, Mathew Robson, Shozeb M Haider, Jennifer P Morton, Giovanni Marsico, Tam Vo, Sarah Laughlin-Toth, Ahmed A Ahmed, Gloria Di Vita, Ingrida Pazitna, Mekala Gunaratnam, Rachael J Besser, Ana C G Andrade, Seckou Diocou, Jeremy A Pike, David Tannahill, R Barbara Pedley, T R Jeffry Evans, W David Wilson, Samantha Kendrick, Stephen Neidle
Targeting Multiple Effector Pathways in Pancreatic Ductal Adenocarcinoma with a G-Quadruplex-Binding Small Molecule. Journal of medicinal chemistry 61 (6) (2018)
R Mizuta, J M Devos, J Webster, W L Ling, Theyencheri Narayanan, Adam R Round, D Munnur, E Mossou, Abdelbasset A Farahat, David W Boykin, W David Wilson, Stephen Neidle, Ralf Schweins, Patrice Rannou, M Haertlein, V Trevor Forsyth, Edward P Mitchell
Dynamic self-assembly of DNA minor groove-binding ligand DB921 into nanotubes triggered by an alkali halide. Nanoscale 10 (12) (2018)