Kenneth A Matreyek

ORCID

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 28

Top Venues

bioRxiv : the preprint server for biology

PLoS pathogens

Proceedings of the National Academy of Sciences of the United States of America

Science (New York, N.Y.)

Case Western Reserve University

Harvard University (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Case Western Reserve University Sep 01 2019

United States

Assistant Professor :: Pathology

University of Washington

United States

Postdoctoral Fellow :: Genome Sciences

Dana Farber Cancer Institute

United States

Postdoctoral Fellow :: Cancer, Immunology, and AIDS

Education History

Harvard University

United States

PHD :: Virology

University of California Los Angeles

United States

BSC :: Microbiology, Immunology, and Molecular Genetics

Publications

Timothy J C Tan, Abhishek K Verma, Abby Odle, Ruipeng Lei, David K Meyerholz, Kenneth A Matreyek, Stanley Perlman, Lok-Yin Roy Wong, Nicholas C Wu
Evidence of antigenic drift in the fusion machinery core of SARS-CoV-2 spike. Proceedings of the National Academy of Sciences of the United States of America 121 (15) (2024)
Nidhi Shukla, Sarah M Roelle, John C Snell, Olivia DelSignore, Anna M Bruchez, Kenneth A Matreyek
Pseudotyped virus infection of multiplexed ACE2 libraries reveals SARS-CoV-2 variant shifts in receptor usage. PLoS pathogens 20 (5) (2024)
Nidhi Shukla, Sarah M Roelle, John C Snell, Olivia DelSignore, Anna M Bruchez, Kenneth A Matreyek
Pseudotyped virus infection of multiplexed ACE2 libraries reveals SARS-CoV-2 variant shifts in receptor usage. PLoS pathogens 20 (5) (2024)
Nidhi Shukla, Sarah M Roelle, John C Snell, Olivia DelSignore, Anna M Bruchez, Kenneth A Matreyek
Pseudotyped virus infection of multiplexed ACE2 libraries reveals SARS-CoV-2 variant shifts in receptor usage. PLoS pathogens 20 (5) (2024)
Timothy J C Tan, Abhishek K Verma, Abby Odle, Ruipeng Lei, David K Meyerholz, Kenneth A Matreyek, Stanley Perlman, Lok-Yin Roy Wong, Nicholas C Wu
Evidence of antigenic drift in the fusion machinery core of SARS-CoV-2 spike. Proceedings of the National Academy of Sciences of the United States of America 121 (15) (2024)
Nidhi Shukla, Sarah M Roelle, John C Snell, Olivia DelSignore, Anna M Bruchez, Kenneth A Matreyek
Pseudotyped virus infection of multiplexed ACE2 libraries reveals SARS-CoV-2 variant shifts in receptor usage. bioRxiv : the preprint server for biology (2024)
Timothy J C Tan, Abhishek K Verma, Abby Odle, Ruipeng Lei, David K Meyerholz, Kenneth A Matreyek, Stanley Perlman, Lok-Yin Roy Wong, Nicholas C Wu
Evidence of antigenic drift in the fusion machinery core of SARS-CoV-2 spike. Proceedings of the National Academy of Sciences of the United States of America 121 (15) (2024)
Nidhi Shukla, Sarah M Roelle, John C Snell, Olivia DelSignore, Anna M Bruchez, Kenneth A Matreyek
Pseudotyped virus infection of multiplexed ACE2 libraries reveals SARS-CoV-2 variant shifts in receptor usage. bioRxiv : the preprint server for biology (2024)
Timothy J C Tan, Abhishek K Verma, Abby Odle, Ruipeng Lei, David K Meyerholz, Kenneth A Matreyek, Stanley Perlman, Lok-Yin Roy Wong, Nicholas C Wu
Evidence of antigenic drift in the fusion machinery core of SARS-CoV-2 spike. Proceedings of the National Academy of Sciences of the United States of America 121 (15) (2024)
Nidhi Shukla, Sarah M Roelle, John C Snell, Olivia DelSignore, Anna M Bruchez, Kenneth A Matreyek
Pseudotyped virus infection of multiplexed ACE2 libraries reveals SARS-CoV-2 variant shifts in receptor usage. bioRxiv : the preprint server for biology (2024)
Nidhi Shukla, Sarah M Roelle, John C Snell, Olivia DelSignore, Anna M Bruchez, Kenneth A Matreyek
Pseudotyped virus infection of multiplexed ACE2 libraries reveals SARS-CoV-2 variant shifts in receptor usage. PLoS pathogens 20 (5) (2024)
Nidhi Shukla, Sarah M Roelle, John C Snell, Olivia DelSignore, Anna M Bruchez, Kenneth A Matreyek
Pseudotyped virus infection of multiplexed ACE2 libraries reveals SARS-CoV-2 variant shifts in receptor usage. PLoS pathogens 20 (5) (2024)
Nidhi Shukla, Sarah M Roelle, John C Snell, Olivia DelSignore, Anna M Bruchez, Kenneth A Matreyek
Pseudotyped virus infection of multiplexed ACE2 libraries reveals SARS-CoV-2 variant shifts in receptor usage. bioRxiv : the preprint server for biology (2024)
Sarah M Roelle, Nisha D Kamath, Kenneth A Matreyek
Mammalian Genomic Manipulation with Orthogonal Bxb1 DNA Recombinase Sites for the Functional Characterization of Protein Variants. ACS synthetic biology (2023)
Ayesha Muhammad, Maria E Calandranis, Bian Li, Tao Yang, Daniel J Blackwell, M Lorena Harvey, Jeremy E Smith, Ashli E Chew, Anthony Capra, Kenneth A Matreyek, Douglas M Fowler, Dan M Roden, Andrew M Glazer
High-throughput functional mapping of variants in an arrhythmia gene, KCNE1 , reveals novel biology. bioRxiv : the preprint server for biology (2023)
Ayesha Muhammad, Maria E Calandranis, Bian Li, Tao Yang, Daniel J Blackwell, M Lorena Harvey, Jeremy E Smith, Ashli E Chew, Anthony Capra, Kenneth A Matreyek, Douglas M Fowler, Dan M Roden, Andrew M Glazer
High-throughput functional mapping of variants in an arrhythmia gene, KCNE1 , reveals novel biology. bioRxiv : the preprint server for biology (2023)
Timothy J C Tan, Zongjun Mou, Ruipeng Lei, Wenhao O Ouyang, Meng Yuan, Sophie Ge Song, Raiees Andrabi, Ian A Wilson, Collin Kieffer, Xinghong Dai, Kenneth A Matreyek, Nicholas C Wu
High-throughput identification of prefusion-stabilizing mutations in SARS-CoV-2 spike. Nature communications 14 (1) (2023)
Michael Rappleye, Sarah J Wait, Justin Daho Lee, Jamison C Siebart, Lily Torp, Netta Smith, Jeanot Muster, Kenneth A Matreyek, Douglas M Fowler, Andre Berndt
Optogenetic Microwell Array Screening System: A High-Throughput Engineering Platform for Genetically Encoded Fluorescent Indicators. ACS sensors (2023)
Ayesha Muhammad, Maria E Calandranis, Bian Li, Tao Yang, Daniel J Blackwell, M Lorena Harvey, Jeremy E Smith, Ashli E Chew, Anthony Capra, Kenneth A Matreyek, Douglas M Fowler, Dan M Roden, Andrew M Glazer
High-throughput functional mapping of variants in an arrhythmia gene, KCNE1 , reveals novel biology. bioRxiv : the preprint server for biology (2023)
Ariana Ghez Farrell, Bernadeta Dadonaite, Allison J Greaney, Rachel Eguia, Andrea N Loes, Nicholas M Franko, Jennifer K Logue, Juan Manuel Carreño, Anass Abbad, Helen Y Chu, Kenneth A Matreyek, Jesse D Bloom
Receptor-Binding Domain (RBD) Antibodies Contribute More to SARS-CoV-2 Neutralization When Target Cells Express High Levels of ACE2. Viruses 14 (9) (2022)
Wenhao O Ouyang, Timothy J C Tan, Ruipeng Lei, Sophie Ge Song, Collin Kieffer, Raiees Andrabi, Kenneth A Matreyek, Nicholas C Wu
Probing the biophysical constraints of SARS-CoV-2 spike N-terminal domain using deep mutational scanning. Science advances 8 (47) (2022)
Tyler N Starr, Allison J Greaney, William W Hannon, Andrea N Loes, Kevin Hauser, Josh R Dillen, Elena Ferri, Ariana Ghez Farrell, Bernadeta Dadonaite, Matthew McCallum, Kenneth A Matreyek, Davide Corti, David J Veesler, Gyorgy Snell, Jesse D Bloom
Shifting mutational constraints in the SARS-CoV-2 receptor-binding domain during viral evolution. Science (New York, N.Y.) 377 (6604) (2022)
Sarah M Roelle, Nidhi Shukla, Anh T Pham, Anna M Bruchez, Kenneth A Matreyek
Expanded ACE2 dependencies of diverse SARS-like coronavirus receptor binding domains. PLoS biology 20 (7) (2022)
Kenneth A Matreyek, Jason J Stephany, Ethan Ahler, Douglas M Fowler
Integrating thousands of PTEN variant activity and abundance measurements reveals variant subgroups and new dominant negatives in cancers. Genome medicine 13 (1) (2021)
Nidhi Shukla, Sarah M Roelle, Vinicius G Suzart, Anna M Bruchez, Kenneth A Matreyek
Mutants of human ACE2 differentially promote SARS-CoV and SARS-CoV-2 spike mediated infection. PLoS pathogens 17 (7) (2021)
Jesse T Chao, Rocio Hollman, Warren M Meyers, Fabian Meili, Kenneth A Matreyek, Pamela Dean, Douglas M Fowler, Kurt Haas, Calvin D Roskelley, Christopher J R Loewen
A Premalignant Cell-Based Model for Functionalization and Classification of PTEN Variants. Cancer research 80 (13) (2020)
Anna M Bruchez, Ky Sha, Joshua C Johnson, Li Chen, Caroline Stefani, Hannah McConnell, Lea Gaucherand, Rachel Prins, Kenneth A Matreyek, Adam J Hume, Elke Mühlberger, Emmett V Schmidt, Gene G Olinger, Lynda M Stuart, Adam Lacy-Hulbert
MHC class II transactivator CIITA induces cell resistance to Ebola virus and SARS-like coronaviruses. Science (New York, N.Y.) 370 (6513) (2020)
Kenneth A Matreyek, Lea M Starita, Jason J Stephany, Beth K Martin, Melissa A Chiasson, Vanessa E Gray, Martin Kircher, Arineh Khechaduri, Jennifer N Dines, Ronald J Hause, Smita Bhatia, Williams E Evans, Mary V Relling, Wenjian Yang, Jay Shendure, Douglas M Fowler
Multiplex assessment of protein variant abundance by massively parallel sequencing. Nature genetics 50 (6) (2018)

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Publication Activity (10 Years)

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Kenneth A Matreyek