So Iwata

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 37

Top Topics

Electron Transfer

Structural Basis

Vascular Smooth Muscle Cells

Top Venues

Nature structural & molecular biology

Nature communications

Nature chemistry

This page only lists publications with an associated author ORCID identifier.

Publications

Hongjie Li, Yoshiki Nakajima, Eriko Nango, Shigeki Owada, Daichi Yamada, Kana Hashimoto, Fangjia Luo, Rie Tanaka, Fusamichi Akita, Koji Kato, Jungmin Kang, Yasunori Saitoh, Shunpei Kishi, Huaxin Yu, Naoki Matsubara, Hajime Fujii, Michihiro Sugahara, Mamoru Suzuki, Tetsuya Masuda, Tetsunari Kimura, Tran Nguyen Thao, Shinichiro Yonekura, Long-Jiang Yu, Takehiko Tosha, Kensure Tono, Yasumasa Joti, Takaki Hatsui, Makina Yabashi, Minoru Kubo, So Iwata, Hiroshi Isobe, Kizashi Yamaguchi, Michihiro Suga, Jian Ren Shen
Oxygen-evolving photosystem II structures during S 1 -S 2 -S 3 transitions. Nature (2024)
Hongjie Li, Yoshiki Nakajima, Eriko Nango, Shigeki Owada, Daichi Yamada, Kana Hashimoto, Fangjia Luo, Rie Tanaka, Fusamichi Akita, Koji Kato, Jungmin Kang, Yasunori Saitoh, Shunpei Kishi, Huaxin Yu, Naoki Matsubara, Hajime Fujii, Michihiro Sugahara, Mamoru Suzuki, Tetsuya Masuda, Tetsunari Kimura, Tran Nguyen Thao, Shinichiro Yonekura, Long-Jiang Yu, Takehiko Tosha, Kensure Tono, Yasumasa Joti, Takaki Hatsui, Makina Yabashi, Minoru Kubo, So Iwata, Hiroshi Isobe, Kizashi Yamaguchi, Michihiro Suga, Jian Ren Shen
Oxygen-evolving photosystem II structures during S 1 -S 2 -S 3 transitions. Nature 626 (7999) (2024)
Hongjie Li, Yoshiki Nakajima, Eriko Nango, Shigeki Owada, Daichi Yamada, Kana Hashimoto, Fangjia Luo, Rie Tanaka, Fusamichi Akita, Koji Kato, Jungmin Kang, Yasunori Saitoh, Shunpei Kishi, Huaxin Yu, Naoki Matsubara, Hajime Fujii, Michihiro Sugahara, Mamoru Suzuki, Tetsuya Masuda, Tetsunari Kimura, Tran Nguyen Thao, Shinichiro Yonekura, Long-Jiang Yu, Takehiko Tosha, Kensure Tono, Yasumasa Joti, Takaki Hatsui, Makina Yabashi, Minoru Kubo, So Iwata, Hiroshi Isobe, Kizashi Yamaguchi, Michihiro Suga, Jian Ren Shen
Oxygen-evolving photosystem II structures during S 1 -S 2 -S 3 transitions. Nature 626 (7999) (2024)
Hongjie Li, Yoshiki Nakajima, Eriko Nango, Shigeki Owada, Daichi Yamada, Kana Hashimoto, Fangjia Luo, Rie Tanaka, Fusamichi Akita, Koji Kato, Jungmin Kang, Yasunori Saitoh, Shunpei Kishi, Huaxin Yu, Naoki Matsubara, Hajime Fujii, Michihiro Sugahara, Mamoru Suzuki, Tetsuya Masuda, Tetsunari Kimura, Tran Nguyen Thao, Shinichiro Yonekura, Long-Jiang Yu, Takehiko Tosha, Kensure Tono, Yasumasa Joti, Takaki Hatsui, Makina Yabashi, Minoru Kubo, So Iwata, Hiroshi Isobe, Kizashi Yamaguchi, Michihiro Suga, Jian Ren Shen
Oxygen-evolving photosystem II structures during S 1 -S 2 -S 3 transitions. Nature (2024)
Hongjie Li, Yoshiki Nakajima, Eriko Nango, Shigeki Owada, Daichi Yamada, Kana Hashimoto, Fangjia Luo, Rie Tanaka, Fusamichi Akita, Koji Kato, Jungmin Kang, Yasunori Saitoh, Shunpei Kishi, Huaxin Yu, Naoki Matsubara, Hajime Fujii, Michihiro Sugahara, Mamoru Suzuki, Tetsuya Masuda, Tetsunari Kimura, Tran Nguyen Thao, Shinichiro Yonekura, Long-Jiang Yu, Takehiko Tosha, Kensure Tono, Yasumasa Joti, Takaki Hatsui, Makina Yabashi, Minoru Kubo, So Iwata, Hiroshi Isobe, Kizashi Yamaguchi, Michihiro Suga, Jian Ren Shen
Oxygen-evolving photosystem II structures during S 1 -S 2 -S 3 transitions. Nature 626 (7999) (2024)
Hongjie Li, Yoshiki Nakajima, Eriko Nango, Shigeki Owada, Daichi Yamada, Kana Hashimoto, Fangjia Luo, Rie Tanaka, Fusamichi Akita, Koji Kato, Jungmin Kang, Yasunori Saitoh, Shunpei Kishi, Huaxin Yu, Naoki Matsubara, Hajime Fujii, Michihiro Sugahara, Mamoru Suzuki, Tetsuya Masuda, Tetsunari Kimura, Tran Nguyen Thao, Shinichiro Yonekura, Long-Jiang Yu, Takehiko Tosha, Kensure Tono, Yasumasa Joti, Takaki Hatsui, Makina Yabashi, Minoru Kubo, So Iwata, Hiroshi Isobe, Kizashi Yamaguchi, Michihiro Suga, Jian Ren Shen
Oxygen-evolving photosystem II structures during S 1 -S 2 -S 3 transitions. Nature 626 (7999) (2024)
Dohyun Im, Jun-Ichi Kishikawa, Yuki Shiimura, Hiromi Hisano, Akane Ito, Yoko Fujita-Fujiharu, Yukihiko Sugita, Takeshi Noda, Takayuki Kato, Hidetsugu Asada, So Iwata
Structural insights into the agonists binding and receptor selectivity of human histamine H 4 receptor. Nature communications 14 (1) (2023)
James Birch, Tristan O C Kwan, Peter J Judge, Danny N Axford, Pierre Aller, Agata Butryn, Rosana I Dos Reis, Juan Francisco Bada Juarez, Javier Vinals, Robin L Owen, Eriko Nango, Rie Tanaka, Kensure Tono, Yasumasa Joti, Tomoyuki Tanaka, Shigeki Owada, Michihiro Sugahara, So Iwata, Allen M Orville, Anthony Watts, Isabel Moraes
A versatile approach to high-density microcrystals in lipidic cubic phase for room-temperature serial crystallography. Journal of applied crystallography 56 (Pt 5) (2023)
Rei Matsuoka, Roman Fudim, Sukkyeong Jung, Chenou Zhang, Andre Bazzone, Yurie Chatzikyriakidou, Carol V Robinson, Norimichi Nomura, So Iwata, Michael Landreh, Laura Orellana, Oliver Beckstein, David Drew
Author Correction: Structure, mechanism and lipid-mediated remodeling of the mammalian Na + /H + exchanger NHA2. Nature structural & molecular biology (2023)
Alexander M Wolff, Eriko Nango, Iris D Young, Aaron S Brewster, Minoru Kubo, Takashi Nomura, Michihiro Sugahara, Shigeki Owada, Benjamin A Barad, Kazutaka Ito, Asmit Bhowmick, Sergio Carbajo, Tomoya Hino, James M Holton, Dohyun Im, Lee J O'Riordan, Tomoyuki Tanaka, Rie Tanaka, Raymond G Sierra, Fumiaki Yumoto, Kensure Tono, So Iwata, Nicholas K Sauter, Brian K Shoichet, Michael C Thompson
Mapping protein dynamics at high spatial resolution with temperature-jump X-ray crystallography. Nature chemistry (2023)
Han Ba Bui, Satoshi Watanabe, Norimichi Nomura, Kehong Liu, Tomoko Uemura, Michio Inoue, Akihisa Tsutsumi, Hiroyuki Fujita, Kengo Kinoshita, Yukinari Kato, So Iwata, Masahide Kikkawa, Kenji Inaba
Cryo-EM structures of human zinc transporter ZnT7 reveal the mechanism of Zn 2+ uptake into the Golgi apparatus. Nature communications 14 (1) (2023)
Cecilia Safari, Swagatha Ghosh, Rebecka Andersson, Jonatan Johannesson, Petra Båth, Owens Uwangue, Peter Dahl, Doris Zorić, Emil Sandelin, Adams Vallejos, Eriko Nango, Rie Tanaka, Robert Bosman, Per Börjesson, Elin Dunevall, Greger Hammarin, Giorgia Ortolani, Matthijs R Panman, Tomoyuki Tanaka, Ayumi Yamashita, Toshi Arima, Michihiro Sugahara, Mamoru Suzuki, Tetsuya Masuda, Hanae Takeda, Raika Yamagiwa, Kazumasa Oda, Masahiro Fukuda, Takehiko Tosha, Hisashi Naitow, Shigeki Owada, Kensure Tono, Osamu Nureki, So Iwata, Richard Neutze, Gisela Brändén
Time-resolved serial crystallography to track the dynamics of carbon monoxide in the active site of cytochrome c oxidase. Science advances 9 (49) (2023)
Kunio Nakata, Tatsuki Kashiwagi, Naoki Kunishima, Hisashi Naitow, Yoshinori Matsuura, Hiroshi Miyano, Toshimi Mizukoshi, Kensure Tono, Makina Yabashi, Eriko Nango, So Iwata
Ambient temperature structure of phosphoketolase from Bifidobacterium longum determined by serial femtosecond X-ray crystallography. Acta crystallographica. Section D, Structural biology (2023)
Manuel Maestre-Reyna, Po-Hsun Wang, Eriko Nango, Yuhei Hosokawa, Martin Saft, Antonia Furrer, Cheng-Han Yang, Eka-Putra Gusti-Ngurah-Putu, Wen-Jin Wu, Hans-Joachim Emmerich, Nicolas Caramello, Sophie Franz-Badur, Chao Yang, Sylvain Engilberge, Maximilian Wranik, Hannah Louise Glover, Tobias Weinert, Hsiang-Yi Wu, Cheng-Chung Lee, Wei-Cheng Huang, Kai-Fa Huang, Yao-Kai Chang, Jiahn-Haur Liao, Jui-Hung Weng, Wael Gad, Chiung-Wen Chang, Allan H Pang, Kai-Chun Yang, Wei-Ting Lin, Yu-Chen Chang, Dardan Gashi, Emma V Beale, Dmitry Ozerov, Karol Nass, Gregor Knopp, Philip J M Johnson, Claudio Cirelli, Christopher J Milne, Camila Bacellar, Michihiro Sugahara, Shigeki Owada, Yasumasa Joti, Ayumi Yamashita, Rie Tanaka, Tomoyuki Tanaka, Fangjia Luo, Kensure Tono, Wiktoria Zarzycka, Pavel Müller, Maisa Alkheder Alahmad, Filipp Bezold, Valerie Fuchs, Petra Gnau, Stephan Kiontke, Lukas Korf, Viktoria Reithofer, Christian Joshua Rosner, Elisa Marie Seiler, Mohamed Watad, Laura Werel, Roberta Spadaccini, Junpei Yamamoto, So Iwata, Dongping Zhong, Joerg Standfuss, Antoine Royant, Yoshitaka Bessho, Lars-Oliver Essen, Ming-Daw Tsai
Visualizing the DNA repair process by a photolyase at atomic resolution. Science (New York, N.Y.) 382 (6674) (2023)
Christopher D M Hutchison, James M Baxter, Ann Fitzpatrick, Gabriel Dorlhiac, Alisia Fadini, Samuel Perrett, Karim Maghlaoui, Salomé Bodet Lefèvre, Violeta Cordon-Preciado, Josie L Ferreira, Volha U Chukhutsina, Douglas Garratt, Jonathan Barnard, Gediminas Galinis, Flo Glencross, Rhodri Marc Morgan, Sian Stockton, Ben Taylor, Letong Yuan, Matthew G Romei, Chi-Yun Lin, Jonathan P Marangos, Marius Schmidt, Viktoria Chatrchyan, Tiago Buckup, Dmitry Morozov, JaeHyun Park, Sehan Park, Intae Eom, Minseok Kim, Dogeun Jang, Hyeongi Choi, HyoJung Hyun, Gisu Park, Eriko Nango, Rie Tanaka, Shigeki Owada, Kensure Tono, Daniel P DePonte, Sergio Carbajo, Matthew H Seaberg, Andrew L Aquila, Sébastien Boutet, Anton Barty, So Iwata, Steven G Boxer, Gerrit Groenhof, Jasper J van Thor
Optical control of ultrafast structural dynamics in a fluorescent protein. Nature chemistry (2023)
Rei Matsuoka, Roman Fudim, Sukkyeong Jung, Chenou Zhang, Andre Bazzone, Yurie Chatzikyriakidou, Carol V Robinson, Norimichi Nomura, So Iwata, Michael Landreh, Laura Orellana, Oliver Beckstein, David Drew
Structure, mechanism and lipid-mediated remodeling of the mammalian Na + /H + exchanger NHA2. Nature structural & molecular biology 29 (2) (2022)
Jae-Hyun Park, Masashi Iwamoto, Ji-Hye Yun, Tomomi Uchikubo-Kamo, Donghwan Son, Zeyu Jin, Hisashi Yoshida, Mio Ohki, Naito Ishimoto, Kenji Mizutani, Mizuki Oshima, Masamichi Muramatsu, Takaji Wakita, Mikako Shirouzu, Kehong Liu, Tomoko Uemura, Norimichi Nomura, So Iwata, Koichi Watashi, Jeremy R H Tame, Tomohiro Nishizawa, Weontae Lee, Sam-Yong Park
Structural insights into the HBV receptor and bile acid transporter NTCP. Nature 606 (7916) (2022)
Manuel Maestre-Reyna, Cheng-Han Yang, Eriko Nango, Wei-Cheng Huang, Eka Putra Gusti Ngurah Putu, Wen-Jin Wu, Po-Hsun Wang, Sophie Franz-Badur, Martin Saft, Hans-Joachim Emmerich, Hsiang-Yi Wu, Cheng-Chung Lee, Kai-Fa Huang, Yao-Kai Chang, Jiahn-Haur Liao, Jui-Hung Weng, Wael Gad, Chiung-Wen Chang, Allan H Pang, Michihiro Sugahara, Shigeki Owada, Yuhei Hosokawa, Yasumasa Joti, Ayumi Yamashita, Rie Tanaka, Tomoyuki Tanaka, Fangjia Luo, Kensure Tono, Kai-Cheng Hsu, Stephan Kiontke, Igor Schapiro, Roberta Spadaccini, Antoine Royant, Junpei Yamamoto, So Iwata, Lars-Oliver Essen, Yoshitaka Bessho, Ming-Daw Tsai
Serial crystallography captures dynamic control of sequential electron and proton transfer events in a flavoenzyme. Nature chemistry 14 (6) (2022)
Muna Al-Habsi, Kenji Chamoto, Ken Matsumoto, Norimichi Nomura, Baihao Zhang, Yuki Sugiura, Kazuhiro Sonomura, Aprilia Maharani, Yuka Nakajima, Yibo Wu, Yayoi Nomura, Rosemary Menzies, Masaki Tajima, Koji Kitaoka, Yasuharu Haku, Sara Delghandi, Keiko Yurimoto, Fumihiko Matsuda, So Iwata, Toshihiko Ogura, Sidonia Fagarasan, Tasuku Honjo
Spermidine activates mitochondrial trifunctional protein and improves antitumor immunity in mice. Science (New York, N.Y.) 378 (6618) (2022)
Xiaohong Liu, Pengcheng Liu, Hongjie Li, Zhen Xu, Lu Jia, Yan Xia, Minling Yu, Wenqin Tang, Xiaolei Zhu, Chao Chen, Yuanlin Zhang, Eriko Nango, Rie Tanaka, Fangjia Luo, Koji Kato, Yoshiki Nakajima, Shunpei Kishi, Huaxin Yu, Naoki Matsubara, Shigeki Owada, Kensure Tono, So Iwata, Long-Jiang Yu, Jian Ren Shen, Jiangyun Wang
Excited-state intermediates in a designer protein encoding a phototrigger caught by an X-ray free-electron laser. Nature chemistry 14 (9) (2022)
Takeshi Murakawa, Mamoru Suzuki, Kenji Fukui, Tetsuya Masuda, Michihiro Sugahara, Kensure Tono, Tomoyuki Tanaka, So Iwata, Eriko Nango, Takato Yano, Katsuyuki Tanizawa, Toshihide Okajima
Serial femtosecond X-ray crystallography of an anaerobically formed catalytic intermediate of copper amine oxidase. Acta crystallographica. Section D, Structural biology 78 (Pt 12) (2022)
Dongqing Pan, Ryo Oyama, Tomomi Sato, Takanori Nakane, Ryo Mizunuma, Keita Matsuoka, Yasumasa Joti, Kensure Tono, Eriko Nango, So Iwata, Toru Nakatsu, Hiroaki Kato
Crystal structure of CmABCB1 multi-drug exporter in lipidic mesophase revealed by LCP-SFX. IUCrJ 9 (Pt 1) (2021)
Shintaro Maeda, Yuki Shiimura, Hidetsugu Asada, Kunio Hirata, Fangjia Luo, Eriko Nango, Nobuo Tanaka, Masayasu Toyomoto, Asuka Inoue, Junken Aoki, So Iwata, Masatoshi Hagiwara
Endogenous agonist-bound S1PR3 structure reveals determinants of G protein-subtype bias. Science advances 7 (24) (2021)
Stephanie L Begg, Jennie Sjöhamn, Jacinta A Watts, Hugo I MacDermott-Opeskin, Stephen J Fairweather, Katherine Ganio, Alex Carey Hulyer, Aaron P McGrath, Andrew J Hayes, Tess R Malcolm, Mark R Davies, Norimichi Nomura, So Iwata, Megan L O'Mara, Megan J Maher, Christopher A McDevitt
The structural basis of bacterial manganese import. Science advances 7 (32) (2021)
Dmitry Ghilarov, Satomi Inaba-Inoue, Piotr Stepien, Feng Qu, Elizabeth Michalczyk, Zuzanna Pakosz, Norimichi Nomura, Satoshi Ogasawara, Graham Charles Walker, Sylvie Rebuffat, So Iwata, Jonathan Gardiner Heddle, Konstantinos Beis
Molecular mechanism of SbmA, a promiscuous transporter exploited by antimicrobial peptides. Science advances 7 (37) (2021)
Yuki Shiimura, Shoichiro Horita, Akie Hamamoto, Hidetsugu Asada, Kunio Hirata, Misuzu Tanaka, Kenji Mori, Tomoko Uemura, Takuya Kobayashi, So Iwata, Masayasu Kojima
Structure of an antagonist-bound ghrelin receptor reveals possible ghrelin recognition mode. Nature communications 11 (1) (2020)
Kazuaki Matoba, Tetsuya Kotani, Akihisa Tsutsumi, Takuma Tsuji, Takaharu Mori, Daisuke Noshiro, Yuji Sugita, Norimichi Nomura, So Iwata, Yoshinori Ohsumi, Toyoshi Fujimoto, Hitoshi Nakatogawa, Masahide Kikkawa, Nobuo N Noda
Atg9 is a lipid scramblase that mediates autophagosomal membrane expansion. Nature structural & molecular biology 27 (12) (2020)
Dohyun Im, Asuka Inoue, Takaaki Fujiwara, Takanori Nakane, Yasuaki Yamanaka, Tomoko Uemura, Chihiro Mori, Yuki Shiimura, Kanako Terakado Kimura, Hidetsugu Asada, Norimichi Nomura, Tomoyuki Tanaka, Ayumi Yamashita, Eriko Nango, Kensuke Tono, Francois Marie Ngako Kadji, Junken Aoki, So Iwata, Tatsuro Shimamura
Structure of the dopamine D2 receptor in complex with the antipsychotic drug spiperone. Nature communications 11 (1) (2020)
Rie Umeda, Yuhkoh Satouh, Mizuki Takemoto, Yoshiko Nakada-Nakura, Kehong Liu, Takeshi Yokoyama, Mikako Shirouzu, So Iwata, Norimichi Nomura, Ken Sato, Masahito Ikawa, Tomohiro Nishizawa, Osamu Nureki
Structural insights into tetraspanin CD9 function. Nature communications 11 (1) (2020)
Hikaru Miyagi, Hidetsugu Asada, Michihiko Suzuki, Yuichi Takahashi, Mai Yasunaga, Chiyo Suno, So Iwata, Jun-Ichi Saito
The discovery of a new antibody for BRIL-fused GPCR structure determination. Scientific reports 10 (1) (2020)
Tomoaki Kinjo, Kenta Terai, Shoichiro Horita, Norimichi Nomura, Kenta Sumiyama, Kaori Togashi, So Iwata, Michiyuki Matsuda
FRET-assisted photoactivation of flavoproteins for in vivo two-photon optogenetics. Nature methods 16 (10) (2019)
Kanako Terakado Kimura, Hidetsugu Asada, Asuka Inoue, Francois Marie Ngako Kadji, Dohyun Im, Chihiro Mori, Takatoshi Arakawa, Kunio Hirata, Yayoi Nomura, Norimichi Nomura, Junken Aoki, So Iwata, Tatsuro Shimamura
Structures of the 5-HT2A receptor in complex with the antipsychotics risperidone and zotepine. Nature structural & molecular biology 26 (2) (2019)
Przemyslaw Nogly, Tobias Weinert, Daniel James, Sergio Carbajo, Dmitry Ozerov, Antonia Furrer, Dardan Gashi, Veniamin A Borin, Petr Skopintsev, Kathrin Jaeger, Karol Nass, Petra Båth, Robert Bosman, Jason E Koglin, Matthew H Seaberg, Thomas J Lane, Demet Kekilli, Steffen Brünle, Tomoyuki Tanaka, Wenting Wu, Christopher J Milne, Thomas A White, Anton Barty, Uwe Weierstall, Valerie Panneels, Eriko Nango, So Iwata, Mark Hunter, Igor Schapiro, Gebhard F X Schertler, Richard Neutze, Joerg Standfuss
Retinal isomerization in bacteriorhodopsin captured by a femtosecond x-ray laser. Science (New York, N.Y.) 361 (6398) (2018)
Kazushi Morimoto, Ryoji Suno, Yunhong Hotta, Keitaro Yamashita, Kunio Hirata, Masaki Yamamoto, Shuh Narumiya, So Iwata, Takuya Kobayashi
Crystal structure of the endogenous agonist-bound prostanoid receptor EP3. Nature chemical biology 15 (1) (2018)
Hidetsugu Asada, Shoichiro Horita, Kunio Hirata, Mitsunori Shiroishi, Yuki Shiimura, Hiroko Iwanari, Takao Hamakubo, Tatsuro Shimamura, Norimichi Nomura, Osamu Kusano-Arai, Tomoko Uemura, Chiyo Suno, Takuya Kobayashi, So Iwata
Crystal structure of the human angiotensin II type 2 receptor bound to an angiotensin II analog. Nature structural & molecular biology 25 (7) (2018)
Ryoji Suno, Sangbae Lee, Shoji Maeda, Satoshi Yasuda, Keitaro Yamashita, Kunio Hirata, Shoichiro Horita, Maki S Tawaramoto, Hirokazu Tsujimoto, Takeshi Murata, Masahiro Kinoshita, Masaki Yamamoto, Brian K Kobilka, Nagarajan Vaidehi, So Iwata, Takuya Kobayashi
Structural insights into the subtype-selective antagonist binding to the M2 muscarinic receptor. Nature chemical biology 14 (12) (2018)
Yosuke Toyoda, Kazushi Morimoto, Ryoji Suno, Shoichiro Horita, Keitaro Yamashita, Kunio Hirata, Yusuke Sekiguchi, Satoshi Yasuda, Mitsunori Shiroishi, Tomoko Shimizu, Yuji Urushibata, Yuta Kajiwara, Tomoaki Inazumi, Yunhong Hotta, Hidetsugu Asada, Takanori Nakane, Yuki Shiimura, Tomoya Nakagita, Kyoshiro Tsuge, Suguru Yoshida, Tomoko Kuribara, Takamitsu Hosoya, Yukihiko Sugimoto, Norimichi Nomura, Miwa Sato, Takatsugu Hirokawa, Masahiro Kinoshita, Takeshi Murata, Kiyoshi Takayama, Masaki Yamamoto, Shuh Narumiya, So Iwata, Takuya Kobayashi
Ligand binding to human prostaglandin E receptor EP4 at the lipid-bilayer interface. Nature chemical biology 15 (1) (2018)