Tasuku Honjo (T Honjo)

Publication Activity (10 Years)

Years Active: 2017-2023
Publications (10 Years): 28

Top Topics

Diffuse Large B Cell Lymphoma

Top Venues

Proceedings of the National Academy of Sciences of the United States of America

Science immunology

Science translational medicine

The EMBO journal

This page only lists publications with an associated author ORCID identifier.

Publications

Maki Kobayashi, Hiroyuki Wakaguri, Masakazu Shimizu, Koichiro Higasa, Fumihiko Matsuda, Tasuku Honjo
Ago2 and a miRNA reduce Topoisomerase 1 for enhancing DNA cleavage in antibody diversification by activation-induced cytidine deaminase. Proceedings of the National Academy of Sciences of the United States of America 120 (18) (2023)
Maki Kobayashi, Hiroyuki Wakaguri, Masakazu Shimizu, Koichiro Higasa, Fumihiko Matsuda, Tasuku Honjo
Ago2 and a miRNA reduce Topoisomerase 1 for enhancing DNA cleavage in antibody diversification by activation-induced cytidine deaminase. Proceedings of the National Academy of Sciences of the United States of America 120 (18) (2023)
Maki Kobayashi, Hiroyuki Wakaguri, Masakazu Shimizu, Koichiro Higasa, Fumihiko Matsuda, Tasuku Honjo
Ago2 and a miRNA reduce Topoisomerase 1 for enhancing DNA cleavage in antibody diversification by activation-induced cytidine deaminase. Proceedings of the National Academy of Sciences of the United States of America 120 (18) (2023)
Kensuke Suzuki, Masaki Tajima, Yosuke Tokumaru, Yuya Oshiro, Satoshi Nagata, Haruhiko Kamada, Miho Kihara, Kohei Nakano, Tasuku Honjo, Akio Ohta
Anti-PD-1 antibodies recognizing the membrane-proximal region are PD-1 agonists that can down-regulate inflammatory diseases. Science immunology 8 (79) (2023)
Kenji Chamoto, Tomonori Yaguchi, Masaki Tajima, Tasuku Honjo
Insights from a 30-year journey: function, regulation and therapeutic modulation of PD1. Nature reviews. Immunology (2023)
Kensuke Suzuki, Masaki Tajima, Yosuke Tokumaru, Yuya Oshiro, Satoshi Nagata, Haruhiko Kamada, Miho Kihara, Kohei Nakano, Tasuku Honjo, Akio Ohta
Anti-PD-1 antibodies recognizing the membrane-proximal region are PD-1 agonists that can down-regulate inflammatory diseases. Science immunology 8 (79) (2023)
Kensuke Suzuki, Masaki Tajima, Yosuke Tokumaru, Yuya Oshiro, Satoshi Nagata, Haruhiko Kamada, Miho Kihara, Kohei Nakano, Tasuku Honjo, Akio Ohta
Anti-PD-1 antibodies recognizing the membrane-proximal region are PD-1 agonists that can down-regulate inflammatory diseases. Science immunology 8 (79) (2023)
Kensuke Suzuki, Masaki Tajima, Yosuke Tokumaru, Yuya Oshiro, Satoshi Nagata, Haruhiko Kamada, Miho Kihara, Kohei Nakano, Tasuku Honjo, Akio Ohta
Anti-PD-1 antibodies recognizing the membrane-proximal region are PD-1 agonists that can down-regulate inflammatory diseases. Science immunology 8 (79) (2023)
Maki Kobayashi, Hiroyuki Wakaguri, Masakazu Shimizu, Koichiro Higasa, Fumihiko Matsuda, Tasuku Honjo
Ago2 and a miRNA reduce Topoisomerase 1 for enhancing DNA cleavage in antibody diversification by activation-induced cytidine deaminase. Proceedings of the National Academy of Sciences of the United States of America 120 (18) (2023)
Kensuke Suzuki, Masaki Tajima, Yosuke Tokumaru, Yuya Oshiro, Satoshi Nagata, Haruhiko Kamada, Miho Kihara, Kohei Nakano, Tasuku Honjo, Akio Ohta
Anti-PD-1 antibodies recognizing the membrane-proximal region are PD-1 agonists that can down-regulate inflammatory diseases. Science immunology 8 (79) (2023)
Maki Kobayashi, Hiroyuki Wakaguri, Masakazu Shimizu, Koichiro Higasa, Fumihiko Matsuda, Tasuku Honjo
Ago2 and a miRNA reduce Topoisomerase 1 for enhancing DNA cleavage in antibody diversification by activation-induced cytidine deaminase. Proceedings of the National Academy of Sciences of the United States of America 120 (18) (2023)
Maki Kobayashi, Hiroyuki Wakaguri, Masakazu Shimizu, Koichiro Higasa, Fumihiko Matsuda, Tasuku Honjo
Ago2 and a miRNA reduce Topoisomerase 1 for enhancing DNA cleavage in antibody diversification by activation-induced cytidine deaminase. Proceedings of the National Academy of Sciences of the United States of America 120 (18) (2023)
Maki Kobayashi, Hiroyuki Wakaguri, Masakazu Shimizu, Koichiro Higasa, Fumihiko Matsuda, Tasuku Honjo
Ago2 and a miRNA reduce Topoisomerase 1 for enhancing DNA cleavage in antibody diversification by activation-induced cytidine deaminase. Proceedings of the National Academy of Sciences of the United States of America 120 (18) (2023)
Maki Kobayashi, Hiroyuki Wakaguri, Masakazu Shimizu, Koichiro Higasa, Fumihiko Matsuda, Tasuku Honjo
Ago2 and a miRNA reduce Topoisomerase 1 for enhancing DNA cleavage in antibody diversification by activation-induced cytidine deaminase. Proceedings of the National Academy of Sciences of the United States of America 120 (18) (2023)
Kentaro Tanaka, Kenji Chamoto, Sho Saeki, Ryusuke Hatae, Yuki Ikematsu, Kazuko Sakai, Nobuhisa Ando, Kazuhiro Sonomura, Shinsuke Kojima, Masanori Taketsuna, Young Hak Kim, Hironori Yoshida, Hiroaki Ozasa, Yuichi Sakamori, Tomoko Hirano, Fumihiko Matsuda, Toyohiro Hirai, Kazuto Nishio, Takuro Sakagami, Masanori Fukushima, Yoichi Nakanishi, Tasuku Honjo, Isamu Okamoto
Combination bezafibrate and nivolumab treatment of patients with advanced non-small cell lung cancer. Science translational medicine 14 (675) (2022)
Shingo Matsushima, Masatoshi Hagiwara, Kei Iida, Kenji Chamoto, Tasuku Honjo, Masatoshi Hagiwara
Chemical induction of splice-neoantigens attenuates tumor growth in a preclinical model of colorectal cancer. Science translational medicine 14 (673) (2022)
Muna Al-Habsi, Kenji Chamoto, Ken Matsumoto, Norimichi Nomura, Baihao Zhang, Yuki Sugiura, Kazuhiro Sonomura, Aprilia Maharani, Yuka Nakajima, Yibo Wu, Yayoi Nomura, Rosemary Menzies, Masaki Tajima, Koji Kitaoka, Yasuharu Haku, Sara Delghandi, Keiko Yurimoto, Fumihiko Matsuda, So Iwata, Toshihiko Ogura, Sidonia Fagarasan, Tasuku Honjo
Spermidine activates mitochondrial trifunctional protein and improves antitumor immunity in mice. Science (New York, N.Y.) 378 (6618) (2022)
Farazul Haque, Tasuku Honjo, Nasim A Begum
XLID syndrome gene Med12 promotes Ig isotype switching through chromatin modification and enhancer RNA regulation. Science advances 8 (47) (2022)
Kentaro Tanaka, Kenji Chamoto, Sho Saeki, Ryusuke Hatae, Yuki Ikematsu, Kazuko Sakai, Nobuhisa Ando, Kazuhiro Sonomura, Shinsuke Kojima, Masanori Taketsuna, Young Hak Kim, Hironori Yoshida, Hiroaki Ozasa, Yuichi Sakamori, Tomoko Hirano, Fumihiko Matsuda, Toyohiro Hirai, Kazuto Nishio, Takuro Sakagami, Masanori Fukushima, Yoichi Nakanishi, Tasuku Honjo, Isamu Okamoto
Combination bezafibrate and nivolumab treatment of patients with advanced non-small cell lung cancer. Science translational medicine 14 (675) (2022)
Kentaro Tanaka, Kenji Chamoto, Sho Saeki, Ryusuke Hatae, Yuki Ikematsu, Kazuko Sakai, Nobuhisa Ando, Kazuhiro Sonomura, Shinsuke Kojima, Masanori Taketsuna, Young Hak Kim, Hironori Yoshida, Hiroaki Ozasa, Yuichi Sakamori, Tomoko Hirano, Fumihiko Matsuda, Toyohiro Hirai, Kazuto Nishio, Takuro Sakagami, Masanori Fukushima, Yoichi Nakanishi, Tasuku Honjo, Isamu Okamoto
Combination bezafibrate and nivolumab treatment of patients with advanced non-small cell lung cancer. Science translational medicine 14 (675) (2022)
Nasim A Begum, Farazul Haque, Andre Stanlie, Afzal Husain, Samiran Mondal, Mikiyo Nakata, Takako Taniguchi, Hisaaki Taniguchi, Tasuku Honjo
Phf5a regulates DNA repair in class switch recombination via p400 and histone H2A variant deposition. The EMBO journal 40 (12) (2021)
Masato Ogishi, Rui Yang, Caner Aytekin, David Langlais, Mathieu Bourgey, Taushif Khan, Fatima Al Ali, Mahbuba Rahman, Ottavia M Delmonte, Maya Chrabieh, Peng Zhang, Conor Gruber, Simon J Pelham, András N Spaan, Jérémie Rosain, Wei-Te Lei, Scott Drutman, Matthew D Hellmann, Margaret K Callahan, Matthew J Adamow, Phillip Wong, Jedd D Wolchok, Geetha Rao, Cindy S Ma, Yuka Nakajima, Tomonori Yaguchi, Kenji Chamoto, Samuel C Williams, Jean François Emile, Flore Rozenberg, Michael S Glickman, Franck Rapaport, Gaspard Kerner, Garrett Allington, Ilhan Tezcan, Deniz Çağdaş Ayvaz, Ferda O Hosnut, Figen Dogu, Aydan Ikinciogullari, V Koneti Rao, Leena Kainulainen, Vivien Béziat, Jacinta Bustamante, Silvia Vilarinho, Richard P Lifton, Bertrand Boisson, Laurent Abel, Dusan Bogunovic, Nico Marr, Luigi Daniele Notarangelo, Stuart G Tangye, Tasuku Honjo, Philippe Gros, Stéphanie Boisson-Dupuis, Jean Laurent Casanova
Inherited PD-1 deficiency underlies tuberculosis and autoimmunity in a child. Nature medicine 27 (9) (2021)
Yuka Nakajima, Kenji Chamoto, Takuma Oura, Tasuku Honjo
Critical role of the CD44lowCD62Llow CD8+ T cell subset in restoring antitumor immunity in aged mice. Proceedings of the National Academy of Sciences of the United States of America 118 (23) (2021)
Ziwei Yin, Maki Kobayashi, Wenjun Hu, Koichi Higashi, Nasim A Begum, Ken Kurokawa, Tasuku Honjo
RNA-binding motifs of hnRNP K are critical for induction of antibody diversification by activation-induced cytidine deaminase. Proceedings of the National Academy of Sciences of the United States of America 117 (21) (2020)
Maryam Akrami, Rosemary Menzies, Kenji Chamoto, Michio Miyajima, Ryuji Suzuki, Hiroyuki Sato, Akiko Nishii, Michio Tomura, Sidonia Fagarasan, Tasuku Honjo
Circulation of gut-preactivated naïve CD8+ T cells enhances antitumor immunity in B cell-defective mice. Proceedings of the National Academy of Sciences of the United States of America 117 (38) (2020)
Afzal Husain, Jianliang Xu, Hodaka Fujii, Mikiyo Nakata, Maki Kobayashi, Ji-Yang Wang, Jan Rehwinkel, Tasuku Honjo, Nasim A Begum
SAMHD1-mediated dNTP degradation is required for efficient DNA repair during antibody class switch recombination. The EMBO journal 39 (15) (2020)
Alok Kumar, Kenji Chamoto, Partha S Chowdhury, Tasuku Honjo
Tumors attenuating the mitochondrial activity in T cells escape from PD-1 blockade therapy. eLife 9 (2020)
P S Chowdhury, K Chamoto, Tasuku Honjo
Combination therapy strategies for improving PD-1 blockade efficacy: a new era in cancer immunotherapy. Journal of internal medicine 283 (2) (2017)