Stephen S Hecht

Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 56

Top Topics

Liquid Chromatography

Mass Spectrometry

Top Venues

Chemical research in toxicology

Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology

This page only lists publications with an associated author ORCID identifier.

Publications

Sharon E Murphy, Cherie Guillermo, Nicole M Thomson, Steven G Carmella, Milo Wittmann, Melinda C Aldrich, Qiuyin Cai, Shannon M Sullivan, Daniel O Stram, Loic Le Marchand, Stephen S Hecht, William J Blot, Sung-Shim L Park
Association of Urinary Biomarkers of Tobacco Exposure with Lung Cancer Risk in African American and White Cigarette Smokers in the Southern Community Cohort Study. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 33 (8) (2024)
Lisa A Peterson, Stephen B Stanfill, Stephen S Hecht
An update on the formation in tobacco, toxicity and carcinogenicity of N'-nitrosonornicotine and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone. Carcinogenesis 45 (5) (2024)
Lisa A Peterson, Stephen B Stanfill, Stephen S Hecht
An update on the formation in tobacco, toxicity and carcinogenicity of N'-nitrosonornicotine and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone. Carcinogenesis 45 (5) (2024)
Lisa A Peterson, Stephen B Stanfill, Stephen S Hecht
An update on the formation in tobacco, toxicity and carcinogenicity of N'-nitrosonornicotine and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone. Carcinogenesis 45 (5) (2024)
Sharon E Murphy, Cherie Guillermo, Nicole M Thomson, Steven G Carmella, Milo Wittmann, Melinda C Aldrich, Qiuyin Cai, Shannon M Sullivan, Daniel O Stram, Loic Le Marchand, Stephen S Hecht, William J Blot, Sung-Shim L Park
Association of urinary biomarkers of tobacco exposure with lung cancer risk in African American and White cigarette smokers in the Southern Community Cohort Study. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology (2024)
Yupeng Li, Mei Kuen Tang, Steven G Carmella, Calvin P Peters, Jerry D Cohen, Adrian D Hegeman, Stephen S Hecht
Hydroponic Growth of [ 13 C]-Labeled Tobacco for DNA Damage Studies in Cigarette Smokers. Journal of agricultural and food chemistry 72 (30) (2024)
Yupeng Li, Mei Kuen Tang, Steven G Carmella, Calvin P Peters, Jerry D Cohen, Adrian D Hegeman, Stephen S Hecht
Hydroponic Growth of [ 13 C]-Labeled Tobacco for DNA Damage Studies in Cigarette Smokers. Journal of agricultural and food chemistry (2024)
Lisa A Peterson, Stephen B Stanfill, Stephen S Hecht
An Update on the Formation in Tobacco, Toxicity, and Carcinogenicity of N'-Nitrosonornicotine and 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone. Carcinogenesis (2024)
Sharon E Murphy, Cherie Guillermo, Nicole M Thomson, Steven G Carmella, Milo Wittmann, Melinda C Aldrich, Qiuyin Cai, Shannon M Sullivan, Daniel O Stram, Loic Le Marchand, Stephen S Hecht, William J Blot, Sung-Shim L Park
Association of urinary biomarkers of tobacco exposure with lung cancer risk in African American and White cigarette smokers in the Southern Community Cohort Study. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology (2024)
Lisa A Peterson, Stephen B Stanfill, Stephen S Hecht
An update on the formation in tobacco, toxicity and carcinogenicity of N'-nitrosonornicotine and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone. Carcinogenesis 45 (5) (2024)
Michael Korenjak, Nuri Alpay Temiz, Stéphane Keita, Bérénice Chavanel, Claire Renard, Cécilia Sirand, Vincent Cahais, Tanguy Mayel, Karin R Vevang, Foster C Jacobs, Jiehong Guo, William E Smith, Marissa K Oram, Alexandru-Flaviu Tăbăran, Ozan Ahlat, Ingrid Cornax, M Gerard O'Sullivan, Samrat Das, Shuvro Prokash Nandi, Yuhe Cheng, Ludmil B Alexandrov, Silvia Balbo, Stephen S Hecht, Sergey Senkin, Francois Virard, Lisa A Peterson, Jiri Zavadil
Human cancer genomes harbor the mutational signature of tobacco-specific nitrosamines NNN and NNK. bioRxiv : the preprint server for biology (2024)
Sharon E Murphy, Cherie Guillermo, Nicole M Thomson, Steven G Carmella, Milo Wittmann, Melinda C Aldrich, Qiuyin Cai, Shannon M Sullivan, Daniel O Stram, Loic Le Marchand, Stephen S Hecht, William J Blot, Sung-Shim L Park
Association of Urinary Biomarkers of Tobacco Exposure with Lung Cancer Risk in African American and White Cigarette Smokers in the Southern Community Cohort Study. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 33 (8) (2024)
Guang Cheng, Jiehong Guo, Renwei Wang, Jian-Min Yuan, Silvia Balbo, Stephen S Hecht
Quantitation by Liquid Chromatography-Nanoelectrospray Ionization-High-Resolution Tandem Mass Spectrometry of Multiple DNA Adducts Related to Cigarette Smoking in Oral Cells in the Shanghai Cohort Study. Chemical research in toxicology 36 (2) (2023)
Prakash C Gupta, Stephen S Hecht
Special Issue on Tobacco: Chemistry, Mechanisms, Biomarkers and Disease Prevention. Chemical research in toxicology 36 (4) (2023)
Yupeng Li, Romel P Dator, Laura A Maertens, Silvia Balbo, Stephen S Hecht
Mass Spectrometry-Based Metabolic Profiling of Urinary Metabolites of N '-Nitrosonornicotine (NNN) in the Rat. Chemical research in toxicology (2023)
Guang Cheng, Jiehong Guo, Renwei Wang, Jian-Min Yuan, Silvia Balbo, Stephen S Hecht
Quantitation by Liquid Chromatography-Nanoelectrospray Ionization-High-Resolution Tandem Mass Spectrometry of Multiple DNA Adducts Related to Cigarette Smoking in Oral Cells in the Shanghai Cohort Study. Chemical research in toxicology 36 (2) (2023)
Guang Cheng, Jiehong Guo, Renwei Wang, Jian-Min Yuan, Silvia Balbo, Stephen S Hecht
Quantitation by Liquid Chromatography-Nanoelectrospray Ionization-High-Resolution Tandem Mass Spectrometry of Multiple DNA Adducts Related to Cigarette Smoking in Oral Cells in the Shanghai Cohort Study. Chemical research in toxicology (2023)
Chris H Wendt, Russell P Bowler, Connor Demorest, Annette Hastie, Wassim W Labaki, Menglan Chen, Steven G Carmella, Stephen S Hecht
Levels of Urinary Mercapturic Acids of Acrolein, Methacrolein, Crotonaldehyde, and Methyl Vinyl Ketone in Relationship to Chronic Obstructive Pulmonary Disease in Cigarette Smokers of the Subpopulations and Intermediate Outcome Measures in COPD Study (SPIROMICS). Chemical research in toxicology (2023)
Guang Cheng, Jiehong Guo, Renwei Wang, Jian-Min Yuan, Silvia Balbo, Stephen S Hecht
Quantitation by Liquid Chromatography-Nanoelectrospray Ionization-High-Resolution Tandem Mass Spectrometry of Multiple DNA Adducts Related to Cigarette Smoking in Oral Cells in the Shanghai Cohort Study. Chemical research in toxicology 36 (2) (2023)
Sungshim L Park, Loic Le Marchand, Guang Cheng, Silvia Balbo, Menglan Chen, Steven G Carmella, Nicole M Thomson, Younghan Lee, Yesha M Patel, Daniel O Stram, Joni Jensen, Dorothy K Hatsukami, Sharon E Murphy, Stephen S Hecht
Quantitation of DNA Adducts Resulting from Acrolein Exposure and Lipid Peroxidation in Oral Cells of Cigarette Smokers from Three Racial/Ethnic Groups with Differing Risks for Lung Cancer. Chemical research in toxicology 35 (10) (2022)
Yupeng Li, Stephen S Hecht
Mass Spectrometric Quantitation of N '-Nitrosonornicotine-1 N -oxide in the Urine of Cigarette Smokers and Smokeless Tobacco Users. Chemical research in toxicology 35 (9) (2022)
Melissa J L Bonorden, Steven G Carmella, Oliver T Ballinger, Jessica Williams, Irv Dorn, Hanna Vanderloo, Arpit Rao, Dorothy K Hatsukami, Stephen S Hecht
Preparation of a Beverage Containing Freeze-Dried Watercress for a Clinical Trial of Carcinogen and Toxicant Detoxification. Cancer prevention research (Philadelphia, Pa.) 15 (3) (2022)
June Feng, Connie S Sosnoff, John T Bernert, Benjamin C Blount, Yao Li, Arseima Y Del Valle-Pinero, Heather L Kimmel, Dana M van Bemmel, Sharyn M Rutt, Juan Crespo-Barreto, Nicolette Borek, Kathryn C Edwards, Ricky Alexander, Stephen Arnstein, Charlie Lawrence, Andrew Hyland, Maciej Lukasz Goniewicz, Imran Rehmani, Brittany Pine, Vincent Pagnotti, Erin Wade, James Sandlin, Zuzheng Luo, Sujeewa Piyankarage, Dorothy K Hatsukami, Stephen S Hecht, Kevin P Conway, Lanqing Wang
Urinary Nicotine Metabolites and Self-Reported Tobacco Use Among Adults in the Population Assessment of Tobacco and Health (PATH) Study, 2013-2014. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 24 (5) (2022)
Shannon M Sullivan, Sharon E Murphy, Daniel O Stram, Stephen S Hecht, Loic Le Marchand, Irina S Stepanov, Sung-Shim L Park
Association of urinary biomarkers of smoking-related toxicants with lung cancer incidence in smokers: The Multiethnic Cohort Study. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology (2022)
Qi Hu, Pramod Upadhyaya, Stephen S Hecht, F Zahra Aly, Zhiguang Huo, Chengguo Xing
Characterization of adductomic totality of NNK, (R)-NNAL and (S)-NNAL in A/J mice, and their correlations with distinct lung carcinogenicity. Carcinogenesis 43 (2) (2022)
Connie S Sosnoff, Kevin Caron, J Ricky Akins, Kristin Dortch, Ronald E Hunter, Brittany N Pine, June Feng, Benjamin C Blount, Yao Li, Dana M van Bemmel, Heather L Kimmel, Kathryn C Edwards, Maciej L Goniewicz, Dorothy K Hatsukami, B Rey de Castro, John T Bernert, Stephen Arnstein, Nicolette Borek, Ying Deng-Bryant, Elena Mishina, Charlie Lawrence, Andrew Hyland, Stephen S Hecht, Kevin P Conway, James L Pirkle, Lanqing Wang
Serum Concentrations of Cotinine and Trans-3'-Hydroxycotinine in US Adults: Results From Wave 1 (2013-2014) of the Population Assessment of Tobacco and Health Study. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 24 (5) (2022)
Stephen S Hecht, Prakash Chandra Gupta, Shana J Sturla, Yinsheng Wang
50 Years of Research on Tobacco-Specific Nitrosamines: A Virtual Collection of Emerging Knowledge of Chemical Toxicology of Tobacco and Nicotine Delivery Systems and Call for Contributions to a Landmark Special Issue. Chemical research in toxicology 35 (6) (2022)
Guang Cheng, Jiehong Guo, Steven G Carmella, Bruce Lindgren, Joshua Ikuemonisan, Brittany Niesen, Joni Jensen, Dorothy K Hatsukami, Silvia Balbo, Stephen S Hecht
Increased acrolein-DNA adducts in buccal brushings of e-cigarette users. Carcinogenesis 43 (5) (2022)
Ellen Meier, Nathan Rubin, Sarah S Dermody, Katelyn M Tessier, Stephen S Hecht, Sharon Murphy, Joni Jensen, Eric C Donny, Mustafa al'Absi, David Drobes, Joe Koopmeiners, Rachel L Denlinger-Apte, Jennifer W Tidey, Ryan Vandrey, Cole Thorne, Dorothy K Hatsukami
Immediate Switching to Reduced Nicotine Cigarettes in a U.S.-Based Sample: The Impact on Cannabis Use and Related Variables at 20 Weeks. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco (2022)
Stephen S Hecht, Dorothy K Hatsukami
Smokeless tobacco and cigarette smoking: chemical mechanisms and cancer prevention. Nature reviews. Cancer 22 (3) (2022)
Denise S Tevis, Andrew Willmore, Deepak Bhandari, Brett Bowman, Chloe Biren, Brandon M Kenwood, Peyton Jacob, Jia Liu, Kristina Bello, Stephen S Hecht, Steven G Carmella, Menglan Chen, Eric Gaudreau, Jean-François Bienvenu, Benjamin C Blount, Víctor R De Jesús
Large Differences in Urinary Benzene Metabolite S-Phenylmercapturic Acid Quantitation: A Comparison of Five LC-MS-MS Methods. Journal of analytical toxicology 45 (7) (2021)
Lisa A Peterson, Marissa K Oram, Monica Flavin, Donna Seabloom, William E Smith, M Gerard O'Sullivan, Karin R Vevang, Pramod Upadhyaya, Alessia Stornetta, Andrew C Floeder, Yen-Yi Ho, Lin Zhang, Stephen S Hecht, Silvia Balbo, Timothy S Wiedmann
Coexposure to Inhaled Aldehydes or Carbon Dioxide Enhances the Carcinogenic Properties of the Tobacco-Specific Nitrosamine 4-Methylnitrosamino-1-(3-pyridyl)-1-butanone in the A/J Mouse Lung. Chemical research in toxicology 34 (3) (2021)
Ellen Meier, Katelyn M Tessier, Xianghua Luo, Laura Dick, Nicole M Thomson, Stephen S Hecht, Steven G Carmella, Sharon Murphy, Dorothy K Hatsukami
Cigarette Smokers Versus Cannabis Smokers Versus Co-users of Cigarettes and Cannabis: A Pilot Study Examining Exposure to Toxicants. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco (2021)
Danielle M Smith, Carol Christensen, Dana van Bemmel, Nicolette Borek, Bridget Ambrose, Gladys Erives, Raymond Niaura, Kathryn C Edwards, Cassandra A Stanton, Benjamin C Blount, Lanqing Wang, Jun Feng, Jeffery M Jarrett, Cynthia D Ward, Dorothy Hatsukami, Stephen S Hecht, Heather L Kimmel, Mark Travers, Andrew Hyland, Maciej Lukasz Goniewicz
Exposure to Nicotine and Toxicants Among Dual Users of Tobacco Cigarettes and E-Cigarettes: Population Assessment of Tobacco and Health (PATH) Study, 2013-2014. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 23 (5) (2021)
Yupeng Li, Erik S Carlson, Adam T Zarth, Pramod Upadhyaya, Stephen S Hecht
Investigation of 2'-Deoxyadenosine-Derived Adducts Specifically Formed in Rat Liver and Lung DNA by N'-Nitrosonornicotine Metabolism. Chemical research in toxicology 34 (4) (2021)
Jiehong Guo, Joshua Ikuemonisan, Dorothy K Hatsukami, Stephen S Hecht
Liquid Chromatography-Nanoelectrospray Ionization-High-Resolution Tandem Mass Spectrometry Analysis of Apurinic/Apyrimidinic Sites in Oral Cell DNA of Cigarette Smokers, e-Cigarette Users, and Nonsmokers. Chemical research in toxicology (2021)
Yupeng Li, Stephen S Hecht
Identification of an N'-Nitrosonornicotine-Specific Deoxyadenosine Adduct in Rat Liver and Lung DNA. Chemical research in toxicology 34 (4) (2021)
Jiehong Guo, Haoqing Chen, Pramod Upadhyaya, Yingchun Zhao, Robert J Turesky, Stephen S Hecht
Mass Spectrometric Quantitation of Apurinic/Apyrimidinic Sites in Tissue DNA of Rats Exposed to Tobacco-Specific Nitrosamines and in Lung and Leukocyte DNA of Cigarette Smokers and Nonsmokers. Chemical research in toxicology 33 (9) (2020)
Qi Hu, Pedro Corral, Sreekanth C Narayanapillai, Pablo Leitzman, Pramod Upadhyaya, M Gerard O'Sullivan, Stephen S Hecht, Junxuan Lu, Chengguo Xing
Oral Dosing of Dihydromethysticin Ahead of Tobacco Carcinogen NNK Effectively Prevents Lung Tumorigenesis in A/J Mice. Chemical research in toxicology 33 (7) (2020)
Viviana Paiano, Laura Maertens, Valeria Guidolin, Jing Yang, Silvia Balbo, Stephen S Hecht
Quantitative Liquid Chromatography-Nanoelectrospray Ionization-High-Resolution Tandem Mass Spectrometry Analysis of Acrolein-DNA Adducts and Etheno-DNA Adducts in Oral Cells from Cigarette Smokers and Nonsmokers. Chemical research in toxicology 33 (8) (2020)
Menglan Chen, Steven G Carmella, Yupeng Li, Yingchun Zhao, Stephen S Hecht
Resolution and Quantitation of Mercapturic Acids Derived from Crotonaldehyde, Methacrolein, and Methyl Vinyl Ketone in the Urine of Smokers and Nonsmokers. Chemical research in toxicology 33 (2) (2020)
Nigel J Gooderham, Samuel M Cohen, Gerhard Eisenbrand, Shoji Fukushima, Frederick Peter Guengerich, Stephen S Hecht, Ivonne M C M Rietjens, Thomas J Rosol, Maria Bastaki, Matthew J Linman, Sean V Taylor
The safety evaluation of food flavoring substances: the role of genotoxicity studies. Critical reviews in toxicology 50 (1) (2020)
Menglan Chen, Steven G Carmella, Chistopher Sipe, Joni Jensen, Xianghua Luo, Chap T Le, Sharon E Murphy, Neal L Benowitz, F Joseph McClernon, Ryan Vandrey, Sharon S Allen, Rachel Denlinger-Apte, Paul M Cinciripini, Andrew A Strasser, Mustafa al'Absi, Jason D Robinson, Eric C Donny, Dorothy Hatsukami, Stephen S Hecht
Longitudinal stability in cigarette smokers of urinary biomarkers of exposure to the toxicants acrylonitrile and acrolein. PloS one 14 (1) (2019)
Steven G Carmella, Alisa K Heskin, Mei Kuen Tang, Joni Jensen, Xianghua Luo, Chap T Le, Sharon E Murphy, Neal L Benowitz, F Joseph McClernon, Ryan Vandrey, Sharon S Allen, Rachel Denlinger-Apte, Paul M Cinciripini, Andrew A Strasser, Mustafa al'Absi, Jason D Robinson, Eric C Donny, Dorothy K Hatsukami, Stephen S Hecht
Longitudinal stability in cigarette smokers of urinary eicosanoid biomarkers of oxidative damage and inflammation. PloS one 14 (4) (2019)
Jing Yang, Silvia Balbo, Peter W Villalta, Stephen S Hecht
Analysis of Acrolein-Derived 1, N2-Propanodeoxyguanosine Adducts in Human Lung DNA from Smokers and Nonsmokers. Chemical research in toxicology 32 (2) (2019)
Bin Ma, Irina Stepanov, Stephen S Hecht
Recent Studies on DNA Adducts Resulting from Human Exposure to Tobacco Smoke. Toxics 7 (1) (2019)
Yupeng Li, Bin Ma, Qing Cao, Silvia Balbo, Lijiao Zhao, Pramod Upadhyaya, Stephen S Hecht
Mass Spectrometric Quantitation of Pyridyloxobutyl DNA Phosphate Adducts in Rats Chronically Treated with N'-Nitrosonornicotine. Chemical research in toxicology 32 (4) (2019)
Erik S Carlson, Pramod Upadhyaya, Peter W Villalta, Bin Ma, Stephen S Hecht
Analysis and Identification of 2'-Deoxyadenosine-Derived Adducts in Lung and Liver DNA of F-344 Rats Treated with the Tobacco-Specific Carcinogen 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone and Enantiomers of its Metabolite 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol. Chemical research in toxicology 31 (5) (2018)
Stephen S Hecht
A New Editorial Team for CRT. Chemical research in toxicology 31 (1) (2017)
Bin Ma, Adam T Zarth, Erik S Carlson, Peter W Villalta, Pramod Upadhyaya, Irina S Stepanov, Stephen S Hecht
Methyl DNA Phosphate Adduct Formation in Rats Treated Chronically with 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone and Enantiomers of Its Metabolite 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol. Chemical research in toxicology 31 (1) (2017)
Stephen S Hecht
A Special Issue of CRT: Celebrating Volume 30. Chemical research in toxicology 30 (1) (2017)
Peter W Villalta, J Bradley Hochalter, Stephen S Hecht
Ultrasensitive High-Resolution Mass Spectrometric Analysis of a DNA Adduct of the Carcinogen Benzo[a]pyrene in Human Lung. Analytical chemistry 89 (23) (2017)
Manohar Puppala, Sreekanth C Narayanapillai, Pablo Leitzman, Haifeng Sun, Pramod Upadhyaya, M Gerard O'Sullivan, Stephen S Hecht, Chengguo Xing
Pilot in Vivo Structure-Activity Relationship of Dihydromethysticin in Blocking 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone-Induced O6-Methylguanine and Lung Tumor in A/J Mice. Journal of medicinal chemistry 60 (18) (2017)
Yesha M Patel, Sungshim L Park, Steven G Carmella, Viviana Paiano, Natalie Olvera, Daniel O Stram, Christopher A Haiman, Loic Le Marchand, Stephen S Hecht
Metabolites of the Polycyclic Aromatic Hydrocarbon Phenanthrene in the Urine of Cigarette Smokers from Five Ethnic Groups with Differing Risks for Lung Cancer. PloS one 11 (6) (2016)
Stephen S Hecht
Oral Cell DNA Adducts as Potential Biomarkers for Lung Cancer Susceptibility in Cigarette Smokers. Chemical research in toxicology 30 (1) (2016)
Erik S Carlson, Pramod Upadhyaya, Stephen S Hecht
Evaluation of Nitrosamide Formation in the Cytochrome P450-Mediated Metabolism of Tobacco-Specific Nitrosamines. Chemical research in toxicology 29 (12) (2016)