Tommi P Kilpeläinen (Tommi Kilpeläinen)

Publication Activity (10 Years)

Years Active: 2021-2024
Publications (10 Years): 6

Top Topics

Molecular Dynamics Simulations

Protein Protein

Men Who Have Sex With Men

Top Venues

Journal of medicinal chemistry

Science translational medicine

ACS medicinal chemistry letters

This page only lists publications with an associated author ORCID identifier.

Publications

Henri T Pätsi, Tommi P Kilpeläinen, Mikael Jumppanen, Johanna K Uhari-Väänänen, Pieter Van Wielendaele, Francesca De Lorenzo, Hengjing Cui, Samuli Auno, Janne Saharinen, Erin Seppälä, Nina H Sipari, Juha R Savinainen, Ingrid De Meester, Anne-Marie Lambeir, Maija K Lahtela-Kakkonen, Timo T Myöhänen, Erik A A Wallén
5-Aminothiazoles Reveal a New Ligand-Binding Site on Prolyl Oligopeptidase Which is Important for Modulation of Its Protein-Protein Interaction-Derived Functions. Journal of medicinal chemistry 67 (7) (2024)
Henri T Pätsi, Tommi P Kilpeläinen, Mikael Jumppanen, Johanna K Uhari-Väänänen, Pieter Van Wielendaele, Francesca De Lorenzo, Hengjing Cui, Samuli Auno, Janne Saharinen, Erin Seppälä, Nina H Sipari, Juha R Savinainen, Ingrid De Meester, Anne-Marie Lambeir, Maija K Lahtela-Kakkonen, Timo T Myöhänen, Erik A A Wallén
5-Aminothiazoles Reveal a New Ligand-Binding Site on Prolyl Oligopeptidase Which is Important for Modulation of Its Protein-Protein Interaction-Derived Functions. Journal of medicinal chemistry 67 (7) (2024)
Henri T Pätsi, Tommi P Kilpeläinen, Mikael Jumppanen, Johanna K Uhari-Väänänen, Pieter Van Wielendaele, Francesca De Lorenzo, Hengjing Cui, Samuli Auno, Janne Saharinen, Erin Seppälä, Nina H Sipari, Juha R Savinainen, Ingrid De Meester, Anne-Marie Lambeir, Maija K Lahtela-Kakkonen, Timo T Myöhänen, Erik A A Wallén
5-Aminothiazoles Reveal a New Ligand-Binding Site on Prolyl Oligopeptidase Which is Important for Modulation of Its Protein-Protein Interaction-Derived Functions. Journal of medicinal chemistry (2024)
Tony S Eteläinen, M Catarina Silva, Johanna K Uhari-Väänänen, Francesca De Lorenzo, Maria H Jäntti, Hengjing Cui, Marta Chavero-Pieres, Tommi P Kilpeläinen, Christina Mechtler, Reinis Svarcbahs, Erin Seppälä, Juha R Savinainen, Elena Puris, Gert Fricker, Mikko Gynther, Ulrika H Julku, Henri J Huttunen, Stephen J Haggarty, Timo T Myöhänen
A prolyl oligopeptidase inhibitor reduces tau pathology in cellular models and in mice with tauopathy. Science translational medicine 15 (691) (2023)
Tommi P Kilpeläinen, Henri T Pätsi, Reinis Svarcbahs, Ulrika H Julku, Tony S Eteläinen, Hengjing Cui, Samuli Auno, Nina H Sipari, Susanna Norrbacka, Teppo O Leino, Maria H Jäntti, Timo T Myöhänen, Erik A A Wallén
Nonpeptidic Oxazole-Based Prolyl Oligopeptidase Ligands with Disease-Modifying Effects on α-Synuclein Mouse Models of Parkinson's Disease. Journal of medicinal chemistry (2023)
Henri T Pätsi, Tommi P Kilpeläinen, Samuli Auno, Pyry M J Dillemuth, Khaled Arja, Maija K Lahtela-Kakkonen, Timo T Myöhänen, Erik A A Wallén
2-Imidazole as a Substitute for the Electrophilic Group Gives Highly Potent Prolyl Oligopeptidase Inhibitors. ACS medicinal chemistry letters 12 (10) (2021)