Timothy J C Tan

Publication Activity (10 Years)

Years Active: 2021-2024
Publications (10 Years): 28

Top Topics

Arabidopsis Thaliana

Top Venues

Nature communications

bioRxiv : the preprint server for biology

Proceedings of the National Academy of Sciences of the United States of America

Science advances

This page only lists publications with an associated author ORCID identifier.

Publications

Ruipeng Lei, Enya Qing, Abby Odle, Meng Yuan, Chaminda D Gunawardene, Timothy J C Tan, Natalie So, Wenhao O Ouyang, Ian A Wilson, Thomas Gallagher, Stanley Perlman, Nicholas C Wu, Lok-Yin Roy Wong
Functional and antigenic characterization of SARS-CoV-2 spike fusion peptide by deep mutational scanning. Nature communications 15 (1) (2024)
Timothy J C Tan, Abhishek K Verma, Abby Odle, Ruipeng Lei, David K Meyerholz, Kenneth A Matreyek, Stanley Perlman, Lok-Yin Roy Wong, Nicholas C Wu
Evidence of antigenic drift in the fusion machinery core of SARS-CoV-2 spike. Proceedings of the National Academy of Sciences of the United States of America 121 (15) (2024)
Timothy J C Tan, Abhishek K Verma, Abby Odle, Ruipeng Lei, David K Meyerholz, Kenneth A Matreyek, Stanley Perlman, Lok-Yin Roy Wong, Nicholas C Wu
Evidence of antigenic drift in the fusion machinery core of SARS-CoV-2 spike. Proceedings of the National Academy of Sciences of the United States of America 121 (15) (2024)
Ruipeng Lei, Nicholas C Wu, Wenhao O Ouyang, Andrea Hernandez Garcia, Chika Kikuchi, Shengyang Wang, Ryan McBride, Timothy J C Tan, Yuanxin Sun, Chunke Chen, Claire S Graham, Lucia A Rodriguez, Ivana R Shen, Danbi Choi, Roberto Bruzzone, James C Paulson, Satish K Nair, Chris Ka Pun Mok, Nicholas C Wu
Epistasis mediates the evolution of the receptor binding mode in recent human H3N2 hemagglutinin. Nature communications 15 (1) (2024)
Timothy J C Tan, Abhishek K Verma, Abby Odle, Ruipeng Lei, David K Meyerholz, Kenneth A Matreyek, Stanley Perlman, Lok-Yin Roy Wong, Nicholas C Wu
Evidence of antigenic drift in the fusion machinery core of SARS-CoV-2 spike. Proceedings of the National Academy of Sciences of the United States of America 121 (15) (2024)
Ruipeng Lei, Enya Qing, Abby Odle, Meng Yuan, Chaminda D Gunawardene, Timothy J C Tan, Natalie So, Wenhao O Ouyang, Ian A Wilson, Thomas Gallagher, Stanley Perlman, Nicholas C Wu, Lok-Yin Roy Wong
Functional and antigenic characterization of SARS-CoV-2 spike fusion peptide by deep mutational scanning. Nature communications 15 (1) (2024)
Ruipeng Lei, Enya Qing, Abby Odle, Meng Yuan, Chaminda D Gunawardene, Timothy J C Tan, Natalie So, Wenhao O Ouyang, Ian A Wilson, Thomas Gallagher, Stanley Perlman, Nicholas C Wu, Lok-Yin Roy Wong
Functional and antigenic characterization of SARS-CoV-2 spike fusion peptide by deep mutational scanning. Nature communications 15 (1) (2024)
Ruipeng Lei, Nicholas C Wu, Wenhao O Ouyang, Andrea Hernandez Garcia, Chika Kikuchi, Shengyang Wang, Ryan McBride, Timothy J C Tan, Yuanxin Sun, Chunke Chen, Claire S Graham, Lucia A Rodriguez, Ivana R Shen, Danbi Choi, Roberto Bruzzone, James C Paulson, Satish K Nair, Chris Ka Pun Mok, Nicholas C Wu
Epistasis mediates the evolution of the receptor binding mode in recent human H3N2 hemagglutinin. Nature communications 15 (1) (2024)
Tongyu Liu, William K Reiser, Timothy J C Tan, Huibin Lv, Joel Rivera-Cardona, Kyle Heimburger, Nicholas C Wu, Christopher B Brooke
Natural variation in neuraminidase activity influences the evolutionary potential of the seasonal H1N1 lineage hemagglutinin. bioRxiv : the preprint server for biology (2024)
Tongyu Liu, William K Reiser, Timothy J C Tan, Huibin Lv, Joel Rivera-Cardona, Kyle Heimburger, Nicholas C Wu, Christopher B Brooke
Natural variation in neuraminidase activity influences the evolutionary potential of the seasonal H1N1 lineage hemagglutinin. bioRxiv : the preprint server for biology (2024)
Timothy J C Tan, Abhishek K Verma, Abby Odle, Ruipeng Lei, David K Meyerholz, Kenneth A Matreyek, Stanley Perlman, Lok-Yin Roy Wong, Nicholas C Wu
Evidence of antigenic drift in the fusion machinery core of SARS-CoV-2 spike. Proceedings of the National Academy of Sciences of the United States of America 121 (15) (2024)
Joel Rivera-Cardona, Neeha Kakuturu, Elizabeth F Rowland, Qi Wen Teo, Elizabeth A Thayer, Timothy J C Tan, Jiayi Sun, Collin Kieffer, Nicholas C Wu, Christopher B Brooke
Seasonal influenza A virus lineages exhibit divergent abilities to antagonize interferon induction and signaling. bioRxiv : the preprint server for biology (2024)
Ruipeng Lei, Enya Qing, Abby Odle, Meng Yuan, Chaminda D Gunawardene, Timothy J C Tan, Natalie So, Wenhao O Ouyang, Ian A Wilson, Thomas Gallagher, Stanley Perlman, Nicholas C Wu, Lok-Yin Roy Wong
Functional and antigenic characterization of SARS-CoV-2 spike fusion peptide by deep mutational scanning. Nature communications 15 (1) (2024)
Ruipeng Lei, Nicholas C Wu, Wenhao O Ouyang, Andrea Hernandez Garcia, Chika Kikuchi, Shengyang Wang, Ryan McBride, Timothy J C Tan, Yuanxin Sun, Chunke Chen, Claire S Graham, Lucia A Rodriguez, Ivana R Shen, Danbi Choi, Roberto Bruzzone, James C Paulson, Satish K Nair, Chris Ka Pun Mok, Nicholas C Wu
Epistasis mediates the evolution of the receptor binding mode in recent human H3N2 hemagglutinin. Nature communications 15 (1) (2024)
Qi Wen Teo, Yiquan Wang, Huibin Lv, Kevin J Mao, Timothy J C Tan, Yang Wei Huan, Joel Rivera-Cardona, Evan K Shao, Danbi Choi, Zahra Tavakoli Dargani, Christopher B Brooke, Nicholas C Wu
Deep mutational scanning of influenza A virus NEP reveals pleiotropic mutations in its N-terminal domain. bioRxiv : the preprint server for biology (2024)
Ruipeng Lei, Nicholas C Wu, Wenhao O Ouyang, Andrea Hernandez Garcia, Chika Kikuchi, Shengyang Wang, Ryan McBride, Timothy J C Tan, Yuanxin Sun, Chunke Chen, Claire S Graham, Lucia A Rodriguez, Ivana R Shen, Danbi Choi, Roberto Bruzzone, James C Paulson, Satish K Nair, Chris Ka Pun Mok, Nicholas C Wu
Epistasis mediates the evolution of the receptor binding mode in recent human H3N2 hemagglutinin. Nature communications 15 (1) (2024)
Meng Yuan, Ziqi Feng, Huibin Lv, Natalie So, Ivana R Shen, Timothy J C Tan, Qi Wen Teo, Wenhao O Ouyang, Logan Talmage, Ian A Wilson, Nicholas C Wu
Widespread impact of immunoglobulin V gene allelic polymorphisms on antibody reactivity. bioRxiv : the preprint server for biology (2023)
Timothy J C Tan, Zongjun Mou, Ruipeng Lei, Wenhao O Ouyang, Meng Yuan, Sophie Ge Song, Raiees Andrabi, Ian A Wilson, Collin Kieffer, Xinghong Dai, Kenneth A Matreyek, Nicholas C Wu
High-throughput identification of prefusion-stabilizing mutations in SARS-CoV-2 spike. Nature communications 14 (1) (2023)
Qi Wen Teo, Yiquan Wang, Huibin Lv, Timothy J C Tan, Ruipeng Lei, Kevin J Mao, Nicholas C Wu
Stringent and complex sequence constraints of an IGHV1-69 broadly neutralizing antibody to influenza HA stem. bioRxiv : the preprint server for biology (2023)
Yiquan Wang, Huibin Lv, Ruipeng Lei, Yuen-Hei Yeung, Ivana R Shen, Danbi Choi, Qi Wen Teo, Timothy J C Tan, Akshita B Gopal, Xin Chen, Claire S Graham, Nicholas C Wu
An explainable language model for antibody specificity prediction using curated influenza hemagglutinin antibodies. bioRxiv : the preprint server for biology (2023)
Ruipeng Lei, Enya Qing, Abby Odle, Meng Yuan, Timothy J C Tan, Natalie So, Wenhao O Ouyang, Ian A Wilson, Tom Gallagher, Stanley Perlman, Nicholas C Wu, Lok-Yin Roy Wong
Functional and antigenic characterization of SARS-CoV-2 spike fusion peptide by deep mutational scanning. bioRxiv : the preprint server for biology (2023)
Wenhao O Ouyang, Timothy J C Tan, Ruipeng Lei, Sophie Ge Song, Collin Kieffer, Raiees Andrabi, Kenneth A Matreyek, Nicholas C Wu
Probing the biophysical constraints of SARS-CoV-2 spike N-terminal domain using deep mutational scanning. Science advances 8 (47) (2022)
Ruipeng Lei, Timothy J C Tan, Andrea Hernandez Garcia, Yiquan Wang, Meghan Diefenbacher, Chuyun Teo, Gopika Gopan, Zahra Tavakoli Dargani, Qi Wen Teo, Claire S Graham, Christopher B Brooke, Satish K Nair, Nicholas C Wu
Prevalence and mechanisms of evolutionary contingency in human influenza H3N2 neuraminidase. Nature communications 13 (1) (2022)
Meghan Diefenbacher, Timothy J C Tan, David L V Bauer, Beth M Stadtmueller, Nicholas C Wu, Christopher B Brooke
Interactions between Influenza A Virus Nucleoprotein and Gene Segment Untranslated Regions Facilitate Selective Modulation of Viral Gene Expression. Journal of virology 96 (10) (2022)
Timothy J C Tan, Zongjun Mou, Ruipeng Lei, Wenhao O Ouyang, Meng Yuan, Ge Song, Raiees Andrabi, Ian A Wilson, Collin Kieffer, Xinghong Dai, Kenneth A Matreyek, Nicholas C Wu
High-throughput identification of prefusion-stabilizing mutations in SARS-CoV-2 spike. bioRxiv : the preprint server for biology (2022)
Hendrik Reuper, Benjamin Götte, Lucy Williams, Timothy J C Tan, Gerald M McInerney, Marc Dominik Panas, Björn Krenz
Arabidopsis thaliana G3BP Ortholog Rescues Mammalian Stress Granule Phenotype across Kingdoms. International journal of molecular sciences 22 (12) (2021)
Timothy J C Tan, Meng Yuan, Kaylee Kuzelka, Gilberto C Padron, Jacob R Beal, Xin Chen, Yiquan Wang, Joel Rivera-Cardona, Xueyong Zhu, Beth M Stadtmueller, Christopher B Brooke, Ian A Wilson, Nicholas C Wu
Sequence signatures of two public antibody clonotypes that bind SARS-CoV-2 receptor binding domain. Nature communications 12 (1) (2021)
Kui K Chan, Timothy J C Tan, Krishna K Narayanan, Erik Procko
An engineered decoy receptor for SARS-CoV-2 broadly binds protein S sequence variants. Science advances 7 (8) (2021)